| Definition | Pyrococcus furiosus DSM 3638, complete genome. |
|---|---|
| Accession | NC_003413 |
| Length | 1,908,256 |
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The map label for this gene is dppD [H]
Identifier: 18976732
GI number: 18976732
Start: 373975
End: 374949
Strand: Direct
Name: dppD [H]
Synonym: PF0360
Alternate gene names: 18976732
Gene position: 373975-374949 (Clockwise)
Preceding gene: 18976731
Following gene: 18976733
Centisome position: 19.6
GC content: 46.05
Gene sequence:
>975_bases GTGATTGTGCTTGAGGTGAGGAATCTCAGGATTTATTATTCAACTCCAGTTGGTTTTGTAAAAGCAGTTGATGGAGTAAG TTTCGAAGTCAAGAAGGGGGAAGTGTTTGGAATTGCTGGAGAGAGCCGTTGTGGGAAATCAACCCTCGTCCACTCCCTAA TCCTCAGAAAACCACCAATGACACACAAAGGCGGAAAAGCAATCTTCAAGGGGAAAGACTTAATGAAACTCTCGAGGGAG GAGGCAAGAAAAATCCAATACAAGGAGTTATCAATAATCCCACAATACGCAATGAACGCCCTAAACCCAACGAAAAAAAT CAAGGACATAGTGTGGGACTTAGCCAGAGAGCACGGCATGCAAGATAGAGAGGAAGTCGAAAAACTCTTGAAAGAAAGAC TAAGCATGGTAAAACTCTCACCAAAGGTCGCCGAAATGTACCCAGTGGAATTGAGTGGAGGAATGAGGCAGAGAGCCACA ATGGTAGTCTCAACCCTCCTAAACCCAGACTTGCTAATTGCTGATGAAATAACATCAGCCCTAGACGTGACGACACAAAG AGTTGTCATTGAATTACTCCACTACTTCATGCAGGAGGGGATTGTAAAATCAATAATCTTCGTTACACACGATCTAGCCT TGCTAAAACAGATTGCAGACAGGGTTATGGTGATGTACGCGGGGAAGGTTGTTGAAATCGGGCCAATGGAGGAGGTTTTA GAATCCCCAGCCCACCCCTACACGCAAATGCTCCTCGACTCCCTCCCAAGAATGGGTGTACACTACAAGAGGCAAAAACT CCACGGAATCCCAGGTTATCCAATAAGCCTACTAAACCCACCCCAAGGTTGCAGATTCTACACAAGATGCCCCTACGCAA TGGAACACTGTCCAAAAATAGAGCCAAAATTAGTCCAAGTCTCCAAAGAGCATTACGCAGCCTGCCACCTCCTCGGGGGT GAGGGAAGTGCTTGA
Upstream 100 bases:
>100_bases GGTTCATTCCACCAGGATTGTTTATAACTCTCATAATCACAGCGTTGTTCTTTGTGAATCTCGGTCTTGAGGAGGTTTTT AATCCGAGGTTGAGGAGGGA
Downstream 100 bases:
>100_bases ACTCGAGAATGTGACAAAAACCTTCACCTCGGGACTCTTTGGTGGATATGAGATTAGGGCAGTGGATGGAGTATCATTCA AGGTTGAGGAGGGTGAGATA
Product: oligopeptide ABC transporter
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 324; Mature: 324
Protein sequence:
>324_residues MIVLEVRNLRIYYSTPVGFVKAVDGVSFEVKKGEVFGIAGESRCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSRE EARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRAT MVVSTLLNPDLLIADEITSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVL ESPAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGG EGSA
Sequences:
>Translated_324_residues MIVLEVRNLRIYYSTPVGFVKAVDGVSFEVKKGEVFGIAGESRCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSRE EARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRAT MVVSTLLNPDLLIADEITSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVL ESPAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGG EGSA >Mature_324_residues MIVLEVRNLRIYYSTPVGFVKAVDGVSFEVKKGEVFGIAGESRCGKSTLVHSLILRKPPMTHKGGKAIFKGKDLMKLSRE EARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGMQDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRAT MVVSTLLNPDLLIADEITSALDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVL ESPAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKIEPKLVQVSKEHYAACHLLGG EGSA
Specific function: Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI42490749, Length=248, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI21536376, Length=221, Percent_Identity=27.6018099547511, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI47078218, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI45446740, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI27436953, Length=231, Percent_Identity=27.7056277056277, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI48994883, Length=315, Percent_Identity=37.7777777777778, Blast_Score=209, Evalue=1e-55, Organism=Escherichia coli, GI1787500, Length=314, Percent_Identity=36.624203821656, Blast_Score=193, Evalue=2e-50, Organism=Escherichia coli, GI1789962, Length=291, Percent_Identity=37.4570446735395, Blast_Score=189, Evalue=2e-49, Organism=Escherichia coli, GI1789963, Length=319, Percent_Identity=35.1097178683386, Blast_Score=189, Evalue=2e-49, Organism=Escherichia coli, GI1787759, Length=320, Percent_Identity=35.9375, Blast_Score=180, Evalue=9e-47, Organism=Escherichia coli, GI1787548, Length=329, Percent_Identity=33.1306990881459, Blast_Score=167, Evalue=1e-42, Organism=Escherichia coli, GI145693107, Length=266, Percent_Identity=34.5864661654135, Blast_Score=155, Evalue=4e-39, Organism=Escherichia coli, GI1787758, Length=285, Percent_Identity=32.9824561403509, Blast_Score=153, Evalue=2e-38, Organism=Escherichia coli, GI1788506, Length=259, Percent_Identity=32.4324324324324, Blast_Score=139, Evalue=3e-34, Organism=Escherichia coli, GI48994997, Length=253, Percent_Identity=31.2252964426877, Blast_Score=128, Evalue=6e-31, Organism=Escherichia coli, GI1789032, Length=243, Percent_Identity=33.7448559670782, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1786398, Length=252, Percent_Identity=30.1587301587302, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1789891, Length=210, Percent_Identity=34.2857142857143, Blast_Score=111, Evalue=8e-26, Organism=Escherichia coli, GI1787547, Length=255, Percent_Identity=31.3725490196078, Blast_Score=104, Evalue=7e-24, Organism=Escherichia coli, GI1789890, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87081791, Length=267, Percent_Identity=29.5880149812734, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788225, Length=265, Percent_Identity=26.7924528301887, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI1787029, Length=256, Percent_Identity=26.5625, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI87081834, Length=231, Percent_Identity=31.1688311688312, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1786698, Length=222, Percent_Identity=30.1801801801802, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1788761, Length=288, Percent_Identity=24.6527777777778, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI1789991, Length=236, Percent_Identity=27.1186440677966, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081709, Length=245, Percent_Identity=25.3061224489796, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786345, Length=218, Percent_Identity=31.1926605504587, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787972, Length=223, Percent_Identity=30.9417040358744, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1788644, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI48994943, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1790739, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI48995001, Length=238, Percent_Identity=28.9915966386555, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789672, Length=261, Percent_Identity=25.6704980842912, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788450, Length=244, Percent_Identity=24.5901639344262, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1787712, Length=230, Percent_Identity=30, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1786872, Length=212, Percent_Identity=29.2452830188679, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787112, Length=254, Percent_Identity=27.9527559055118, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI87082267, Length=259, Percent_Identity=25.8687258687259, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787105, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87081782, Length=243, Percent_Identity=25.1028806584362, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786703, Length=232, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=1e-12, Organism=Escherichia coli, GI1787089, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789586, Length=240, Percent_Identity=26.25, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787792, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1787370, Length=240, Percent_Identity=25.8333333333333, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=28.755364806867, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17567265, Length=229, Percent_Identity=28.82096069869, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71984940, Length=244, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI115533608, Length=231, Percent_Identity=25.1082251082251, Blast_Score=68, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193208177, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71983523, Length=234, Percent_Identity=23.9316239316239, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71983516, Length=234, Percent_Identity=23.9316239316239, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71983510, Length=234, Percent_Identity=23.9316239316239, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17567269, Length=228, Percent_Identity=27.1929824561404, Blast_Score=64, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17543740, Length=244, Percent_Identity=26.6393442622951, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=237, Percent_Identity=23.2067510548523, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324985, Length=256, Percent_Identity=24.21875, Blast_Score=63, Evalue=8e-11, Organism=Drosophila melanogaster, GI221512771, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI85726357, Length=233, Percent_Identity=25.3218884120172, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574150, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI116007328, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24643674, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 36513; Mature: 36513
Theoretical pI: Translated: 9.34; Mature: 9.34
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 4.9 %Met (Translated Protein) 6.5 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 4.9 %Met (Mature Protein) 6.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIVLEVRNLRIYYSTPVGFVKAVDGVSFEVKKGEVFGIAGESRCGKSTLVHSLILRKPPM CEEEEEEEEEEEEECCCHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCCCC THKGGKAIFKGKDLMKLSREEARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGM CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC QDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMVVSTLLNPDLLIADEITSA CCHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH LDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHH ESPAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKI CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCCEEEECCCHHHHHCCCC EPKLVQVSKEHYAACHLLGGEGSA CHHHHHHHHHHHHEEEEECCCCCC >Mature Secondary Structure MIVLEVRNLRIYYSTPVGFVKAVDGVSFEVKKGEVFGIAGESRCGKSTLVHSLILRKPPM CEEEEEEEEEEEEECCCHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHHHHHHHCCCCC THKGGKAIFKGKDLMKLSREEARKIQYKELSIIPQYAMNALNPTKKIKDIVWDLAREHGM CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC QDREEVEKLLKERLSMVKLSPKVAEMYPVELSGGMRQRATMVVSTLLNPDLLIADEITSA CCHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH LDVTTQRVVIELLHYFMQEGIVKSIIFVTHDLALLKQIADRVMVMYAGKVVEIGPMEEVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHH ESPAHPYTQMLLDSLPRMGVHYKRQKLHGIPGYPISLLNPPQGCRFYTRCPYAMEHCPKI CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCCEEEECCCHHHHHCCCC EPKLVQVSKEHYAACHLLGGEGSA CHHHHHHHHHHHHEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 1766370; 9384377 [H]