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The map label for this gene is trkA [H]

Identifier: 18976547

GI number: 18976547

Start: 185009

End: 185701

Strand: Direct

Name: trkA [H]

Synonym: PF0175

Alternate gene names: 18976547

Gene position: 185009-185701 (Clockwise)

Preceding gene: 18976546

Following gene: 33359456

Centisome position: 9.7

GC content: 38.67

Gene sequence:

>693_bases
ATGTATGTAATAATCATGGGGGCAGGTAGAATTGGAACTCTGGTTGCTAAAATGCTAGAAAACTCTGGTCATGACGTTGC
TATAATAGAAATGAACAAAGATAGGGCTCGAGCAGTTTCTGACATTGTTTCGGGGCTTGTAATTGAGGGCGATGCAACCG
ATCAAAACATCTTGGAGTCAGCAAACGTTAGAAATGCAGATGCCTTTGTAGCTTTAACGGGAAAAGATGATGCAAATATT
TTGGCTTGTATCTTGGCAAAACATCTGAATCCAAGAATAATGACGATACTCAGGATAACTGATCCCAGGAAGAAGAAGAT
ATTTGAGGAAGTTAAAGACCTCAAAAAATACTTTGATGTAGTTGTATCTCCCGAGGATATTGCTGCAAATTACATCTTTA
GAGTAGTTATAACCCCAGGATTTGATAGGGTTCTATTGCCAAGAGAAGGTGCAGAAATAATTCAATTCCACATAGATGAA
AACAGCAAGGTGGCAGGAAAGGCAGTAAAGGATCTCAACCTTCCACGGGATTCCCTTATCATAGCAATTTACGATGAGAA
AGGAAACTTAATAATTCCTTCAGGAGAAACAATCCTACCAAAGAGAGGGACTGTTGTCGTTTTTGCAAAGGATTCTGCCT
TAAAAGAGATTAAAAAGATAATGGAAGAAAAGGTTGAAGAGTCTGAAGAGTGA

Upstream 100 bases:

>100_bases
CCTTTACAACAATTCTTGGTGTTTTAGTTGGAATATTCATTACGAGGCCTGCTTATGGAGAGATTGCAAAAGTCTTAATT
GGAGAAAGGAGGTGAAATAA

Downstream 100 bases:

>100_bases
ACTTTTATTCAAATTTTTATCCTCAATGTTTATAAATCGTATTCAGCAACAACTTTTGGCTTTTTCATCATCATAAAATG
GGGATGATGATCATGGAGGA

Product: trk system potassium uptake - like protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MYVIIMGAGRIGTLVAKMLENSGHDVAIIEMNKDRARAVSDIVSGLVIEGDATDQNILESANVRNADAFVALTGKDDANI
LACILAKHLNPRIMTILRITDPRKKKIFEEVKDLKKYFDVVVSPEDIAANYIFRVVITPGFDRVLLPREGAEIIQFHIDE
NSKVAGKAVKDLNLPRDSLIIAIYDEKGNLIIPSGETILPKRGTVVVFAKDSALKEIKKIMEEKVEESEE

Sequences:

>Translated_230_residues
MYVIIMGAGRIGTLVAKMLENSGHDVAIIEMNKDRARAVSDIVSGLVIEGDATDQNILESANVRNADAFVALTGKDDANI
LACILAKHLNPRIMTILRITDPRKKKIFEEVKDLKKYFDVVVSPEDIAANYIFRVVITPGFDRVLLPREGAEIIQFHIDE
NSKVAGKAVKDLNLPRDSLIIAIYDEKGNLIIPSGETILPKRGTVVVFAKDSALKEIKKIMEEKVEESEE
>Mature_230_residues
MYVIIMGAGRIGTLVAKMLENSGHDVAIIEMNKDRARAVSDIVSGLVIEGDATDQNILESANVRNADAFVALTGKDDANI
LACILAKHLNPRIMTILRITDPRKKKIFEEVKDLKKYFDVVVSPEDIAANYIFRVVITPGFDRVLLPREGAEIIQFHIDE
NSKVAGKAVKDLNLPRDSLIIAIYDEKGNLIIPSGETILPKRGTVVVFAKDSALKEIKKIMEEKVEESEE

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=237, Percent_Identity=27.8481012658228, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 25455; Mature: 25455

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVIIMGAGRIGTLVAKMLENSGHDVAIIEMNKDRARAVSDIVSGLVIEGDATDQNILES
CEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCEEEECCCCCHHHHHH
ANVRNADAFVALTGKDDANILACILAKHLNPRIMTILRITDPRKKKIFEEVKDLKKYFDV
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHE
VVSPEDIAANYIFRVVITPGFDRVLLPREGAEIIQFHIDENSKVAGKAVKDLNLPRDSLI
EECCHHHHHEEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEE
IAIYDEKGNLIIPSGETILPKRGTVVVFAKDSALKEIKKIMEEKVEESEE
EEEEECCCCEECCCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYVIIMGAGRIGTLVAKMLENSGHDVAIIEMNKDRARAVSDIVSGLVIEGDATDQNILES
CEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCEEEECCCCCHHHHHH
ANVRNADAFVALTGKDDANILACILAKHLNPRIMTILRITDPRKKKIFEEVKDLKKYFDV
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHE
VVSPEDIAANYIFRVVITPGFDRVLLPREGAEIIQFHIDENSKVAGKAVKDLNLPRDSLI
EECCHHHHHEEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEE
IAIYDEKGNLIIPSGETILPKRGTVVVFAKDSALKEIKKIMEEKVEESEE
EEEEECCCCEECCCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]