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The map label for this gene is secD [C]

Identifier: 18976546

GI number: 18976546

Start: 183486

End: 185003

Strand: Direct

Name: secD [C]

Synonym: PF0174

Alternate gene names: 18976546

Gene position: 183486-185003 (Clockwise)

Preceding gene: 18976545

Following gene: 18976547

Centisome position: 9.62

GC content: 39.39

Gene sequence:

>1518_bases
ATGAAGTGGAGGAGAATTTTACTTAATTTTAGGGTCATTGTTCTCATATTCTTCCTCTTGATCTCAATAACAGCCCTAGC
TACGAGAGGTTTAACTTTTGGTTTAGACATTAGTGGAGGAATATCCATAACTGTAAAGCTCGAAAAACCTGTGGATTCTC
AAACAATGGAGCAAGTTAAAATTGCATTGGAGCAGAGGTTAAATACGCTTGGTGTTAAGAATATAGTTGTTGAACCTTGG
GGAGATCAGTTTGTAATTGTTAAGGTGGCTAATGTAACGGAAGAAGAAGCTGATCAACTAATAAAGACTATTGAAAGACA
GGGAGTTTTCTATGCTGAATTTCAGGGTATTATTTTTGCAACAGGAAAAGACATTTTGAATGTTGGAAGCGTTAGCTATG
ATCCTCAGCACAGTGCTTGGGTAGTTCCATTTAGACTCTCAAAGGAAGCTGCAGAAAAGTTTGCCCAACTTGCCTTAGGA
AAAGCGGGATATCCAGTGGATATGTTCCTAGATCCTCCTGTGAACTCAACTTTAGTTGTTTCTAATAGAGTGTACGAGGC
AATGCTCTCTAAAACATTCATGTTGGAAGGAGATATGACACTTGTCGAAAGAATAGAGAAAGCCTTTGGCATTAAGGTTG
TGCCCTATGCTAATGTTACCCCAGAAGAGATTGCTGAGATTGCTAAGGGGAGTGAGAGAATAATATTGCTTGATGTGGAT
GGAAATCTCTCAAAAGCTCTTAAAGAGATGGGCTTTGAAGTTGAAACAAGAAGTATGAGAAGTGATGAAGACGTTTATGA
TTTCATTAAAAGATCTCTTGGCTTATATGGACCTTACAGAGTTTCAGAGGGATTAGCTACTGGGAATCCAAGTACTGAAG
TCATGATATCAATCACAGCACCTAAAACTGACATTCAAGCTAGACAAGATGCTCAAGTAGTTTCTGTAGTTTTGAGGAGC
GGATCACTTCCTGTAAAGCTCTCAATAGAGAGAATTGACTACATCTCTCCAAAATTGGGAGAGAATTTCAAGAGGCAAGT
TCTAGTTGCGGGAATTGCAGCGTTGCTTGTTGTTGGGTTAATAGTCTTCTTACATTACAGAAAAATTAAGATAGCCATCC
CCGTAATGTTCACGAGCTTTAGTGAAGTGTTGATTATCTTGGGTATTGCAGCACTCATTCGTTGGAACTTGGATTTGCCA
AGCATTGCGGGAATTATTGCGGCAATAGGAACTGGAGTTGATCAGCAAATTGTCATAACGGATGAACTTTTAGGAGAGGA
AGAAAGCAGAAGAAGAGTAAAGAGGAGTGGAGTGTTGAGAAGGATGGGTAGAGCGTTCTTCATAATCCTAGCTTCAGCTA
CAACAACTATAGTTGCCATGAGCTTTCTCTTTAAGTTCTTCGTTGGTGGACTTAGAGGATTTGCCTTTACAACAATTCTT
GGTGTTTTAGTTGGAATATTCATTACGAGGCCTGCTTATGGAGAGATTGCAAAAGTCTTAATTGGAGAAAGGAGGTGA

Upstream 100 bases:

>100_bases
CTTCAGTTCTCATATTTGGATTGCTTGCTGACTTTATGAACACTTGGATTTTAAATGCAGGAGTTTTGCGTTTATACATA
GCTAAGAGGGAGGGTAAGGA

Downstream 100 bases:

>100_bases
AATAAATGTATGTAATAATCATGGGGGCAGGTAGAATTGGAACTCTGGTTGCTAAAATGCTAGAAAACTCTGGTCATGAC
GTTGCTATAATAGAAATGAA

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MKWRRILLNFRVIVLIFFLLISITALATRGLTFGLDISGGISITVKLEKPVDSQTMEQVKIALEQRLNTLGVKNIVVEPW
GDQFVIVKVANVTEEEADQLIKTIERQGVFYAEFQGIIFATGKDILNVGSVSYDPQHSAWVVPFRLSKEAAEKFAQLALG
KAGYPVDMFLDPPVNSTLVVSNRVYEAMLSKTFMLEGDMTLVERIEKAFGIKVVPYANVTPEEIAEIAKGSERIILLDVD
GNLSKALKEMGFEVETRSMRSDEDVYDFIKRSLGLYGPYRVSEGLATGNPSTEVMISITAPKTDIQARQDAQVVSVVLRS
GSLPVKLSIERIDYISPKLGENFKRQVLVAGIAALLVVGLIVFLHYRKIKIAIPVMFTSFSEVLIILGIAALIRWNLDLP
SIAGIIAAIGTGVDQQIVITDELLGEEESRRRVKRSGVLRRMGRAFFIILASATTTIVAMSFLFKFFVGGLRGFAFTTIL
GVLVGIFITRPAYGEIAKVLIGERR

Sequences:

>Translated_505_residues
MKWRRILLNFRVIVLIFFLLISITALATRGLTFGLDISGGISITVKLEKPVDSQTMEQVKIALEQRLNTLGVKNIVVEPW
GDQFVIVKVANVTEEEADQLIKTIERQGVFYAEFQGIIFATGKDILNVGSVSYDPQHSAWVVPFRLSKEAAEKFAQLALG
KAGYPVDMFLDPPVNSTLVVSNRVYEAMLSKTFMLEGDMTLVERIEKAFGIKVVPYANVTPEEIAEIAKGSERIILLDVD
GNLSKALKEMGFEVETRSMRSDEDVYDFIKRSLGLYGPYRVSEGLATGNPSTEVMISITAPKTDIQARQDAQVVSVVLRS
GSLPVKLSIERIDYISPKLGENFKRQVLVAGIAALLVVGLIVFLHYRKIKIAIPVMFTSFSEVLIILGIAALIRWNLDLP
SIAGIIAAIGTGVDQQIVITDELLGEEESRRRVKRSGVLRRMGRAFFIILASATTTIVAMSFLFKFFVGGLRGFAFTTIL
GVLVGIFITRPAYGEIAKVLIGERR
>Mature_505_residues
MKWRRILLNFRVIVLIFFLLISITALATRGLTFGLDISGGISITVKLEKPVDSQTMEQVKIALEQRLNTLGVKNIVVEPW
GDQFVIVKVANVTEEEADQLIKTIERQGVFYAEFQGIIFATGKDILNVGSVSYDPQHSAWVVPFRLSKEAAEKFAQLALG
KAGYPVDMFLDPPVNSTLVVSNRVYEAMLSKTFMLEGDMTLVERIEKAFGIKVVPYANVTPEEIAEIAKGSERIILLDVD
GNLSKALKEMGFEVETRSMRSDEDVYDFIKRSLGLYGPYRVSEGLATGNPSTEVMISITAPKTDIQARQDAQVVSVVLRS
GSLPVKLSIERIDYISPKLGENFKRQVLVAGIAALLVVGLIVFLHYRKIKIAIPVMFTSFSEVLIILGIAALIRWNLDLP
SIAGIIAAIGTGVDQQIVITDELLGEEESRRRVKRSGVLRRMGRAFFIILASATTTIVAMSFLFKFFVGGLRGFAFTTIL
GVLVGIFITRPAYGEIAKVLIGERR

Specific function: Involved In Protein Export. [C]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=207, Percent_Identity=30.9178743961353, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022646 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 55814; Mature: 55814

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWRRILLNFRVIVLIFFLLISITALATRGLTFGLDISGGISITVKLEKPVDSQTMEQVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHHHHH
IALEQRLNTLGVKNIVVEPWGDQFVIVKVANVTEEEADQLIKTIERQGVFYAEFQGIIFA
HHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCEEEE
TGKDILNVGSVSYDPQHSAWVVPFRLSKEAAEKFAQLALGKAGYPVDMFLDPPVNSTLVV
CCCHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEE
SNRVYEAMLSKTFMLEGDMTLVERIEKAFGIKVVPYANVTPEEIAEIAKGSERIILLDVD
HHHHHHHHHHHHEEECCCHHHHHHHHHHHCEEEEECCCCCHHHHHHHHCCCCEEEEEECC
GNLSKALKEMGFEVETRSMRSDEDVYDFIKRSLGLYGPYRVSEGLATGNPSTEVMISITA
CCHHHHHHHCCCEEEHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEEEEEC
PKTDIQARQDAQVVSVVLRSGSLPVKLSIERIDYISPKLGENFKRQVLVAGIAALLVVGL
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVFLHYRKIKIAIPVMFTSFSEVLIILGIAALIRWNLDLPSIAGIIAAIGTGVDQQIVIT
HHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEE
DELLGEEESRRRVKRSGVLRRMGRAFFIILASATTTIVAMSFLFKFFVGGLRGFAFTTIL
HHHHCCHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLVGIFITRPAYGEIAKVLIGERR
HHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKWRRILLNFRVIVLIFFLLISITALATRGLTFGLDISGGISITVKLEKPVDSQTMEQVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHHHHH
IALEQRLNTLGVKNIVVEPWGDQFVIVKVANVTEEEADQLIKTIERQGVFYAEFQGIIFA
HHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCEEEE
TGKDILNVGSVSYDPQHSAWVVPFRLSKEAAEKFAQLALGKAGYPVDMFLDPPVNSTLVV
CCCHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEE
SNRVYEAMLSKTFMLEGDMTLVERIEKAFGIKVVPYANVTPEEIAEIAKGSERIILLDVD
HHHHHHHHHHHHEEECCCHHHHHHHHHHHCEEEEECCCCCHHHHHHHHCCCCEEEEEECC
GNLSKALKEMGFEVETRSMRSDEDVYDFIKRSLGLYGPYRVSEGLATGNPSTEVMISITA
CCHHHHHHHCCCEEEHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEEEEEEC
PKTDIQARQDAQVVSVVLRSGSLPVKLSIERIDYISPKLGENFKRQVLVAGIAALLVVGL
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVFLHYRKIKIAIPVMFTSFSEVLIILGIAALIRWNLDLPSIAGIIAAIGTGVDQQIVIT
HHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEE
DELLGEEESRRRVKRSGVLRRMGRAFFIILASATTTIVAMSFLFKFFVGGLRGFAFTTIL
HHHHCCHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLVGIFITRPAYGEIAKVLIGERR
HHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]