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The map label for this gene is tldD [C]

Identifier: 18976532

GI number: 18976532

Start: 170595

End: 171968

Strand: Direct

Name: tldD [C]

Synonym: PF0160

Alternate gene names: 18976532

Gene position: 170595-171968 (Clockwise)

Preceding gene: 18976526

Following gene: 18976533

Centisome position: 8.94

GC content: 39.52

Gene sequence:

>1374_bases
ATGAACATTGATGTTGACAAAATAATCAAAACAGCGGAAGCTTATGCTGAACGTTATGGTGTGAAATTCTTCGACATAAG
AATTGAAAGATACACATTCTCCACTGTGGATGTTGAGAATTTAGAAGTGAGCAAAGTTCGCCAAGATTCCGAAGTAGGGA
TGGGTGTTAGAGCTCTAGGCAAAGGTTGGGGGTTTTCTTCAACAAGCGATATTAAAGAGTTCGAGAGTGCAATTAAAAAC
GCCATGAAGTTGTCTAAATTTTCTGACTATAACGTTACAATTTACCAAGGGGATCCCATTGTTGATAAGGCCGAGATAAA
AGAAAGATTACCTCTGTTTGATATTTCTCTTGAGGAAAAGGTAGATTTAGGGATGAAATTAGCTAAGGAAATGCAGAGAG
AATACATTAAGAGCGTTAAGGTTTCATACTATGAAGAGATAGTTGAAAAGTTATACTTGAGTTCTGAAGGAAGCCAGATA
ATGACGAAGATCCCGAGAGTTCTTCTCACGCTTTCAGCTGTAGCTAGAAGAGGAGATATAATGCAAACTTATTGGAAGTC
AGTTGGAGGAACTGGAGGGTTCGAAATAATTAAAAGTTATGACGTTTACTCCTGGGCAAAGAAAATCAGTGAAAAAGCAG
TGAGTTTGCTTTCTGCGAAGTCCCCTCCATCAGGAAAAATGGACGTATTGATAGATCCAGAGCTTGCGGGAGTTTTTATT
CATGAGGCCATAGGACATGCTGCTGAAGGAGATGCGATTAAAGATAATAGTAGTATCTTTGTGGGACTACTTGGAAAGAA
AGTAGGGGTAGAAGAGCTGACAGTAGTTGATGATCCCACCCTGGAGGGAAAATTTGGATCTTATATCTATGATGATGAAG
GCCAGCCTGGGGGGAGAGTCGAAATAATAAAGAACGGGATTCTTAATTCTTTTCTTACTGATAGAGAAAGTTCTTTGGTC
TTGGAAATGCCTCCTAATGGTCATGGACGGGCTGAAGATTATGGAAGTAGACCTCTTGTTAGAATGTCAAACACCTACAT
AGAGCCGGGAGATTGGAAATTTGAGGAAATGATTGAAGAAATGAAGAGGGGAGTTTACATGCTGGGAGATAAGGGTGGAG
AAGTTGACATAGTGAATGGCACATTTACATTTGGAGCAAAAGAGGGGTATTTAATAGAAAATGGAGAAATTAAACATCAG
CTCAGAGATGTTGCGCTTTCTGGGAAGATACTTGAAATATTAAAAGAAATAAGAGCTATTGGAAATGACTTACGCATAGA
ATTTCCAGGATACTGTGGAAAGGGCCAATGGGTTCCAGTTGATGATGGTGGGCCGCATGTTTTATTGAAAGCAATTGTAG
GTGGTCTTCAATGA

Upstream 100 bases:

>100_bases
GTAGTCGTTCCAGTCTTTTTCTCCATATGCACCACCTAACAAAATTTTAGCTGGAACACTTTTTAAGTTCTCTCTTTATA
GGGAGAAGGGGGACTGGAGG

Downstream 100 bases:

>100_bases
TTCCCGAATACCTAATCAAGAAGCTAGAAGAGTTGAATATAGAATGGGAAATTTATGCTGAAAAGTATTGGATAACGTCG
GTTAAAGCAAAAAAGCGTGA

Product: TLDD - like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNIDVDKIIKTAEAYAERYGVKFFDIRIERYTFSTVDVENLEVSKVRQDSEVGMGVRALGKGWGFSSTSDIKEFESAIKN
AMKLSKFSDYNVTIYQGDPIVDKAEIKERLPLFDISLEEKVDLGMKLAKEMQREYIKSVKVSYYEEIVEKLYLSSEGSQI
MTKIPRVLLTLSAVARRGDIMQTYWKSVGGTGGFEIIKSYDVYSWAKKISEKAVSLLSAKSPPSGKMDVLIDPELAGVFI
HEAIGHAAEGDAIKDNSSIFVGLLGKKVGVEELTVVDDPTLEGKFGSYIYDDEGQPGGRVEIIKNGILNSFLTDRESSLV
LEMPPNGHGRAEDYGSRPLVRMSNTYIEPGDWKFEEMIEEMKRGVYMLGDKGGEVDIVNGTFTFGAKEGYLIENGEIKHQ
LRDVALSGKILEILKEIRAIGNDLRIEFPGYCGKGQWVPVDDGGPHVLLKAIVGGLQ

Sequences:

>Translated_457_residues
MNIDVDKIIKTAEAYAERYGVKFFDIRIERYTFSTVDVENLEVSKVRQDSEVGMGVRALGKGWGFSSTSDIKEFESAIKN
AMKLSKFSDYNVTIYQGDPIVDKAEIKERLPLFDISLEEKVDLGMKLAKEMQREYIKSVKVSYYEEIVEKLYLSSEGSQI
MTKIPRVLLTLSAVARRGDIMQTYWKSVGGTGGFEIIKSYDVYSWAKKISEKAVSLLSAKSPPSGKMDVLIDPELAGVFI
HEAIGHAAEGDAIKDNSSIFVGLLGKKVGVEELTVVDDPTLEGKFGSYIYDDEGQPGGRVEIIKNGILNSFLTDRESSLV
LEMPPNGHGRAEDYGSRPLVRMSNTYIEPGDWKFEEMIEEMKRGVYMLGDKGGEVDIVNGTFTFGAKEGYLIENGEIKHQ
LRDVALSGKILEILKEIRAIGNDLRIEFPGYCGKGQWVPVDDGGPHVLLKAIVGGLQ
>Mature_457_residues
MNIDVDKIIKTAEAYAERYGVKFFDIRIERYTFSTVDVENLEVSKVRQDSEVGMGVRALGKGWGFSSTSDIKEFESAIKN
AMKLSKFSDYNVTIYQGDPIVDKAEIKERLPLFDISLEEKVDLGMKLAKEMQREYIKSVKVSYYEEIVEKLYLSSEGSQI
MTKIPRVLLTLSAVARRGDIMQTYWKSVGGTGGFEIIKSYDVYSWAKKISEKAVSLLSAKSPPSGKMDVLIDPELAGVFI
HEAIGHAAEGDAIKDNSSIFVGLLGKKVGVEELTVVDDPTLEGKFGSYIYDDEGQPGGRVEIIKNGILNSFLTDRESSLV
LEMPPNGHGRAEDYGSRPLVRMSNTYIEPGDWKFEEMIEEMKRGVYMLGDKGGEVDIVNGTFTFGAKEGYLIENGEIKHQ
LRDVALSGKILEILKEIRAIGNDLRIEFPGYCGKGQWVPVDDGGPHVLLKAIVGGLQ

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=414, Percent_Identity=33.5748792270531, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1790682, Length=427, Percent_Identity=22.4824355971897, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50768; Mature: 50768

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDVDKIIKTAEAYAERYGVKFFDIRIERYTFSTVDVENLEVSKVRQDSEVGMGVRALG
CCCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEEECCCCHHHHHCCHHHCCCHHHHC
KGWGFSSTSDIKEFESAIKNAMKLSKFSDYNVTIYQGDPIVDKAEIKERLPLFDISLEEK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCCEEECCHHHH
VDLGMKLAKEMQREYIKSVKVSYYEEIVEKLYLSSEGSQIMTKIPRVLLTLSAVARRGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
MQTYWKSVGGTGGFEIIKSYDVYSWAKKISEKAVSLLSAKSPPSGKMDVLIDPELAGVFI
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHH
HEAIGHAAEGDAIKDNSSIFVGLLGKKVGVEELTVVDDPTLEGKFGSYIYDDEGQPGGRV
HHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCEE
EIIKNGILNSFLTDRESSLVLEMPPNGHGRAEDYGSRPLVRMSNTYIEPGDWKFEEMIEE
EEEHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHH
MKRGVYMLGDKGGEVDIVNGTFTFGAKEGYLIENGEIKHQLRDVALSGKILEILKEIRAI
HHCCEEEEECCCCEEEEEECEEEECCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHC
GNDLRIEFPGYCGKGQWVPVDDGGPHVLLKAIVGGLQ
CCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNIDVDKIIKTAEAYAERYGVKFFDIRIERYTFSTVDVENLEVSKVRQDSEVGMGVRALG
CCCCHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEEECCCCHHHHHCCHHHCCCHHHHC
KGWGFSSTSDIKEFESAIKNAMKLSKFSDYNVTIYQGDPIVDKAEIKERLPLFDISLEEK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCCEEECCHHHH
VDLGMKLAKEMQREYIKSVKVSYYEEIVEKLYLSSEGSQIMTKIPRVLLTLSAVARRGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
MQTYWKSVGGTGGFEIIKSYDVYSWAKKISEKAVSLLSAKSPPSGKMDVLIDPELAGVFI
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHH
HEAIGHAAEGDAIKDNSSIFVGLLGKKVGVEELTVVDDPTLEGKFGSYIYDDEGQPGGRV
HHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCEE
EIIKNGILNSFLTDRESSLVLEMPPNGHGRAEDYGSRPLVRMSNTYIEPGDWKFEEMIEE
EEEHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHH
MKRGVYMLGDKGGEVDIVNGTFTFGAKEGYLIENGEIKHQLRDVALSGKILEILKEIRAI
HHCCEEEEECCCCEEEEEECEEEECCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHC
GNDLRIEFPGYCGKGQWVPVDDGGPHVLLKAIVGGLQ
CCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]