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The map label for this gene is wtpB [H]

Identifier: 18976453

GI number: 18976453

Start: 86517

End: 87308

Strand: Direct

Name: wtpB [H]

Synonym: PF0081

Alternate gene names: 18976453

Gene position: 86517-87308 (Clockwise)

Preceding gene: 18976452

Following gene: 18976454

Centisome position: 4.53

GC content: 40.53

Gene sequence:

>792_bases
ATGAGGCAAAGTTTAATAACGAGCACTGCTTATCTTTTTCCGATGGATAGAAGAGACTACTTAGCTTACGCCTTTGCAGG
ATTAGGGGCATTCTTAGTGGCATTTATTGGCCTTCCCTTATTCATGATTTTCATAAAGCAAGCATACGATCTTGAAGCTC
TACAGAGGACATTAGTTGATCCATTGGTTATTGAGTCAATTAGAAATTCTCTATTTACAGCAACTGTTTCAACCCTCCTG
GGAATTCTCTTTGGTGTTCCCTTGGGCTATGTCTTAGCGAGAAAGGAATTCAAGGGTAAAAATTTTGTTCAAGCTCTTAT
CGACACTCCAATTGTAATCCCTCACTCTGTTGTTGGAATAATGCTCCTTGTTACATTTTCCGATGCAATTCTTGACAACT
ATAAGGGAATAGTGGCAGTGATGTTGTTTGTGTCTTCCCCATTCATAGTGAACTCCGCTAGGGATGGCTTCTTAAGTGTC
GATGAAAAGCTTGAATACGTAGCAAGAACATTGGGTGCTTCTGGACTAAGAACTTTCTTTTCTGTGACACTTCCAAATGC
TATTCATTCTATAGCAAGTGGGGCAATTATGGCTTGGGCAAGGGCAATAAGTGAAGTTGGTGCTATTTTGATAGTTGCCT
ATTATCCAAAGACGGCTCAAGTTCTGATTATGGAGTACTTCAACAATTATGGACTTAGGGCCTCTAGACCAATTGCAGTT
ATTTTAGTTACGATAAGCCTTGCAGTGTTCATTTTCCTACGGTGGCTAGTTGGGAGGGGGAGAAATGCTTGA

Upstream 100 bases:

>100_bases
TCTAGAACCTCCAATAGCATTTGGAAATGTGCCCGAGGAATTGAAGCCTCTGGTCTCGATTGAAAAGTGAATGTTTTTGT
TTTGCATTTTTATTTAACGT

Downstream 100 bases:

>100_bases
AGTGCAAGGAATATCAAAGAAGTGGAAAGACTTTCATCTAAAGGATATAAGCTTCTCGGTAATGGATGGAGAGTATTTCA
TAGTCCTTGGCCCTAGCGGG

Product: sulfate/thiosulfate transport-like protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRQSLITSTAYLFPMDRRDYLAYAFAGLGAFLVAFIGLPLFMIFIKQAYDLEALQRTLVDPLVIESIRNSLFTATVSTLL
GILFGVPLGYVLARKEFKGKNFVQALIDTPIVIPHSVVGIMLLVTFSDAILDNYKGIVAVMLFVSSPFIVNSARDGFLSV
DEKLEYVARTLGASGLRTFFSVTLPNAIHSIASGAIMAWARAISEVGAILIVAYYPKTAQVLIMEYFNNYGLRASRPIAV
ILVTISLAVFIFLRWLVGRGRNA

Sequences:

>Translated_263_residues
MRQSLITSTAYLFPMDRRDYLAYAFAGLGAFLVAFIGLPLFMIFIKQAYDLEALQRTLVDPLVIESIRNSLFTATVSTLL
GILFGVPLGYVLARKEFKGKNFVQALIDTPIVIPHSVVGIMLLVTFSDAILDNYKGIVAVMLFVSSPFIVNSARDGFLSV
DEKLEYVARTLGASGLRTFFSVTLPNAIHSIASGAIMAWARAISEVGAILIVAYYPKTAQVLIMEYFNNYGLRASRPIAV
ILVTISLAVFIFLRWLVGRGRNA
>Mature_263_residues
MRQSLITSTAYLFPMDRRDYLAYAFAGLGAFLVAFIGLPLFMIFIKQAYDLEALQRTLVDPLVIESIRNSLFTATVSTLL
GILFGVPLGYVLARKEFKGKNFVQALIDTPIVIPHSVVGIMLLVTFSDAILDNYKGIVAVMLFVSSPFIVNSARDGFLSV
DEKLEYVARTLGASGLRTFFSVTLPNAIHSIASGAIMAWARAISEVGAILIVAYYPKTAQVLIMEYFNNYGLRASRPIAV
ILVTISLAVFIFLRWLVGRGRNA

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=261, Percent_Identity=26.8199233716475, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788764, Length=169, Percent_Identity=26.6272189349112, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786980, Length=165, Percent_Identity=32.7272727272727, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28947; Mature: 28947

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSLITSTAYLFPMDRRDYLAYAFAGLGAFLVAFIGLPLFMIFIKQAYDLEALQRTLVD
CCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PLVIESIRNSLFTATVSTLLGILFGVPLGYVLARKEFKGKNFVQALIDTPIVIPHSVVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHH
MLLVTFSDAILDNYKGIVAVMLFVSSPFIVNSARDGFLSVDEKLEYVARTLGASGLRTFF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHH
SVTLPNAIHSIASGAIMAWARAISEVGAILIVAYYPKTAQVLIMEYFNNYGLRASRPIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHH
ILVTISLAVFIFLRWLVGRGRNA
HHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRQSLITSTAYLFPMDRRDYLAYAFAGLGAFLVAFIGLPLFMIFIKQAYDLEALQRTLVD
CCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
PLVIESIRNSLFTATVSTLLGILFGVPLGYVLARKEFKGKNFVQALIDTPIVIPHSVVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHH
MLLVTFSDAILDNYKGIVAVMLFVSSPFIVNSARDGFLSVDEKLEYVARTLGASGLRTFF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHH
SVTLPNAIHSIASGAIMAWARAISEVGAILIVAYYPKTAQVLIMEYFNNYGLRASRPIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHH
ILVTISLAVFIFLRWLVGRGRNA
HHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA