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The map label for this gene is wtpA

Identifier: 18976452

GI number: 18976452

Start: 85449

End: 86486

Strand: Direct

Name: wtpA

Synonym: PF0080

Alternate gene names: 18976452

Gene position: 85449-86486 (Clockwise)

Preceding gene: 18976449

Following gene: 18976453

Centisome position: 4.48

GC content: 39.5

Gene sequence:

>1038_bases
ATGCGAGAGGGTGGTGTAATGAAGAAAAGACTTTTAGCTCTAATAGTTGCTTTTGCGGTATTAACTGCTGGGTGTTTGGG
AAGTGAGAGCAAAGAAGTTACACTGATAGTATTTCACGCAGGTTCTCTAAGTGTTCCCTTCCAAGAAGTTGAGAAGGAAT
TCTCTGAATATGCTGAAAGAAACCTCGGGATTAAGGTGTCATTCCAAGACGAAGCCAGTGGAAGCGTTATGGCAGTTAGG
AAGGTCACAGATTTAGGGAGAAAAGCTGATGTAATTGGAGTGGCAGATTACACTTTAATACCCCAGCTATTGATACCAAA
CTACACGGATTTCTATGTCCTTTTTGCAACAAATGAAATTGTAATAGCATTCACAGATAAGAGCAGGTATGTAGAAGAAA
TGAAAAGCAATCCGGATAAATGGTATGAAATTCTGGCTAGGGAAGATGTAAGATTTGGATTCAGCGATCCAAACCAAGAT
CCCTGTGGCTACCGTTCTCTTATGGTAATAAAGTTAGCGGATTTGTATTATGGAAAGGAGATATTCAAAGAGCTTATTGA
AGAAAATACAAACATCTATTCAAATGGAACGCAGATCTACGCTCCTAAGGAGATTACAGTTAATCCTGGCAAGATTGTGA
TTAGACCAAAAGAAACAGATCTCCTAGGTCTAGTTGAAAGTGGAAGCATTGACTACATCTTCATCTATAAAAGCGTTGCC
AAACAGCATAATCTTTCTTACATAACTCTTCCTAGTGAAATAAACTTGGGAGATTTTAGCAAAGAGAAATTCTACGGTCA
GATCTCGATAACCTTGGGCTCTACTGGAAAGACAATAAAAGCCAAGCCAATAGTTTATGGAGTGACCGTACTGAAAGACG
CTCCTAATAGGGAAGTGGCCATAGAATTTCTGAGATATCTCCTGAGCGAGAATGGAAAAAGAATATTTGAAAAGAACCAC
CAGGACTTTCTAGAACCTCCAATAGCATTTGGAAATGTGCCCGAGGAATTGAAGCCTCTGGTCTCGATTGAAAAGTGA

Upstream 100 bases:

>100_bases
CATAGCTATTAATAAATCTTCCTTTTCCGTTACTTATTTAAATAAAATTATTTAACTTAAAACCAAAAGTTAAAACAAAA
TTTTTAAACATGGAATTTTA

Downstream 100 bases:

>100_bases
ATGTTTTTGTTTTGCATTTTTATTTAACGTATGAGGCAAAGTTTAATAACGAGCACTGCTTATCTTTTTCCGATGGATAG
AAGAGACTACTTAGCTTACG

Product: molybdate ABC transporter periplasmic substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MREGGVMKKRLLALIVAFAVLTAGCLGSESKEVTLIVFHAGSLSVPFQEVEKEFSEYAERNLGIKVSFQDEASGSVMAVR
KVTDLGRKADVIGVADYTLIPQLLIPNYTDFYVLFATNEIVIAFTDKSRYVEEMKSNPDKWYEILAREDVRFGFSDPNQD
PCGYRSLMVIKLADLYYGKEIFKELIEENTNIYSNGTQIYAPKEITVNPGKIVIRPKETDLLGLVESGSIDYIFIYKSVA
KQHNLSYITLPSEINLGDFSKEKFYGQISITLGSTGKTIKAKPIVYGVTVLKDAPNREVAIEFLRYLLSENGKRIFEKNH
QDFLEPPIAFGNVPEELKPLVSIEK

Sequences:

>Translated_345_residues
MREGGVMKKRLLALIVAFAVLTAGCLGSESKEVTLIVFHAGSLSVPFQEVEKEFSEYAERNLGIKVSFQDEASGSVMAVR
KVTDLGRKADVIGVADYTLIPQLLIPNYTDFYVLFATNEIVIAFTDKSRYVEEMKSNPDKWYEILAREDVRFGFSDPNQD
PCGYRSLMVIKLADLYYGKEIFKELIEENTNIYSNGTQIYAPKEITVNPGKIVIRPKETDLLGLVESGSIDYIFIYKSVA
KQHNLSYITLPSEINLGDFSKEKFYGQISITLGSTGKTIKAKPIVYGVTVLKDAPNREVAIEFLRYLLSENGKRIFEKNH
QDFLEPPIAFGNVPEELKPLVSIEK
>Mature_345_residues
MREGGVMKKRLLALIVAFAVLTAGCLGSESKEVTLIVFHAGSLSVPFQEVEKEFSEYAERNLGIKVSFQDEASGSVMAVR
KVTDLGRKADVIGVADYTLIPQLLIPNYTDFYVLFATNEIVIAFTDKSRYVEEMKSNPDKWYEILAREDVRFGFSDPNQD
PCGYRSLMVIKLADLYYGKEIFKELIEENTNIYSNGTQIYAPKEITVNPGKIVIRPKETDLLGLVESGSIDYIFIYKSVA
KQHNLSYITLPSEINLGDFSKEKFYGQISITLGSTGKTIKAKPIVYGVTVLKDAPNREVAIEFLRYLLSENGKRIFEKNH
QDFLEPPIAFGNVPEELKPLVSIEK

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate, with a preference for tungstate

COG id: COG0725

COG function: function code P; ABC-type molybdate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WTPA_PYRFU (Q8U4K5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_577809.1
- PDB:   3CG1
- PDBsum:   3CG1
- ProteinModelPortal:   Q8U4K5
- EnsemblBacteria:   EBPYRT00000004969
- GeneID:   1467909
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF0080
- NMPDR:   fig|186497.1.peg.80
- GeneTree:   EBGT00050000022680
- HOGENOM:   HBG457285
- OMA:   NEMAITW
- ProtClustDB:   PRK04168
- BRENDA:   3.6.3.29
- InterPro:   IPR022498
- InterPro:   IPR006059
- TIGRFAMs:   TIGR03730

Pfam domain/function: PF01547 SBP_bac_1

EC number: NA

Molecular weight: Translated: 38801; Mature: 38801

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGGVMKKRLLALIVAFAVLTAGCLGSESKEVTLIVFHAGSLSVPFQEVEKEFSEYAER
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHH
NLGIKVSFQDEASGSVMAVRKVTDLGRKADVIGVADYTLIPQLLIPNYTDFYVLFATNEI
CCCEEEEECCCCCCCEEEEEHHHHCCCCCCEEEECHHHHHHHHHCCCCCCEEEEEEECEE
VIAFTDKSRYVEEMKSNPDKWYEILAREDVRFGFSDPNQDPCGYRSLMVIKLADLYYGKE
EEEEECCHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHEEEEEHHHHHHHHH
IFKELIEENTNIYSNGTQIYAPKEITVNPGKIVIRPKETDLLGLVESGSIDYIFIYKSVA
HHHHHHHCCCCEEECCEEEEECCEEEECCCEEEEEECCCCEEEEEECCCCCEEEEEEHHH
KQHNLSYITLPSEINLGDFSKEKFYGQISITLGSTGKTIKAKPIVYGVTVLKDAPNREVA
HHCCCEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCEEEEEEEECCCCCHHHH
IEFLRYLLSENGKRIFEKNHQDFLEPPIAFGNVPEELKPLVSIEK
HHHHHHHHHCCCCCHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MREGGVMKKRLLALIVAFAVLTAGCLGSESKEVTLIVFHAGSLSVPFQEVEKEFSEYAER
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHH
NLGIKVSFQDEASGSVMAVRKVTDLGRKADVIGVADYTLIPQLLIPNYTDFYVLFATNEI
CCCEEEEECCCCCCCEEEEEHHHHCCCCCCEEEECHHHHHHHHHCCCCCCEEEEEEECEE
VIAFTDKSRYVEEMKSNPDKWYEILAREDVRFGFSDPNQDPCGYRSLMVIKLADLYYGKE
EEEEECCHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHEEEEEHHHHHHHHH
IFKELIEENTNIYSNGTQIYAPKEITVNPGKIVIRPKETDLLGLVESGSIDYIFIYKSVA
HHHHHHHCCCCEEECCEEEEECCEEEECCCEEEEEECCCCEEEEEECCCCCEEEEEEHHH
KQHNLSYITLPSEINLGDFSKEKFYGQISITLGSTGKTIKAKPIVYGVTVLKDAPNREVA
HHCCCEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCEEEEEEEECCCCCHHHH
IEFLRYLLSENGKRIFEKNHQDFLEPPIAFGNVPEELKPLVSIEK
HHHHHHHHHCCCCCHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA