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The map label for this gene is yabD [H]

Identifier: 18311502

GI number: 18311502

Start: 2884602

End: 2885372

Strand: Reverse

Name: yabD [H]

Synonym: CPE2520

Alternate gene names: 18311502

Gene position: 2885372-2884602 (Counterclockwise)

Preceding gene: 18311503

Following gene: 18311501

Centisome position: 95.18

GC content: 29.18

Gene sequence:

>771_bases
ATGAAATATAAAATATTTGATACACATGCACATTATGACTCAGATAGTTTTGATGAAGATAGAGAAAATGTAATAAAAGA
ACTACAAGAAAATGGAGTTATTGGGGTTTTAAATTGTGGATCTGATCTTTATGGATTAAGAAAATCAGTTGAACTTGCAA
AAGAGTTTGATATGTTTTATGCCGCAGTTGGTATACATCCAGAAAATGCAGATGAATTTAATGAGGATGTTGTAAAAGAA
ATAAAAGAATTTGTTAAGAATGAAAAGGTTAAAGCCATTGGAGAAATAGGACTAGATTATTATTGGGAAGAAAATCCTCC
AAGAGAAGTTCAAAAAGAAGTTTTTAGAGCTCAAATGAAGTTAGCTGATGAATTAAATTTACCAGTTGTTATACATGATA
GAGATGCTCATAAAGACACTTTAGAAATTATGAAGGAGTTTCCAAATGTAATTGGAGTAGTACATTGTTTTTCAGGTTCA
GTTGAATTTGCAAAAGAGTGCATTAAATTAGGATATTACATTGGATTTACAGGAGTTTTAACATTTAAAAATGCTAAAAA
ATTAGTAGATGTTTGTAGAGAAATACCTGCTGAAAGAATGCTAGTTGAGACTGACTGTCCTTTTATGGCACCAGTTCCTT
TTAGGGGCAAAAGAAACAAGTCAGATTATATTGAATATATCATAGATAAAATGAGTGAAATAAGAGGAATTTCAGGTGAA
GAAATGAATGAAATCTTATTAAACAATAAAAAGAGATTGTTCAAAATTTAA

Upstream 100 bases:

>100_bases
TAAGGCAATAACTTGGTTAGGAGCTTTATTAGGAGGAATTCTAGGAATTTTATCACCACTTTTATCTACAATTTATATGT
AAAATTCAAAGGAGAAAATT

Downstream 100 bases:

>100_bases
TATAACCATAACTAAACTAAAGAAAAATAAATGTAATAACATGGAAAGTACACTAATATAATATAGTGTACTTTTTTAAA
TATAAATCAACCGTTATTTA

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKYKIFDTHAHYDSDSFDEDRENVIKELQENGVIGVLNCGSDLYGLRKSVELAKEFDMFYAAVGIHPENADEFNEDVVKE
IKEFVKNEKVKAIGEIGLDYYWEENPPREVQKEVFRAQMKLADELNLPVVIHDRDAHKDTLEIMKEFPNVIGVVHCFSGS
VEFAKECIKLGYYIGFTGVLTFKNAKKLVDVCREIPAERMLVETDCPFMAPVPFRGKRNKSDYIEYIIDKMSEIRGISGE
EMNEILLNNKKRLFKI

Sequences:

>Translated_256_residues
MKYKIFDTHAHYDSDSFDEDRENVIKELQENGVIGVLNCGSDLYGLRKSVELAKEFDMFYAAVGIHPENADEFNEDVVKE
IKEFVKNEKVKAIGEIGLDYYWEENPPREVQKEVFRAQMKLADELNLPVVIHDRDAHKDTLEIMKEFPNVIGVVHCFSGS
VEFAKECIKLGYYIGFTGVLTFKNAKKLVDVCREIPAERMLVETDCPFMAPVPFRGKRNKSDYIEYIIDKMSEIRGISGE
EMNEILLNNKKRLFKI
>Mature_256_residues
MKYKIFDTHAHYDSDSFDEDRENVIKELQENGVIGVLNCGSDLYGLRKSVELAKEFDMFYAAVGIHPENADEFNEDVVKE
IKEFVKNEKVKAIGEIGLDYYWEENPPREVQKEVFRAQMKLADELNLPVVIHDRDAHKDTLEIMKEFPNVIGVVHCFSGS
VEFAKECIKLGYYIGFTGVLTFKNAKKLVDVCREIPAERMLVETDCPFMAPVPFRGKRNKSDYIEYIIDKMSEIRGISGE
EMNEILLNNKKRLFKI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=32.3308270676692, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI225903424, Length=165, Percent_Identity=39.3939393939394, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI225903439, Length=245, Percent_Identity=32.6530612244898, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=26.615969581749, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=26.5151515151515, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=26.9372693726937, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=23.921568627451, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=26.7543859649123, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=36.046511627907, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=31.2741312741313, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=30.8880308880309, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17559024, Length=215, Percent_Identity=32.093023255814, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=25.4752851711027, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=214, Percent_Identity=29.4392523364486, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648690, Length=214, Percent_Identity=30.3738317757009, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24586117, Length=213, Percent_Identity=32.3943661971831, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330018, Length=213, Percent_Identity=32.3943661971831, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29592; Mature: 29592

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKIFDTHAHYDSDSFDEDRENVIKELQENGVIGVLNCGSDLYGLRKSVELAKEFDMFY
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
AAVGIHPENADEFNEDVVKEIKEFVKNEKVKAIGEIGLDYYWEENPPREVQKEVFRAQMK
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHH
LADELNLPVVIHDRDAHKDTLEIMKEFPNVIGVVHCFSGSVEFAKECIKLGYYIGFTGVL
HHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
TFKNAKKLVDVCREIPAERMLVETDCPFMAPVPFRGKRNKSDYIEYIIDKMSEIRGISGE
EHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
EMNEILLNNKKRLFKI
HHHHHHHCCCHHHHCC
>Mature Secondary Structure
MKYKIFDTHAHYDSDSFDEDRENVIKELQENGVIGVLNCGSDLYGLRKSVELAKEFDMFY
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
AAVGIHPENADEFNEDVVKEIKEFVKNEKVKAIGEIGLDYYWEENPPREVQKEVFRAQMK
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHH
LADELNLPVVIHDRDAHKDTLEIMKEFPNVIGVVHCFSGSVEFAKECIKLGYYIGFTGVL
HHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEE
TFKNAKKLVDVCREIPAERMLVETDCPFMAPVPFRGKRNKSDYIEYIIDKMSEIRGISGE
EHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
EMNEILLNNKKRLFKI
HHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]