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The map label for this gene is resD [H]

Identifier: 18311470

GI number: 18311470

Start: 2849186

End: 2849872

Strand: Reverse

Name: resD [H]

Synonym: CPE2488

Alternate gene names: 18311470

Gene position: 2849872-2849186 (Counterclockwise)

Preceding gene: 18311471

Following gene: 18311469

Centisome position: 94.01

GC content: 32.31

Gene sequence:

>687_bases
ATGGAAGGTTTATTAGGAAAGATTTTAATTGTAGACGACGATGAGAATATATGTGAAGTCATAAAAATGTATCTAGAAAC
TACAGGATATAACGTTAAAGTAGCTCATGATGGAAAGGCTGCTAAAGAAGAATTTGTTAACTTTAGCCCTAACCTAGTTG
TATTAGATATGATGCTACCTGGAATTGATGGAATGGAAGTATTAAAGTGGATAAGAAAAGATAGTAACGTTCCAGTAATA
ATGTTAACTGCTAAAGGAGAAACTTTTGATAAGGTATTAGCTTTAGAAATCGGTGCAGATGACTATGTAGTTAAACCTTT
TGAACCAAAAGAATTATTAGCTAGAGTAAAAGCGGTTATGAGAAGATATTCAGGAGAAGAGCCAGATAATGTAGTATTAA
ACTTCCCAGGTTTAACTATAGATGCTAACTCATATAAAGTTATATACAATGGAGAAGAAGTTAAAACTCCTCCTAAAGAA
TTTGAACTTTTACACTATCTTGCAAGTAACAAGAATAAAGTTTTCACAAGAGATCAATTATTATGTGAAGTTTGGGGATA
TGATTACCCAGGTTATTCAAGAACTGTTGATGTTCACATAAAGAGATTAAGAGAAAAATTAAACGGTGGAGAAGACTGGC
AACTTGAAACTGTTTGGGGTGTTGGGTATAAATTTGAGGTGAAATAA

Upstream 100 bases:

>100_bases
TATGTTAAATGAAAATATTTCATGTTTTTAAAGTATAAAACTGCATAAAATAAGGACAAATGTAGAATAGTTACAGAAAG
GATTTTAAGAGGTGAATTTT

Downstream 100 bases:

>100_bases
TGAGATGTCGTGGCTTAGTTCCAAAGTTAATCTTAACACTAAGCGTAACAATATGCATTACTTTCTTTATTGTAGGTATA
ATACTTTCTAGCTTGTTTAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEGLLGKILIVDDDENICEVIKMYLETTGYNVKVAHDGKAAKEEFVNFSPNLVVLDMMLPGIDGMEVLKWIRKDSNVPVI
MLTAKGETFDKVLALEIGADDYVVKPFEPKELLARVKAVMRRYSGEEPDNVVLNFPGLTIDANSYKVIYNGEEVKTPPKE
FELLHYLASNKNKVFTRDQLLCEVWGYDYPGYSRTVDVHIKRLREKLNGGEDWQLETVWGVGYKFEVK

Sequences:

>Translated_228_residues
MEGLLGKILIVDDDENICEVIKMYLETTGYNVKVAHDGKAAKEEFVNFSPNLVVLDMMLPGIDGMEVLKWIRKDSNVPVI
MLTAKGETFDKVLALEIGADDYVVKPFEPKELLARVKAVMRRYSGEEPDNVVLNFPGLTIDANSYKVIYNGEEVKTPPKE
FELLHYLASNKNKVFTRDQLLCEVWGYDYPGYSRTVDVHIKRLREKLNGGEDWQLETVWGVGYKFEVK
>Mature_228_residues
MEGLLGKILIVDDDENICEVIKMYLETTGYNVKVAHDGKAAKEEFVNFSPNLVVLDMMLPGIDGMEVLKWIRKDSNVPVI
MLTAKGETFDKVLALEIGADDYVVKPFEPKELLARVKAVMRRYSGEEPDNVVLNFPGLTIDANSYKVIYNGEEVKTPPKE
FELLHYLASNKNKVFTRDQLLCEVWGYDYPGYSRTVDVHIKRLREKLNGGEDWQLETVWGVGYKFEVK

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=42.9203539823009, Blast_Score=187, Evalue=4e-49,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=37.0044052863436, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=36.7713004484305, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=39.0350877192982, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36.4444444444444, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=37.0535714285714, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=34.8017621145374, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.0807174887892, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=35, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=32.1428571428571, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=34.4036697247706, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.981981981982, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=35.1931330472103, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=32.5892857142857, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=32.8467153284672, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26029; Mature: 26029

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLLGKILIVDDDENICEVIKMYLETTGYNVKVAHDGKAAKEEFVNFSPNLVVLDMMLP
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEEEECC
GIDGMEVLKWIRKDSNVPVIMLTAKGETFDKVLALEIGADDYVVKPFEPKELLARVKAVM
CCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHH
RRYSGEEPDNVVLNFPGLTIDANSYKVIYNGEEVKTPPKEFELLHYLASNKNKVFTRDQL
HHHCCCCCCCEEEECCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEHHHH
LCEVWGYDYPGYSRTVDVHIKRLREKLNGGEDWQLETVWGVGYKFEVK
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEC
>Mature Secondary Structure
MEGLLGKILIVDDDENICEVIKMYLETTGYNVKVAHDGKAAKEEFVNFSPNLVVLDMMLP
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEEEECC
GIDGMEVLKWIRKDSNVPVIMLTAKGETFDKVLALEIGADDYVVKPFEPKELLARVKAVM
CCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHH
RRYSGEEPDNVVLNFPGLTIDANSYKVIYNGEEVKTPPKEFELLHYLASNKNKVFTRDQL
HHHCCCCCCCEEEECCCEEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEHHHH
LCEVWGYDYPGYSRTVDVHIKRLREKLNGGEDWQLETVWGVGYKFEVK
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]