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The map label for this gene is degP [H]

Identifier: 18311468

GI number: 18311468

Start: 2846599

End: 2847756

Strand: Reverse

Name: degP [H]

Synonym: CPE2486

Alternate gene names: 18311468

Gene position: 2847756-2846599 (Counterclockwise)

Preceding gene: 18311469

Following gene: 18311467

Centisome position: 93.94

GC content: 29.27

Gene sequence:

>1158_bases
ATGGGGAATTTTTTTAAGAACTCTAAAAAGGGGAAGGATCTCCATGGAGTAAATGAAAAAAACTATGACAATATAGTGAT
TAAAAAGGATAAAAAAAGGTTTTGGATAAAGAGCTTATTAAAGTTAGTTAGTTTTGTTATTCTAGTTGTTTTAGTGAGTT
TTATTGCCTTTAAACACTATACTAAAGATTTAACCATGAAAGAGCAAAAAGCAAATCTTTTAAATGAAATAAAAGATGGT
AGATATGATATAACCAATTTAGTAAATAAATCAGGATGTAGTTTAGTTACAATCGGTGATGACAGTAATAACTTAGCTAT
AGGAAAAGATGATGGTAAAAATGTTTCTGGATCTATCATAAGAACAGATGGGTACATAATAACTAGTTATAGTGCAATAA
AGGATTTTTCAAAAGTCTATGTAAAAATATCAAGTAATGATATAAGTCCTTTTGAGGCTAGAATTGTTGGATTTGATAAG
GATACTGACATTGCAGTATTAAAAATAGGGGCTAATGGATTAAAAAGTATTTCAACATCAGAATTAGAGGTTCTAGAAAT
AGGCGAAAAAGTTGCAACCTTAGGAAATACAACAAGTGAGGAACCTGTAGGTTTTGTATCTAATGGAATAGTTAGTGCGC
CTATAAAGAAAACAAGCGTAGGAGAAGAAGGTCATTCTGATTCTAAGGTCTTTGATCTTATAGAAACTAATTCTTTAATA
AATTCAGATAATAATAGTGGTATATTATGTGACTATAATGGAGTTGTTATTGGTATAAATAGTTTATATTTTACTAATAA
ATTTTCTAAACCAGGAATATATTATGCCTTAGAAATAAATGATGCTTTAAGAATAGCAGATTCTATAATAAGAAAAGGTG
GCGTAACTGCAAGCGTAACCTTAGGGGTTACAGGATCTACTGTTGCAGATGAAAAGAGCAATATTTATGGAATTTATGTA
GAAGATGTTGATAAAGGTAGCAATGCCTTTAATGCAGGAATAAAACCAACTGATATAATAGTTGAAGCTGATAATGAGAA
GGTTAAGAATATAGAAAGCTTAGCTGACTTATTGAAAAAACATTCTGTAGGTGACATAATTAAACTTAAAGTTATAAGAG
GAGATACCACAAAGGATATTTCTGTAACTTTAAATTGA

Upstream 100 bases:

>100_bases
TTTGGGCTGAAAATGTCAAAGATAAAAATGGTGAAATAAAAGGTGTTAGATTTAATTTTACTTTAACTAAAGTTAAATAA
GTATTGCATAGGGGGTCTTT

Downstream 100 bases:

>100_bases
TTAAAAGAATATAACCCTTCACATAATTTAGTGAGGGGTTTTTTATTGTTTTATATTAATAGTAAAAGTATAATTAAAGA
ATGATTTAATTAAAAATTAA

Product: PDZ domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MGNFFKNSKKGKDLHGVNEKNYDNIVIKKDKKRFWIKSLLKLVSFVILVVLVSFIAFKHYTKDLTMKEQKANLLNEIKDG
RYDITNLVNKSGCSLVTIGDDSNNLAIGKDDGKNVSGSIIRTDGYIITSYSAIKDFSKVYVKISSNDISPFEARIVGFDK
DTDIAVLKIGANGLKSISTSELEVLEIGEKVATLGNTTSEEPVGFVSNGIVSAPIKKTSVGEEGHSDSKVFDLIETNSLI
NSDNNSGILCDYNGVVIGINSLYFTNKFSKPGIYYALEINDALRIADSIIRKGGVTASVTLGVTGSTVADEKSNIYGIYV
EDVDKGSNAFNAGIKPTDIIVEADNEKVKNIESLADLLKKHSVGDIIKLKVIRGDTTKDISVTLN

Sequences:

>Translated_385_residues
MGNFFKNSKKGKDLHGVNEKNYDNIVIKKDKKRFWIKSLLKLVSFVILVVLVSFIAFKHYTKDLTMKEQKANLLNEIKDG
RYDITNLVNKSGCSLVTIGDDSNNLAIGKDDGKNVSGSIIRTDGYIITSYSAIKDFSKVYVKISSNDISPFEARIVGFDK
DTDIAVLKIGANGLKSISTSELEVLEIGEKVATLGNTTSEEPVGFVSNGIVSAPIKKTSVGEEGHSDSKVFDLIETNSLI
NSDNNSGILCDYNGVVIGINSLYFTNKFSKPGIYYALEINDALRIADSIIRKGGVTASVTLGVTGSTVADEKSNIYGIYV
EDVDKGSNAFNAGIKPTDIIVEADNEKVKNIESLADLLKKHSVGDIIKLKVIRGDTTKDISVTLN
>Mature_384_residues
GNFFKNSKKGKDLHGVNEKNYDNIVIKKDKKRFWIKSLLKLVSFVILVVLVSFIAFKHYTKDLTMKEQKANLLNEIKDGR
YDITNLVNKSGCSLVTIGDDSNNLAIGKDDGKNVSGSIIRTDGYIITSYSAIKDFSKVYVKISSNDISPFEARIVGFDKD
TDIAVLKIGANGLKSISTSELEVLEIGEKVATLGNTTSEEPVGFVSNGIVSAPIKKTSVGEEGHSDSKVFDLIETNSLIN
SDNNSGILCDYNGVVIGINSLYFTNKFSKPGIYYALEINDALRIADSIIRKGGVTASVTLGVTGSTVADEKSNIYGIYVE
DVDKGSNAFNAGIKPTDIIVEADNEKVKNIESLADLLKKHSVGDIIKLKVIRGDTTKDISVTLN

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789629, Length=281, Percent_Identity=27.7580071174377, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786356, Length=269, Percent_Identity=27.8810408921933, Blast_Score=85, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646839, Length=292, Percent_Identity=25.3424657534247, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41844; Mature: 41713

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFFKNSKKGKDLHGVNEKNYDNIVIKKDKKRFWIKSLLKLVSFVILVVLVSFIAFKHY
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKDLTMKEQKANLLNEIKDGRYDITNLVNKSGCSLVTIGDDSNNLAIGKDDGKNVSGSII
HHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCEEE
RTDGYIITSYSAIKDFSKVYVKISSNDISPFEARIVGFDKDTDIAVLKIGANGLKSISTS
EECCEEEECHHHHHCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
ELEVLEIGEKVATLGNTTSEEPVGFVSNGIVSAPIKKTSVGEEGHSDSKVFDLIETNSLI
CCHHHHHHHHHHHCCCCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCEEEEEHHCHHC
NSDNNSGILCDYNGVVIGINSLYFTNKFSKPGIYYALEINDALRIADSIIRKGGVTASVT
CCCCCCEEEEECCCEEEEECEEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCEEEEE
LGVTGSTVADEKSNIYGIYVEDVDKGSNAFNAGIKPTDIIVEADNEKVKNIESLADLLKK
EECCCCCCCCCCCCEEEEEEEECCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHH
HSVGDIIKLKVIRGDTTKDISVTLN
CCCCCEEEEEEEECCCCCEEEEEEC
>Mature Secondary Structure 
GNFFKNSKKGKDLHGVNEKNYDNIVIKKDKKRFWIKSLLKLVSFVILVVLVSFIAFKHY
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKDLTMKEQKANLLNEIKDGRYDITNLVNKSGCSLVTIGDDSNNLAIGKDDGKNVSGSII
HHCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCEEE
RTDGYIITSYSAIKDFSKVYVKISSNDISPFEARIVGFDKDTDIAVLKIGANGLKSISTS
EECCEEEECHHHHHCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
ELEVLEIGEKVATLGNTTSEEPVGFVSNGIVSAPIKKTSVGEEGHSDSKVFDLIETNSLI
CCHHHHHHHHHHHCCCCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCEEEEEHHCHHC
NSDNNSGILCDYNGVVIGINSLYFTNKFSKPGIYYALEINDALRIADSIIRKGGVTASVT
CCCCCCEEEEECCCEEEEECEEEEECCCCCCCEEEEEEECHHHHHHHHHHHCCCCEEEEE
LGVTGSTVADEKSNIYGIYVEDVDKGSNAFNAGIKPTDIIVEADNEKVKNIESLADLLKK
EECCCCCCCCCCCCEEEEEEEECCCCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHH
HSVGDIIKLKVIRGDTTKDISVTLN
CCCCCEEEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]