Click here to switch to the map view.

The map label for this gene is apbA [H]

Identifier: 18311209

GI number: 18311209

Start: 2548415

End: 2549443

Strand: Direct

Name: apbA [H]

Synonym: CPE2227

Alternate gene names: 18311209

Gene position: 2548415-2549443 (Clockwise)

Preceding gene: 18311208

Following gene: 18311215

Centisome position: 84.07

GC content: 27.5

Gene sequence:

>1029_bases
ATGGAGAACTTAAGACATATTTGTATTTTTCTATGTATGATTTTAACTTTCACTTTAAATGGATGCTCCATAAAAAAAGA
ACCTATAAGCAAATCTAGTTTTTTTATGGGGACAATAGTTAATATAACTTTATATGATAAATTTGATGAAGGAATCATAG
ATAAGGCATTTAATAAAATAAGTGAAATTGAATCATTGTTAAGTTTAAATATACAAAACTCTGAAATTAATAAAATAAAT
GAAAAGTCTGGTATAGAACCAGTAAAAGTTACCAAAACTACCTTTGACATAATAGAAAAATCACTAGAATACTCTAAAGC
TTCTAAAGGAAACTTTGATATAACTATTGGGCCTTTAGTTAAGCTATGGGGAATAGGAAGTGAAGATGCAAGAGTTCCTG
ATGATAATGAAATACTAGATACTATAAAATTAATAAATTATGAAAATATTATTTTAGATAAGGAAAATACCACTGTATTT
TTAAAAGAAGAAAATATGGTTTTAGACTTAGGTGCTATAGCTAAGGGATATATAGCAGATCTTATTTCAGATATATTAAT
AGATGAAGGTGTATCTAAAGCTATTATTGATTTAGGTGGCAATATTTTTGCCCTAGGTGAGAAAAATAAAAATGAAAATT
GGACAATAGGAATACAAAATCCTTTTGAAAACAGAGGTGCTCCCCTAGGAACTTTAAGTATATGCAATAAATCAGTAGTT
ACCTCTGGGATCTATGAACGTTATTTAGAAATTAATAATACTAAATATCATCACATTTTAAACCCTAAAACTGGATATCC
CTATGATAATAATTTAGCTTCTGTAACCATAGTTTCTTCAAAATCTATAGATGGTGATGCCCTTTCCACCTCAACCTTTG
GTATGGGCCTTTCAGATGGCTTAGAGCTAATTGAATCACTTCCTGAAATAGAAGGTATTTTTGTAACTAAATCTAAAGAA
ATCTTCATATCAAAGGGACTAAAAAATAATTTTAAATTACTTGATAATTCTTTTAAAATAGCAAATTAA

Upstream 100 bases:

>100_bases
AAATTAGCTGAGAAAGTATTAAAGAATGCTGAAGAAGGAAAAACTGAAGCAACTTTAGTAGACTAAGTAAAACATATTAT
CTTATTTCTAGGAGGGTAAA

Downstream 100 bases:

>100_bases
ACAAAAATTTATATAAATTATTAAAACATAGCTTTTTATTAAAATTAATATTTCCTTTAAATAAAAAGCTATGTTCTAAT
TAAATGTTTATTTAAAAAAC

Product: thiamin biosynthesis lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MENLRHICIFLCMILTFTLNGCSIKKEPISKSSFFMGTIVNITLYDKFDEGIIDKAFNKISEIESLLSLNIQNSEINKIN
EKSGIEPVKVTKTTFDIIEKSLEYSKASKGNFDITIGPLVKLWGIGSEDARVPDDNEILDTIKLINYENIILDKENTTVF
LKEENMVLDLGAIAKGYIADLISDILIDEGVSKAIIDLGGNIFALGEKNKNENWTIGIQNPFENRGAPLGTLSICNKSVV
TSGIYERYLEINNTKYHHILNPKTGYPYDNNLASVTIVSSKSIDGDALSTSTFGMGLSDGLELIESLPEIEGIFVTKSKE
IFISKGLKNNFKLLDNSFKIAN

Sequences:

>Translated_342_residues
MENLRHICIFLCMILTFTLNGCSIKKEPISKSSFFMGTIVNITLYDKFDEGIIDKAFNKISEIESLLSLNIQNSEINKIN
EKSGIEPVKVTKTTFDIIEKSLEYSKASKGNFDITIGPLVKLWGIGSEDARVPDDNEILDTIKLINYENIILDKENTTVF
LKEENMVLDLGAIAKGYIADLISDILIDEGVSKAIIDLGGNIFALGEKNKNENWTIGIQNPFENRGAPLGTLSICNKSVV
TSGIYERYLEINNTKYHHILNPKTGYPYDNNLASVTIVSSKSIDGDALSTSTFGMGLSDGLELIESLPEIEGIFVTKSKE
IFISKGLKNNFKLLDNSFKIAN
>Mature_342_residues
MENLRHICIFLCMILTFTLNGCSIKKEPISKSSFFMGTIVNITLYDKFDEGIIDKAFNKISEIESLLSLNIQNSEINKIN
EKSGIEPVKVTKTTFDIIEKSLEYSKASKGNFDITIGPLVKLWGIGSEDARVPDDNEILDTIKLINYENIILDKENTTVF
LKEENMVLDLGAIAKGYIADLISDILIDEGVSKAIIDLGGNIFALGEKNKNENWTIGIQNPFENRGAPLGTLSICNKSVV
TSGIYERYLEINNTKYHHILNPKTGYPYDNNLASVTIVSSKSIDGDALSTSTFGMGLSDGLELIESLPEIEGIFVTKSKE
IFISKGLKNNFKLLDNSFKIAN

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=324, Percent_Identity=25.6172839506173, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 37915; Mature: 37915

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLRHICIFLCMILTFTLNGCSIKKEPISKSSFFMGTIVNITLYDKFDEGIIDKAFNKI
CCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHH
SEIESLLSLNIQNSEINKINEKSGIEPVKVTKTTFDIIEKSLEYSKASKGNFDITIGPLV
HHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
KLWGIGSEDARVPDDNEILDTIKLINYENIILDKENTTVFLKEENMVLDLGAIAKGYIAD
HHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCEEEEHHHHHHHHHHH
LISDILIDEGVSKAIIDLGGNIFALGEKNKNENWTIGIQNPFENRGAPLGTLSICNKSVV
HHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHCCCCCEEHHHHHCHHHH
TSGIYERYLEINNTKYHHILNPKTGYPYDNNLASVTIVSSKSIDGDALSTSTFGMGLSDG
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHH
LELIESLPEIEGIFVTKSKEIFISKGLKNNFKLLDNSFKIAN
HHHHHHCCCCCEEEEECCCEEEEECCCCCCCEEECCCEECCC
>Mature Secondary Structure
MENLRHICIFLCMILTFTLNGCSIKKEPISKSSFFMGTIVNITLYDKFDEGIIDKAFNKI
CCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHH
SEIESLLSLNIQNSEINKINEKSGIEPVKVTKTTFDIIEKSLEYSKASKGNFDITIGPLV
HHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
KLWGIGSEDARVPDDNEILDTIKLINYENIILDKENTTVFLKEENMVLDLGAIAKGYIAD
HHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCEEEEHHHHHHHHHHH
LISDILIDEGVSKAIIDLGGNIFALGEKNKNENWTIGIQNPFENRGAPLGTLSICNKSVV
HHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHCCCCCEEHHHHHCHHHH
TSGIYERYLEINNTKYHHILNPKTGYPYDNNLASVTIVSSKSIDGDALSTSTFGMGLSDG
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHH
LELIESLPEIEGIFVTKSKEIFISKGLKNNFKLLDNSFKIAN
HHHHHHCCCCCEEEEECCCEEEEECCCCCCCEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]