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The map label for this gene is selD [H]

Identifier: 18311100

GI number: 18311100

Start: 2431123

End: 2431863

Strand: Reverse

Name: selD [H]

Synonym: CPE2118

Alternate gene names: 18311100

Gene position: 2431863-2431123 (Counterclockwise)

Preceding gene: 18311102

Following gene: 18311099

Centisome position: 80.22

GC content: 31.04

Gene sequence:

>741_bases
GTGGCATTAAATATAGTTTGTTTCCCTAATTGTCTAAATATGAATATATTAGGTGAAATATTAAGAGGGGGAGCAGATAA
GGTATTAGAGGCTGGAGCTGTAATAGTTGGAGGACATACCGTTCAAGATGATGAACCTAAATATGGTTTATCTGTTACAG
GAATTGTTCACCCAGATAAAGTTCTTAAAAACTATGGATCAGAGACAGGTGATATTTTAATATTAACTAAACCAATTGGT
CTTGGAATAATAAATACAGCTATTAAGGCTAAGATAGCTTCTAAGGAAGCTTATGAAAAAGCAGTAAAAGTAATGGCATA
TTTAAATAAGTATGCAGGTGAAATAATAACTGACTATAATATAACATCATGTACGGATATAACAGGATTTTCACTAATAG
GGCATGCATATGAAATGGCAGAACCATCTAAAAAAACCTTTAGAATCTTTAAAGATGCAATTCCATTTATTAAAGAAGCT
AAAGAATATGCTAGTATGGGATTAATACCAGCTGGGTGTTATGAGAATAAAAGATACTTAGAAGGAAAATATCTTCTAAA
TAATGTTGAAAGTTGGATGGAAGATATATTATTTGATCCTCAAACATCAGGTGGATTATTAATCAGTTGTAAAGAGAAAG
ATTACATAGACATACTAACTAGATTAGAAAAGTTAGAGGTAGAAAGTGCTGTTATAGGACGTGTTGAAGATTTCAATGAT
GCATATATAGTAGTAGAGTAA

Upstream 100 bases:

>100_bases
AGATTTCTTTACTCCAATAGTAGATGACCCATATACCTTTGGACAGATAGCTGCAGCAAACTCCTTAAGTGATGTTTATG
CCATGGGAGGAAAGCCTATA

Downstream 100 bases:

>100_bases
TTTTTAGGAGGATAACATGACAAAAGAACTTCTTAGAGCTTTGCCTAAGATAGATGAAATACTTGGTATTTTTAATGAGG
ACTTTTTAAATGAAAATGGG

Product: selenophosphate synthetase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MALNIVCFPNCLNMNILGEILRGGADKVLEAGAVIVGGHTVQDDEPKYGLSVTGIVHPDKVLKNYGSETGDILILTKPIG
LGIINTAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYNITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEA
KEYASMGLIPAGCYENKRYLEGKYLLNNVESWMEDILFDPQTSGGLLISCKEKDYIDILTRLEKLEVESAVIGRVEDFND
AYIVVE

Sequences:

>Translated_246_residues
MALNIVCFPNCLNMNILGEILRGGADKVLEAGAVIVGGHTVQDDEPKYGLSVTGIVHPDKVLKNYGSETGDILILTKPIG
LGIINTAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYNITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEA
KEYASMGLIPAGCYENKRYLEGKYLLNNVESWMEDILFDPQTSGGLLISCKEKDYIDILTRLEKLEVESAVIGRVEDFND
AYIVVE
>Mature_245_residues
ALNIVCFPNCLNMNILGEILRGGADKVLEAGAVIVGGHTVQDDEPKYGLSVTGIVHPDKVLKNYGSETGDILILTKPIGL
GIINTAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYNITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEAK
EYASMGLIPAGCYENKRYLEGKYLLNNVESWMEDILFDPQTSGGLLISCKEKDYIDILTRLEKLEVESAVIGRVEDFNDA
YIVVE

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=204, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI15011844, Length=155, Percent_Identity=27.0967741935484, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1788062, Length=247, Percent_Identity=32.3886639676113, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17543426, Length=230, Percent_Identity=30, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653602, Length=243, Percent_Identity=28.8065843621399, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653604, Length=243, Percent_Identity=28.8065843621399, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28574119, Length=208, Percent_Identity=27.8846153846154, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 27119; Mature: 26987

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNIVCFPNCLNMNILGEILRGGADKVLEAGAVIVGGHTVQDDEPKYGLSVTGIVHPDK
CEEEEEECCCCCCHHHHHHHHHCCHHHHHHCCEEEECCEEECCCCCCCCEEEEEEECHHH
VLKNYGSETGDILILTKPIGLGIINTAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYN
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC
ITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEAKEYASMGLIPAGCYENKRYL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
EGKYLLNNVESWMEDILFDPQTSGGLLISCKEKDYIDILTRLEKLEVESAVIGRVEDFND
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AYIVVE
EEEEEC
>Mature Secondary Structure 
ALNIVCFPNCLNMNILGEILRGGADKVLEAGAVIVGGHTVQDDEPKYGLSVTGIVHPDK
EEEEEECCCCCCHHHHHHHHHCCHHHHHHCCEEEECCEEECCCCCCCCEEEEEEECHHH
VLKNYGSETGDILILTKPIGLGIINTAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYN
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC
ITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEAKEYASMGLIPAGCYENKRYL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
EGKYLLNNVESWMEDILFDPQTSGGLLISCKEKDYIDILTRLEKLEVESAVIGRVEDFND
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AYIVVE
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA