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The map label for this gene is virI [H]

Identifier: 18311081

GI number: 18311081

Start: 2408055

End: 2408753

Strand: Reverse

Name: virI [H]

Synonym: CPE2099

Alternate gene names: 18311081

Gene position: 2408753-2408055 (Counterclockwise)

Preceding gene: 18311082

Following gene: 18311080

Centisome position: 79.46

GC content: 28.04

Gene sequence:

>699_bases
ATGGAAGAAAAGATTTTAATAATTGAGGATGAACCAGATATACAAAATATTTTAAGATACTCCTTTATGAAAGAGGGATT
TAAAGTTAGATGTGTTGATAAAGGAAGACAGGGTATAGATATATTTAAAGAGTTTAATCCTAGTTTAGTGATTTTAGATT
TGATGTTACCTGATATTAGTGGATTTGATGTTTGTAGAGAGTTAAATAAATTAAATGCAAATATTATAATGCTTACAGCT
AGAGATGATATTGTGGACAAGGTTCTAGGACTAGAGTTAGGAGCAGATGATTATATAACTAAACCCTTTGATATAAGAGA
ATGTGTAGCAAGAGTAAAGGTTGCATTAAGAAGAAAAGATAAATTTTTAAAGGAAAGCAATAAAATTAAAGTTAAAGATG
AATTCATAATTGGCCCTATTAAAATAAAAAGGCAGTCAAGAAAGGTTTATTTAAATGAAGAAGAGATAAGATTGAAGCCA
AAAGAAATAGAACTATTACTATATTTTTTAGATAATCCTAACATATCCTTATCTAGAGATCAGATATTAGATGGGGTATG
GGGAGAGGAGTATTTTGGAGATTTTAGAACTGTTGATGTTCATGTAAGAAGACTAAGACAAAAGCTTAATAATGAGGAAA
TAATAGAAACTATTTTTGGATTAGGATATATGTTTAAAGGTGAGAAACATGAAAGTTAA

Upstream 100 bases:

>100_bases
TTGATACACGCCTTTTTTTTATTTTGGTAAAGAGTTGATAACAATTAAATTTGAAAAATATAGTAAAATTAATTTAACTA
TGTAGGTAAAGGAGAAGGAT

Downstream 100 bases:

>100_bases
ACATAAATTCTCAGGAGGATTTTTAATAATATTTCTAATTGCCTTTATAATTTTAAACTGTTTTTTAGGTAAAGCTTTTA
TTAATTATCATGAAAATAAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEEKILIIEDEPDIQNILRYSFMKEGFKVRCVDKGRQGIDIFKEFNPSLVILDLMLPDISGFDVCRELNKLNANIIMLTA
RDDIVDKVLGLELGADDYITKPFDIRECVARVKVALRRKDKFLKESNKIKVKDEFIIGPIKIKRQSRKVYLNEEEIRLKP
KEIELLLYFLDNPNISLSRDQILDGVWGEEYFGDFRTVDVHVRRLRQKLNNEEIIETIFGLGYMFKGEKHES

Sequences:

>Translated_232_residues
MEEKILIIEDEPDIQNILRYSFMKEGFKVRCVDKGRQGIDIFKEFNPSLVILDLMLPDISGFDVCRELNKLNANIIMLTA
RDDIVDKVLGLELGADDYITKPFDIRECVARVKVALRRKDKFLKESNKIKVKDEFIIGPIKIKRQSRKVYLNEEEIRLKP
KEIELLLYFLDNPNISLSRDQILDGVWGEEYFGDFRTVDVHVRRLRQKLNNEEIIETIFGLGYMFKGEKHES
>Mature_232_residues
MEEKILIIEDEPDIQNILRYSFMKEGFKVRCVDKGRQGIDIFKEFNPSLVILDLMLPDISGFDVCRELNKLNANIIMLTA
RDDIVDKVLGLELGADDYITKPFDIRECVARVKVALRRKDKFLKESNKIKVKDEFIIGPIKIKRQSRKVYLNEEEIRLKP
KEIELLLYFLDNPNISLSRDQILDGVWGEEYFGDFRTVDVHVRRLRQKLNNEEIIETIFGLGYMFKGEKHES

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=38.0952380952381, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=34.7639484978541, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=37.719298245614, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=34.3478260869565, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=36.9565217391304, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=33.4782608695652, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=34.6491228070175, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=33.0434782608696, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=36.0869565217391, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=31.6964285714286, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=28.5087719298246, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=30.3964757709251, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.0924369747899, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27243; Mature: 27243

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKILIIEDEPDIQNILRYSFMKEGFKVRCVDKGRQGIDIFKEFNPSLVILDLMLPDIS
CCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCEEEEEEECCCCC
GFDVCRELNKLNANIIMLTARDDIVDKVLGLELGADDYITKPFDIRECVARVKVALRRKD
HHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFLKESNKIKVKDEFIIGPIKIKRQSRKVYLNEEEIRLKPKEIELLLYFLDNPNISLSRD
HHHHCCCCEEEEEEEEECCEEEEECCCEEEECHHHEEECCCEEEEEEEEECCCCCEECHH
QILDGVWGEEYFGDFRTVDVHVRRLRQKLNNEEIIETIFGLGYMFKGEKHES
HHHCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure
MEEKILIIEDEPDIQNILRYSFMKEGFKVRCVDKGRQGIDIFKEFNPSLVILDLMLPDIS
CCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCEEEEEEECCCCC
GFDVCRELNKLNANIIMLTARDDIVDKVLGLELGADDYITKPFDIRECVARVKVALRRKD
HHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFLKESNKIKVKDEFIIGPIKIKRQSRKVYLNEEEIRLKPKEIELLLYFLDNPNISLSRD
HHHHCCCCEEEEEEEEECCEEEEECCCEEEECHHHEEECCCEEEEEEEEECCCCCEECHH
QILDGVWGEEYFGDFRTVDVHVRRLRQKLNNEEIIETIFGLGYMFKGEKHES
HHHCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]