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The map label for this gene is yesN [H]

Identifier: 18311069

GI number: 18311069

Start: 2393660

End: 2395183

Strand: Reverse

Name: yesN [H]

Synonym: CPE2087

Alternate gene names: 18311069

Gene position: 2395183-2393660 (Counterclockwise)

Preceding gene: 18311070

Following gene: 18311068

Centisome position: 79.01

GC content: 25.26

Gene sequence:

>1524_bases
ATGTACAAGGTTATGCTAGCTGATGATGAGAATTTAATTTTACAAGGACTTGAGAATATAATTGAATGGGAAGAACTAGG
GTTAGAAATTGTAAATAAGGCAAGTAATGGTCAAGAAGCCATAGATAAATTTAAGGAAAATCCAGTTGATATAGTGGTAA
CTGATATTAATATGCCACAGGTTACTGGATTGGAGTTATTAAAGGAATTAAAGAAAATTAATTCTGATGTTAAGTTTATA
ATATTAAGTGGATATGATGATTTTTCTTATGCTAAGAAAGCAATAGAATTAGGTGTTGAAAACTATATATTAAAGCCTAT
AGATGAAGAAGAATTAGAAAAAACTTTAAAAAATACAATAAATAAAATAAAACAAGAAAAAGAAGAAAATAAATCAAGTT
TAGGAAAACATAATATTCTTATTAAACTTATAAAGGGTAAATTGGCTCAAGGTGAAATAGAGGAAAACAAAGAAGGCTTT
TATATGAATTTAAATTCAGAAAGATATTCTCTATGTATTATAAACACTAGAAGTAGATATGATAGTGAGGAAATGTTACA
TAATATAGTTAATGTAATAAAGGAAAATACTCAAAATAACTTTGAGATAATATACACCTTAGATGAGGAGCTTATTTTAA
TAAATTCTTGGGATGAAGCCTTAAGTAAAAAAGAGATTAAAAAATATTATGATAAGTTAAAAGAACAAATAATAAATGAA
TATGGAATAGATGTATTTTTAAGTGTTGGAGAACCTGTTTGTGATCTTTATAAAATTAGTTCAAGTTATAAGGAAGCAAA
TAATTTAAAAAAATATGTTCTTACCTTAGGATATAATAAGTGTATAACAACAGAGGATGTTAAGGATATAAATGAGAAAA
ATATAAACTTTAGTGAGGTTTTAGATAAATTAAATAAAAGAATAATTGCTAAAGATATAGAAGGGGCAGAAAAAATCATT
GAGGAAACTGTTGAGGATAAAAAGTTAAATCCAAGAAATATATATGATTTATCTGTAAAAATACTATTTTTATTAGATGG
TATTGTGGAAGAATTTAAAGTTGAAAAACAATATACAGGAAATAGTTTAGGAGAGGAAATCGTTGCTCTTTGTAGTGAAG
ATACAAGGGAAGATATTAAAACCTTATTATGTAGTGAAATCAGGGAAGTTATAGAACTTATGCACCCAACAACCATAAAA
TATAGCCCTGTAATTCAACAAATAATAAGTTATGTAAATGAAAACTATTATGAAGAGGTAAGCCTTAAGACCTTAGCTCA
AAAATATCATATAAATACTTCTTATTTAGGTCAAGTATTTACTAAAGAAGTTGGATGTTCATTTTCTGAGTATTTAAATA
AAACCAAAAATATGAAAGCTAAAGAGCTTATATTAAATACAAATATGAAGATAAATGATATAGCTAAAAAAGTAGGGTAT
TTAGATACTAGTTATTTCTATAGAAAGTTTAAAAAGTACTATGGAGTTTGTCCATCAACCTTAAGAAATATAAAAAATTA
CTAA

Upstream 100 bases:

>100_bases
ATTAAATATGGGGAACCTTATGGGTTAACTGTTACTAGTGAGGAGAATAAGGGAACTAATATGATTTTAAAATTCCCGCT
TAGAGAGGTGGAGTAGTAAT

Downstream 100 bases:

>100_bases
TTATAAAGCTTGAGAATATTAAGCTGTATTCAAAAATAAATTTTGAGTACAGCTTTTTTTATGAAACTTTGTTAAAAAAA
TAATATTTAAAACAAGAATT

Product: DNA-binding response regulator, AraC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQVTGLELLKELKKINSDVKFI
ILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTINKIKQEKEENKSSLGKHNILIKLIKGKLAQGEIEENKEGF
YMNLNSERYSLCIINTRSRYDSEEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKYYDKLKEQIINE
YGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVLTLGYNKCITTEDVKDINEKNINFSEVLDKLNKRIIAKDIEGAEKII
EETVEDKKLNPRNIYDLSVKILFLLDGIVEEFKVEKQYTGNSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTIK
YSPVIQQIISYVNENYYEEVSLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGY
LDTSYFYRKFKKYYGVCPSTLRNIKNY

Sequences:

>Translated_507_residues
MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQVTGLELLKELKKINSDVKFI
ILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTINKIKQEKEENKSSLGKHNILIKLIKGKLAQGEIEENKEGF
YMNLNSERYSLCIINTRSRYDSEEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKYYDKLKEQIINE
YGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVLTLGYNKCITTEDVKDINEKNINFSEVLDKLNKRIIAKDIEGAEKII
EETVEDKKLNPRNIYDLSVKILFLLDGIVEEFKVEKQYTGNSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTIK
YSPVIQQIISYVNENYYEEVSLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGY
LDTSYFYRKFKKYYGVCPSTLRNIKNY
>Mature_507_residues
MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQVTGLELLKELKKINSDVKFI
ILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTINKIKQEKEENKSSLGKHNILIKLIKGKLAQGEIEENKEGF
YMNLNSERYSLCIINTRSRYDSEEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKYYDKLKEQIINE
YGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVLTLGYNKCITTEDVKDINEKNINFSEVLDKLNKRIIAKDIEGAEKII
EETVEDKKLNPRNIYDLSVKILFLLDGIVEEFKVEKQYTGNSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTIK
YSPVIQQIISYVNENYYEEVSLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGY
LDTSYFYRKFKKYYGVCPSTLRNIKNY

Specific function: Member of the two-component regulatory system yesM/yesN [H]

COG id: COG4753

COG function: function code T; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=138, Percent_Identity=35.5072463768116, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788222, Length=190, Percent_Identity=26.8421052631579, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790391, Length=121, Percent_Identity=29.7520661157025, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788521, Length=116, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790437, Length=90, Percent_Identity=30, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786747, Length=141, Percent_Identity=28.3687943262411, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=26.984126984127, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00165 HTH_AraC; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 58844; Mature: 58844

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCC
VTGLELLKELKKINSDVKFIILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTI
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NKIKQEKEENKSSLGKHNILIKLIKGKLAQGEIEENKEGFYMNLNSERYSLCIINTRSRY
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCC
DSEEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKYYDKLKEQIINE
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVLTLGYNKCITTEDVKDINEKNINFSEV
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHH
LDKLNKRIIAKDIEGAEKIIEETVEDKKLNPRNIYDLSVKILFLLDGIVEEFKVEKQYTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTIKYSPVIQQIISYVNENYYEEV
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHH
SLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGY
HHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCC
LDTSYFYRKFKKYYGVCPSTLRNIKNY
CCHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MYKVMLADDENLILQGLENIIEWEELGLEIVNKASNGQEAIDKFKENPVDIVVTDINMPQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCC
VTGLELLKELKKINSDVKFIILSGYDDFSYAKKAIELGVENYILKPIDEEELEKTLKNTI
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NKIKQEKEENKSSLGKHNILIKLIKGKLAQGEIEENKEGFYMNLNSERYSLCIINTRSRY
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCC
DSEEMLHNIVNVIKENTQNNFEIIYTLDEELILINSWDEALSKKEIKKYYDKLKEQIINE
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YGIDVFLSVGEPVCDLYKISSSYKEANNLKKYVLTLGYNKCITTEDVKDINEKNINFSEV
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHH
LDKLNKRIIAKDIEGAEKIIEETVEDKKLNPRNIYDLSVKILFLLDGIVEEFKVEKQYTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NSLGEEIVALCSEDTREDIKTLLCSEIREVIELMHPTTIKYSPVIQQIISYVNENYYEEV
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHH
SLKTLAQKYHINTSYLGQVFTKEVGCSFSEYLNKTKNMKAKELILNTNMKINDIAKKVGY
HHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCC
LDTSYFYRKFKKYYGVCPSTLRNIKNY
CCHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]