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The map label for this gene is moaB [H]

Identifier: 18311068

GI number: 18311068

Start: 2392828

End: 2393319

Strand: Reverse

Name: moaB [H]

Synonym: CPE2086

Alternate gene names: 18311068

Gene position: 2393319-2392828 (Counterclockwise)

Preceding gene: 18311069

Following gene: 18311067

Centisome position: 78.95

GC content: 32.32

Gene sequence:

>492_bases
ATGTATAAATTAGGAATAATAACTAGCAGTGATAAAGGATATTCAGGAGAAAGAAAGGATGAAAGTGGATTAGTAATAGC
TGATATTGCAAAGGGAAAAGGATTTAAGGTAGAAAAGTATATAGTTTTACCAGATGAAAGAGAAATGCTTAGAGATGAGA
TGATTAATATGGCTGATAACTTAGGTGTTGATCTTATACTTACAACTGGTGGTACTGGATTTAGTAAAAGAGATGTTACT
CCAGAGGCAACTAAGGATGTTATAGAAAAGGAAGCATTAGGAATACCAGAAGCTATAAGAAGTTATAGTATGACAATAAC
TAAAAGAGCTATGCTTTCTAGAGCTACTGCAGGTATAAGAAAAGATACTCTTATTGTTAATATGCCTGGTAGTCCAAAAG
CTTGTAGAGAAGTTATGGACTATATTTTAGATGATTTAAAACATGGAATAGATATTATGAAGGGAGATGCTAGAGAATGC
GCAAGAAAATAA

Upstream 100 bases:

>100_bases
TTATTTTAGGTAAATGTTGATTTCTAGCTATATATTTAGAAATCAACAATAGTTTAATATAGACTTTTTTATTAAAATTA
AAAGGTAGGTGCTTTAGAGT

Downstream 100 bases:

>100_bases
GCCTATCTATAATAATGGCAATAGGAATGTTATCATTATTATTTGTAGGATGCACTAATAATAAGGAAGAGAAAACTTTA
ACAGTTAGCATTGCTGCAAG

Product: molybdenum cofactor synthesis protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MYKLGIITSSDKGYSGERKDESGLVIADIAKGKGFKVEKYIVLPDEREMLRDEMINMADNLGVDLILTTGGTGFSKRDVT
PEATKDVIEKEALGIPEAIRSYSMTITKRAMLSRATAGIRKDTLIVNMPGSPKACREVMDYILDDLKHGIDIMKGDAREC
ARK

Sequences:

>Translated_163_residues
MYKLGIITSSDKGYSGERKDESGLVIADIAKGKGFKVEKYIVLPDEREMLRDEMINMADNLGVDLILTTGGTGFSKRDVT
PEATKDVIEKEALGIPEAIRSYSMTITKRAMLSRATAGIRKDTLIVNMPGSPKACREVMDYILDDLKHGIDIMKGDAREC
ARK
>Mature_163_residues
MYKLGIITSSDKGYSGERKDESGLVIADIAKGKGFKVEKYIVLPDEREMLRDEMINMADNLGVDLILTTGGTGFSKRDVT
PEATKDVIEKEALGIPEAIRSYSMTITKRAMLSRATAGIRKDTLIVNMPGSPKACREVMDYILDDLKHGIDIMKGDAREC
ARK

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=155, Percent_Identity=42.5806451612903, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI66932975, Length=155, Percent_Identity=42.5806451612903, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1786190, Length=155, Percent_Identity=34.1935483870968, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1787000, Length=142, Percent_Identity=33.8028169014084, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17564954, Length=173, Percent_Identity=41.6184971098266, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136978, Length=162, Percent_Identity=38.2716049382716, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24638841, Length=162, Percent_Identity=38.2716049382716, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17990; Mature: 17990

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLGIITSSDKGYSGERKDESGLVIADIAKGKGFKVEKYIVLPDEREMLRDEMINMADN
CEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHC
LGVDLILTTGGTGFSKRDVTPEATKDVIEKEALGIPEAIRSYSMTITKRAMLSRATAGIR
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KDTLIVNMPGSPKACREVMDYILDDLKHGIDIMKGDARECARK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MYKLGIITSSDKGYSGERKDESGLVIADIAKGKGFKVEKYIVLPDEREMLRDEMINMADN
CEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHC
LGVDLILTTGGTGFSKRDVTPEATKDVIEKEALGIPEAIRSYSMTITKRAMLSRATAGIR
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
KDTLIVNMPGSPKACREVMDYILDDLKHGIDIMKGDARECARK
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]