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The map label for this gene is yicI [C]

Identifier: 18311058

GI number: 18311058

Start: 2379557

End: 2381797

Strand: Reverse

Name: yicI [C]

Synonym: CPE2076

Alternate gene names: 18311058

Gene position: 2381797-2379557 (Counterclockwise)

Preceding gene: 18311059

Following gene: 18311057

Centisome position: 78.57

GC content: 30.03

Gene sequence:

>2241_bases
ATGGCGCAATTAAATTACAGAGAGAATTTAAATATGAAATTTAAAGCTTATAATGGTGGATTAAGAGTTTTTAAAAATTA
TGAGATTAATCATAATAATATAGATATTTATTTTTCAAATATGAAAATAACTCTTACTATGTTTGAAAATGATATAGTTA
AAGTTTTTATTGGAGATAAATATGAAGAAAGTATTTCAACTAATGGTGTAGTAGATGATTTAGGAAAAGGTGAATTTATA
GTAGAAGAGGATTCAAACTTTGTAATTGTAAAGGGCACTAAAGTTTTAACCTTTGTAGATAAAAATACTACAGAGATAAG
TTTTAGAGATTTAGAAGGAAATATAATAAATGAAGATTTTCAGCCAAGCTTTAAGGATGAAGAAGGAAATGTGTACATAT
CAAAGGTAAATGATTGTTTAGCATATTATGGACTTGGAGAAAAGGGTGGAGATTTAAATAAAAAAGGATGTTATACAGAA
AACTTTAATACTGATGATCCAGAGACTGACGATGATTCCATAACTTATTATAAGACAATTCCTTTTTATGTTGCCTTAAA
AGAAGAAGCTACCTATGGAATATTCTTTGATAATAGCTTTAGAAGTTATTTTGATATGGGAAAGGAAATGGGAGATAGGA
TTTTCTTTGGAGCCATCGGAGGACAAATTCAATATTACTTTATTCCAGGAGAAAATATTAAAGAGGTAGTTAAGAATTAT
ACTGCTTTAACAGGGAGAATGGAGATGCCACCTCTTTGGAGCTTAGGATATCAACAATGTAGATTTAGTTATTTTAGCCA
AGAGGAAGTAAGAGAGTTAGTAAAAACCTTTGAAGAAAAAGATATTCCCTTAGATGTAGTTTATTTAGATATAGATTACA
TGGATGGATTTAGAGTTATGACTTTTAAAACTCCTAATTTTCATGATGCAGCTGGTCTTATTAGTGATTTAAAAGAAAAG
GGAATAAGAACTATTACTATTATTGACCCAGGTGTTAAGGTAGATGAAGAGTACCATGTATTTAAAAGAGGTAAAGAAGG
GAATCATTTTACTAAAAAGCTAGATGGAGAAATGTTTATTGGGGCAGTTTGGCCAGGTGATAGTGCTTTCCCTGATTTTT
CAAATAAGGATTGTAGGGAATGGTGGAAAAGTGAACTTAAAAAATTCATAAGTGAGCATGGCATGGATGGAATTTGGAAT
GATATGAATGAACCTTGTGTCTTTAATAATGATCATAAAACAATGTTAGAAACCTGCCTTCATAATAGTGATAATGGAGT
TATAGAACATAAGGAATTTCATAATAGATATGGCTTTGAAATGAGCAGATGTTCTAAGGAAGCGCAAGAAGAATTACATC
CTAATGAAAGAGGATTTTCAATGACTAGAGCTACCTATGCTGGGGGTCAAAGATATTCCTCAGTTTGGACTGGAGATAAT
ATGAGCCTTTGGAGCCAAATGAGAATGTCAATATCAATGAATGCTAATTTAGGAATCAGTGGATTTTCCTTTGTTGGAAA
TGATGTTTCAGGTTTTGGATTAGATTCAAGTGAAGAATTATTTATAAGATGGATGGAAATGGGGCCATTTATTCCTATAT
TCAGAAATCACTCAAATATGTACACTAGAAGACAAGAACCATGGGCTTTTGGACCAAGAGCTGAAAAAATAGCAAAGAAA
TCTATTGAGTTAAGATATGAGTTACTTCCATATATTTATGATTTATATTATATATCACATAAAGAAGGACTTCCTATATT
TAGACCTATGATAATGGAATATGAGAAAGATATGAATCTTTTAAATATGAGAGAACAATTTATGTTAGGTGAAAATATGC
TTGTTGCACCAGTATTATATGAAGGGGAAAGAAGCAAAACTGTATATTTACCAAAGGGAAGTTGGTTTAATTATTTTACA
ATGGAGAAGTTACAAGGAGGAAAGTGGTATAAGCTTCCTTGTGAATTAGATGAAATTTTAGTTTTTGTTAAAGAAGGAGC
AATAATACCAACATATAATAAGAAATTTAGAAATGTTAAAGAAAGACCAAATAATATACTTCTTAAGGTTTTTGGAGAGA
ATGCTAAAGGATTCCACTATAATGATGATGGACATACTATGGAATATTTAGAGGGAAAATATACTTATATGGACATAAAA
GTTGTAGATGGAAAAGAAGAACTTAAGCTTATTAATAATGGAGATAGTATAGAGGAGATTGAATTTGAAATAATAAAATA
A

Upstream 100 bases:

>100_bases
TGATTCAAATTTAATAGGAGCATTATATAACTTTCTTTTTGTTAGAAAATAAATCTTATTATTTCAAGAAAAATCATATA
GATAAAAAGGGGAAAATGTT

Downstream 100 bases:

>100_bases
TCTATAATAAATTATTTTTATATATACTCATGTTTATTTAGATAATAGGCATGAGTATTAATTTTTATTTTTTTTGATAA
AATTATTTTAATGTTAACAT

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MAQLNYRENLNMKFKAYNGGLRVFKNYEINHNNIDIYFSNMKITLTMFENDIVKVFIGDKYEESISTNGVVDDLGKGEFI
VEEDSNFVIVKGTKVLTFVDKNTTEISFRDLEGNIINEDFQPSFKDEEGNVYISKVNDCLAYYGLGEKGGDLNKKGCYTE
NFNTDDPETDDDSITYYKTIPFYVALKEEATYGIFFDNSFRSYFDMGKEMGDRIFFGAIGGQIQYYFIPGENIKEVVKNY
TALTGRMEMPPLWSLGYQQCRFSYFSQEEVRELVKTFEEKDIPLDVVYLDIDYMDGFRVMTFKTPNFHDAAGLISDLKEK
GIRTITIIDPGVKVDEEYHVFKRGKEGNHFTKKLDGEMFIGAVWPGDSAFPDFSNKDCREWWKSELKKFISEHGMDGIWN
DMNEPCVFNNDHKTMLETCLHNSDNGVIEHKEFHNRYGFEMSRCSKEAQEELHPNERGFSMTRATYAGGQRYSSVWTGDN
MSLWSQMRMSISMNANLGISGFSFVGNDVSGFGLDSSEELFIRWMEMGPFIPIFRNHSNMYTRRQEPWAFGPRAEKIAKK
SIELRYELLPYIYDLYYISHKEGLPIFRPMIMEYEKDMNLLNMREQFMLGENMLVAPVLYEGERSKTVYLPKGSWFNYFT
MEKLQGGKWYKLPCELDEILVFVKEGAIIPTYNKKFRNVKERPNNILLKVFGENAKGFHYNDDGHTMEYLEGKYTYMDIK
VVDGKEELKLINNGDSIEEIEFEIIK

Sequences:

>Translated_746_residues
MAQLNYRENLNMKFKAYNGGLRVFKNYEINHNNIDIYFSNMKITLTMFENDIVKVFIGDKYEESISTNGVVDDLGKGEFI
VEEDSNFVIVKGTKVLTFVDKNTTEISFRDLEGNIINEDFQPSFKDEEGNVYISKVNDCLAYYGLGEKGGDLNKKGCYTE
NFNTDDPETDDDSITYYKTIPFYVALKEEATYGIFFDNSFRSYFDMGKEMGDRIFFGAIGGQIQYYFIPGENIKEVVKNY
TALTGRMEMPPLWSLGYQQCRFSYFSQEEVRELVKTFEEKDIPLDVVYLDIDYMDGFRVMTFKTPNFHDAAGLISDLKEK
GIRTITIIDPGVKVDEEYHVFKRGKEGNHFTKKLDGEMFIGAVWPGDSAFPDFSNKDCREWWKSELKKFISEHGMDGIWN
DMNEPCVFNNDHKTMLETCLHNSDNGVIEHKEFHNRYGFEMSRCSKEAQEELHPNERGFSMTRATYAGGQRYSSVWTGDN
MSLWSQMRMSISMNANLGISGFSFVGNDVSGFGLDSSEELFIRWMEMGPFIPIFRNHSNMYTRRQEPWAFGPRAEKIAKK
SIELRYELLPYIYDLYYISHKEGLPIFRPMIMEYEKDMNLLNMREQFMLGENMLVAPVLYEGERSKTVYLPKGSWFNYFT
MEKLQGGKWYKLPCELDEILVFVKEGAIIPTYNKKFRNVKERPNNILLKVFGENAKGFHYNDDGHTMEYLEGKYTYMDIK
VVDGKEELKLINNGDSIEEIEFEIIK
>Mature_745_residues
AQLNYRENLNMKFKAYNGGLRVFKNYEINHNNIDIYFSNMKITLTMFENDIVKVFIGDKYEESISTNGVVDDLGKGEFIV
EEDSNFVIVKGTKVLTFVDKNTTEISFRDLEGNIINEDFQPSFKDEEGNVYISKVNDCLAYYGLGEKGGDLNKKGCYTEN
FNTDDPETDDDSITYYKTIPFYVALKEEATYGIFFDNSFRSYFDMGKEMGDRIFFGAIGGQIQYYFIPGENIKEVVKNYT
ALTGRMEMPPLWSLGYQQCRFSYFSQEEVRELVKTFEEKDIPLDVVYLDIDYMDGFRVMTFKTPNFHDAAGLISDLKEKG
IRTITIIDPGVKVDEEYHVFKRGKEGNHFTKKLDGEMFIGAVWPGDSAFPDFSNKDCREWWKSELKKFISEHGMDGIWND
MNEPCVFNNDHKTMLETCLHNSDNGVIEHKEFHNRYGFEMSRCSKEAQEELHPNERGFSMTRATYAGGQRYSSVWTGDNM
SLWSQMRMSISMNANLGISGFSFVGNDVSGFGLDSSEELFIRWMEMGPFIPIFRNHSNMYTRRQEPWAFGPRAEKIAKKS
IELRYELLPYIYDLYYISHKEGLPIFRPMIMEYEKDMNLLNMREQFMLGENMLVAPVLYEGERSKTVYLPKGSWFNYFTM
EKLQGGKWYKLPCELDEILVFVKEGAIIPTYNKKFRNVKERPNNILLKVFGENAKGFHYNDDGHTMEYLEGKYTYMDIKV
VDGKEELKLINNGDSIEEIEFEIIK

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=571, Percent_Identity=34.5008756567426, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI88900491, Length=567, Percent_Identity=32.8042328042328, Blast_Score=354, Evalue=2e-97,
Organism=Homo sapiens, GI38202257, Length=567, Percent_Identity=32.8042328042328, Blast_Score=353, Evalue=3e-97,
Organism=Homo sapiens, GI119393895, Length=662, Percent_Identity=31.1178247734139, Blast_Score=325, Evalue=1e-88,
Organism=Homo sapiens, GI119393893, Length=662, Percent_Identity=31.1178247734139, Blast_Score=325, Evalue=1e-88,
Organism=Homo sapiens, GI119393891, Length=662, Percent_Identity=31.1178247734139, Blast_Score=325, Evalue=1e-88,
Organism=Homo sapiens, GI221316699, Length=631, Percent_Identity=29.7939778129952, Blast_Score=308, Evalue=9e-84,
Organism=Homo sapiens, GI310115361, Length=525, Percent_Identity=33.5238095238095, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI157364974, Length=651, Percent_Identity=29.0322580645161, Blast_Score=283, Evalue=5e-76,
Organism=Homo sapiens, GI153791946, Length=446, Percent_Identity=22.8699551569507, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI2367256, Length=603, Percent_Identity=25.0414593698176, Blast_Score=215, Evalue=1e-56,
Organism=Escherichia coli, GI2367323, Length=446, Percent_Identity=25.7847533632287, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71991189, Length=574, Percent_Identity=32.9268292682927, Blast_Score=343, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17560798, Length=583, Percent_Identity=31.2178387650086, Blast_Score=341, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17560800, Length=583, Percent_Identity=31.2178387650086, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI32563849, Length=631, Percent_Identity=27.5752773375594, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71985706, Length=585, Percent_Identity=27.8632478632479, Blast_Score=244, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6319706, Length=559, Percent_Identity=30.9481216457961, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24643749, Length=579, Percent_Identity=29.1882556131261, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24643753, Length=579, Percent_Identity=29.1882556131261, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24643751, Length=579, Percent_Identity=29.1882556131261, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24643746, Length=579, Percent_Identity=29.1882556131261, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI21357605, Length=579, Percent_Identity=29.1882556131261, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24650054, Length=433, Percent_Identity=24.7113163972286, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571438, Length=402, Percent_Identity=22.3880597014925, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571440, Length=395, Percent_Identity=22.0253164556962, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 86908; Mature: 86777

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLNYRENLNMKFKAYNGGLRVFKNYEINHNNIDIYFSNMKITLTMFENDIVKVFIGDK
CCCCCCCCCCCEEEEEECCCEEEEEEEEECCCEEEEEEECEEEEEEEECCCEEEEEECCC
YEESISTNGVVDDLGKGEFIVEEDSNFVIVKGTKVLTFVDKNTTEISFRDLEGNIINEDF
HHHHCCCCCCHHCCCCCCEEEECCCCEEEEECCEEEEEEECCCCEEEEEECCCCEECCCC
QPSFKDEEGNVYISKVNDCLAYYGLGEKGGDLNKKGCYTENFNTDDPETDDDSITYYKTI
CCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEE
PFYVALKEEATYGIFFDNSFRSYFDMGKEMGDRIFFGAIGGQIQYYFIPGENIKEVVKNY
EEEEEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEECCEEEEEEECCCCHHHHHHHH
TALTGRMEMPPLWSLGYQQCRFSYFSQEEVRELVKTFEEKDIPLDVVYLDIDYMDGFRVM
HHHCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEE
TFKTPNFHDAAGLISDLKEKGIRTITIIDPGVKVDEEYHVFKRGKEGNHFTKKLDGEMFI
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCEEE
GAVWPGDSAFPDFSNKDCREWWKSELKKFISEHGMDGIWNDMNEPCVFNNDHKTMLETCL
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEECCHHHHHHHHH
HNSDNGVIEHKEFHNRYGFEMSRCSKEAQEELHPNERGFSMTRATYAGGQRYSSVWTGDN
CCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECEEECCCC
MSLWSQMRMSISMNANLGISGFSFVGNDVSGFGLDSSEELFIRWMEMGPFIPIFRNHSNM
HHHHHHEEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHEEEEECCCCCCEEEECCCCC
YTRRQEPWAFGPRAEKIAKKSIELRYELLPYIYDLYYISHKEGLPIFRPMIMEYEKDMNL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCHH
LNMREQFMLGENMLVAPVLYEGERSKTVYLPKGSWFNYFTMEKLQGGKWYKLPCELDEIL
HHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCCCEEEHHHCCCCCEEECCCCHHHEE
VFVKEGAIIPTYNKKFRNVKERPNNILLKVFGENAKGFHYNDDGHTMEYLEGKYTYMDIK
EEEECCCEECCCCHHHHHHHCCCCEEEEEEECCCCCCCEECCCCCEEHHCCCEEEEEEEE
VVDGKEELKLINNGDSIEEIEFEIIK
EECCHHHEEEECCCCCCEEEEEEEEC
>Mature Secondary Structure 
AQLNYRENLNMKFKAYNGGLRVFKNYEINHNNIDIYFSNMKITLTMFENDIVKVFIGDK
CCCCCCCCCCEEEEEECCCEEEEEEEEECCCEEEEEEECEEEEEEEECCCEEEEEECCC
YEESISTNGVVDDLGKGEFIVEEDSNFVIVKGTKVLTFVDKNTTEISFRDLEGNIINEDF
HHHHCCCCCCHHCCCCCCEEEECCCCEEEEECCEEEEEEECCCCEEEEEECCCCEECCCC
QPSFKDEEGNVYISKVNDCLAYYGLGEKGGDLNKKGCYTENFNTDDPETDDDSITYYKTI
CCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEE
PFYVALKEEATYGIFFDNSFRSYFDMGKEMGDRIFFGAIGGQIQYYFIPGENIKEVVKNY
EEEEEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEECCEEEEEEECCCCHHHHHHHH
TALTGRMEMPPLWSLGYQQCRFSYFSQEEVRELVKTFEEKDIPLDVVYLDIDYMDGFRVM
HHHCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEE
TFKTPNFHDAAGLISDLKEKGIRTITIIDPGVKVDEEYHVFKRGKEGNHFTKKLDGEMFI
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCHHHHCCCCCEEE
GAVWPGDSAFPDFSNKDCREWWKSELKKFISEHGMDGIWNDMNEPCVFNNDHKTMLETCL
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCEEEECCHHHHHHHHH
HNSDNGVIEHKEFHNRYGFEMSRCSKEAQEELHPNERGFSMTRATYAGGQRYSSVWTGDN
CCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECEEECCCC
MSLWSQMRMSISMNANLGISGFSFVGNDVSGFGLDSSEELFIRWMEMGPFIPIFRNHSNM
HHHHHHEEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHEEEEECCCCCCEEEECCCCC
YTRRQEPWAFGPRAEKIAKKSIELRYELLPYIYDLYYISHKEGLPIFRPMIMEYEKDMNL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCHH
LNMREQFMLGENMLVAPVLYEGERSKTVYLPKGSWFNYFTMEKLQGGKWYKLPCELDEIL
HHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCCCEEEHHHCCCCCEEECCCCHHHEE
VFVKEGAIIPTYNKKFRNVKERPNNILLKVFGENAKGFHYNDDGHTMEYLEGKYTYMDIK
EEEECCCEECCCCHHHHHHHCCCCEEEEEEECCCCCCCEECCCCCEEHHCCCEEEEEEEE
VVDGKEELKLINNGDSIEEIEFEIIK
EECCHHHEEEECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]