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The map label for this gene is murG

Identifier: 18311045

GI number: 18311045

Start: 2360400

End: 2361473

Strand: Reverse

Name: murG

Synonym: CPE2063

Alternate gene names: 18311045

Gene position: 2361473-2360400 (Counterclockwise)

Preceding gene: 18311047

Following gene: 18311044

Centisome position: 77.9

GC content: 27.75

Gene sequence:

>1074_bases
TTGAAAAAGTATAAAATAATTATGACTGGTGGAGGTTCAGCAGGTCATGTTACCCCAAATTTAGCTTTAGTTCCTAAATT
AAAAGAGTTAGGTTTTGAAATAAAATATATAGGAAGTAAAAATGGTATAGAAAAAGAAATAATAACTAAGGAGAATATAC
CTTATTATTCAATATCATCAGGTAAGCTCAGAAGATATTTTGATATAAAAAACTTTACAGATCCTTTTAAAGTATTAAAA
GGTGTTATGGATGCCTCAAGAATACTTTCAAAAGAAAAACCAGATGTTATATTTTCAAAGGGTGGCTTTGTTACAGTACC
TGTAGTAATAGCAGCCTCAATGAAAAAAATTCCTGTGGTATCTCATGAATCAGATTTAACCCCTGGATTAGCAAATAAAA
TAGCATCACCATTTTGTGATACACTTTGTGTTACATTCCCAGAAAGTTTAAAATATATAAAAGATAATAAAGGTGAATTA
ACAGGAACTCCAATAAGAGAAGACCTTTTAAAGGGAGACAAAGAAAGAGGAAGAAAGTTCTGTAACTTCAAAGAAAATAA
AAAAGTTCTTATGATAATTGGTGGTAGTTTAGGTTCAAAAGTTATAAATGAAAGCGTTAGAAAGATTTTAAATGAGATAT
TAAAAGAATATAATGTTATACATTTATGTGGAAAAGGAAACTTAGATGAATCATTAAAGAACTTAGATGGATATAGACAA
TATGAGTATATATCAGAGGAACTTCCAGATTTAATGGCTTTAGCAGATTTAGTTATTTCTAGAGCAGGAGCAAATACAAT
ATTTGAATTATTAGCTCTTAGAAAGTTAAATATATTAATACCTTTATCAGCTAATGCTTCAAGAGGAGATCAAGTTTTAA
ATGCTAATTCCTTTGAAAAGAGTGGATATTCTATGGTCATAAAAGAAGAAGAGCTTAATTCAGAATTATTATTAAAATCA
ATAAAGGATTTAGAAAAAAATAGAGAAAAGTACTTAAATTCCATGAAAATGAGCAAAATAGGCAATGGTGTTAATAATAT
CATAGATATAATAAAAAAATCGGCACATATGTAA

Upstream 100 bases:

>100_bases
TATGAGAGGGAATTATAGGAGTTATTACAAAAAAATATTTATAAAACCATAGTTTATTTAAAATATTATAAAATCACATT
TTATTAAGGGAGTTGATTTT

Downstream 100 bases:

>100_bases
ATTTTTATAGATAATTCTTAGCATATAGTAGAAGTTTTACAAGAATTAAGAATAAACTATGAAAATATGTTTCAAAATAT
CGGAATATGAAACTTGAAAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISSGKLRRYFDIKNFTDPFKVLK
GVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVVSHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGEL
TGTPIREDLLKGDKERGRKFCNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQ
YEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEKSGYSMVIKEEELNSELLLKS
IKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM

Sequences:

>Translated_357_residues
MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISSGKLRRYFDIKNFTDPFKVLK
GVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVVSHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGEL
TGTPIREDLLKGDKERGRKFCNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQ
YEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEKSGYSMVIKEEELNSELLLKS
IKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM
>Mature_357_residues
MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISSGKLRRYFDIKNFTDPFKVLK
GVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVVSHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGEL
TGTPIREDLLKGDKERGRKFCNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQ
YEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEKSGYSMVIKEEELNSELLLKS
IKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=340, Percent_Identity=25.2941176470588, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CLOP1 (Q0TNP7)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696743.2
- ProteinModelPortal:   Q0TNP7
- SMR:   Q0TNP7
- STRING:   Q0TNP7
- GeneID:   4203621
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2320
- TIGR:   CPF_2320
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- ProtClustDB:   PRK00726
- BioCyc:   CPER195103:CPF_2320-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39786; Mature: 39786

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISS
CCCEEEEEECCCCCCCCCCCCEECCCHHHCCCEEEEECCCCCCCHHHHCCCCCCEEEECC
GKLRRYFDIKNFTDPFKVLKGVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHCCCEE
SHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGELTGTPIREDLLKGDKERGRKF
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHCHHH
CNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQ
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHHHH
YEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCCCCEECCCCCCC
SGYSMVIKEEELNSELLLKSIKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM
CCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISS
CCCEEEEEECCCCCCCCCCCCEECCCHHHCCCEEEEECCCCCCCHHHHCCCCCCEEEECC
GKLRRYFDIKNFTDPFKVLKGVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVV
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHCCCEE
SHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGELTGTPIREDLLKGDKERGRKF
CCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHCHHH
CNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQ
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHHHH
YEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCCCCEECCCCCCC
SGYSMVIKEEELNSELLLKSIKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM
CCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA