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The map label for this gene is holA [H]

Identifier: 18311025

GI number: 18311025

Start: 2334511

End: 2335557

Strand: Reverse

Name: holA [H]

Synonym: CPE2043

Alternate gene names: 18311025

Gene position: 2335557-2334511 (Counterclockwise)

Preceding gene: 18311026

Following gene: 18311023

Centisome position: 77.04

GC content: 25.69

Gene sequence:

>1047_bases
ATGATAGATTTAGACGGTTTATATGAAAATTTGAAAAAAGGAAAGATAGAAAAAAGTTATATATTAGTTGGATTAGATGA
GCTTTTAATTAAAGAAGGTATAGAAAATATAATTGATAATGTATTAGATGAAGGATTTAAGGATTTAAACCTAATTAGAT
TAGATGGGAATAACCTTAATTTTGATGATTTCATGAATGCTTGTGAAACATTGCCTTTTATGAGTGATAAAAAAGTAGTA
GTTTTAAATAGAACTAATATATTTAGGGATAAACAAGATAAAGAAACTGAAAAATTATATAAGCAATGTATAGAATATTT
TCAAAATACACCAGAACATTGTGTTTTAATAGCATATACAACTTTAAAGGATAAAAGGGATAGAGTTAATAGATTAAGCA
AACTAAAAAAGCTTGAGAAGAGTAGTTGTATAGTTTCTGTTGAAAAGCTAAAAGGGGCAAAACTACAACAAAAAGTAGGT
AGAATCTTTCAAAGATATAATAAAAATATAGGAAAAATAGAGTTAAAATACTTTTGTGACTCAGTAGAAAATAACTTTGA
TGTTATAGAAAGAGAAGTTGATAAAATAGTAAACTATGTTGGGGAGAGAGAAATAACTAGAAAAGACATAGATCTACTAC
TTCCTCCTAGGTATGAGGACGATATATTTGATTTAGTTGAGCTTATTTCAATTAAAAGAGCAAAGCAAGCCATAGACTTA
ATGGATGAATTAATAGGCAGAGGACAAGATCCCATATTTATACTAAGTCAAATCAGAGAGCAATTTCAAAAGTTACACAG
GGTTAAAATAAGACTTTCTGAAAAGTATAGAATTGATGAAATAAAGAAAGATTTTTTAGAATTTAGTAGAGTAAATTTAC
CTGACTTTGTAATAGAAAAATTTATTAATCAGAGTAAGAAGTTTTCTAATAAACAGCTTAATAAATGTATTAATCTATGT
TTATATACAGAAAAGAAACTTAAGAGTAATTCAAACTTAAATAAAAAAACAGAGTTAGAACTTATGATAGTGAGTACTGT
AATATAA

Upstream 100 bases:

>100_bases
AATAGTGATTATGATATAATTGATTTGATTCAAAAGAAAAGTGCGTATATACTTTAACTTATGTAAATAAGTAGCTGGGA
TTTGAAAGGTTGATATTTTA

Downstream 100 bases:

>100_bases
AAAATCCAGATTAGATGATTCTAATCTGGATTTTTTACTTAAAGAAATACTTCTAATAAAAGAAAATGGTGTTAGAAATT
CTAACACCCATATAATTAAG

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIDLDGLYENLKKGKIEKSYILVGLDELLIKEGIENIIDNVLDEGFKDLNLIRLDGNNLNFDDFMNACETLPFMSDKKVV
VLNRTNIFRDKQDKETEKLYKQCIEYFQNTPEHCVLIAYTTLKDKRDRVNRLSKLKKLEKSSCIVSVEKLKGAKLQQKVG
RIFQRYNKNIGKIELKYFCDSVENNFDVIEREVDKIVNYVGEREITRKDIDLLLPPRYEDDIFDLVELISIKRAKQAIDL
MDELIGRGQDPIFILSQIREQFQKLHRVKIRLSEKYRIDEIKKDFLEFSRVNLPDFVIEKFINQSKKFSNKQLNKCINLC
LYTEKKLKSNSNLNKKTELELMIVSTVI

Sequences:

>Translated_348_residues
MIDLDGLYENLKKGKIEKSYILVGLDELLIKEGIENIIDNVLDEGFKDLNLIRLDGNNLNFDDFMNACETLPFMSDKKVV
VLNRTNIFRDKQDKETEKLYKQCIEYFQNTPEHCVLIAYTTLKDKRDRVNRLSKLKKLEKSSCIVSVEKLKGAKLQQKVG
RIFQRYNKNIGKIELKYFCDSVENNFDVIEREVDKIVNYVGEREITRKDIDLLLPPRYEDDIFDLVELISIKRAKQAIDL
MDELIGRGQDPIFILSQIREQFQKLHRVKIRLSEKYRIDEIKKDFLEFSRVNLPDFVIEKFINQSKKFSNKQLNKCINLC
LYTEKKLKSNSNLNKKTELELMIVSTVI
>Mature_348_residues
MIDLDGLYENLKKGKIEKSYILVGLDELLIKEGIENIIDNVLDEGFKDLNLIRLDGNNLNFDDFMNACETLPFMSDKKVV
VLNRTNIFRDKQDKETEKLYKQCIEYFQNTPEHCVLIAYTTLKDKRDRVNRLSKLKKLEKSSCIVSVEKLKGAKLQQKVG
RIFQRYNKNIGKIELKYFCDSVENNFDVIEREVDKIVNYVGEREITRKDIDLLLPPRYEDDIFDLVELISIKRAKQAIDL
MDELIGRGQDPIFILSQIREQFQKLHRVKIRLSEKYRIDEIKKDFLEFSRVNLPDFVIEKFINQSKKFSNKQLNKCINLC
LYTEKKLKSNSNLNKKTELELMIVSTVI

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 41011; Mature: 41011

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLDGLYENLKKGKIEKSYILVGLDELLIKEGIENIIDNVLDEGFKDLNLIRLDGNNLN
CCCHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
FDDFMNACETLPFMSDKKVVVLNRTNIFRDKQDKETEKLYKQCIEYFQNTPEHCVLIAYT
HHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
TLKDKRDRVNRLSKLKKLEKSSCIVSVEKLKGAKLQQKVGRIFQRYNKNIGKIELKYFCD
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHH
SVENNFDVIEREVDKIVNYVGEREITRKDIDLLLPPRYEDDIFDLVELISIKRAKQAIDL
HHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MDELIGRGQDPIFILSQIREQFQKLHRVKIRLSEKYRIDEIKKDFLEFSRVNLPDFVIEK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
FINQSKKFSNKQLNKCINLCLYTEKKLKSNSNLNKKTELELMIVSTVI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCC
>Mature Secondary Structure
MIDLDGLYENLKKGKIEKSYILVGLDELLIKEGIENIIDNVLDEGFKDLNLIRLDGNNLN
CCCHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
FDDFMNACETLPFMSDKKVVVLNRTNIFRDKQDKETEKLYKQCIEYFQNTPEHCVLIAYT
HHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
TLKDKRDRVNRLSKLKKLEKSSCIVSVEKLKGAKLQQKVGRIFQRYNKNIGKIELKYFCD
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHH
SVENNFDVIEREVDKIVNYVGEREITRKDIDLLLPPRYEDDIFDLVELISIKRAKQAIDL
HHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MDELIGRGQDPIFILSQIREQFQKLHRVKIRLSEKYRIDEIKKDFLEFSRVNLPDFVIEK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHH
FINQSKKFSNKQLNKCINLCLYTEKKLKSNSNLNKKTELELMIVSTVI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]