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The map label for this gene is prmA [H]

Identifier: 18311009

GI number: 18311009

Start: 2318076

End: 2319017

Strand: Reverse

Name: prmA [H]

Synonym: CPE2027

Alternate gene names: 18311009

Gene position: 2319017-2318076 (Counterclockwise)

Preceding gene: 18311010

Following gene: 18311008

Centisome position: 76.5

GC content: 33.23

Gene sequence:

>942_bases
ATGGAAGGAACTTGGATTGAAGTTAGAGTAATAACTAAAAGTGAGGCATTAGAGCCTATATCAGGAATATTTTACGGATT
AGACTGTAAGGGTGTTGCCATAGAGGATCCAAATGATATATTAGGAAGAGAACAAGGACCTTTAACTTGGGATTTTGCAG
ATATAAACATATTAGAACATAAGGGGAAGGTTGCCGTTGTTAAAGGTTATTTCTCAGAAGAGGATAACATTGATGACGTA
ATAGCTTATGTTAAGGAAAGAGTAGAAGAGTTAAAAGAGTCAGGCTTAGATGTTGGTGAAGGAACAGTTGAAGCAGAAAA
AATGTTTGAAGAAGACTGGGCTAATAATTGGAAGAAATACTATAAGCCAATAAAGATTGGAGAAAAAATAGTTATAAAAC
CAATATGGGAAGAGTATGAGCCTACTGGAGAAGAAATGGTAGTAGAATTAGACCCAGGTATGGCTTTTGGTACTGGTGAC
CATGAAACTACAAGAATGTGTGTTCAAGCTTTAGATAAATATGTTAAGGCTGATACTACTGTATTTGATATTGGAACAGG
TTCAGGAATACTTGCTTTAGTTGCTTCTAAACTTGGTGCAAAACATGTTGTAGGAGTTGACTTAGACCCAGTTGCTGTAG
ATTCAGCTAAGGAAAATATATCATTTAACAATGTTGACAACATAGAAGTATTATATGGAAATCTTTTAGATGTTGTAGAT
GGAAAAGCTGATATAGTTGTTGCAAATATAATAGCTGAAATAATCTGCATACTAGTTGATGATGTTAAAAAAGCATTAAA
TAAAGATGGAATTTTCATAACTTCAGGTATAATACATGAGAGAAGACAAATGGTTATAGATAAATTAGAACAAGAAGGTT
TTGAGGTTATGGAAGTTAACAAAGATGGAGAATGGAACTGTATTGTTGCTAAGTTAAAATAA

Upstream 100 bases:

>100_bases
GCATATGAAACATAATAATGCTTATAAGCTAGACAGATACTACACTAAAGTGTAAAATAAATTATTAGCCAAAGTAGCAT
AAGAAAGGATTGATACATAA

Downstream 100 bases:

>100_bases
TTTAGTAAGGGAGTATAAAATTATGCATAAGTTTTTTACACCAGCGCATATGTTTTCAGACACTCATGCAAAAATAACAG
GGGAAGATGTAAAACATATT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MEGTWIEVRVITKSEALEPISGIFYGLDCKGVAIEDPNDILGREQGPLTWDFADINILEHKGKVAVVKGYFSEEDNIDDV
IAYVKERVEELKESGLDVGEGTVEAEKMFEEDWANNWKKYYKPIKIGEKIVIKPIWEEYEPTGEEMVVELDPGMAFGTGD
HETTRMCVQALDKYVKADTTVFDIGTGSGILALVASKLGAKHVVGVDLDPVAVDSAKENISFNNVDNIEVLYGNLLDVVD
GKADIVVANIIAEIICILVDDVKKALNKDGIFITSGIIHERRQMVIDKLEQEGFEVMEVNKDGEWNCIVAKLK

Sequences:

>Translated_313_residues
MEGTWIEVRVITKSEALEPISGIFYGLDCKGVAIEDPNDILGREQGPLTWDFADINILEHKGKVAVVKGYFSEEDNIDDV
IAYVKERVEELKESGLDVGEGTVEAEKMFEEDWANNWKKYYKPIKIGEKIVIKPIWEEYEPTGEEMVVELDPGMAFGTGD
HETTRMCVQALDKYVKADTTVFDIGTGSGILALVASKLGAKHVVGVDLDPVAVDSAKENISFNNVDNIEVLYGNLLDVVD
GKADIVVANIIAEIICILVDDVKKALNKDGIFITSGIIHERRQMVIDKLEQEGFEVMEVNKDGEWNCIVAKLK
>Mature_313_residues
MEGTWIEVRVITKSEALEPISGIFYGLDCKGVAIEDPNDILGREQGPLTWDFADINILEHKGKVAVVKGYFSEEDNIDDV
IAYVKERVEELKESGLDVGEGTVEAEKMFEEDWANNWKKYYKPIKIGEKIVIKPIWEEYEPTGEEMVVELDPGMAFGTGD
HETTRMCVQALDKYVKADTTVFDIGTGSGILALVASKLGAKHVVGVDLDPVAVDSAKENISFNNVDNIEVLYGNLLDVVD
GKADIVVANIIAEIICILVDDVKKALNKDGIFITSGIIHERRQMVIDKLEQEGFEVMEVNKDGEWNCIVAKLK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=187, Percent_Identity=38.5026737967914, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34756; Mature: 34756

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGTWIEVRVITKSEALEPISGIFYGLDCKGVAIEDPNDILGREQGPLTWDFADINILEH
CCCCEEEEEEEECCCCCCCHHHEEECCCCCCEEECCCHHHHCCCCCCEEEEEECEEEEEC
KGKVAVVKGYFSEEDNIDDVIAYVKERVEELKESGLDVGEGTVEAEKMFEEDWANNWKKY
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
YKPIKIGEKIVIKPIWEEYEPTGEEMVVELDPGMAFGTGDHETTRMCVQALDKYVKADTT
CCCHHCCCEEEEEECHHCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCE
VFDIGTGSGILALVASKLGAKHVVGVDLDPVAVDSAKENISFNNVDNIEVLYGNLLDVVD
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCEECCHHCCCCCCCCCCCEEECCCHHHHHC
GKADIVVANIIAEIICILVDDVKKALNKDGIFITSGIIHERRQMVIDKLEQEGFEVMEVN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEC
KDGEWNCIVAKLK
CCCCEEEEEEEEC
>Mature Secondary Structure
MEGTWIEVRVITKSEALEPISGIFYGLDCKGVAIEDPNDILGREQGPLTWDFADINILEH
CCCCEEEEEEEECCCCCCCHHHEEECCCCCCEEECCCHHHHCCCCCCEEEEEECEEEEEC
KGKVAVVKGYFSEEDNIDDVIAYVKERVEELKESGLDVGEGTVEAEKMFEEDWANNWKKY
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
YKPIKIGEKIVIKPIWEEYEPTGEEMVVELDPGMAFGTGDHETTRMCVQALDKYVKADTT
CCCHHCCCEEEEEECHHCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHCCCE
VFDIGTGSGILALVASKLGAKHVVGVDLDPVAVDSAKENISFNNVDNIEVLYGNLLDVVD
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCEECCHHCCCCCCCCCCCEEECCCHHHHHC
GKADIVVANIIAEIICILVDDVKKALNKDGIFITSGIIHERRQMVIDKLEQEGFEVMEVN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEEC
KDGEWNCIVAKLK
CCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA