| Definition | Clostridium perfringens str. 13, complete genome. |
|---|---|
| Accession | NC_003366 |
| Length | 3,031,430 |
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The map label for this gene is fabG [H]
Identifier: 18310909
GI number: 18310909
Start: 2208522
End: 2209268
Strand: Reverse
Name: fabG [H]
Synonym: CPE1927
Alternate gene names: 18310909
Gene position: 2209268-2208522 (Counterclockwise)
Preceding gene: 18310910
Following gene: 18310906
Centisome position: 72.88
GC content: 32.53
Gene sequence:
>747_bases ATGGAGAAAAAATTATTAGGAAAGATAGTATATATAACAGGAGCTTCAAAGGGAATTGGAAGAGGAATAGCAAGGGAATT TGGAAAGTCTGGAGCTTTTGTTTTAGTTGGATATAATAGTGATTTAGAAGGGGCTAATGAAACCTTGAATATGATTAAGG AACTAGGGGGTTCAGGAGAAATTTTAGGTGGAAATGTAGCAAATAAGGATGAGAGAAATAATATAGTAAGTTCCATTAAA AATAAGTTTGGAAAACTTGATGTATTAGTAAATAATGCTGGAATTTCAAAAATAGGATTATTTATGGATGCTAGTGATGA AGAGATAGATTCTATTATGAATGTTAACTTAATAGGTGCTATGAAGCTTACAAGGGATTCTATGGACTTATTAAGAGAAG GAAGTAATTCATCAATTATAAATATATCATCAATATGGGGAAATGTTGGAGCTTCCTGCGAAGTTTTATATTCAACTACT AAGGGAGGAATGAATTTATTTACTAAGGCCTTAGCAAAAGAAATAGCTCCTTGGGGAATAAGAGTAAATTGTATAGCTCC AGGTGTAATAAATACAGAGATGAATTCATGGCTTAGTAAAGAAGAAAAAGAGGGGCTAGAGGAAGAAATTCCTATGAATA GATTTGGAGAGGTTGAAGAGATTGGAAGAGTGGCAAAATTTTTAGCTTCAGAGGATTCTTCATACTTAACAGGACAAATA TTAACTGTAGATGGTGGAATGCTTTAA
Upstream 100 bases:
>100_bases TAAGATAGTCTTATAACTTAGTTATATAATGATTTATGAAAATAAACTTTAATACAACTTTTAAGAATTTTAATGTTATG CAGAAAAGGATGAAGGATTA
Downstream 100 bases:
>100_bases AAAAACTAAAAGATTCTATATAAAAATATAATAAAGCTTACAAACAATATGAAGAGAATATCTAGATGAGCTTTAGAATT TAAATTATTATGTAGAAGAT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MEKKLLGKIVYITGASKGIGRGIAREFGKSGAFVLVGYNSDLEGANETLNMIKELGGSGEILGGNVANKDERNNIVSSIK NKFGKLDVLVNNAGISKIGLFMDASDEEIDSIMNVNLIGAMKLTRDSMDLLREGSNSSIINISSIWGNVGASCEVLYSTT KGGMNLFTKALAKEIAPWGIRVNCIAPGVINTEMNSWLSKEEKEGLEEEIPMNRFGEVEEIGRVAKFLASEDSSYLTGQI LTVDGGML
Sequences:
>Translated_248_residues MEKKLLGKIVYITGASKGIGRGIAREFGKSGAFVLVGYNSDLEGANETLNMIKELGGSGEILGGNVANKDERNNIVSSIK NKFGKLDVLVNNAGISKIGLFMDASDEEIDSIMNVNLIGAMKLTRDSMDLLREGSNSSIINISSIWGNVGASCEVLYSTT KGGMNLFTKALAKEIAPWGIRVNCIAPGVINTEMNSWLSKEEKEGLEEEIPMNRFGEVEEIGRVAKFLASEDSSYLTGQI LTVDGGML >Mature_248_residues MEKKLLGKIVYITGASKGIGRGIAREFGKSGAFVLVGYNSDLEGANETLNMIKELGGSGEILGGNVANKDERNNIVSSIK NKFGKLDVLVNNAGISKIGLFMDASDEEIDSIMNVNLIGAMKLTRDSMDLLREGSNSSIINISSIWGNVGASCEVLYSTT KGGMNLFTKALAKEIAPWGIRVNCIAPGVINTEMNSWLSKEEKEGLEEEIPMNRFGEVEEIGRVAKFLASEDSSYLTGQI LTVDGGML
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=35.8333333333333, Blast_Score=149, Evalue=2e-36, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.9236947791165, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=31.5384615384615, Blast_Score=124, Evalue=9e-29, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.1587301587302, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=35.9307359307359, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=31.4741035856574, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.8039215686275, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=28.3505154639175, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI66933014, Length=180, Percent_Identity=31.1111111111111, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=27.6422764227642, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI142976729, Length=216, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4504505, Length=217, Percent_Identity=32.258064516129, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=27.2030651340996, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=30.9644670050761, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=24.896265560166, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=29.5336787564767, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.7435897435897, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI310128830, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI310115468, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI32455239, Length=194, Percent_Identity=31.4432989690722, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI5031765, Length=194, Percent_Identity=31.4432989690722, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI40254986, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI7705855, Length=213, Percent_Identity=28.169014084507, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI44680136, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI44680133, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI17738292, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI7657478, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=25.9459459459459, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=37.7593360995851, Blast_Score=162, Evalue=2e-41, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=36.71875, Blast_Score=149, Evalue=2e-37, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=32.6612903225806, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=32.1138211382114, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=31.9672131147541, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=32.1138211382114, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.5546558704453, Blast_Score=111, Evalue=3e-26, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=29.9595141700405, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=29.9180327868852, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=28.4, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789057, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=29.1891891891892, Blast_Score=64, Evalue=7e-12, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=35.2, Blast_Score=130, Evalue=5e-31, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=33.8709677419355, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.0395256916996, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=35.6, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=32.156862745098, Blast_Score=124, Evalue=6e-29, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.4110671936759, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=33.976833976834, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=33.976833976834, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=31.9852941176471, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=32.295719844358, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.9433962264151, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=30.7116104868914, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=30.5019305019305, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=32.183908045977, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.0813008130081, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.3207547169811, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=28.740157480315, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=32.4626865671642, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=30.4832713754647, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.0566037735849, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=28.7313432835821, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=29.5454545454545, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=26.1224489795918, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=27.8625954198473, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=29.0816326530612, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=31.0880829015544, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=29.5918367346939, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=28.7878787878788, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17558628, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=204, Percent_Identity=30.3921568627451, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=26.0204081632653, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17555612, Length=262, Percent_Identity=31.2977099236641, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI32563809, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17507613, Length=194, Percent_Identity=27.319587628866, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=2e-24, Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=34.5360824742268, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=26.3681592039801, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=35.4838709677419, Blast_Score=148, Evalue=3e-36, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=37.6518218623482, Blast_Score=141, Evalue=5e-34, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=3e-31, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=35.0393700787402, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=35.7429718875502, Blast_Score=124, Evalue=4e-29, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=34.6456692913386, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.4354838709677, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=27.8884462151394, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=32.7935222672065, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=28.2828282828283, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI281364892, Length=199, Percent_Identity=32.6633165829146, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI24640492, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221510726, Length=193, Percent_Identity=30.5699481865285, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=25.2525252525253, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26623; Mature: 26623
Theoretical pI: Translated: 4.62; Mature: 4.62
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 4.0 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 4.0 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEKKLLGKIVYITGASKGIGRGIAREFGKSGAFVLVGYNSDLEGANETLNMIKELGGSGE CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC ILGGNVANKDERNNIVSSIKNKFGKLDVLVNNAGISKIGLFMDASDEEIDSIMNVNLIGA EECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEEH MKLTRDSMDLLREGSNSSIINISSIWGNVGASCEVLYSTTKGGMNLFTKALAKEIAPWGI HHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCE RVNCIAPGVINTEMNSWLSKEEKEGLEEEIPMNRFGEVEEIGRVAKFLASEDSSYLTGQI EEEEECCCEECHHHHHHHCHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE LTVDGGML EEECCCCC >Mature Secondary Structure MEKKLLGKIVYITGASKGIGRGIAREFGKSGAFVLVGYNSDLEGANETLNMIKELGGSGE CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC ILGGNVANKDERNNIVSSIKNKFGKLDVLVNNAGISKIGLFMDASDEEIDSIMNVNLIGA EECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEEH MKLTRDSMDLLREGSNSSIINISSIWGNVGASCEVLYSTTKGGMNLFTKALAKEIAPWGI HHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCE RVNCIAPGVINTEMNSWLSKEEKEGLEEEIPMNRFGEVEEIGRVAKFLASEDSSYLTGQI EEEEECCCEECHHHHHHHCHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE LTVDGGML EEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]