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The map label for this gene is asd [H]

Identifier: 18310886

GI number: 18310886

Start: 2183294

End: 2184271

Strand: Direct

Name: asd [H]

Synonym: CPE1904

Alternate gene names: 18310886

Gene position: 2183294-2184271 (Clockwise)

Preceding gene: 18310882

Following gene: 18310887

Centisome position: 72.02

GC content: 31.49

Gene sequence:

>978_bases
GTGTACAATGTAGCAATAGTTGGGGCAACAGGAAATGTTGGAAGAAAATTCCTTGAAATCCTAGAAGAAAGAAATTTCCC
CGTTAAAGAATTATATTTATTCGCATCAAAAAGATCAGCAGGAAAAACTTTAAAATTTAAAGGTGAAGATGTATTAGTTG
AAGAATTATGCGAAGCTAATATTGAAAATAAGAAAATAGATTTTGCATTATTCTCAGCAGGCGGAAGTGTAAGCTTAGAA
TTTGCTCCTATTTTCGCAAAACATGGAGCAGTGGTTATAGATAACAGTAGTGCTTGGAGAATGAATAAAGAAGTTCCTTT
AGTAGTGCCAGAAGTAAATCCAGAGGATGTAAAATGGCATAAAGGTATTATTGCTAATCCAAACTGTTCTACAATTCAAG
CTATGGTAGCTTTAAAGCCACTATATGATAAATATGGTATAAAAAGAATAGTTTACTCAACTTACCAAGCAGTTTCAGGA
GCTGGAATTCAAGGTATATTAGATCTACAAGAAGGAACTACAAAGAAATTCCCATATCCTATATTAGGTAATGTAATTCC
TCATATAGATGTATTCTTAGATAATGGATACACAAAAGAAGAAATTAAAATGATTGAAGAAACAAAGAAAATACTTCATG
ATGATAATTTAAGAATAACTGCTACTACAGTTAGGGTACCAGTTTTAAATGCTCATAGTGAAAGTATAAATGTAGAGCTT
AATTCTGAATTTGAACTTGAAAATGTTATAGATTTATTTAATAGTTCTAAAGGAATAATAGTTCATGACGATGTAGAAAA
CTTAAAATACCCTACTCCACTTGAACTTAGTGGAAAAGACGAGGTCTTTGTTGGAAGAATAAGACGTGATTTCAGCTTAG
ACAATGGTCTTAACCTTTGGGTTGTGGCTGATAATATAAGAAAAGGGGCAGCTCTTAATGCAATTCAAATTGCTGAAATA
CTTATAAACGAAAAATAA

Upstream 100 bases:

>100_bases
TCAAATTAATCATAAAATATACTTGATAAAGTGTTTATCATTGAACTATATTTAATATATAGAAATAGAATATATTAAGA
TTATATTTAGGAGGGATATT

Downstream 100 bases:

>100_bases
TTTATTTTTTTGGAGGTAATACGTATGTTTAAAGGGTCTTGTGTAGCTTTAATAACACCATTTACTGAAGATGGCGTTAA
TTATGAAGAGCTAAGAAAAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MYNVAIVGATGNVGRKFLEILEERNFPVKELYLFASKRSAGKTLKFKGEDVLVEELCEANIENKKIDFALFSAGGSVSLE
FAPIFAKHGAVVIDNSSAWRMNKEVPLVVPEVNPEDVKWHKGIIANPNCSTIQAMVALKPLYDKYGIKRIVYSTYQAVSG
AGIQGILDLQEGTTKKFPYPILGNVIPHIDVFLDNGYTKEEIKMIEETKKILHDDNLRITATTVRVPVLNAHSESINVEL
NSEFELENVIDLFNSSKGIIVHDDVENLKYPTPLELSGKDEVFVGRIRRDFSLDNGLNLWVVADNIRKGAALNAIQIAEI
LINEK

Sequences:

>Translated_325_residues
MYNVAIVGATGNVGRKFLEILEERNFPVKELYLFASKRSAGKTLKFKGEDVLVEELCEANIENKKIDFALFSAGGSVSLE
FAPIFAKHGAVVIDNSSAWRMNKEVPLVVPEVNPEDVKWHKGIIANPNCSTIQAMVALKPLYDKYGIKRIVYSTYQAVSG
AGIQGILDLQEGTTKKFPYPILGNVIPHIDVFLDNGYTKEEIKMIEETKKILHDDNLRITATTVRVPVLNAHSESINVEL
NSEFELENVIDLFNSSKGIIVHDDVENLKYPTPLELSGKDEVFVGRIRRDFSLDNGLNLWVVADNIRKGAALNAIQIAEI
LINEK
>Mature_325_residues
MYNVAIVGATGNVGRKFLEILEERNFPVKELYLFASKRSAGKTLKFKGEDVLVEELCEANIENKKIDFALFSAGGSVSLE
FAPIFAKHGAVVIDNSSAWRMNKEVPLVVPEVNPEDVKWHKGIIANPNCSTIQAMVALKPLYDKYGIKRIVYSTYQAVSG
AGIQGILDLQEGTTKKFPYPILGNVIPHIDVFLDNGYTKEEIKMIEETKKILHDDNLRITATTVRVPVLNAHSESINVEL
NSEFELENVIDLFNSSKGIIVHDDVENLKYPTPLELSGKDEVFVGRIRRDFSLDNGLNLWVVADNIRKGAALNAIQIAEI
LINEK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=33.6283185840708, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=24.6498599439776, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=380, Percent_Identity=31.3157894736842, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36214; Mature: 36214

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNVAIVGATGNVGRKFLEILEERNFPVKELYLFASKRSAGKTLKFKGEDVLVEELCEAN
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEECCCHHHHHHHHHCC
IENKKIDFALFSAGGSVSLEFAPIFAKHGAVVIDNSSAWRMNKEVPLVVPEVNPEDVKWH
CCCCEEEEEEEECCCEEEEEEEEEEECCCEEEEECCCCEEECCCCCEEECCCCCCCCCEE
KGIIANPNCSTIQAMVALKPLYDKYGIKRIVYSTYQAVSGAGIQGILDLQEGTTKKFPYP
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
ILGNVIPHIDVFLDNGYTKEEIKMIEETKKILHDDNLRITATTVRVPVLNAHSESINVEL
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCEEEEEE
NSEFELENVIDLFNSSKGIIVHDDVENLKYPTPLELSGKDEVFVGRIRRDFSLDNGLNLW
CCCCCHHHHHHHHCCCCCEEEECCHHHCCCCCCEEECCCCCEEEEEEHHCCCCCCCCEEE
VVADNIRKGAALNAIQIAEILINEK
EEECCCCCCCCCCHHEEEEHHCCCC
>Mature Secondary Structure
MYNVAIVGATGNVGRKFLEILEERNFPVKELYLFASKRSAGKTLKFKGEDVLVEELCEAN
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEEECCCHHHHHHHHHCC
IENKKIDFALFSAGGSVSLEFAPIFAKHGAVVIDNSSAWRMNKEVPLVVPEVNPEDVKWH
CCCCEEEEEEEECCCEEEEEEEEEEECCCEEEEECCCCEEECCCCCEEECCCCCCCCCEE
KGIIANPNCSTIQAMVALKPLYDKYGIKRIVYSTYQAVSGAGIQGILDLQEGTTKKFPYP
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
ILGNVIPHIDVFLDNGYTKEEIKMIEETKKILHDDNLRITATTVRVPVLNAHSESINVEL
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCEEEEEE
NSEFELENVIDLFNSSKGIIVHDDVENLKYPTPLELSGKDEVFVGRIRRDFSLDNGLNLW
CCCCCHHHHHHHHCCCCCEEEECCHHHCCCCCCEEECCCCCEEEEEEHHCCCCCCCCEEE
VVADNIRKGAALNAIQIAEILINEK
EEECCCCCCCCCCHHEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]