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The map label for this gene is hisK [H]

Identifier: 18310865

GI number: 18310865

Start: 2162901

End: 2163689

Strand: Direct

Name: hisK [H]

Synonym: CPE1883

Alternate gene names: 18310865

Gene position: 2162901-2163689 (Clockwise)

Preceding gene: 18310849

Following gene: 18310878

Centisome position: 71.35

GC content: 27.0

Gene sequence:

>789_bases
ATGCTTTATGATTGTCACATACATACAGAATTTTCAGCTGACTCTGAATTAAAAATTAAGGATATATTAGAGAAGGCTAA
AAAAAATAATTTAGGAATAATAACTACAGAGCATTTAGATTATAATTTAAAAACTCATCCTCAATTTGCTGAACTTGATA
TTGAAGGTTATTTAAAGGAATATAGTAAATATAGAGGAGAAAATATGCAACAAGGTGTAGAACTTGGACTTGCAATGAAC
AATGTAGATGAAAACTTTGCCTTTTATGAAAAATACAAAGATAAATTTGATATGATAATAGGTTCTATTCATTCTATAAA
TGGTGTTACTCTTTCTAGATTTCTAAAACAAGATACTAGACCTAAAGAAGTTGTTTATGGTGAATATCTTAATAATATGC
TTAAATGCATAGAATTTTATGATATTTTTGATACCTTAGGACATATAGATTATCCTTGTAGATACAGTACTTATGATGAT
AAGGAAATGACTCTTACGGATTTTAAACCTAAATTCCAATCTATTTTTAAAACACTAATAGATAAAAATAAAGTTCTTGA
ACTTAATACTACTCGTTTAGATGATGAAACTTCCTTTAAAAACATGGTAGAAATATATTCATACTATAGAGAACTTGGAG
GTAAATATATAACCCTTGGTTCAGATTCTCACAAAATAGAGCATGTAGGTAGAAATTTCGAAAGACTTTATAAATTCTTA
GAAGAGACAAAATTAACTCCTTGTTACTTCAAGGACAGAAAATTAATTCCATGTTCATATCCCCTATAA

Upstream 100 bases:

>100_bases
TATAATAACTAAATAAATCTTAAAGTAATTTGCTTCCCTTATTATTTTTCTAAGTTATGATAAAATTAAATTATACTAAT
ATTTATGCGGAGGTTACAAA

Downstream 100 bases:

>100_bases
AAATAATTTTATTTTTTATTAAACCATAAAAAGACTGTAAGAAAATTTATTTTCACATAAATCTCTTACAGTCTCTAAAT
ACACTTTTATTTTTTCTTTA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLYDCHIHTEFSADSELKIKDILEKAKKNNLGIITTEHLDYNLKTHPQFAELDIEGYLKEYSKYRGENMQQGVELGLAMN
NVDENFAFYEKYKDKFDMIIGSIHSINGVTLSRFLKQDTRPKEVVYGEYLNNMLKCIEFYDIFDTLGHIDYPCRYSTYDD
KEMTLTDFKPKFQSIFKTLIDKNKVLELNTTRLDDETSFKNMVEIYSYYRELGGKYITLGSDSHKIEHVGRNFERLYKFL
EETKLTPCYFKDRKLIPCSYPL

Sequences:

>Translated_262_residues
MLYDCHIHTEFSADSELKIKDILEKAKKNNLGIITTEHLDYNLKTHPQFAELDIEGYLKEYSKYRGENMQQGVELGLAMN
NVDENFAFYEKYKDKFDMIIGSIHSINGVTLSRFLKQDTRPKEVVYGEYLNNMLKCIEFYDIFDTLGHIDYPCRYSTYDD
KEMTLTDFKPKFQSIFKTLIDKNKVLELNTTRLDDETSFKNMVEIYSYYRELGGKYITLGSDSHKIEHVGRNFERLYKFL
EETKLTPCYFKDRKLIPCSYPL
>Mature_262_residues
MLYDCHIHTEFSADSELKIKDILEKAKKNNLGIITTEHLDYNLKTHPQFAELDIEGYLKEYSKYRGENMQQGVELGLAMN
NVDENFAFYEKYKDKFDMIIGSIHSINGVTLSRFLKQDTRPKEVVYGEYLNNMLKCIEFYDIFDTLGHIDYPCRYSTYDD
KEMTLTDFKPKFQSIFKTLIDKNKVLELNTTRLDDETSFKNMVEIYSYYRELGGKYITLGSDSHKIEHVGRNFERLYKFL
EETKLTPCYFKDRKLIPCSYPL

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31023; Mature: 31023

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDCHIHTEFSADSELKIKDILEKAKKNNLGIITTEHLDYNLKTHPQFAELDIEGYLKE
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
YSKYRGENMQQGVELGLAMNNVDENFAFYEKYKDKFDMIIGSIHSINGVTLSRFLKQDTR
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
PKEVVYGEYLNNMLKCIEFYDIFDTLGHIDYPCRYSTYDDKEMTLTDFKPKFQSIFKTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
DKNKVLELNTTRLDDETSFKNMVEIYSYYRELGGKYITLGSDSHKIEHVGRNFERLYKFL
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCHHHHHHHH
EETKLTPCYFKDRKLIPCSYPL
HHCCCCCEEECCCEECCCCCCC
>Mature Secondary Structure
MLYDCHIHTEFSADSELKIKDILEKAKKNNLGIITTEHLDYNLKTHPQFAELDIEGYLKE
CEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
YSKYRGENMQQGVELGLAMNNVDENFAFYEKYKDKFDMIIGSIHSINGVTLSRFLKQDTR
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
PKEVVYGEYLNNMLKCIEFYDIFDTLGHIDYPCRYSTYDDKEMTLTDFKPKFQSIFKTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
DKNKVLELNTTRLDDETSFKNMVEIYSYYRELGGKYITLGSDSHKIEHVGRNFERLYKFL
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCHHHHHHHH
EETKLTPCYFKDRKLIPCSYPL
HHCCCCCEEECCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]