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The map label for this gene is mraY

Identifier: 18310842

GI number: 18310842

Start: 2128535

End: 2129488

Strand: Reverse

Name: mraY

Synonym: CPE1860

Alternate gene names: 18310842

Gene position: 2129488-2128535 (Counterclockwise)

Preceding gene: 18310843

Following gene: 18310841

Centisome position: 70.25

GC content: 30.4

Gene sequence:

>954_bases
ATGATAGATCCAAAGATAGTAATGGCAATAGTAATAAGTTTTATAGTAGCATCAATATTAGGACCTATTATAATTCCACT
ACTACATAAACTTAAATTTGGACAAAATATAAGACAAGAGGGACCAAAGAGTCACTTAAAAAAAGCAGGAACTCCAACTA
TAGGTGGATTAATATTTATTTTTGCAACTATTATAACAATGTTTATTATGGTTGGAAATCCAACAGATGAGGCTATGATA
GCTTTATATTCTTTCGTAGGATTTGGTTTTGTAGGATTTTTAGATGACTTACTAAAGATAATCAAGAAGAAAAATGAAGG
ATTAACATCAGGACAAAAAATGATTTTATTATTAATCGTATCAGGATTTTTAACTTGGTATGCTTATAAATATATAGGAA
CTAGCATTAATATACCATTTTTAAATGGGCAAATTAACTTCGGATTATTCTATATACCTTTTGTAATGTTCTACTTTGCA
GGGGTAACAAATGCGGTAAACTTAACAGATGGATTAGATGGATTAGCTACATCAGTTACTGTTTTAGTAACTACATTTTT
AGGGATAATTAGTTATAATTTAGGACACATAAGTTTAGCAATATTCTGTGTTGCTTTAGCAGGTGCATTACTTGCCTTCT
TAAGATTTAATGCATTTCCAGCTAGAGTATTTATGGGAGATACAGGTTCTCTTGCTTTAGGAGGAGCTGTAGCAATGGTG
GCATTAATACTAAAAATGCCTTTAATACTAGTGTTAATAGGAATTATCTACGTAATAGAAACACTTTCAGTTATATTACA
AGTTGCTTCATTCAAGCTTACAGGTAAGAGAATATTTAAAATGGCTCCTATACATCACCATTTTGAGCAACTAGGTTGGA
GTGAGACAAAGATAGTTTCTGTATTTTCTATAATAACAGTAGTATTTTGCTTCATTGCTTTTGCTTCACTTTAG

Upstream 100 bases:

>100_bases
GAAGAAATAACTAAAGCATTATTAGAAAAGTAAATGGAACTAAGGAGGTGAAGCTGCTTAATAGTTTAAGTAGCAGAATT
TTATGGAAATTTTAAAGTCA

Downstream 100 bases:

>100_bases
AAAATTCCTAAAATAGGAGGTTTTTAAATGAAGAAAAAAAAGACTACTAAAAAGAGTAATATTAACCCATTGGATTATGG
ACTTTTATATACAATAGTTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFIFATIITMFIMVGNPTDEAMI
ALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIVSGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFA
GVTNAVNLTDGLDGLATSVTVLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMV
ALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVSVFSIITVVFCFIAFASL

Sequences:

>Translated_317_residues
MIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFIFATIITMFIMVGNPTDEAMI
ALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIVSGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFA
GVTNAVNLTDGLDGLATSVTVLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMV
ALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVSVFSIITVVFCFIAFASL
>Mature_317_residues
MIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFIFATIITMFIMVGNPTDEAMI
ALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIVSGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFA
GVTNAVNLTDGLDGLATSVTVLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMV
ALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVSVFSIITVVFCFIAFASL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=333, Percent_Identity=39.6396396396396, Blast_Score=234, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CLOP1 (Q0TP97)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696543.1
- STRING:   Q0TP97
- GeneID:   4202574
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2114
- TIGR:   CPF_2114
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   CPER195103:CPF_2114-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 34502; Mature: 34502

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee32208)-; HASH(0xf2ebcf8)-; HASH(0xea11b8c)-; HASH(0xba6fc88)-; HASH(0xf410ebc)-; HASH(0xf372b18)-; HASH(0xf604960)-; HASH(0xb82d7d8)-; HASH(0xf834488)-; HASH(0xf35f734)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCHHHHHHH
FATIITMFIMVGNPTDEAMIALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFAGVTNAVNLTDGLDGLATSVT
HHHHHHHHHHHHCCEECCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
ALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VFSIITVVFCFIAFASL
HHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCHHHHHHH
FATIITMFIMVGNPTDEAMIALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFAGVTNAVNLTDGLDGLATSVT
HHHHHHHHHHHHCCEECCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMV
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
ALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VFSIITVVFCFIAFASL
HHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA