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The map label for this gene is spoVE [H]

Identifier: 18310841

GI number: 18310841

Start: 2127383

End: 2128507

Strand: Reverse

Name: spoVE [H]

Synonym: CPE1859

Alternate gene names: 18310841

Gene position: 2128507-2127383 (Counterclockwise)

Preceding gene: 18310842

Following gene: 18310840

Centisome position: 70.21

GC content: 32.0

Gene sequence:

>1125_bases
ATGAAGAAAAAAAAGACTACTAAAAAGAGTAATATTAACCCATTGGATTATGGACTTTTATATACAATAGTTATTTTATT
AGCTATTGGGGTGGTCATGGTTTATAGTGCCAGTTCATATTTTGCTATGGTTAACTATAATGATAGTACAGCTTTTTTGA
AAAAGCAGGCTTTATTTGCAGTAGTTGGTTTCATAGCTATGATATTTATATCAAGATGTGATTATCATAAACTTAAAAAA
TTAACAGGAATACTACTTATTATAACTCCTATATTATTGGTTGCTGTTTATGCATTCCCAGCAACCAAGGGAGCACAAAG
ATGGATAAAGTTAGGTCCACTTTCTTTCCAACCATCAGAACTTGCAAAATATGCGGTAGTTATAATCTTAGCTCATATGA
TTACCAATAAAGGTGAGAAGATTAAGGAGTTTTGGAAGGGAATAGTTCCTTGTTTCGTAATAGGGGGAGGATTTGCAGCT
CTTATACTTGCTCAGAAAAACCTTAGTATAGCAGCTGTAACTGGCTTTGTTACATTTATAATGGTTTTTGTTGCAGGTGC
AAGAAAAAGATTTATGTTTGGAGTAATAACTCCAATAATTTTATTTGCAGGTTCATTCTTTACTTTATTTGAGGATTATA
GAAGAAGAAGACTTTTAAACTTTATTAATCCTTGGAAAGATCCAGCTGGTGATGGATATCAGCTTATACAATCCTTTTAT
GCTTTAGGAGCAGGAGGAGTTACTGGACTTGGAATAGGACAATCAAGACAAAAAACTCTATACATGCCAGAGCCACATAA
TGACTTTATATTCGCAATAATAGGAGAAGAGTTAGGGTTAATAGGGTGTACAGTAGTAATATTATTATTTGTAATATTTG
TTTATAGAGGAATAAAAATAGCAATGAGTGCTAAAGATGAATATGGAACTTTATTAGCAGTAGGGATTACTTCTATTATA
GGATTACAAGCCATAATTAATATTGCCGTTGTAACAGGTTCAATGCCAGTTACAGGAGTTCCACTTCCATTTATAAGTTA
TGGAGGAACTGCACTTGTATTTAACTTAATGGCTATGGGAATTCTTCTTAATATATCAAGACAAAGAAATAAAAAGATTG
ATTAA

Upstream 100 bases:

>100_bases
TGAGACAAAGATAGTTTCTGTATTTTCTATAATAACAGTAGTATTTTGCTTCATTGCTTTTGCTTCACTTTAGAAAATTC
CTAAAATAGGAGGTTTTTAA

Downstream 100 bases:

>100_bases
AGGCGTTTTATACGCCTTTATTTTTTATTAAATTGTATTCATAATTTTAATAGTAATTTTTTACTATTAGTAATATTTTC
TTAAAAACTTAATGAAAAAA

Product: stage V sporulation protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKKKKTTKKSNINPLDYGLLYTIVILLAIGVVMVYSASSYFAMVNYNDSTAFLKKQALFAVVGFIAMIFISRCDYHKLKK
LTGILLIITPILLVAVYAFPATKGAQRWIKLGPLSFQPSELAKYAVVIILAHMITNKGEKIKEFWKGIVPCFVIGGGFAA
LILAQKNLSIAAVTGFVTFIMVFVAGARKRFMFGVITPIILFAGSFFTLFEDYRRRRLLNFINPWKDPAGDGYQLIQSFY
ALGAGGVTGLGIGQSRQKTLYMPEPHNDFIFAIIGEELGLIGCTVVILLFVIFVYRGIKIAMSAKDEYGTLLAVGITSII
GLQAIINIAVVTGSMPVTGVPLPFISYGGTALVFNLMAMGILLNISRQRNKKID

Sequences:

>Translated_374_residues
MKKKKTTKKSNINPLDYGLLYTIVILLAIGVVMVYSASSYFAMVNYNDSTAFLKKQALFAVVGFIAMIFISRCDYHKLKK
LTGILLIITPILLVAVYAFPATKGAQRWIKLGPLSFQPSELAKYAVVIILAHMITNKGEKIKEFWKGIVPCFVIGGGFAA
LILAQKNLSIAAVTGFVTFIMVFVAGARKRFMFGVITPIILFAGSFFTLFEDYRRRRLLNFINPWKDPAGDGYQLIQSFY
ALGAGGVTGLGIGQSRQKTLYMPEPHNDFIFAIIGEELGLIGCTVVILLFVIFVYRGIKIAMSAKDEYGTLLAVGITSII
GLQAIINIAVVTGSMPVTGVPLPFISYGGTALVFNLMAMGILLNISRQRNKKID
>Mature_374_residues
MKKKKTTKKSNINPLDYGLLYTIVILLAIGVVMVYSASSYFAMVNYNDSTAFLKKQALFAVVGFIAMIFISRCDYHKLKK
LTGILLIITPILLVAVYAFPATKGAQRWIKLGPLSFQPSELAKYAVVIILAHMITNKGEKIKEFWKGIVPCFVIGGGFAA
LILAQKNLSIAAVTGFVTFIMVFVAGARKRFMFGVITPIILFAGSFFTLFEDYRRRRLLNFINPWKDPAGDGYQLIQSFY
ALGAGGVTGLGIGQSRQKTLYMPEPHNDFIFAIIGEELGLIGCTVVILLFVIFVYRGIKIAMSAKDEYGTLLAVGITSII
GLQAIINIAVVTGSMPVTGVPLPFISYGGTALVFNLMAMGILLNISRQRNKKID

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=369, Percent_Identity=35.5013550135501, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1786853, Length=320, Percent_Identity=35.9375, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41032; Mature: 41032

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKTTKKSNINPLDYGLLYTIVILLAIGVVMVYSASSYFAMVNYNDSTAFLKKQALFA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
VVGFIAMIFISRCDYHKLKKLTGILLIITPILLVAVYAFPATKGAQRWIKLGPLSFQPSE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCHHH
LAKYAVVIILAHMITNKGEKIKEFWKGIVPCFVIGGGFAALILAQKNLSIAAVTGFVTFI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHH
MVFVAGARKRFMFGVITPIILFAGSFFTLFEDYRRRRLLNFINPWKDPAGDGYQLIQSFY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALGAGGVTGLGIGQSRQKTLYMPEPHNDFIFAIIGEELGLIGCTVVILLFVIFVYRGIKI
HHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEE
AMSAKDEYGTLLAVGITSIIGLQAIINIAVVTGSMPVTGVPLPFISYGGTALVFNLMAMG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCHHHHHHHHHHH
ILLNISRQRNKKID
HHHHHHHHHCCCCC
>Mature Secondary Structure
MKKKKTTKKSNINPLDYGLLYTIVILLAIGVVMVYSASSYFAMVNYNDSTAFLKKQALFA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
VVGFIAMIFISRCDYHKLKKLTGILLIITPILLVAVYAFPATKGAQRWIKLGPLSFQPSE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCHHH
LAKYAVVIILAHMITNKGEKIKEFWKGIVPCFVIGGGFAALILAQKNLSIAAVTGFVTFI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHH
MVFVAGARKRFMFGVITPIILFAGSFFTLFEDYRRRRLLNFINPWKDPAGDGYQLIQSFY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALGAGGVTGLGIGQSRQKTLYMPEPHNDFIFAIIGEELGLIGCTVVILLFVIFVYRGIKI
HHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEE
AMSAKDEYGTLLAVGITSIIGLQAIINIAVVTGSMPVTGVPLPFISYGGTALVFNLMAMG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCHHHHHHHHHHH
ILLNISRQRNKKID
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]