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The map label for this gene is ppnK [H]

Identifier: 18310799

GI number: 18310799

Start: 2095482

End: 2096312

Strand: Reverse

Name: ppnK [H]

Synonym: CPE1817

Alternate gene names: 18310799

Gene position: 2096312-2095482 (Counterclockwise)

Preceding gene: 18310800

Following gene: 18310798

Centisome position: 69.15

GC content: 28.4

Gene sequence:

>831_bases
ATGAGAAATATAGGAATTATAATTAATAAAGAAAAAGATAAAGAAAATAAAATTTTAAATTTGGTTATTTTAAAGGTTAA
AGAATATCTAAATCCTGATGAAATAAAAGTTATAGACCAATTTTATAAGGGAGATTATAAAGATTTAATGTCTTTAGATC
TTTTAATAGTCCTTGGTGGAGATGGAACGCTTTTAGGTGTGGCTAGAAAATTCTCTACAGTTATAGATACTCCAATTTTA
GGAATTAACATTGGAAATTTAGGCTTTTTAGTTACAGCTGAGATAAGCGAATTAGATGAAGCTTTATATAGAATAAAGGT
TGGTGATTATAAGGTAGAGGAAAGAATGTTACTTTCTTGTACTATAGAAGGGGTAACTTGTTCAGAGGAAAGGGCTTTAA
ATGATATTGTTGTTGCTAGGGGAACATTATCTAGAATGGCACAATATGAGGTCTTTATAAATGATGAACTTTATGCTACT
TTTAAAGGGGATGGAGTTATAATTTCTACTCCAGTTGGATCAACAGCCTATTCTTTTTCAGCTGGAGGCCCGCTTATAAT
GCCAGATTTACAAATAGTATCAATAGTCCCTATATGTCCTCATACACCTAATTCAAGACCTATGATAATAGATGGAAATA
ACAAGGTAAGAGTTAAGCCTCTTATTAATGAATCAGATGTCTTTGTTACAATAGATGGACAAAAAGCATTAAAGTTAGAA
AAACATAATGAAGTTTTAATAAAAAAAGCAAAAGAATTTTTTAGAATAATTTCATTTGATAATAAAAGTTATTTTAAGGT
ACTAAGGAAAAAATTATTTAAGATAGAATAA

Upstream 100 bases:

>100_bases
TCATAGTGATTTATAAAGATTAAATTATTAAATAAGAAATATTAATTTTATAATTACTTTAGAGAGACTGCATAGTTAAA
GTAAAGGTGTGTTTTGGGGC

Downstream 100 bases:

>100_bases
ATATTATGAAGGTGAGTTGAAGATGAAATCTAAGAGACATTCTAAGATAATTGAAATTATAAAATCAACAGCGATAGAAA
CTCAAGAAGAGTTAGCGGAA

Product: NAD(+)/NADH kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRNIGIIINKEKDKENKILNLVILKVKEYLNPDEIKVIDQFYKGDYKDLMSLDLLIVLGGDGTLLGVARKFSTVIDTPIL
GINIGNLGFLVTAEISELDEALYRIKVGDYKVEERMLLSCTIEGVTCSEERALNDIVVARGTLSRMAQYEVFINDELYAT
FKGDGVIISTPVGSTAYSFSAGGPLIMPDLQIVSIVPICPHTPNSRPMIIDGNNKVRVKPLINESDVFVTIDGQKALKLE
KHNEVLIKKAKEFFRIISFDNKSYFKVLRKKLFKIE

Sequences:

>Translated_276_residues
MRNIGIIINKEKDKENKILNLVILKVKEYLNPDEIKVIDQFYKGDYKDLMSLDLLIVLGGDGTLLGVARKFSTVIDTPIL
GINIGNLGFLVTAEISELDEALYRIKVGDYKVEERMLLSCTIEGVTCSEERALNDIVVARGTLSRMAQYEVFINDELYAT
FKGDGVIISTPVGSTAYSFSAGGPLIMPDLQIVSIVPICPHTPNSRPMIIDGNNKVRVKPLINESDVFVTIDGQKALKLE
KHNEVLIKKAKEFFRIISFDNKSYFKVLRKKLFKIE
>Mature_276_residues
MRNIGIIINKEKDKENKILNLVILKVKEYLNPDEIKVIDQFYKGDYKDLMSLDLLIVLGGDGTLLGVARKFSTVIDTPIL
GINIGNLGFLVTAEISELDEALYRIKVGDYKVEERMLLSCTIEGVTCSEERALNDIVVARGTLSRMAQYEVFINDELYAT
FKGDGVIISTPVGSTAYSFSAGGPLIMPDLQIVSIVPICPHTPNSRPMIIDGNNKVRVKPLINESDVFVTIDGQKALKLE
KHNEVLIKKAKEFFRIISFDNKSYFKVLRKKLFKIE

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=237, Percent_Identity=27.8481012658228, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1788968, Length=223, Percent_Identity=37.6681614349776, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320794, Length=263, Percent_Identity=31.5589353612167, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322509, Length=263, Percent_Identity=28.1368821292776, Blast_Score=115, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=183, Percent_Identity=32.7868852459016, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573832, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573826, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573830, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161077047, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573828, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24653424, Length=212, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363323, Length=212, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363321, Length=212, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24653422, Length=212, Percent_Identity=25, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20129957, Length=213, Percent_Identity=24.8826291079812, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30963; Mature: 30963

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIGIIINKEKDKENKILNLVILKVKEYLNPDEIKVIDQFYKGDYKDLMSLDLLIVLGG
CCCEEEEEECCCCCCCCEEHHEEEEHHHHCCCCHHHHHHHHHCCCHHHHCCEEEEEEECC
DGTLLGVARKFSTVIDTPILGINIGNLGFLVTAEISELDEALYRIKVGDYKVEERMLLSC
CCEEEHHHHHHHHHHCCCEEEEEECCEEEEEEEEHHHHHHHHHEEEECCEEECCEEEEEE
TIEGVTCSEERALNDIVVARGTLSRMAQYEVFINDELYATFKGDGVIISTPVGSTAYSFS
EEECEECCHHHCCHHEEEECCHHHHHEEEEEEECCEEEEEEECCCEEEECCCCCCEEEEC
AGGPLIMPDLQIVSIVPICPHTPNSRPMIIDGNNKVRVKPLINESDVFVTIDGQKALKLE
CCCCEEECCCEEEEEEEECCCCCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCEEEEE
KHNEVLIKKAKEFFRIISFDNKSYFKVLRKKLFKIE
CCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRNIGIIINKEKDKENKILNLVILKVKEYLNPDEIKVIDQFYKGDYKDLMSLDLLIVLGG
CCCEEEEEECCCCCCCCEEHHEEEEHHHHCCCCHHHHHHHHHCCCHHHHCCEEEEEEECC
DGTLLGVARKFSTVIDTPILGINIGNLGFLVTAEISELDEALYRIKVGDYKVEERMLLSC
CCEEEHHHHHHHHHHCCCEEEEEECCEEEEEEEEHHHHHHHHHEEEECCEEECCEEEEEE
TIEGVTCSEERALNDIVVARGTLSRMAQYEVFINDELYATFKGDGVIISTPVGSTAYSFS
EEECEECCHHHCCHHEEEECCHHHHHEEEEEEECCEEEEEEECCCEEEECCCCCCEEEEC
AGGPLIMPDLQIVSIVPICPHTPNSRPMIIDGNNKVRVKPLINESDVFVTIDGQKALKLE
CCCCEEECCCEEEEEEEECCCCCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCEEEEE
KHNEVLIKKAKEFFRIISFDNKSYFKVLRKKLFKIE
CCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA