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The map label for this gene is nudF [H]

Identifier: 18310792

GI number: 18310792

Start: 2089979

End: 2090509

Strand: Reverse

Name: nudF [H]

Synonym: CPE1810

Alternate gene names: 18310792

Gene position: 2090509-2089979 (Counterclockwise)

Preceding gene: 18310793

Following gene: 18310791

Centisome position: 68.96

GC content: 28.81

Gene sequence:

>531_bases
ATGGATTTATATGAGAAAACTTTAAGTGAGGAGAGCATATTTAAGTGTTCTTTTATGGAACTTGTTAAGCAAAAGGTGAA
ATTACCAGATGGCAATGAGGCAGAAAGAGATATTGTTAAACATTCAAATGGGGTTTGTGTTATAGCTTTCAATGAAAAAG
GAAATATTCTTATGGTAGAACAGTTTAGAAAGCCTTTTAATAGAGTGTTTTTAGAATTACCAGCAGGAAAGGTTGATAAG
GAAGAAATATTAGAAAAAGCAGCCTTACGAGAACTTAAAGAAGAGACAGGGTATTTAGCTAATAAGATAACATATTTAGG
ACAAATAGCACCATCACCAGGATTTTGTGATGAAGTAGTTTACTTATATAAAGCTCATGAACTTAAAAAGGGAGAAACTA
ATTTTGATCATGATGAATTTTTAAATTTAAAAGAATATCCATTAGAAGAAGTTAAAAATATGATTATAGAGGGTAGAATA
ACTGATGCAAAAACTATAGCATGTTTATTTTTCTATGAAAATATTAAATAA

Upstream 100 bases:

>100_bases
AGTGAGGATTTTTCACAAATATCCTTTAAAATTTTATAATATTTATATAAATTAAAAAAATAATTTTAGATTTTTTAGGT
TCAAAATTGAGGTGAGATAT

Downstream 100 bases:

>100_bases
TGAGAAATAGGAACTAGAGTATTTGAGTTTACTTTAGTTCTATTTTTTTTAATAAATTTAAATAATTTAATTATAAACTT
ATCTAGTCCTAAATATTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MDLYEKTLSEESIFKCSFMELVKQKVKLPDGNEAERDIVKHSNGVCVIAFNEKGNILMVEQFRKPFNRVFLELPAGKVDK
EEILEKAALRELKEETGYLANKITYLGQIAPSPGFCDEVVYLYKAHELKKGETNFDHDEFLNLKEYPLEEVKNMIIEGRI
TDAKTIACLFFYENIK

Sequences:

>Translated_176_residues
MDLYEKTLSEESIFKCSFMELVKQKVKLPDGNEAERDIVKHSNGVCVIAFNEKGNILMVEQFRKPFNRVFLELPAGKVDK
EEILEKAALRELKEETGYLANKITYLGQIAPSPGFCDEVVYLYKAHELKKGETNFDHDEFLNLKEYPLEEVKNMIIEGRI
TDAKTIACLFFYENIK
>Mature_176_residues
MDLYEKTLSEESIFKCSFMELVKQKVKLPDGNEAERDIVKHSNGVCVIAFNEKGNILMVEQFRKPFNRVFLELPAGKVDK
EEILEKAALRELKEETGYLANKITYLGQIAPSPGFCDEVVYLYKAHELKKGETNFDHDEFLNLKEYPLEEVKNMIIEGRI
TDAKTIACLFFYENIK

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319587, Length=160, Percent_Identity=33.125, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 20352; Mature: 20352

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYEKTLSEESIFKCSFMELVKQKVKLPDGNEAERDIVKHSNGVCVIAFNEKGNILMVE
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEHH
QFRKPFNRVFLELPAGKVDKEEILEKAALRELKEETGYLANKITYLGQIAPSPGFCDEVV
HHHCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
YLYKAHELKKGETNFDHDEFLNLKEYPLEEVKNMIIEGRITDAKTIACLFFYENIK
HHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCC
>Mature Secondary Structure
MDLYEKTLSEESIFKCSFMELVKQKVKLPDGNEAERDIVKHSNGVCVIAFNEKGNILMVE
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEHH
QFRKPFNRVFLELPAGKVDKEEILEKAALRELKEETGYLANKITYLGQIAPSPGFCDEVV
HHHCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
YLYKAHELKKGETNFDHDEFLNLKEYPLEEVKNMIIEGRITDAKTIACLFFYENIK
HHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]