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The map label for this gene is engA

Identifier: 18310737

GI number: 18310737

Start: 2033094

End: 2034410

Strand: Reverse

Name: engA

Synonym: CPE1755

Alternate gene names: 18310737

Gene position: 2034410-2033094 (Counterclockwise)

Preceding gene: 18310738

Following gene: 18310736

Centisome position: 67.11

GC content: 30.98

Gene sequence:

>1317_bases
ATGAGTAAACCAATAGTTGCTATGGTTGGAAGACCGAACGTAGGTAAGTCGACTCTTTTCAATAAATTAGCAGGAAAAAG
AATTTCAATAGTACAAGATACACCAGGGGTTACTAGAGACAGAGTATATGCAGAATCAGAATGGTTAAACAGAAAATTCA
CAATGATAGATACAGGTGGAATAGAGCCTGAGAGTAGTGATATAATTGTTAAACAAATGAGAAGACAAGCGCAAATTGCT
ATAGAAATGGCTGATGTAATAGTATTCGTTGTTGATGGTAAGGAAGGACTTACTGCTGCTGACCAAGAAGTTGCACAAAT
GCTTAGAAAAAGTAAAAAGCCTGTTGTTTTAGTAGTTAATAAAATAGATAGATTAGCTTTAGAAGAAAATAGCTATGAAT
TCTACAATTTAGGCATTGGAGATCCTATAACTATATCAGCATCTCAAGGATTAGGACTTGGAGATATGCTAGATGAAGTT
GTTAAATATTTCAATGATCCTTCAGAAGATGAAGAGGATGATGAATATATTAGAATAGCTATGATAGGTAAACCAAATGT
AGGTAAATCATCACTTATAAATAGATTATTAGGTGAAGAGAGAGTTATAGTAAGTAATGTTCCAGGAACAACAAGGGATT
CTATAGATAGTTACTTAGAAACAGAAGATGGAAAATTCATCTTAGTTGATACTGCTGGATTAAGAAGAAAAAGTAAAGTA
AAAGAAGAAATAGAAAGATATAGTGTAATCAGAACTTATGCTGCTATAGAGAAAGCTGATGTAGCTATACTTGTAATAGA
TGCTGAGCAAGGAATAACTGAGCAAGATGAAAAAATAATAGGATATGCTCATGAAATGAATAAAGCAATTATGGTTGTTG
TAAATAAATGGGATCTTATTGAAAAAGATGATAAAACATTAAGTAATTATCAAAAAGACTTACAACAAAAACTTAAGTTT
ATGCCATATGCTAAATACTTATTCATATCAGCTTTAACAGGACAAAGAGTACATAAAATATTATCAACAGCTAAATATTG
TTATGATAATTACTCTAAGAGAGTTTCAACTGGATTATTAAATGATGTTATAAGTAAGGCTGTTTTAATGAAAGAGCCAC
CAGTTGTAGCCTTAAAGAGATTAAAAATATACTATGCTACTCAGGTTGCTACAAAGCCACCTAAGTTTGTGTTCTTTGTA
AATGACCCTAATTTATTACATTTCTCATATGGTAGATATTTAGAAAACCAATTAAGAGAAAGTTTTGATTTTGATGGAAC
TGGTATAGAAATAGAATATAGAGCTAGAAAGGAGTAA

Upstream 100 bases:

>100_bases
AGGATATTGAGGAAAGATTGGGAGTTAAAGTTATAGTTTGTAGCTATACAGGGGAAGACCTAATAGACTTAATAAATGAA
CACTGTGAGGAGGAATAAGA

Downstream 100 bases:

>100_bases
TTTTATGAGTAAAGTGGCTTTTTTAGGAGCAGGAAGTTTTGGAACTTCTTTAGGTATATTATTGGGGAATAAAGGTGTTA
CGGTTTCTCTGTGGGATAGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGGIEPESSDIIVKQMRRQAQIA
IEMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVNKIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEV
VKYFNDPSEDEEDDEYIRIAMIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKV
KEEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLIEKDDKTLSNYQKDLQQKLKF
MPYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLLNDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFV
NDPNLLHFSYGRYLENQLRESFDFDGTGIEIEYRARKE

Sequences:

>Translated_438_residues
MSKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGGIEPESSDIIVKQMRRQAQIA
IEMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVNKIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEV
VKYFNDPSEDEEDDEYIRIAMIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKV
KEEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLIEKDDKTLSNYQKDLQQKLKF
MPYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLLNDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFV
NDPNLLHFSYGRYLENQLRESFDFDGTGIEIEYRARKE
>Mature_437_residues
SKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGGIEPESSDIIVKQMRRQAQIAI
EMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVNKIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEVV
KYFNDPSEDEEDDEYIRIAMIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKVK
EEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLIEKDDKTLSNYQKDLQQKLKFM
PYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLLNDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFVN
DPNLLHFSYGRYLENQLRESFDFDGTGIEIEYRARKE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=40.7407407407407, Blast_Score=343, Evalue=9e-96,
Organism=Escherichia coli, GI1788919, Length=243, Percent_Identity=30.0411522633745, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=38.2978723404255, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17507259, Length=191, Percent_Identity=32.4607329842932, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=205, Percent_Identity=33.6585365853659, Blast_Score=97, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CLOP1 (Q0TPJ9)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696441.1
- ProteinModelPortal:   Q0TPJ9
- SMR:   Q0TPJ9
- STRING:   Q0TPJ9
- GeneID:   4202478
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2008
- TIGR:   CPF_2008
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   CPER195103:CPF_2008-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49587; Mature: 49455

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHEEEHHHHCCCEEEEEECCC
IEPESSDIIVKQMRRQAQIAIEMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEE
KIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEVVKYFNDPSEDEEDDEYIRIA
CCCHHEECCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
MIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKV
EECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHH
KEEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLI
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCC
EKDDKTLSNYQKDLQQKLKFMPYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFVNDPNLLHFSYGRYLENQLRE
HHHHHHHHHHCCCCHHHHHHEEEEEEEEECCCCCCEEEEECCCCEEEEHHHHHHHHHHHH
SFDFDGTGIEIEYRARKE
HCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGG
CCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHEEEHHHHCCCEEEEEECCC
IEPESSDIIVKQMRRQAQIAIEMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEE
KIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEVVKYFNDPSEDEEDDEYIRIA
CCCHHEECCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
MIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKV
EECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHH
KEEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLI
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCC
EKDDKTLSNYQKDLQQKLKFMPYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLL
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFVNDPNLLHFSYGRYLENQLRE
HHHHHHHHHHCCCCHHHHHHEEEEEEEEECCCCCCEEEEECCCCEEEEHHHHHHHHHHHH
SFDFDGTGIEIEYRARKE
HCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA