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The map label for this gene is rpe [H]

Identifier: 18310718

GI number: 18310718

Start: 2012577

End: 2013230

Strand: Reverse

Name: rpe [H]

Synonym: CPE1736

Alternate gene names: 18310718

Gene position: 2013230-2012577 (Counterclockwise)

Preceding gene: 18310719

Following gene: 18310717

Centisome position: 66.41

GC content: 31.5

Gene sequence:

>654_bases
ATGGTTAAAATAGCACCATCAATATTATCAGCAGATTTTAGTATTTTAGGAGAACAAGTTAAGAGAGTAGAAAAAGGTGG
GGCAGAGTTCTTACATATAGATGTAATGGATGGTCATTTTGTTCCAAATATAAGCTTTGGATTTCCAATAATGAAAGCTA
TAAGGAACTTAAGCAATCTTGTTTTTGATGTTCACTTAATGATAGAAGAGCCAGGAAGATATGTAGATGAATTTATAAGT
GCAGGAGCAGATTTAATAACTGTACATTATGAAGCTGATAGACATATTGATAGAACAATAAATTATATAAAAAGTAAAGG
ATGCAAGGCTGGAATAGCTTTAAATCCAGGTACACCAGTTTCAATGCTTAAGAATTTAATACCTTCATTAGATATGGTAT
TAATAATGTCTGTTAATCCAGGGTTTGGAGGACAAAGCTTTATACCATATAGTTTAGATAAGATAAAAGAAGTAAAAGAA
ATGGCTAAGGCTTGTGGTAAGGAAGACTTATTAATCCAAGTTGATGGAGGAGTAGGTGCAAATAATATAAAAGAGATAGT
AGAAGCTGGAGCTAATGTTTTAGTTGCTGGATCAGCTGTATTTAAAGAAGATAAAATAGAAGAAAACATTAAAGCTTTAA
GAGAGGCACTATAA

Upstream 100 bases:

>100_bases
GTGCTGTAAAAGAAGCAGTTGAAGAGGGTAAAATAAACAAGCTAAGATATGAATTTTATATAAAAACCTTAGAAGAGATA
ATAAATAGGAGGGGTAATTA

Downstream 100 bases:

>100_bases
AATGAAAGTTCTTATAATAGCTGGGGGAGAAAAGCCTAGTAGTGAGTTATTAAAAAGTGAAATTAAAGAGTGTGACTTAT
TAATAGCTGCTGATAGGGGA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MVKIAPSILSADFSILGEQVKRVEKGGAEFLHIDVMDGHFVPNISFGFPIMKAIRNLSNLVFDVHLMIEEPGRYVDEFIS
AGADLITVHYEADRHIDRTINYIKSKGCKAGIALNPGTPVSMLKNLIPSLDMVLIMSVNPGFGGQSFIPYSLDKIKEVKE
MAKACGKEDLLIQVDGGVGANNIKEIVEAGANVLVAGSAVFKEDKIEENIKALREAL

Sequences:

>Translated_217_residues
MVKIAPSILSADFSILGEQVKRVEKGGAEFLHIDVMDGHFVPNISFGFPIMKAIRNLSNLVFDVHLMIEEPGRYVDEFIS
AGADLITVHYEADRHIDRTINYIKSKGCKAGIALNPGTPVSMLKNLIPSLDMVLIMSVNPGFGGQSFIPYSLDKIKEVKE
MAKACGKEDLLIQVDGGVGANNIKEIVEAGANVLVAGSAVFKEDKIEENIKALREAL
>Mature_217_residues
MVKIAPSILSADFSILGEQVKRVEKGGAEFLHIDVMDGHFVPNISFGFPIMKAIRNLSNLVFDVHLMIEEPGRYVDEFIS
AGADLITVHYEADRHIDRTINYIKSKGCKAGIALNPGTPVSMLKNLIPSLDMVLIMSVNPGFGGQSFIPYSLDKIKEVKE
MAKACGKEDLLIQVDGGVGANNIKEIVEAGANVLVAGSAVFKEDKIEENIKALREAL

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=215, Percent_Identity=40, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI219879828, Length=215, Percent_Identity=38.1395348837209, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=32.5443786982249, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI1789788, Length=215, Percent_Identity=49.7674418604651, Blast_Score=214, Evalue=3e-57,
Organism=Escherichia coli, GI1790523, Length=199, Percent_Identity=37.1859296482412, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=27.536231884058, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=39.2694063926941, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322341, Length=230, Percent_Identity=45.6521739130435, Blast_Score=186, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24586301, Length=216, Percent_Identity=40.2777777777778, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23598; Mature: 23598

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIAPSILSADFSILGEQVKRVEKGGAEFLHIDVMDGHFVPNISFGFPIMKAIRNLSNL
CCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VFDVHLMIEEPGRYVDEFISAGADLITVHYEADRHIDRTINYIKSKGCKAGIALNPGTPV
HHEEEEEEECCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCH
SMLKNLIPSLDMVLIMSVNPGFGGQSFIPYSLDKIKEVKEMAKACGKEDLLIQVDGGVGA
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCH
NNIKEIVEAGANVLVAGSAVFKEDKIEENIKALREAL
HHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKIAPSILSADFSILGEQVKRVEKGGAEFLHIDVMDGHFVPNISFGFPIMKAIRNLSNL
CCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VFDVHLMIEEPGRYVDEFISAGADLITVHYEADRHIDRTINYIKSKGCKAGIALNPGTPV
HHEEEEEEECCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCH
SMLKNLIPSLDMVLIMSVNPGFGGQSFIPYSLDKIKEVKEMAKACGKEDLLIQVDGGVGA
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCH
NNIKEIVEAGANVLVAGSAVFKEDKIEENIKALREAL
HHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]