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The map label for this gene is tsf

Identifier: 18310681

GI number: 18310681

Start: 1977447

End: 1978358

Strand: Reverse

Name: tsf

Synonym: CPE1699

Alternate gene names: 18310681

Gene position: 1978358-1977447 (Counterclockwise)

Preceding gene: 18310682

Following gene: 18310680

Centisome position: 65.26

GC content: 35.64

Gene sequence:

>912_bases
ATGATAACAGCTAAAGCAGTTAAAGAGTTAAGAGAAAGAACTGGCGCAGGAATGATGGATTGTAAAAAAGCGCTAACTGA
AACTAATGGAGATATGGAAAAAGCAGTTGAAGTTTTAAGAGAAAAAGGATTAGCAGCTGCAGCTAAAAAAGCTGGAAGAG
TAGCAGCTGAAGGTATCGTTAAAACTTACGTATCAGAAGATATGAAAAAAGGTTCAATAGTTGAAATCAACTGTGAAACT
GACTTCGTTGCTTTAAACGAAGAATTCGTTGGATTTGCAGGAAGAGTAGCAGAATTAGTTGCTAACTCAAATGTAAACAC
TGTAGAAGAATTATTAGCAGAAAAATTAGACGGAGACAAAACTGTTCAAGAAGTTTTAACTGAGTTAATCGCTAAGATCG
GTGAAAACATGAGCGTAAGAAGATTCGAAAGATTCTCTGTTGAAAGCGGATTAGTTCAAAGCTACATCCACGGTGGAGGA
AGAATAGGTGTTATGGCTGAATTAGCATGTGAAGCTTCATCACCAGTATTAGCTGAAGTTGCTAAAGATGTTTGTATGCA
AATAGCTGCTGCTAACCCACTATTCTTATCAGAAGCTGATGTTGATCAAGAATCTTTAGAAAAAGAAAAAGAAATATACA
GAGCTCAAGCTCTTAACGAAGGTAAACCAGAGCACATCGTTGATAAGATGGTAATGGGAAGAATCAAAAAATACTGTAAA
GAAGTTTGTCTTTTAGATCAAGCTTGGGTAAAAGATGGCGACAAATCAATCGCTAAATTATTAGAAGAAAAATCAAAAGA
AGTAGGTTCTCCAATAACTATAACTAAGTTCGTAAGATTCGAAAGAGGAGAAGGAATCGAAAAGAAAGAAGAAAACTTCG
CTGAAGAAGTAGCTAAAATGGGCGGAAAATAA

Upstream 100 bases:

>100_bases
GGCGAGCAATTAGCAGAGTAATATTAAGATAAATACTGAAAAGGTAGATGAAGCTCTCTGCTTCGTTTACCTTTTAATTA
AATAGTCAGGAGGAATTTCA

Downstream 100 bases:

>100_bases
TAACATAAGAGAACACATTGTGTTCTCTTTTTTTAGAATATAGATATAAAAAATTAACAAAAATAGAGAATTCAGCGTTT
TGGAGGTTTAAGATGGGAAC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MITAKAVKELRERTGAGMMDCKKALTETNGDMEKAVEVLREKGLAAAAKKAGRVAAEGIVKTYVSEDMKKGSIVEINCET
DFVALNEEFVGFAGRVAELVANSNVNTVEELLAEKLDGDKTVQEVLTELIAKIGENMSVRRFERFSVESGLVQSYIHGGG
RIGVMAELACEASSPVLAEVAKDVCMQIAAANPLFLSEADVDQESLEKEKEIYRAQALNEGKPEHIVDKMVMGRIKKYCK
EVCLLDQAWVKDGDKSIAKLLEEKSKEVGSPITITKFVRFERGEGIEKKEENFAEEVAKMGGK

Sequences:

>Translated_303_residues
MITAKAVKELRERTGAGMMDCKKALTETNGDMEKAVEVLREKGLAAAAKKAGRVAAEGIVKTYVSEDMKKGSIVEINCET
DFVALNEEFVGFAGRVAELVANSNVNTVEELLAEKLDGDKTVQEVLTELIAKIGENMSVRRFERFSVESGLVQSYIHGGG
RIGVMAELACEASSPVLAEVAKDVCMQIAAANPLFLSEADVDQESLEKEKEIYRAQALNEGKPEHIVDKMVMGRIKKYCK
EVCLLDQAWVKDGDKSIAKLLEEKSKEVGSPITITKFVRFERGEGIEKKEENFAEEVAKMGGK
>Mature_303_residues
MITAKAVKELRERTGAGMMDCKKALTETNGDMEKAVEVLREKGLAAAAKKAGRVAAEGIVKTYVSEDMKKGSIVEINCET
DFVALNEEFVGFAGRVAELVANSNVNTVEELLAEKLDGDKTVQEVLTELIAKIGENMSVRRFERFSVESGLVQSYIHGGG
RIGVMAELACEASSPVLAEVAKDVCMQIAAANPLFLSEADVDQESLEKEKEIYRAQALNEGKPEHIVDKMVMGRIKKYCK
EVCLLDQAWVKDGDKSIAKLLEEKSKEVGSPITITKFVRFERGEGIEKKEENFAEEVAKMGGK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=226, Percent_Identity=28.7610619469027, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786366, Length=299, Percent_Identity=45.819397993311, Blast_Score=226, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17561440, Length=310, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921466, Length=317, Percent_Identity=27.7602523659306, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_CLOP1 (Q0TPQ4)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696386.1
- ProteinModelPortal:   Q0TPQ4
- STRING:   Q0TPQ4
- GeneID:   4201938
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1953
- TIGR:   CPF_1953
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   CPER195103:CPF_1953-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 33188; Mature: 33188

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAKAVKELRERTGAGMMDCKKALTETNGDMEKAVEVLREKGLAAAAKKAGRVAAEGIV
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KTYVSEDMKKGSIVEINCETDFVALNEEFVGFAGRVAELVANSNVNTVEELLAEKLDGDK
HHHHHHHHCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
TVQEVLTELIAKIGENMSVRRFERFSVESGLVQSYIHGGGRIGVMAELACEASSPVLAEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHH
AKDVCMQIAAANPLFLSEADVDQESLEKEKEIYRAQALNEGKPEHIVDKMVMGRIKKYCK
HHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EVCLLDQAWVKDGDKSIAKLLEEKSKEVGSPITITKFVRFERGEGIEKKEENFAEEVAKM
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
GGK
CCC
>Mature Secondary Structure
MITAKAVKELRERTGAGMMDCKKALTETNGDMEKAVEVLREKGLAAAAKKAGRVAAEGIV
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KTYVSEDMKKGSIVEINCETDFVALNEEFVGFAGRVAELVANSNVNTVEELLAEKLDGDK
HHHHHHHHCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
TVQEVLTELIAKIGENMSVRRFERFSVESGLVQSYIHGGGRIGVMAELACEASSPVLAEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHH
AKDVCMQIAAANPLFLSEADVDQESLEKEKEIYRAQALNEGKPEHIVDKMVMGRIKKYCK
HHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EVCLLDQAWVKDGDKSIAKLLEEKSKEVGSPITITKFVRFERGEGIEKKEENFAEEVAKM
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
GGK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA