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The map label for this gene is infB

Identifier: 18310668

GI number: 18310668

Start: 1961927

End: 1963966

Strand: Reverse

Name: infB

Synonym: CPE1686

Alternate gene names: 18310668

Gene position: 1963966-1961927 (Counterclockwise)

Preceding gene: 18310669

Following gene: 18310667

Centisome position: 64.79

GC content: 34.12

Gene sequence:

>2040_bases
ATGTCAAAAATAAGAGTTTATGAATTGGCAAAAGAGTTAAGAGTTCCAAGTAAAGTTCTTATAAACGTATTAATGGATGA
GTTCGGCGTTGAGGTTAAAAACCATATGAGCGTTATAGAAGATGAAGATGCTGCGTTAATAAAAGAACTTTTAGCAGGAA
GTGAAGCAAACAGTGAATTGGTTGCTGAATATGAAGCTGAATTAGCTGAAGAAGTTAATAATGCTGCTAAGAAGAAAAAG
AAAAGAAAAAAAGGTAGCGAAGATGATAACTTAGAACAAGACGTTGAAGTTATCGAAATCGGGAAGACTATAACAGTTAA
AGAATTAGCTGAGAAATTAAACAAACCAGTTAATGATGTTATAAAAACTCTTATCTTCACAGGAGTAATGGCTGCTATAA
ACCAAGAAATAGATTTTGAAACAGCTGAAAAGGTTGCTGAAAAATATGAGGTTGCAGTTTATGAAAAAGAAGAAGAGAAC
ACTTTAGAAGAGTTCGAAGAAGAAACTGATGTAGAAGAAGAAAACTTAGCTAAGAGACCACCTATCATAACAGTTATGGG
TCACGTTGACCATGGTAAAACTTCATTACTTGATGCTATAAGAAAATCAAAGGTAACAAGTACAGAGGCTGGTGGAATAA
CTCAACATATAGGTGCTTACACTGTTGAAGTAAACGGAGAAACTTTAACATTCTTAGATACACCAGGACATGAAGCTTTC
ACAGCAATGAGAGCTAGAGGAGCTCAAATAACAGATGTAGTTATCTTAGTTGTTGCAGCTGATGACGGAATAATGCCACA
AACAGTAGAAGCTATAAATCACTGTAAGGCAGCTAACGTTCCAATGATAGTTGCTATAAACAAAATGGATAGAGAAGGTG
CTAATCCAGATAGAGTTAAACAAGAATTAACTGAGCATGGATTAGTTGTTGAAGACTGGGGTGGAGATATAATAGCAGTA
CCAGTTTCAGCTAAAACTAGAGAAAACATAGATACTCTATTAGAAATGGTTCTTTTAACTTCAGAAATGCAAGAATTAAA
AGCAGATGCTGGAAGAAAAGCAAAAGGAACAGTTGTAGAGGCTAAATTAGATAAAGGTAGAGGTGCTGTAGCAACATTAT
TAGTTCAAAATGGTACTCTACACATGGGAGATTCAATCATAGTTGGTAGCACTTACGGAAGAATAAGAGCTATGTTTGAT
GATTCAGGTAAGAAGATAAAATCAGCTGGTCCATCAATTCCAGTTGAGGTTTTAGGTCTTTCAGAAGTACCAGCTGCTGG
AGATAGATTCACAGTTGTTAAAGATGAAAAAACAGCTAGAAACATGGCTGAAGCTAGAAAAGAAAAAATAAGACAAGAAA
GTTTCGCAACTTCACATAGAGTTTCATTAGAAGATTTATATAGCCAAATTAAAGAAGGTTCAGTTAAAGAGCTTTCAGTT
ATAGTTAAAGCAGACGTTCAAGGTTCTGTTGAAGCTATAAAAGCATCATTAGAAAAATTATCAACTGATGATGTAAAGGT
AAGAGTTATACACGGAGCTGTTGGTGCTATATCAGAAACAGATATAACATTAGCTGCTGCATCTAACGCTATAGTAATAG
GATTTAATGTTAGACCAGATAACAATGCCGTAGCAGCTTCAGAGAGAGATGGAGTTGAAGTTAAAACTTACAGAGTAATA
TACGACGCTATAGAAGATATTAAGTCAGCTATGATCGGTATGTTAGATCCAGAATACAAAGAAGTTGTATTAGGAACTGC
TGAAATAAGAGCTACTTACAAAATTTCTAACGTTGGAACAATTGCTGGAGGATATGTATTAACTGGTAAATTAGTTAGAA
ATGCAGATGTAAGAGTTATAAGAGAAGGTATTGTAATATTTGAATCTAAGTTAGCATCATTAAAGAGATTTAAAGATGAT
GTAAAAGAAGTAAATGCTGGATATGAGTGTGGATTTAGTGTAGAAAAGTTCAATGACATTAAAGAAGGCGATATAATAGA
AGCATATACTATGGAAGCTGTTCAAAGAAAAGAACTTTAA

Upstream 100 bases:

>100_bases
AATCAATATATTAGGAGTAACTGATGAGAATATGGCAGAAAAACTTTTGTCATATTCTAATAATAATTAGTTCATCTAAA
AATTTTTCGGGGGTGAATAT

Downstream 100 bases:

>100_bases
TTTTATAAAGAGGTGATTTATATGGCTAACTTCAGAGGTAAAAGAATAAATGAAGAAGTAAGAAAAGAAGTAAGTGATAT
CATAAGAAATCAAATAAAAG

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSELVAEYEAELAEEVNNAAKKKK
KRKKGSEDDNLEQDVEVIEIGKTITVKELAEKLNKPVNDVIKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEEN
TLEEFEEETDVEEENLAKRPPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAF
TAMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVKQELTEHGLVVEDWGGDIIAV
PVSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVEAKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFD
DSGKKIKSAGPSIPVEVLGLSEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSV
IVKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPDNNAVAASERDGVEVKTYRVI
YDAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGTIAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDD
VKEVNAGYECGFSVEKFNDIKEGDIIEAYTMEAVQRKEL

Sequences:

>Translated_679_residues
MSKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSELVAEYEAELAEEVNNAAKKKK
KRKKGSEDDNLEQDVEVIEIGKTITVKELAEKLNKPVNDVIKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEEN
TLEEFEEETDVEEENLAKRPPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAF
TAMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVKQELTEHGLVVEDWGGDIIAV
PVSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVEAKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFD
DSGKKIKSAGPSIPVEVLGLSEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSV
IVKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPDNNAVAASERDGVEVKTYRVI
YDAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGTIAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDD
VKEVNAGYECGFSVEKFNDIKEGDIIEAYTMEAVQRKEL
>Mature_678_residues
SKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSELVAEYEAELAEEVNNAAKKKKK
RKKGSEDDNLEQDVEVIEIGKTITVKELAEKLNKPVNDVIKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEENT
LEEFEEETDVEEENLAKRPPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAFT
AMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVKQELTEHGLVVEDWGGDIIAVP
VSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVEAKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFDD
SGKKIKSAGPSIPVEVLGLSEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSVI
VKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPDNNAVAASERDGVEVKTYRVIY
DAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGTIAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDDV
KEVNAGYECGFSVEKFNDIKEGDIIEAYTMEAVQRKEL

Specific function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 7

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family

Homologues:

Organism=Homo sapiens, GI53729339, Length=641, Percent_Identity=36.5054602184087, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI53729337, Length=641, Percent_Identity=36.5054602184087, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI84043963, Length=510, Percent_Identity=28.2352941176471, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI157426893, Length=250, Percent_Identity=26.8, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789559, Length=580, Percent_Identity=53.9655172413793, Blast_Score=589, Evalue=1e-169,
Organism=Escherichia coli, GI2367247, Length=306, Percent_Identity=29.7385620915033, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788922, Length=230, Percent_Identity=27.8260869565217, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI48994988, Length=133, Percent_Identity=35.3383458646617, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994658, Length=557, Percent_Identity=34.1113105924596, Blast_Score=311, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI212656558, Length=557, Percent_Identity=24.5960502692998, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17557151, Length=216, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324550, Length=614, Percent_Identity=37.1335504885993, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319282, Length=480, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28572034, Length=688, Percent_Identity=36.7732558139535, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24656849, Length=450, Percent_Identity=28.6666666666667, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI160714833, Length=113, Percent_Identity=56.6371681415929, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI78706572, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): IF2_CLOP1 (Q0TPR7)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696373.1
- ProteinModelPortal:   Q0TPR7
- SMR:   Q0TPR7
- STRING:   Q0TPR7
- GeneID:   4203378
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1940
- TIGR:   CPF_1940
- eggNOG:   COG0532
- HOGENOM:   HBG635083
- OMA:   QVINVPK
- ProtClustDB:   PRK05306
- BioCyc:   CPER195103:CPF_1940-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00100_B
- InterPro:   IPR006847
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000178
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000
- Gene3D:   G3DSA:3.40.50.10050
- PANTHER:   PTHR23115:SF41
- TIGRFAMs:   TIGR00487
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; PF04760 IF2_N; SSF52156 TIF_IF2_dom3; SSF50447 Translat_factor

EC number: NA

Molecular weight: Translated: 74161; Mature: 74030

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01176 IF2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSEL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
VAEYEAELAEEVNNAAKKKKKRKKGSEDDNLEQDVEVIEIGKTITVKELAEKLNKPVNDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCEEEHHHHHHHHCCCHHHH
IKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEENTLEEFEEETDVEEENLAKRP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHCCCC
PIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAF
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCEEEEEECCCHHHH
TAMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVK
HHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHH
QELTEHGLVVEDWGGDIIAVPVSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVE
HHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFDDSGKKIKSAGPSIPVEVLGL
EEECCCCCEEEEEEEECCEEEECCEEEEECCCCCEEEEECCCCCCHHCCCCCCCEEEEEC
SEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSV
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHEEE
IVKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPD
EEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEEEEEEECCC
NNAVAASERDGVEVKTYRVIYDAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGT
CCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHEEEEEEECCCCE
IAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDDVKEVNAGYECGFSVEKFNDI
ECCCEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC
KEGDIIEAYTMEAVQRKEL
CCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SKIRVYELAKELRVPSKVLINVLMDEFGVEVKNHMSVIEDEDAALIKELLAGSEANSEL
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
VAEYEAELAEEVNNAAKKKKKRKKGSEDDNLEQDVEVIEIGKTITVKELAEKLNKPVNDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCEEEHHHHHHHHCCCHHHH
IKTLIFTGVMAAINQEIDFETAEKVAEKYEVAVYEKEEENTLEEFEEETDVEEENLAKRP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHCCCC
PIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVEVNGETLTFLDTPGHEAF
CEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCEEEEEECCCHHHH
TAMRARGAQITDVVILVVAADDGIMPQTVEAINHCKAANVPMIVAINKMDREGANPDRVK
HHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHH
QELTEHGLVVEDWGGDIIAVPVSAKTRENIDTLLEMVLLTSEMQELKADAGRKAKGTVVE
HHHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AKLDKGRGAVATLLVQNGTLHMGDSIIVGSTYGRIRAMFDDSGKKIKSAGPSIPVEVLGL
EEECCCCCEEEEEEEECCEEEECCEEEEECCCCCEEEEECCCCCCHHCCCCCCCEEEEEC
SEVPAAGDRFTVVKDEKTARNMAEARKEKIRQESFATSHRVSLEDLYSQIKEGSVKELSV
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHEEE
IVKADVQGSVEAIKASLEKLSTDDVKVRVIHGAVGAISETDITLAAASNAIVIGFNVRPD
EEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEEEEEEECCC
NNAVAASERDGVEVKTYRVIYDAIEDIKSAMIGMLDPEYKEVVLGTAEIRATYKISNVGT
CCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHEEEEEEECCCCE
IAGGYVLTGKLVRNADVRVIREGIVIFESKLASLKRFKDDVKEVNAGYECGFSVEKFNDI
ECCCEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC
KEGDIIEAYTMEAVQRKEL
CCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA