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The map label for this gene is nrnA [H]

Identifier: 18310666

GI number: 18310666

Start: 1960598

End: 1961551

Strand: Reverse

Name: nrnA [H]

Synonym: CPE1684

Alternate gene names: 18310666

Gene position: 1961551-1960598 (Counterclockwise)

Preceding gene: 18310667

Following gene: 18310665

Centisome position: 64.71

GC content: 29.87

Gene sequence:

>954_bases
ATGAGATTTCATGATGTAATATCAATTATAAATAAAAGCAAAAAAATTGGTATAACATATCATGTATCTCCAGATGGTGA
TGCCTTAGGTAGTGTCTTAGCACTACTTCAAGGCATTAGAATTTATGGTAAAGAAGCTTATGTTATCTCTAAAGACCTAG
TCTCAGATAACCTAAGCTTTCTGCCTTATGCTGAGGAAATAACTGGAGAAGTTATAAAGCCATCAGAAGATACTGATTGT
GTTATAGTATTAGATTGTGGAAATGTTGAAAGAATTTCCGCAGATTTAAACGAATTCAAAGGAACTTTAGTTAATATGGA
TCATCATTTATCAAATGATAAATATGGTATTATTAACTATGTAGATACAGAGGCTTCTGCAACAGCTGAAATAATATTTA
TGCTACTTAAGGAGTTAAAGGTTGAAATTAATGAAAATATAGCTAAATGTCTATATACATCATTAATAACTGATACAGGT
TCTTTTAGATACTCAAATTCTACTGAAAGAACTCATATAATAGCAGGGGAATTAGTTAATTATATAAAACATGATGAAAT
TCATAGAAATATATTTGATAATAAGCCTTTTGCTAAAATGAAACTAATGTCTTTAGTTTTAGGAGATATGGAGCTAGTTT
GCAATAATAAAATAGTTCTTATGAGAATTACTAAAGAGATGATAGATTCTATTGGAGAAGAAGTTCAAAATAGTTCAGAT
GTTGTATCCTTAGGAAATCAAATAAAAGGTGTAGAAGGATGCATACTTCTTAAAGAGGTAGATGAGGGAGTAAAGGTTAG
CTTAAGATCTAAAGATACATTAGATGTTAGAAAAATTGCAGAAAACTTTGGTGGCGGTGGTCATACAAAGGCTTCTGGAG
CATTCATTAAAGGTGTAAGTATAGACGAAGCTAAAAATAAAATATTAGAAATACTTGCAAAAGAGATGGTGTAA

Upstream 100 bases:

>100_bases
GCTAAGAAGTACTCCTGAAATATTATTTGAAGAAGATAATTCTATAGATAATGCAATGTATATTGAATCATTGCTAAACA
AAATCAAGGAGAAATAAAAA

Downstream 100 bases:

>100_bases
TATATGAATGGAGTAATTAACATATATAAAAATACGGGAATGACTTCATTTGATGTTGTGGCCATGGTAAGAAGAGTTGC
AAAAATGAAAAAGGTAGGAC

Product: DHH subfamily 1 protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRFHDVISIINKSKKIGITYHVSPDGDALGSVLALLQGIRIYGKEAYVISKDLVSDNLSFLPYAEEITGEVIKPSEDTDC
VIVLDCGNVERISADLNEFKGTLVNMDHHLSNDKYGIINYVDTEASATAEIIFMLLKELKVEINENIAKCLYTSLITDTG
SFRYSNSTERTHIIAGELVNYIKHDEIHRNIFDNKPFAKMKLMSLVLGDMELVCNNKIVLMRITKEMIDSIGEEVQNSSD
VVSLGNQIKGVEGCILLKEVDEGVKVSLRSKDTLDVRKIAENFGGGGHTKASGAFIKGVSIDEAKNKILEILAKEMV

Sequences:

>Translated_317_residues
MRFHDVISIINKSKKIGITYHVSPDGDALGSVLALLQGIRIYGKEAYVISKDLVSDNLSFLPYAEEITGEVIKPSEDTDC
VIVLDCGNVERISADLNEFKGTLVNMDHHLSNDKYGIINYVDTEASATAEIIFMLLKELKVEINENIAKCLYTSLITDTG
SFRYSNSTERTHIIAGELVNYIKHDEIHRNIFDNKPFAKMKLMSLVLGDMELVCNNKIVLMRITKEMIDSIGEEVQNSSD
VVSLGNQIKGVEGCILLKEVDEGVKVSLRSKDTLDVRKIAENFGGGGHTKASGAFIKGVSIDEAKNKILEILAKEMV
>Mature_317_residues
MRFHDVISIINKSKKIGITYHVSPDGDALGSVLALLQGIRIYGKEAYVISKDLVSDNLSFLPYAEEITGEVIKPSEDTDC
VIVLDCGNVERISADLNEFKGTLVNMDHHLSNDKYGIINYVDTEASATAEIIFMLLKELKVEINENIAKCLYTSLITDTG
SFRYSNSTERTHIIAGELVNYIKHDEIHRNIFDNKPFAKMKLMSLVLGDMELVCNNKIVLMRITKEMIDSIGEEVQNSSD
VVSLGNQIKGVEGCILLKEVDEGVKVSLRSKDTLDVRKIAENFGGGGHTKASGAFIKGVSIDEAKNKILEILAKEMV

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35076; Mature: 35076

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHDVISIINKSKKIGITYHVSPDGDALGSVLALLQGIRIYGKEAYVISKDLVSDNLSF
CCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCC
LPYAEEITGEVIKPSEDTDCVIVLDCGNVERISADLNEFKGTLVNMDHHLSNDKYGIINY
CCCHHHHCCCEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECHHHCCCCCEEEEEE
VDTEASATAEIIFMLLKELKVEINENIAKCLYTSLITDTGSFRYSNSTERTHIIAGELVN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEHHHHHHH
YIKHDEIHRNIFDNKPFAKMKLMSLVLGDMELVCNNKIVLMRITKEMIDSIGEEVQNSSD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEECCCEEEEEHHHHHHHHHHHHHCCCCH
VVSLGNQIKGVEGCILLKEVDEGVKVSLRSKDTLDVRKIAENFGGGGHTKASGAFIKGVS
HHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEECCC
IDEAKNKILEILAKEMV
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFHDVISIINKSKKIGITYHVSPDGDALGSVLALLQGIRIYGKEAYVISKDLVSDNLSF
CCHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCC
LPYAEEITGEVIKPSEDTDCVIVLDCGNVERISADLNEFKGTLVNMDHHLSNDKYGIINY
CCCHHHHCCCEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECHHHCCCCCEEEEEE
VDTEASATAEIIFMLLKELKVEINENIAKCLYTSLITDTGSFRYSNSTERTHIIAGELVN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEHHHHHHH
YIKHDEIHRNIFDNKPFAKMKLMSLVLGDMELVCNNKIVLMRITKEMIDSIGEEVQNSSD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEECCCEEEEEHHHHHHHHHHHHHCCCCH
VVSLGNQIKGVEGCILLKEVDEGVKVSLRSKDTLDVRKIAENFGGGGHTKASGAFIKGVS
HHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEECCC
IDEAKNKILEILAKEMV
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]