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The map label for this gene is rbsK [H]

Identifier: 18310614

GI number: 18310614

Start: 1904837

End: 1905769

Strand: Reverse

Name: rbsK [H]

Synonym: CPE1632

Alternate gene names: 18310614

Gene position: 1905769-1904837 (Counterclockwise)

Preceding gene: 18310615

Following gene: 18310613

Centisome position: 62.87

GC content: 29.47

Gene sequence:

>933_bases
ATGAATAAGATATGTGTACTTGGAAGTATGAATATGGATTTAGTTTTAAAGGTTAAAGATATGCCTAAAGTAGGAGAAAC
TATACTCTCTAAGTCATTTCAAAAAATAGCTGGTGGAAAAGGAGCTAATCAAGCAGTAGCAGCTAAAAGAAGTGGCGCAG
AAGTTTTCATGATTTCTAAAATAGGAAAAGATGAAAATGGAAGAGAGTTAAGAGATAAATTAGTAGAAGATAATATAGAT
GTTAAATATGTTTTTGAAGATAGAATAGAGCCAACAGGAATGGCTTTAATAATGGTAAATGATAATGGAAATAATTCAAT
AATTGTTAATGCTGGTTCAAATATGACATTAACAAAAGAGGAAATACATAGTGCTGAAAATTTAATAAAAGAATCAGATA
TTATAATTTCACAATTTGAAACACCAGAGAATATTACAATAGAAGCATTTAAAATAGCTAAGGAAAATGGAAAAGTTACA
ATATTAAATCCAGCTCCAGCTAAAAAAATAAAAGATGAATTATTAAATTACACAGATATAATAGTTCCAAATGAAACAGA
AGCAGAGCTTTTAACTGGAATTGAAATAAAAGATATAGAAGATGCTAAAAAAGCTGGGGATATATTCTTAGGTAAAGGAG
TTAAGTTTGCAATTATTACTCTTGGTGAAAAGGGAGCAGCTTTAATAGGAAAAGATTTTTGTGAAATAGTTCCAGCGTAT
AGAGTTAATGCAATAGATACTACAGCTGCTGGAGATAGCTTCATTGGAGGATTAAGCTCAAAGTTAGATACTAAAAATTT
AGGAAAAGAGACTTTAATTAGCTCCATAAGATTTGGAAATAAGGTATCATCAATAGCAGTACAAAGAAAAGGAGCTCAAC
CATCAATACCATATCTAAAGGAAGTTTTAGAAATTTATAAGGGAGAAGAGTAA

Upstream 100 bases:

>100_bases
TTTTTTATATTTTTACAAAAAAAGTCTTGATTATCGTTTACAAAAGTATTATTATATAGTTAATCGGTTCACTGAATCGG
TTAACTAGGGAGGGATATTA

Downstream 100 bases:

>100_bases
TTATGAGAAAAACAAGCTTATTAAATAGTAACATAAGTTCAGTTATATCAAAGATGGGACACACTGATATGTTGGCTATA
GGGGATTGTGGATTACCTAT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNKICVLGSMNMDLVLKVKDMPKVGETILSKSFQKIAGGKGANQAVAAKRSGAEVFMISKIGKDENGRELRDKLVEDNID
VKYVFEDRIEPTGMALIMVNDNGNNSIIVNAGSNMTLTKEEIHSAENLIKESDIIISQFETPENITIEAFKIAKENGKVT
ILNPAPAKKIKDELLNYTDIIVPNETEAELLTGIEIKDIEDAKKAGDIFLGKGVKFAIITLGEKGAALIGKDFCEIVPAY
RVNAIDTTAAGDSFIGGLSSKLDTKNLGKETLISSIRFGNKVSSIAVQRKGAQPSIPYLKEVLEIYKGEE

Sequences:

>Translated_310_residues
MNKICVLGSMNMDLVLKVKDMPKVGETILSKSFQKIAGGKGANQAVAAKRSGAEVFMISKIGKDENGRELRDKLVEDNID
VKYVFEDRIEPTGMALIMVNDNGNNSIIVNAGSNMTLTKEEIHSAENLIKESDIIISQFETPENITIEAFKIAKENGKVT
ILNPAPAKKIKDELLNYTDIIVPNETEAELLTGIEIKDIEDAKKAGDIFLGKGVKFAIITLGEKGAALIGKDFCEIVPAY
RVNAIDTTAAGDSFIGGLSSKLDTKNLGKETLISSIRFGNKVSSIAVQRKGAQPSIPYLKEVLEIYKGEE
>Mature_310_residues
MNKICVLGSMNMDLVLKVKDMPKVGETILSKSFQKIAGGKGANQAVAAKRSGAEVFMISKIGKDENGRELRDKLVEDNID
VKYVFEDRIEPTGMALIMVNDNGNNSIIVNAGSNMTLTKEEIHSAENLIKESDIIISQFETPENITIEAFKIAKENGKVT
ILNPAPAKKIKDELLNYTDIIVPNETEAELLTGIEIKDIEDAKKAGDIFLGKGVKFAIITLGEKGAALIGKDFCEIVPAY
RVNAIDTTAAGDSFIGGLSSKLDTKNLGKETLISSIRFGNKVSSIAVQRKGAQPSIPYLKEVLEIYKGEE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=36.1204013377926, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI32484973, Length=268, Percent_Identity=29.1044776119403, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI32484975, Length=262, Percent_Identity=29.0076335877863, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=43.3333333333333, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI87081971, Length=297, Percent_Identity=29.96632996633, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082343, Length=297, Percent_Identity=26.5993265993266, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788491, Length=262, Percent_Identity=25.9541984732824, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=38.1107491856677, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=30.1492537313433, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=36.3934426229508, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=33, Blast_Score=164, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33651; Mature: 33651

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKICVLGSMNMDLVLKVKDMPKVGETILSKSFQKIAGGKGANQAVAAKRSGAEVFMISK
CCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEE
IGKDENGRELRDKLVEDNIDVKYVFEDRIEPTGMALIMVNDNGNNSIIVNAGSNMTLTKE
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCEEEHH
EIHSAENLIKESDIIISQFETPENITIEAFKIAKENGKVTILNPAPAKKIKDELLNYTDI
HHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCEEE
IVPNETEAELLTGIEIKDIEDAKKAGDIFLGKGVKFAIITLGEKGAALIGKDFCEIVPAY
EECCCCHHHHHCCCEEECCHHHHHCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCC
RVNAIDTTAAGDSFIGGLSSKLDTKNLGKETLISSIRFGNKVSSIAVQRKGAQPSIPYLK
EECCCCCCCCCCHHHCCHHCCCCHHHCCHHHHHHHHHCCCHHHHHHEECCCCCCCCHHHH
EVLEIYKGEE
HHHHHHCCCC
>Mature Secondary Structure
MNKICVLGSMNMDLVLKVKDMPKVGETILSKSFQKIAGGKGANQAVAAKRSGAEVFMISK
CCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEE
IGKDENGRELRDKLVEDNIDVKYVFEDRIEPTGMALIMVNDNGNNSIIVNAGSNMTLTKE
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCEEEHH
EIHSAENLIKESDIIISQFETPENITIEAFKIAKENGKVTILNPAPAKKIKDELLNYTDI
HHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHCCCEEE
IVPNETEAELLTGIEIKDIEDAKKAGDIFLGKGVKFAIITLGEKGAALIGKDFCEIVPAY
EECCCCHHHHHCCCEEECCHHHHHCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCC
RVNAIDTTAAGDSFIGGLSSKLDTKNLGKETLISSIRFGNKVSSIAVQRKGAQPSIPYLK
EECCCCCCCCCCHHHCCHHCCCCHHHCCHHHHHHHHHCCCHHHHHHEECCCCCCCCHHHH
EVLEIYKGEE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]