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The map label for this gene is yrbG [C]

Identifier: 18310547

GI number: 18310547

Start: 1833988

End: 1834983

Strand: Reverse

Name: yrbG [C]

Synonym: CPE1565

Alternate gene names: 18310547

Gene position: 1834983-1833988 (Counterclockwise)

Preceding gene: 18310548

Following gene: 18310546

Centisome position: 60.53

GC content: 29.42

Gene sequence:

>996_bases
ATGAACTACATATTTCTAATAATAGGGTTCCTTTTACTTATTAAAGGAGCAGATCTTTTTGTTGATGGGGCTTCAGGAAT
AGCTAAAAAGCTAGGAGTTCCAGCTGTTATAATTGGACTTACTATTGTATCCTTAGGAACTAGTGCCCCAGAGCTTGCAG
TAAGTATATCAGCTTCACTAAAAGGTAGCAATGATATTACCATGGGAAATGTTTTAGGATCAAATTTATTTAATCTTTTA
GCAGCTTTAGGATGTACAGCCATTGTGGCTCCTTTAGTCATAAAGAAGCACATAATAAAAAATGATTTTATAGTAAATTT
AATTGCAACTTTTATTTTATATGTTTTTACTTTTACTGGACTAATAGGAAGTAAAAACTCTTTATCTAGAATAGATGGAG
CAGTATTAGTATTAATGTGCATAACATATATAATATATTTAATATATACAGTTAAGAGAAGTAATAAAAGAGAAGGTGAA
GTAGCAGTAACTGCAGAATTTGAAGATTTTGAGGAGCAAAACATAAAGTCACCTAATAGCACAGTTAAAAATATAATTTT
ATCAATAGTTGGAGTTATAGGAATAATATTAGGTGGAAAAATAGTTGTTGATTCAGCCTCTGCAATTGCCTTAGGATTAG
GACTGAGTGAAAAATTAGTTGGTCTTACAATTGTGGCAATAGGTACTTCTCTTCCAGAACTTGTTACTTCTTTAGTGGCA
GCTAAAAAGGGTGAAAATGACATAGCTCTTGGAAATATATTAGGGTCTAATACCTTTAACATATTATTAATATTAGGTTT
ATCATCCGTAATAAGCCCTATAACAATAGCTGCAAGTTTATCAATAGATTTAATATTCCTTATAATTGTTACTTTAATAA
TAGGTGCTTTAATTTTCTTAAATAAGAAAAAAGAAAAAGTACTTACTAGATATGAAGGGGTATTTCTTTTAGCTCTTTAT
ATTGGATATACAGTATATATAATAATGAGAAATTAG

Upstream 100 bases:

>100_bases
TCGATAATATAGAAATTATTTAAATAAATAGTATAATTATACTTATGATTTGTAAAAAATATTTATATTTAATAAAGTTA
CTTGAAATGGAGAGGAATTA

Downstream 100 bases:

>100_bases
TTTTTTTTAACTGTCTTAAATTAAGACAGTTATTTTTTTTTGTGAAATTTAGCATATAGTGTAGACTTTCATTTCAAATA
TTATAGCTAAAAATTAAAAA

Product: hypothetical protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNYIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISASLKGSNDITMGNVLGSNLFNLL
AALGCTAIVAPLVIKKHIIKNDFIVNLIATFILYVFTFTGLIGSKNSLSRIDGAVLVLMCITYIIYLIYTVKRSNKREGE
VAVTAEFEDFEEQNIKSPNSTVKNIILSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVA
AKKGENDIALGNILGSNTFNILLILGLSSVISPITIAASLSIDLIFLIIVTLIIGALIFLNKKKEKVLTRYEGVFLLALY
IGYTVYIIMRN

Sequences:

>Translated_331_residues
MNYIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISASLKGSNDITMGNVLGSNLFNLL
AALGCTAIVAPLVIKKHIIKNDFIVNLIATFILYVFTFTGLIGSKNSLSRIDGAVLVLMCITYIIYLIYTVKRSNKREGE
VAVTAEFEDFEEQNIKSPNSTVKNIILSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVA
AKKGENDIALGNILGSNTFNILLILGLSSVISPITIAASLSIDLIFLIIVTLIIGALIFLNKKKEKVLTRYEGVFLLALY
IGYTVYIIMRN
>Mature_331_residues
MNYIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISASLKGSNDITMGNVLGSNLFNLL
AALGCTAIVAPLVIKKHIIKNDFIVNLIATFILYVFTFTGLIGSKNSLSRIDGAVLVLMCITYIIYLIYTVKRSNKREGE
VAVTAEFEDFEEQNIKSPNSTVKNIILSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVA
AKKGENDIALGNILGSNTFNILLILGLSSVISPITIAASLSIDLIFLIIVTLIIGALIFLNKKKEKVLTRYEGVFLLALY
IGYTVYIIMRN

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300796347, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI9966787, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789587, Length=320, Percent_Identity=34.375, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35046; Mature: 35046

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISASL
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEEC
KGSNDITMGNVLGSNLFNLLAALGCTAIVAPLVIKKHIIKNDFIVNLIATFILYVFTFTG
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGSKNSLSRIDGAVLVLMCITYIIYLIYTVKRSNKREGEVAVTAEFEDFEEQNIKSPNS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHCCCCCCH
TVKNIILSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVA
HHHHHHHHHHHHHHHHHCCEEEEECCCHHHEECCCCHHHHHEEEEHHCCCHHHHHHHHHH
AKKGENDIALGNILGSNTFNILLILGLSSVISPITIAASLSIDLIFLIIVTLIIGALIFL
HCCCCCCEEEEHHHCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKKKEKVLTRYEGVFLLALYIGYTVYIIMRN
CCHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
>Mature Secondary Structure
MNYIFLIIGFLLLIKGADLFVDGASGIAKKLGVPAVIIGLTIVSLGTSAPELAVSISASL
CCHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEEC
KGSNDITMGNVLGSNLFNLLAALGCTAIVAPLVIKKHIIKNDFIVNLIATFILYVFTFTG
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGSKNSLSRIDGAVLVLMCITYIIYLIYTVKRSNKREGEVAVTAEFEDFEEQNIKSPNS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHCCCCCCH
TVKNIILSIVGVIGIILGGKIVVDSASAIALGLGLSEKLVGLTIVAIGTSLPELVTSLVA
HHHHHHHHHHHHHHHHHCCEEEEECCCHHHEECCCCHHHHHEEEEHHCCCHHHHHHHHHH
AKKGENDIALGNILGSNTFNILLILGLSSVISPITIAASLSIDLIFLIIVTLIIGALIFL
HCCCCCCEEEEHHHCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKKKEKVLTRYEGVFLLALYIGYTVYIIMRN
CCHHHHHHHHHHHHHHHHHHHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]