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The map label for this gene is dinP [H]

Identifier: 18310548

GI number: 18310548

Start: 1835113

End: 1836192

Strand: Reverse

Name: dinP [H]

Synonym: CPE1566

Alternate gene names: 18310548

Gene position: 1836192-1835113 (Counterclockwise)

Preceding gene: 18310549

Following gene: 18310547

Centisome position: 60.57

GC content: 30.09

Gene sequence:

>1080_bases
ATGAAAGAGAATAGAAAGATAATTCATATAGATATGGACGCTTTTTATGCATCCATTGAACAAAGAGATAATCCAAAGTA
TAAAGGAAAGCCGTTGATTGTTGGCGGGGATCCTAATAGGAGAGGGGTAGTTGCAACTTGCTCTTATGAAGCAAGGAAAT
ACGGAATACATTCAGCTATGCCTTCTTTAACTGCATATAAATTATGTCCTAAAGCTATTTTTATAAGACCTAGAATGGAG
GTTTATAAAAAAGTTTCTAGACAGGTTATGAATATATTAAATGAATACTCTAATATTGTAGAACCCTTGTCCTTAGATGA
GGCTTTTGTTGATGTAAGTAAAAGCAAAAGGTGCAAAGGGTCTGCAACCTTAATAGCCCTTGAAATAAAGGAGAGAATAT
TTAAAGAAGTAGGTCTTACTGCTTCAGCAGGAGTTTCTTTTAATAAATTTTTAGCGAAGATGGCATCAGATTTTAGAAAA
CCAGATGGTATAACAGTAATAACAGAAGAGAATTCAAAGGATTTTATAAGAAAGCTACCTATAGGAAAATTTTTTGGAGT
TGGAAGAGTAACTAAAAATAAATTAAATAATATAGGGGTATTTAAGGGGGAAGATTTACTTGGATTTTCTGAAAAAGAAC
TTATAGGTATTTTGGGTGACAGGGGCAAGATATTATATGAATTTGCTAGGGGAATAGATAATAGACAAGTAAATCCATAC
AGGATTAGAAAGTCTATAGGTAAAGAAATTACCTTAAGAGAAGACATAGAAGATATAGAGGAAATGATAGAGATTTTAGA
AAAAATATCAGAAAGAGTTAGTGAGAGTTTATGTTTATTAAATAAAAAAGGAAAGACTGTAACCTTAAAGGTAAAGTTTA
ACGATTTTAAACATATAACAAGAAGTATTACTTTAGAACACTTTTTAAAAGAACAGAAGGAAATAATGGAATGCGTAAAA
GATCTTATAAGCATAGTTGATTTTAAAAATAAAAAGGTAAGATTATTAGGAATAACAATATCATCTTTAGAAGAAAATAT
AATAACAGAAGAAAGAGAGCAGTTAAGCTTTGATGTTTAG

Upstream 100 bases:

>100_bases
TTAAATAGATTTATTGTTTAAAACTTATCTTTTATAATATTGGAATTTAAAAAGTCTTAGTGTAAAATTAAAAATGAACA
TATGTTTGCATGGAGGCTTT

Downstream 100 bases:

>100_bases
ACAAATTATTAACTAGATGAAAACAAATTTCGATAATATAGAAATTATTTAAATAAATAGTATAATTATACTTATGATTT
GTAAAAAATATTTATATTTA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAMPSLTAYKLCPKAIFIRPRME
VYKKVSRQVMNILNEYSNIVEPLSLDEAFVDVSKSKRCKGSATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRK
PDGITVITEENSKDFIRKLPIGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPY
RIRKSIGKEITLREDIEDIEEMIEILEKISERVSESLCLLNKKGKTVTLKVKFNDFKHITRSITLEHFLKEQKEIMECVK
DLISIVDFKNKKVRLLGITISSLEENIITEEREQLSFDV

Sequences:

>Translated_359_residues
MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAMPSLTAYKLCPKAIFIRPRME
VYKKVSRQVMNILNEYSNIVEPLSLDEAFVDVSKSKRCKGSATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRK
PDGITVITEENSKDFIRKLPIGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPY
RIRKSIGKEITLREDIEDIEEMIEILEKISERVSESLCLLNKKGKTVTLKVKFNDFKHITRSITLEHFLKEQKEIMECVK
DLISIVDFKNKKVRLLGITISSLEENIITEEREQLSFDV
>Mature_359_residues
MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAMPSLTAYKLCPKAIFIRPRME
VYKKVSRQVMNILNEYSNIVEPLSLDEAFVDVSKSKRCKGSATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRK
PDGITVITEENSKDFIRKLPIGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPY
RIRKSIGKEITLREDIEDIEEMIEILEKISERVSESLCLLNKKGKTVTLKVKFNDFKHITRSITLEHFLKEQKEIMECVK
DLISIVDFKNKKVRLLGITISSLEENIITEEREQLSFDV

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=405, Percent_Identity=27.1604938271605, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI7706681, Length=406, Percent_Identity=27.0935960591133, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI7705344, Length=437, Percent_Identity=27.2311212814645, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI154350220, Length=339, Percent_Identity=29.7935103244838, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI5729982, Length=259, Percent_Identity=27.027027027027, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=40.5633802816901, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787432, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=403, Percent_Identity=30.272952853598, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=297, Percent_Identity=26.9360269360269, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=223, Percent_Identity=32.7354260089686, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=37.3983739837398, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=320, Percent_Identity=24.375, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19923006, Length=406, Percent_Identity=24.8768472906404, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21355641, Length=316, Percent_Identity=27.8481012658228, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=316, Percent_Identity=27.8481012658228, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668444, Length=122, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41025; Mature: 41025

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAM
CCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHC
PSLTAYKLCPKAIFIRPRMEVYKKVSRQVMNILNEYSNIVEPLSLDEAFVDVSKSKRCKG
CCHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRKPDGITVITEENSKDFIRKLP
CEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCC
IGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPY
CHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHCCCCCCCCCHH
RIRKSIGKEITLREDIEDIEEMIEILEKISERVSESLCLLNKKGKTVTLKVKFNDFKHIT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHH
RSITLEHFLKEQKEIMECVKDLISIVDFKNKKVRLLGITISSLEENIITEEREQLSFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAM
CCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHC
PSLTAYKLCPKAIFIRPRMEVYKKVSRQVMNILNEYSNIVEPLSLDEAFVDVSKSKRCKG
CCHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRKPDGITVITEENSKDFIRKLP
CEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCC
IGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPY
CHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHCCCCCCCCCHH
RIRKSIGKEITLREDIEDIEEMIEILEKISERVSESLCLLNKKGKTVTLKVKFNDFKHIT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHH
RSITLEHFLKEQKEIMECVKDLISIVDFKNKKVRLLGITISSLEENIITEEREQLSFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA