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The map label for this gene is macB1 [H]

Identifier: 18310522

GI number: 18310522

Start: 1802968

End: 1804152

Strand: Reverse

Name: macB1 [H]

Synonym: CPE1540

Alternate gene names: 18310522

Gene position: 1804152-1802968 (Counterclockwise)

Preceding gene: 18310523

Following gene: 18310520

Centisome position: 59.51

GC content: 30.04

Gene sequence:

>1185_bases
ATGTCAGCAATTAATTTAATAAAAACAGCCATTGCTAGTTTAAAGTTTCATAAGTTAAGGACTTTTCTAACAATGATTGG
TATTATTATTGGCATAAGCTCTGTAGTTACAATACTTTCAGTTGGAGATGGATTAAAAGCTTATGTTTTAGAATCTTCTC
AAGAAACTAATGCTAATAAGATAAACATAACATTTAAACCAGATAATTTTGATGCTAATATGAGTCTTTTAGAACCTTTT
ACAAAATCAGATATGAATGGAATAAAAGGAATAAAGGGAGTTAAAGATGTGAAGCCATCTCAAGGTTTTATGGGCATAAT
GAGTTTTTCAAGTAGTCAGCTTCAGTATTTTGATAAAAATCAATTTGCTATGCTTGGATCCTATGATGGAAAAAATGAGA
AAGTTGAATATGGAAGATGGTTTGAAGATGGAGATAAGGATAAGTCTGTAATTGTATTAGATAATAATGTTGCAAAAGAA
CTATTTAATCCAATAGAAAGTGGTATTGGTAAGGCTGTAACCATGAATGGAATGAATTTTGAGGTTATAGGTATTTTACC
ACATGTTGATATTATGAGTTTTGGAGGAAATACAAGTTATGTTCCAAAGAAAGCTATAGACAATATGAATAGCAATGAAG
TAATAACTTCCTTAGATGTATCACTTAATGCAGGTGTTGATAAAAAAGAAGTATATAAGGACATAGAAAAATATTTAATG
GCTAACCATCCTAATATTGGAGGGAAATATGAGATGCAAGACCCAGAGGAAGTTACAAAAGCCTTTGAAAAGATAATTGG
TGGATTAACAAAATTCATAGCATTTATTACAGGAATTTCACTTTTAGTAGGTGGAATTGGAGTTATGAATATAATGTATG
TTTCAGTTTCTGAAAGAAAAAGAGAAATTGGTATAAGAAGAGCTATTGGGGCAAAGCCTAAGAGCATATTACTTCAATTC
TTATTTGAAGCTGTATTAGTAACTTTAATAGGTGGATTAATTGGAATATTATTAGGATACTTAATATCCAAAGTAGCTGG
AGCCTTTTTACCATTTAAGCCAATACTTACAATGAGTACCTTTGTAGGAGCTACATTAGTTTCAATAATAGAAGGAGTAG
TATTTGGAATAATACCAGCTTACAATGCTTGTAAGTTAGATCCTATAAAAGCTATTTATAGATAG

Upstream 100 bases:

>100_bases
AATAAGACAATAATCATGGTAACACATGATGAAGACTTAACTAAATACGCAAATAAAATAATAAGAGTTAAGGATGGGGT
TATAACAAAGGGGGAAGATT

Downstream 100 bases:

>100_bases
AGAAGATAAATAGTAATTAATATATAAATTAATCATAAAATATAAAGAAAAAAGATGGAAATTACAAATTAATTTCCATC
TTTTTTTATTAATATTCTTA

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSAINLIKTAIASLKFHKLRTFLTMIGIIIGISSVVTILSVGDGLKAYVLESSQETNANKINITFKPDNFDANMSLLEPF
TKSDMNGIKGIKGVKDVKPSQGFMGIMSFSSSQLQYFDKNQFAMLGSYDGKNEKVEYGRWFEDGDKDKSVIVLDNNVAKE
LFNPIESGIGKAVTMNGMNFEVIGILPHVDIMSFGGNTSYVPKKAIDNMNSNEVITSLDVSLNAGVDKKEVYKDIEKYLM
ANHPNIGGKYEMQDPEEVTKAFEKIIGGLTKFIAFITGISLLVGGIGVMNIMYVSVSERKREIGIRRAIGAKPKSILLQF
LFEAVLVTLIGGLIGILLGYLISKVAGAFLPFKPILTMSTFVGATLVSIIEGVVFGIIPAYNACKLDPIKAIYR

Sequences:

>Translated_394_residues
MSAINLIKTAIASLKFHKLRTFLTMIGIIIGISSVVTILSVGDGLKAYVLESSQETNANKINITFKPDNFDANMSLLEPF
TKSDMNGIKGIKGVKDVKPSQGFMGIMSFSSSQLQYFDKNQFAMLGSYDGKNEKVEYGRWFEDGDKDKSVIVLDNNVAKE
LFNPIESGIGKAVTMNGMNFEVIGILPHVDIMSFGGNTSYVPKKAIDNMNSNEVITSLDVSLNAGVDKKEVYKDIEKYLM
ANHPNIGGKYEMQDPEEVTKAFEKIIGGLTKFIAFITGISLLVGGIGVMNIMYVSVSERKREIGIRRAIGAKPKSILLQF
LFEAVLVTLIGGLIGILLGYLISKVAGAFLPFKPILTMSTFVGATLVSIIEGVVFGIIPAYNACKLDPIKAIYR
>Mature_393_residues
SAINLIKTAIASLKFHKLRTFLTMIGIIIGISSVVTILSVGDGLKAYVLESSQETNANKINITFKPDNFDANMSLLEPFT
KSDMNGIKGIKGVKDVKPSQGFMGIMSFSSSQLQYFDKNQFAMLGSYDGKNEKVEYGRWFEDGDKDKSVIVLDNNVAKEL
FNPIESGIGKAVTMNGMNFEVIGILPHVDIMSFGGNTSYVPKKAIDNMNSNEVITSLDVSLNAGVDKKEVYKDIEKYLMA
NHPNIGGKYEMQDPEEVTKAFEKIIGGLTKFIAFITGISLLVGGIGVMNIMYVSVSERKREIGIRRAIGAKPKSILLQFL
FEAVLVTLIGGLIGILLGYLISKVAGAFLPFKPILTMSTFVGATLVSIIEGVVFGIIPAYNACKLDPIKAIYR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=404, Percent_Identity=33.6633663366337, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42992; Mature: 42861

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAINLIKTAIASLKFHKLRTFLTMIGIIIGISSVVTILSVGDGLKAYVLESSQETNANK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCE
INITFKPDNFDANMSLLEPFTKSDMNGIKGIKGVKDVKPSQGFMGIMSFSSSQLQYFDKN
EEEEECCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCC
QFAMLGSYDGKNEKVEYGRWFEDGDKDKSVIVLDNNVAKELFNPIESGIGKAVTMNGMNF
CEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCE
EVIGILPHVDIMSFGGNTSYVPKKAIDNMNSNEVITSLDVSLNAGVDKKEVYKDIEKYLM
EEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECEECCCCCHHHHHHHHHHHHH
ANHPNIGGKYEMQDPEEVTKAFEKIIGGLTKFIAFITGISLLVGGIGVMNIMYVSVSERK
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHH
REIGIRRAIGAKPKSILLQFLFEAVLVTLIGGLIGILLGYLISKVAGAFLPFKPILTMST
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FVGATLVSIIEGVVFGIIPAYNACKLDPIKAIYR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
SAINLIKTAIASLKFHKLRTFLTMIGIIIGISSVVTILSVGDGLKAYVLESSQETNANK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCE
INITFKPDNFDANMSLLEPFTKSDMNGIKGIKGVKDVKPSQGFMGIMSFSSSQLQYFDKN
EEEEECCCCCCCCHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCC
QFAMLGSYDGKNEKVEYGRWFEDGDKDKSVIVLDNNVAKELFNPIESGIGKAVTMNGMNF
CEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCE
EVIGILPHVDIMSFGGNTSYVPKKAIDNMNSNEVITSLDVSLNAGVDKKEVYKDIEKYLM
EEEEECCCCEEEECCCCCCCCCHHHHCCCCCCCEEEEEECEECCCCCHHHHHHHHHHHHH
ANHPNIGGKYEMQDPEEVTKAFEKIIGGLTKFIAFITGISLLVGGIGVMNIMYVSVSERK
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHH
REIGIRRAIGAKPKSILLQFLFEAVLVTLIGGLIGILLGYLISKVAGAFLPFKPILTMST
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FVGATLVSIIEGVVFGIIPAYNACKLDPIKAIYR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA