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The map label for this gene is ykpA [H]

Identifier: 18310488

GI number: 18310488

Start: 1758696

End: 1760279

Strand: Direct

Name: ykpA [H]

Synonym: CPE1506

Alternate gene names: 18310488

Gene position: 1758696-1760279 (Clockwise)

Preceding gene: 18310479

Following gene: 18310502

Centisome position: 58.02

GC content: 32.26

Gene sequence:

>1584_bases
ATGATTACAGTAAATAATGTAAGCTTAAGATTTGGTGGAAGAAAACTTTTTGAAGATGTTAACTTAAAGTTTACTCCTGG
AAATTGCTATGGGGTTATTGGCGCAAATGGTGCTGGTAAATCTACATTTTTAAAAATATTAGCTGGTGAAATAGAACCTA
ATACAGGAGAAGTTTCAATTCCTGCTAAAACTAGAGTTTCTGTTTTAAAACAGGATCATTATCAATATGATGATTGTGAA
GTTTTAAAAACAGTTATAATGGGAAATCCAAGATTATTTGAAATAATGGAAGAAAAAGATGCTTTATATGCAAAGCCTGA
TTTTTCTGATGAAGATGGAATAAAAGCTGCTGAACTTGAAGCAGAATTTGCAGATTTAGATGGATGGGAAGCAGAATCAG
AAGCTTCTTCATTACTTCAAGGCTTAGGAATAGGTACTGAGCTTCACTATAGCCATGTTAGAGACCTTAAAGGTGATGAG
AAGGTTAAAGTTCTTTTAGCTCAAGCCTTATTTGGTAAGCCAGATGTACTTATCCTTGACGAGCCTACAAACCACTTAGA
CATAAAAGCTATCACTTGGCTTGAAAACTTCTTAGGAAACTTTGAAGGTACAGTTATAGTTGTATCCCATGATAGACATT
TCTTAAACATGGTTTGTACACAAATATGTGATGTTGACTTTGGAAAAATCAAATTATACGTTGGTAACTATGATTTCTGG
TATGAATCAAGTCAACTTGCACTTCAAATGGCTAAAGACCAAAACAAGAAAAAAGAAGAAAAAATTAAAGAACTTCAAAA
CTTCATTGCTAGATTCAGTGCTAATGCTTCTAAATCTAAGCAAGCTACTTCTCGTAAGAAGTTATTAGATAAGATTACTT
TAGATGATATTCAACCTTCAAGCAGAAAATATCCTTTCGTTGGATTTAAGCCTGAAAGAGAAGTTGGAAACGACATTCTA
GAGGTTAATGGAATATCAAAAACTGTTGATGGAGTTAAACTTCTAGACAATGTAAGTTTCAGAGTTAACAAAGATGATAA
GATTGCCTTTGTTGGAAATGAAAGATCAATAACTACTTTATTTAAAATAATAAATGGAGAAATGGAACCAGATTCAGGAG
ATTATAAGTGGGGCGTAACTATAACTAATGCTTACTTCCCTAAAGATAATACTGAATTCTTTGAGAATTGCGAATTAAAC
TTAGTTGATTGGCTTAGACAATTCTCTGATGAAAAATCTGAATCTTACTTAAGAGGATTCTTAGGAAGAATGTTATTCTC
AGGTGAAGAAGCTCTTAAACAAGCTTCTGTATTATCAGGAGGAGAAAAGGTTAGATGTATGCTTTCTAAATTAATGCTTA
GCTCAGCTAACGTTTTAACTTTAGACCAACCAACTAACCACTTAGACTTAGAATCAATAACAGCAGTAAACAATGGTTTA
GCAGATTATAAGAGCGTATTATTATTTGCTTGTCACGACCACCAATTTGTTGAAACTATAGCAAACAGAATCATAGAATT
AACTCCAGAAGGAATTAAATTTGATAAAGTTTGCACATATGATGAATATTTAGAAACTAAGTAA

Upstream 100 bases:

>100_bases
TTTTGTCGCATTTTATGTTATAATAAGTATTCATGTGCATAAAAATAGTTTTTTTGCATTAACAAATTATTAAAATTTAA
AGAAGAAAGGACAGAACTTA

Downstream 100 bases:

>100_bases
TAAAAAGAGCGTGTGTTGAAATTTTTATTTCAATACACGCTCTCTTCATTTTATACATTAGCATCACTTATGGTTTTAAA
CTCATACCCTTCTTCTTTAT

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MITVNNVSLRFGGRKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILAGEIEPNTGEVSIPAKTRVSVLKQDHYQYDDCE
VLKTVIMGNPRLFEIMEEKDALYAKPDFSDEDGIKAAELEAEFADLDGWEAESEASSLLQGLGIGTELHYSHVRDLKGDE
KVKVLLAQALFGKPDVLILDEPTNHLDIKAITWLENFLGNFEGTVIVVSHDRHFLNMVCTQICDVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQNFIARFSANASKSKQATSRKKLLDKITLDDIQPSSRKYPFVGFKPEREVGNDIL
EVNGISKTVDGVKLLDNVSFRVNKDDKIAFVGNERSITTLFKIINGEMEPDSGDYKWGVTITNAYFPKDNTEFFENCELN
LVDWLRQFSDEKSESYLRGFLGRMLFSGEEALKQASVLSGGEKVRCMLSKLMLSSANVLTLDQPTNHLDLESITAVNNGL
ADYKSVLLFACHDHQFVETIANRIIELTPEGIKFDKVCTYDEYLETK

Sequences:

>Translated_527_residues
MITVNNVSLRFGGRKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILAGEIEPNTGEVSIPAKTRVSVLKQDHYQYDDCE
VLKTVIMGNPRLFEIMEEKDALYAKPDFSDEDGIKAAELEAEFADLDGWEAESEASSLLQGLGIGTELHYSHVRDLKGDE
KVKVLLAQALFGKPDVLILDEPTNHLDIKAITWLENFLGNFEGTVIVVSHDRHFLNMVCTQICDVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQNFIARFSANASKSKQATSRKKLLDKITLDDIQPSSRKYPFVGFKPEREVGNDIL
EVNGISKTVDGVKLLDNVSFRVNKDDKIAFVGNERSITTLFKIINGEMEPDSGDYKWGVTITNAYFPKDNTEFFENCELN
LVDWLRQFSDEKSESYLRGFLGRMLFSGEEALKQASVLSGGEKVRCMLSKLMLSSANVLTLDQPTNHLDLESITAVNNGL
ADYKSVLLFACHDHQFVETIANRIIELTPEGIKFDKVCTYDEYLETK
>Mature_527_residues
MITVNNVSLRFGGRKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILAGEIEPNTGEVSIPAKTRVSVLKQDHYQYDDCE
VLKTVIMGNPRLFEIMEEKDALYAKPDFSDEDGIKAAELEAEFADLDGWEAESEASSLLQGLGIGTELHYSHVRDLKGDE
KVKVLLAQALFGKPDVLILDEPTNHLDIKAITWLENFLGNFEGTVIVVSHDRHFLNMVCTQICDVDFGKIKLYVGNYDFW
YESSQLALQMAKDQNKKKEEKIKELQNFIARFSANASKSKQATSRKKLLDKITLDDIQPSSRKYPFVGFKPEREVGNDIL
EVNGISKTVDGVKLLDNVSFRVNKDDKIAFVGNERSITTLFKIINGEMEPDSGDYKWGVTITNAYFPKDNTEFFENCELN
LVDWLRQFSDEKSESYLRGFLGRMLFSGEEALKQASVLSGGEKVRCMLSKLMLSSANVLTLDQPTNHLDLESITAVNNGL
ADYKSVLLFACHDHQFVETIANRIIELTPEGIKFDKVCTYDEYLETK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=517, Percent_Identity=30.174081237911, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=29.8701298701299, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=29.8701298701299, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI10947135, Length=532, Percent_Identity=27.6315789473684, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI69354671, Length=532, Percent_Identity=27.6315789473684, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI105990541, Length=200, Percent_Identity=27.5, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=44.9905482041588, Blast_Score=493, Evalue=1e-140,
Organism=Escherichia coli, GI1789751, Length=508, Percent_Identity=31.6929133858268, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI2367384, Length=527, Percent_Identity=31.4990512333966, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1787182, Length=503, Percent_Identity=29.4234592445328, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=25.3218884120172, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=238, Percent_Identity=23.9495798319328, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=520, Percent_Identity=30.5769230769231, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17555318, Length=538, Percent_Identity=26.5799256505576, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17559834, Length=523, Percent_Identity=28.8718929254302, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17558664, Length=218, Percent_Identity=28.8990825688073, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=214, Percent_Identity=26.6355140186916, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=523, Percent_Identity=32.6959847036329, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=29.2682926829268, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6325030, Length=237, Percent_Identity=30.8016877637131, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=380, Percent_Identity=24.2105263157895, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6323278, Length=368, Percent_Identity=25.2717391304348, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666836, Length=511, Percent_Identity=30.1369863013699, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24642252, Length=548, Percent_Identity=27.9197080291971, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI18859989, Length=548, Percent_Identity=27.9197080291971, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24641342, Length=512, Percent_Identity=30.078125, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24641565, Length=265, Percent_Identity=23.7735849056604, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59305; Mature: 59305

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVNNVSLRFGGRKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILAGEIEPNTGEVSI
CEEEEEEEEEECCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEC
PAKTRVSVLKQDHYQYDDCEVLKTVIMGNPRLFEIMEEKDALYAKPDFSDEDGIKAAELE
CHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEHHHHCCCEEECCCCCCCCCCEEEECC
AEFADLDGWEAESEASSLLQGLGIGTELHYSHVRDLKGDEKVKVLLAQALFGKPDVLILD
HHHHCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIKAITWLENFLGNFEGTVIVVSHDRHFLNMVCTQICDVDFGKIKLYVGNYDFW
CCCCCEEEHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQNFIARFSANASKSKQATSRKKLLDKITLDDIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SRKYPFVGFKPEREVGNDILEVNGISKTVDGVKLLDNVSFRVNKDDKIAFVGNERSITTL
CCCCCEECCCCCHHHCCCEEEECCCHHHHHHHHHHHCCEEEECCCCEEEEECCCCHHHHH
FKIINGEMEPDSGDYKWGVTITNAYFPKDNTEFFENCELNLVDWLRQFSDEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
LGRMLFSGEEALKQASVLSGGEKVRCMLSKLMLSSANVLTLDQPTNHLDLESITAVNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCH
ADYKSVLLFACHDHQFVETIANRIIELTPEGIKFDKVCTYDEYLETK
HHHHHEEEEEECCHHHHHHHHHHHEECCCCCCCCCCEECHHHHHCCC
>Mature Secondary Structure
MITVNNVSLRFGGRKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILAGEIEPNTGEVSI
CEEEEEEEEEECCHHHHHCCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEC
PAKTRVSVLKQDHYQYDDCEVLKTVIMGNPRLFEIMEEKDALYAKPDFSDEDGIKAAELE
CHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEHHHHCCCEEECCCCCCCCCCEEEECC
AEFADLDGWEAESEASSLLQGLGIGTELHYSHVRDLKGDEKVKVLLAQALFGKPDVLILD
HHHHCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIKAITWLENFLGNFEGTVIVVSHDRHFLNMVCTQICDVDFGKIKLYVGNYDFW
CCCCCEEEHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEE
YESSQLALQMAKDQNKKKEEKIKELQNFIARFSANASKSKQATSRKKLLDKITLDDIQPS
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SRKYPFVGFKPEREVGNDILEVNGISKTVDGVKLLDNVSFRVNKDDKIAFVGNERSITTL
CCCCCEECCCCCHHHCCCEEEECCCHHHHHHHHHHHCCEEEECCCCEEEEECCCCHHHHH
FKIINGEMEPDSGDYKWGVTITNAYFPKDNTEFFENCELNLVDWLRQFSDEKSESYLRGF
HHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
LGRMLFSGEEALKQASVLSGGEKVRCMLSKLMLSSANVLTLDQPTNHLDLESITAVNNGL
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCH
ADYKSVLLFACHDHQFVETIANRIIELTPEGIKFDKVCTYDEYLETK
HHHHHEEEEEECCHHHHHHHHHHHEECCCCCCCCCCEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]