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The map label for this gene is hlyC [C]

Identifier: 18310456

GI number: 18310456

Start: 1730973

End: 1731620

Strand: Direct

Name: hlyC [C]

Synonym: CPE1474

Alternate gene names: 18310456

Gene position: 1730973-1731620 (Clockwise)

Preceding gene: 18310452

Following gene: 18310459

Centisome position: 57.1

GC content: 27.93

Gene sequence:

>648_bases
ATGAAAAATACGTTTTTTAGAGAACCAATAAATGGTTTTACTCATTTATTTGGTGCTATTTTATCAATATTCGCCTTAGT
GGCACTAACAGCTAAAGCTACTTATATATACGGGATTGGATTACCACTTTTATCAGTTATTCTATTTGGTTTTTCATTAG
TGTTGCTTTATAGTGCTTCTGCTATATACCATTTAGTTAATGCAAAGGAAAAAACTATAGCATTTTTAAGACGTTTAGAC
CATTCTATGATCTTTATACTTATCTGCGGAAGTTATATGCCTTATTGTCTTATTGGTCTTGAAGGTAAAGCTCAAATTTT
TATAACTTCTTTAATAGTAATTCTTACGGTTTTAGGTATTTTATTTAAGATGGTTTGGTTTAATTGTCCTAGAATTCTTT
CTACTCTTATGTATATAGGAATGGGATGGATTTCTTTAGGTGCTATTCCATTTTTCAAAAACATACCTGCTTTAGCATTA
ATTTGGTTAGCAATAGGTGGAGTTATATATACAATTGGTGGAATAATTTATGCACTTAAACCAAAATTTCTTGAATTTAA
TAACTTAGGATTTCATGAAATATTTCATATATTCATATTATTAGGAAGCCTATGTCACTTTATATCAATTTTCTTTTATC
TACTATAA

Upstream 100 bases:

>100_bases
AATTTAAAGGTTGATATATTCCTATATTTAAAGGATAATTGTAATATGATAGTAAGTAGTTTCGAAAACTACTTGAAAAC
TTTTTCCTTGGAGGTATGTT

Downstream 100 bases:

>100_bases
AAGAAAAGAAAGGATAGTAATACTAAAAAATAAGTATTACTATCCTTTTTTTATATATCTGAACTTTTAATTTTATCTAT
AAATATTTCTAAGTTTTTAG

Product: hemolysin III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKNTFFREPINGFTHLFGAILSIFALVALTAKATYIYGIGLPLLSVILFGFSLVLLYSASAIYHLVNAKEKTIAFLRRLD
HSMIFILICGSYMPYCLIGLEGKAQIFITSLIVILTVLGILFKMVWFNCPRILSTLMYIGMGWISLGAIPFFKNIPALAL
IWLAIGGVIYTIGGIIYALKPKFLEFNNLGFHEIFHIFILLGSLCHFISIFFYLL

Sequences:

>Translated_215_residues
MKNTFFREPINGFTHLFGAILSIFALVALTAKATYIYGIGLPLLSVILFGFSLVLLYSASAIYHLVNAKEKTIAFLRRLD
HSMIFILICGSYMPYCLIGLEGKAQIFITSLIVILTVLGILFKMVWFNCPRILSTLMYIGMGWISLGAIPFFKNIPALAL
IWLAIGGVIYTIGGIIYALKPKFLEFNNLGFHEIFHIFILLGSLCHFISIFFYLL
>Mature_215_residues
MKNTFFREPINGFTHLFGAILSIFALVALTAKATYIYGIGLPLLSVILFGFSLVLLYSASAIYHLVNAKEKTIAFLRRLD
HSMIFILICGSYMPYCLIGLEGKAQIFITSLIVILTVLGILFKMVWFNCPRILSTLMYIGMGWISLGAIPFFKNIPALAL
IWLAIGGVIYTIGGIIYALKPKFLEFNNLGFHEIFHIFILLGSLCHFISIFFYLL

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Escherichia coli, GI1789266, Length=212, Percent_Identity=34.4339622641509, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 24151; Mature: 24151

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTFFREPINGFTHLFGAILSIFALVALTAKATYIYGIGLPLLSVILFGFSLVLLYSAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIYHLVNAKEKTIAFLRRLDHSMIFILICGSYMPYCLIGLEGKAQIFITSLIVILTVLGI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHH
LFKMVWFNCPRILSTLMYIGMGWISLGAIPFFKNIPALALIWLAIGGVIYTIGGIIYALK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PKFLEFNNLGFHEIFHIFILLGSLCHFISIFFYLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKNTFFREPINGFTHLFGAILSIFALVALTAKATYIYGIGLPLLSVILFGFSLVLLYSAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIYHLVNAKEKTIAFLRRLDHSMIFILICGSYMPYCLIGLEGKAQIFITSLIVILTVLGI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHH
LFKMVWFNCPRILSTLMYIGMGWISLGAIPFFKNIPALALIWLAIGGVIYTIGGIIYALK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
PKFLEFNNLGFHEIFHIFILLGSLCHFISIFFYLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]