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The map label for this gene is dut [H]

Identifier: 18310453

GI number: 18310453

Start: 1728905

End: 1729369

Strand: Reverse

Name: dut [H]

Synonym: CPE1471

Alternate gene names: 18310453

Gene position: 1729369-1728905 (Counterclockwise)

Preceding gene: 18310454

Following gene: 18310451

Centisome position: 57.05

GC content: 33.55

Gene sequence:

>465_bases
ATGATAATTAGAATTAAGTATTTTGATAACGCAACTAAATTAAAAAAAATAACAAAGGGTAATTGGATAGATGTATATGC
TAATAAGGATGTATTTGTTAAATGTGGAGAGAGAGCAATGGTACCTTTAGGATTTGCTTTAGAACTTCCAGAAGGATGGG
AAGGACATTTAGCACCTAGAAGTTCAACTTTTAAAACTTGGGGAATTATACAAACTAATAGTGTTGGCGTTGTAGATGAT
ACATATATAGGAGATAATGATCAGTGGCATATGCCTGTTTATTGCTTACAGGGAAAAGACATTGAAAGTGAGAATGGGGA
AGAAGTTAAAGGAACTTGGATAAGAAAAGGGGATAAAATAGGTCAATTTAGAATTATGGAGGTTATGCCAGAAATAGAGT
TTGAAGAGGTAGAATCCTTTGGAAACAAAGATCGTGGTGGATTTGGTACTACAGGAACAAAATAG

Upstream 100 bases:

>100_bases
TCTGTGGGCTTTAATTTTTAGAAATAAAATTATATAATAGCTATAGTTTAATTTTATTTCTAAAAAATTATATAGATTAA
ACAAAAGAAAGGAATTTGAT

Downstream 100 bases:

>100_bases
ATAAATAAAGAAATAGTGTATTAAAATAACTTTAAGAAATTTATTTTAATACACTATTTTCTTTAAGTTCAATTTAAAAG
AGAATACATGGGAAATTTTT

Product: deoxyuridine 5'-triphosphate nucleotidohydrolase

Products: NA

Alternate protein names: dUTPase; dUTP pyrophosphatase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIIRIKYFDNATKLKKITKGNWIDVYANKDVFVKCGERAMVPLGFALELPEGWEGHLAPRSSTFKTWGIIQTNSVGVVDD
TYIGDNDQWHMPVYCLQGKDIESENGEEVKGTWIRKGDKIGQFRIMEVMPEIEFEEVESFGNKDRGGFGTTGTK

Sequences:

>Translated_154_residues
MIIRIKYFDNATKLKKITKGNWIDVYANKDVFVKCGERAMVPLGFALELPEGWEGHLAPRSSTFKTWGIIQTNSVGVVDD
TYIGDNDQWHMPVYCLQGKDIESENGEEVKGTWIRKGDKIGQFRIMEVMPEIEFEEVESFGNKDRGGFGTTGTK
>Mature_154_residues
MIIRIKYFDNATKLKKITKGNWIDVYANKDVFVKCGERAMVPLGFALELPEGWEGHLAPRSSTFKTWGIIQTNSVGVVDD
TYIGDNDQWHMPVYCLQGKDIESENGEEVKGTWIRKGDKIGQFRIMEVMPEIEFEEVESFGNKDRGGFGTTGTK

Specific function: This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [H]

COG id: COG0756

COG function: function code F; dUTPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dUTPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008180 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.6.1.23 [H]

Molecular weight: Translated: 17472; Mature: 17472

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRIKYFDNATKLKKITKGNWIDVYANKDVFVKCGERAMVPLGFALELPEGWEGHLAPR
CEEEEEECCCCHHHHHHCCCCEEEEEECCEEEEEECCCEEEEEEEEEECCCCCCCCCCCC
SSTFKTWGIIQTNSVGVVDDTYIGDNDQWHMPVYCLQGKDIESENGEEVKGTWIRKGDKI
CCCEEEEEEEEECCCCCEECCEECCCCCEECCEEEECCCCCCCCCCCEEEEEEEECCCCC
GQFRIMEVMPEIEFEEVESFGNKDRGGFGTTGTK
CCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIRIKYFDNATKLKKITKGNWIDVYANKDVFVKCGERAMVPLGFALELPEGWEGHLAPR
CEEEEEECCCCHHHHHHCCCCEEEEEECCEEEEEECCCEEEEEEEEEECCCCCCCCCCCC
SSTFKTWGIIQTNSVGVVDDTYIGDNDQWHMPVYCLQGKDIESENGEEVKGTWIRKGDKI
CCCEEEEEEEEECCCCCEECCEECCCCCEECCEEEECCCCCCCCCCCEEEEEEEECCCCC
GQFRIMEVMPEIEFEEVESFGNKDRGGFGTTGTK
CCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]