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The map label for this gene is furR [H]

Identifier: 18310444

GI number: 18310444

Start: 1719499

End: 1719909

Strand: Reverse

Name: furR [H]

Synonym: CPE1462

Alternate gene names: 18310444

Gene position: 1719909-1719499 (Counterclockwise)

Preceding gene: 18310445

Following gene: 18310443

Centisome position: 56.74

GC content: 25.55

Gene sequence:

>411_bases
ATGGAAGTAAAAGAAATATTTAAAGCTAATGGTGTTAAAGTTACCAAAGCTAGATTATTAATATATGATTTGTTAAAGGA
AAGTGATAGAAGTGTTACTGCCGATTATATATATAGTAAATGTAAAGAGATAAATTTATCTACTGTTTATAGAACTCTAG
AGGTATTTTTAGAGAAGGATTTAGTGGATAAGTTTGAATTAGGAGATGGAAAAAGTTCTTATAAATTAAAGAATAGAAAT
ATTCATAAGCATATTTTAGAATGTGATTTATGTCATAAAGAAATAGAAGTTCCATGTCCTATGCAACAGATTGAGGAGCT
TTTAAGAAATCAAACAGGATTTAAAGTAAAAGAGCATAATCTTACTTTAAAGGGTATATGTGAAGAGTGTATAAATAATA
AGAAAAAATAA

Upstream 100 bases:

>100_bases
AGATCAGTTTAATACTCCAATTTAGAAATATATTTTATACAAGTTTTTTTATGTGATATAATTTATATTAATGATTTAAA
TATTTGTTTAGGAGATTGTT

Downstream 100 bases:

>100_bases
TTTTAAAATAGAATATTTACTTCAAAATTATAAGTATATGAAAATTTATAATTTTGATATTTTATTTATAATTAATACTA
GATTAAATAATAAATTATAG

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MEVKEIFKANGVKVTKARLLIYDLLKESDRSVTADYIYSKCKEINLSTVYRTLEVFLEKDLVDKFELGDGKSSYKLKNRN
IHKHILECDLCHKEIEVPCPMQQIEELLRNQTGFKVKEHNLTLKGICEECINNKKK

Sequences:

>Translated_136_residues
MEVKEIFKANGVKVTKARLLIYDLLKESDRSVTADYIYSKCKEINLSTVYRTLEVFLEKDLVDKFELGDGKSSYKLKNRN
IHKHILECDLCHKEIEVPCPMQQIEELLRNQTGFKVKEHNLTLKGICEECINNKKK
>Mature_136_residues
MEVKEIFKANGVKVTKARLLIYDLLKESDRSVTADYIYSKCKEINLSTVYRTLEVFLEKDLVDKFELGDGKSSYKLKNRN
IHKHILECDLCHKEIEVPCPMQQIEELLRNQTGFKVKEHNLTLKGICEECINNKKK

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15893; Mature: 15893

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKEIFKANGVKVTKARLLIYDLLKESDRSVTADYIYSKCKEINLSTVYRTLEVFLEKD
CCHHHHHHCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LVDKFELGDGKSSYKLKNRNIHKHILECDLCHKEIEVPCPMQQIEELLRNQTGFKVKEHN
HHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCC
LTLKGICEECINNKKK
CHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEVKEIFKANGVKVTKARLLIYDLLKESDRSVTADYIYSKCKEINLSTVYRTLEVFLEKD
CCHHHHHHCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LVDKFELGDGKSSYKLKNRNIHKHILECDLCHKEIEVPCPMQQIEELLRNQTGFKVKEHN
HHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCC
LTLKGICEECINNKKK
CHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]