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The map label for this gene is 18310418

Identifier: 18310418

GI number: 18310418

Start: 1693933

End: 1694595

Strand: Reverse

Name: 18310418

Synonym: CPE1436

Alternate gene names: NA

Gene position: 1694595-1693933 (Counterclockwise)

Preceding gene: 18310419

Following gene: 18310417

Centisome position: 55.9

GC content: 26.4

Gene sequence:

>663_bases
TTGTGCAGAAATAATAGAGAAGATATTTTTAACTTAGTACCAATAAACATTATAAGTAGTAAATTTCATGTTAAGGTCAT
AGGTGGAGGAAAAGCAGCCACCATAAAGGTTAAAGGATTATTAGAAAAAGGTTGTTATGTACATATTTTATCTAAGGAGT
TTTCAAAGGAAATCTTAGATATTGAAAATAAAAATTTAAAACTTGAAAAGGGAAACTATTATAAAGAGTTTATAAAAGAT
GCTCATCTTATAATAATAGCTGTGAATGAAAGTTCTCTAGTATATAAGATAAGCAAGGATTGTGAGAAAGAATATAAACT
ATATTTAAATGCAGCTAATTATAAAGAGGGTATGGTAGCTATTCCTTACAGTAGATGTTATGAGAATCTAGGCTTTAGTA
TAAGCAGTAAATTAGGATCGCCTAGAATAACTAGGGCTATAGGAGAAGAAGTATCAAATATTATTAAGGAAAATGACATA
TACTCAATTAAGGTAGCTAAGATTAGAGAAAAAGCTAAAAAAGAAGAGTTAAAGGATAATATAATAGAGATTATTTCAAG
TAAAGAATTTAAAAATGCCATTTTAGAAAAAAGAGAATATGAATACTTAAAAAATCTTTTAGGAGAAGAATTAGCTAATT
CATTAACTTTAGGATTAAAGTAA

Upstream 100 bases:

>100_bases
CTAAATTAGCAGAAAGAATGATAAAAAGTACAGCTGATGCTTATGTTAATAGGGCAATAGAACTTTTAAAAAGTGAAGCC
TTAAAGGGAAGTGATAGTTC

Downstream 100 bases:

>100_bases
TTATAACAGAATTTTTTATGAAAATATAAAAATAATCAAAATGTGAGGTTTGGATTAATGGAATTAATAATAGCGACTAG
AAAAAGTAAGTTAGCACAAG

Product: precorrin-2 dehydrogenase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MCRNNREDIFNLVPINIISSKFHVKVIGGGKAATIKVKGLLEKGCYVHILSKEFSKEILDIENKNLKLEKGNYYKEFIKD
AHLIIIAVNESSLVYKISKDCEKEYKLYLNAANYKEGMVAIPYSRCYENLGFSISSKLGSPRITRAIGEEVSNIIKENDI
YSIKVAKIREKAKKEELKDNIIEIISSKEFKNAILEKREYEYLKNLLGEELANSLTLGLK

Sequences:

>Translated_220_residues
MCRNNREDIFNLVPINIISSKFHVKVIGGGKAATIKVKGLLEKGCYVHILSKEFSKEILDIENKNLKLEKGNYYKEFIKD
AHLIIIAVNESSLVYKISKDCEKEYKLYLNAANYKEGMVAIPYSRCYENLGFSISSKLGSPRITRAIGEEVSNIIKENDI
YSIKVAKIREKAKKEELKDNIIEIISSKEFKNAILEKREYEYLKNLLGEELANSLTLGLK
>Mature_220_residues
MCRNNREDIFNLVPINIISSKFHVKVIGGGKAATIKVKGLLEKGCYVHILSKEFSKEILDIENKNLKLEKGNYYKEFIKD
AHLIIIAVNESSLVYKISKDCEKEYKLYLNAANYKEGMVAIPYSRCYENLGFSISSKLGSPRITRAIGEEVSNIIKENDI
YSIKVAKIREKAKKEELKDNIIEIISSKEFKNAILEKREYEYLKNLLGEELANSLTLGLK

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 25133; Mature: 25133

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRNNREDIFNLVPINIISSKFHVKVIGGGKAATIKVKGLLEKGCYVHILSKEFSKEILD
CCCCCCCHHHHEECCEEECCEEEEEEEECCCEEEEEEEEECCCCCEEEEHHHHHHHHHHC
IENKNLKLEKGNYYKEFIKDAHLIIIAVNESSLVYKISKDCEKEYKLYLNAANYKEGMVA
CCCCCEEEECCCHHHHHHCCCEEEEEEECCCCEEEEHHHHHHHHHEEEEEECCCCCCEEE
IPYSRCYENLGFSISSKLGSPRITRAIGEEVSNIIKENDIYSIKVAKIREKAKKEELKDN
CCHHHHHHHCCCEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
IIEIISSKEFKNAILEKREYEYLKNLLGEELANSLTLGLK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCRNNREDIFNLVPINIISSKFHVKVIGGGKAATIKVKGLLEKGCYVHILSKEFSKEILD
CCCCCCCHHHHEECCEEECCEEEEEEEECCCEEEEEEEEECCCCCEEEEHHHHHHHHHHC
IENKNLKLEKGNYYKEFIKDAHLIIIAVNESSLVYKISKDCEKEYKLYLNAANYKEGMVA
CCCCCEEEECCCHHHHHHCCCEEEEEEECCCCEEEEHHHHHHHHHEEEEEECCCCCCEEE
IPYSRCYENLGFSISSKLGSPRITRAIGEEVSNIIKENDIYSIKVAKIREKAKKEELKDN
CCHHHHHHHCCCEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
IIEIISSKEFKNAILEKREYEYLKNLLGEELANSLTLGLK
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA