Click here to switch to the map view.

The map label for this gene is hemA [H]

Identifier: 18310419

GI number: 18310419

Start: 1694559

End: 1695761

Strand: Reverse

Name: hemA [H]

Synonym: CPE1437

Alternate gene names: 18310419

Gene position: 1695761-1694559 (Counterclockwise)

Preceding gene: 18310420

Following gene: 18310418

Centisome position: 55.94

GC content: 27.85

Gene sequence:

>1203_bases
ATGATAGGAGTTATAGGGGTTAAAAGGAATGTAGATATAGCAATAAGAGAAAAATTAGCCTTATATCCTAAAAAACATAA
GAAATACGTAGGAGAATTATTAAATTCATTTAAAGAAGTTGTAATATTAAATACTTGTAATAGAACAGAGATTTATTTTA
ATTGCACTGAAGAGATTTCAGAGGATGAAATTTTTGATAAAATTTTTAATGTGTTCAATTGGAATGATGATTTGAAAAAA
TATATGTTTTTATCAAAGGAAAAGAGAGCAGTAACCCATCTTATGGAGGTTATTTGTGGCTTTCATTCAAGAATTTTAGG
TGAAGATCAAATTCTAGGACAAATTAAAGATGCTTATAAAACAGCTATTTCAGATAATAGTATTTCATCAGAATTACAAA
AGATGTTTGAAATAGCTATTGCTTGTGGTAAAAAGTTTAAAACAGAGTGTAAAATGTTTGAAGTTCCAGTTTCATCAGTA
TCAATATCAATAAATAGTGCCCTATTAAAAGGATGCAGAAAATTTATGGTATTAGGATATGGAGAAATTGGGAAGTTGGC
AATTAAGCACCTTTTAAGTCATAAAGTAGAGTGTATTTATTTAATAGTAAGGGATAAGAGTAAGGCAAGTGATTTAGAGG
GTGAAATTGTAGAAGTTTTAGATTTTAATGAAAAAAATCAAGTTATAAATGAGGTTGATTGTATAGTTTCTTGTACAGCA
GCCCCTCATACAGTAGTGAGAAATGAAGATATAAAAACTGAAGGTGACATAATACATATATATGATTTAGCTGTTCCAAG
AGATGTCGATAAGGAATTATCAGAAAAAGAGAGAGTAATCCTTAAGGATATAGATGAAATAAGTAAGATTGATGATAAGA
ATAAAAAAATAAGAAAAGAAAGAATGGAAGAGTATAAGCATATAGTTGAAGAGAGCATAGAGGAATTTTTAAACTGGCTT
AAAATAAGAGAAGTTTCAAGTAAAATAAGAAACATAAAAATAAGAGAAAATGAAATTTGTAGTGAAAGAATAAAGACTTT
TTCTAATAAGGGAAATGGAGAAAATGCTAAATTAGCAGAAAGAATGATAAAAAGTACAGCTGATGCTTATGTTAATAGGG
CAATAGAACTTTTAAAAAGTGAAGCCTTAAAGGGAAGTGATAGTTCTTGTGCAGAAATAATAGAGAAGATATTTTTAACT
TAG

Upstream 100 bases:

>100_bases
TACAATTATTTCATTGGGCATATATAATTTTTATGATATTATAAAATAGAGTGTTTTAATAAAATTTTAACATATGATAT
AAAAACTTAGGAGGCAGTTC

Downstream 100 bases:

>100_bases
TACCAATAAACATTATAAGTAGTAAATTTCATGTTAAGGTCATAGGTGGAGGAAAAGCAGCCACCATAAAGGTTAAAGGA
TTATTAGAAAAAGGTTGTTA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEISEDEIFDKIFNVFNWNDDLKK
YMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYKTAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSV
SISINSALLKGCRKFMVLGYGEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTA
APHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKERMEEYKHIVEESIEEFLNWL
KIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAERMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT

Sequences:

>Translated_400_residues
MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEISEDEIFDKIFNVFNWNDDLKK
YMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYKTAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSV
SISINSALLKGCRKFMVLGYGEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTA
APHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKERMEEYKHIVEESIEEFLNWL
KIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAERMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT
>Mature_400_residues
MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEISEDEIFDKIFNVFNWNDDLKK
YMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYKTAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSV
SISINSALLKGCRKFMVLGYGEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTA
APHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKERMEEYKHIVEESIEEFLNWL
KIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAERMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=364, Percent_Identity=27.4725274725275, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 45891; Mature: 45891

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEIS
CEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECHHHCC
EDEIFDKIFNVFNWNDDLKKYMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSVSISINSALLKGCRKFMVLGY
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHEECCHHHHEEHHHHHHHHHHHHHHHHCC
GEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTA
CHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
APHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKE
CCCHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RMEEYKHIVEESIEEFLNWLKIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIGVIGVKRNVDIAIREKLALYPKKHKKYVGELLNSFKEVVILNTCNRTEIYFNCTEEIS
CEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECHHHCC
EDEIFDKIFNVFNWNDDLKKYMFLSKEKRAVTHLMEVICGFHSRILGEDQILGQIKDAYK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TAISDNSISSELQKMFEIAIACGKKFKTECKMFEVPVSSVSISINSALLKGCRKFMVLGY
HHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHEECCHHHHEEHHHHHHHHHHHHHHHHCC
GEIGKLAIKHLLSHKVECIYLIVRDKSKASDLEGEIVEVLDFNEKNQVINEVDCIVSCTA
CHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
APHTVVRNEDIKTEGDIIHIYDLAVPRDVDKELSEKERVILKDIDEISKIDDKNKKIRKE
CCCHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RMEEYKHIVEESIEEFLNWLKIREVSSKIRNIKIRENEICSERIKTFSNKGNGENAKLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
RMIKSTADAYVNRAIELLKSEALKGSDSSCAEIIEKIFLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10585141 [H]