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The map label for this gene is yhdH [H]

Identifier: 18310353

GI number: 18310353

Start: 1621905

End: 1623218

Strand: Direct

Name: yhdH [H]

Synonym: CPE1371

Alternate gene names: 18310353

Gene position: 1621905-1623218 (Clockwise)

Preceding gene: 18310352

Following gene: 18310354

Centisome position: 53.5

GC content: 29.68

Gene sequence:

>1314_bases
ATGAAAGAACGAGAAAATTTTACTGGAAAGTTTGGATTTGTAATATCCTGTGTTGGTGCCGCTTTAGGCCTTGGTAACAT
ATGGTTATTCTCCTACAGACTTGGTCAATATGGAGGTGCTGCTTTCTTAATACCATACTTTTTATTTGTTTTTATACTTG
GAACTACAGGTCTTATAACTGAATTTTCCTTTGGTAGAAAGTTTAAAGCAGGTTCATATACTGGTATAGTTGAATCTTTT
AAAAGTAAATCATTAAAGGGAGGAAAATTCTTTGGTATGCTCCCTCCTATAGGATTAACAGGAGTTTTTATATTTTACTC
TATAGTAATAGGTTGGATTCTTAAATACTTTTTCTTAAGTTTAACTGGATCTATTAATACTATTGATACTACTACTTACT
TTAGTAATTTTGCTGGCACACCTAATACAATCTTTTGGTTTGCCCTAGCAATAATATTAACTTTAATAATAGTTTCTTTA
GGAATAGACCGTGGTATAGAAAAATTAAACAAAATAGTTATTCCACTACTTCTTTTAATTTTTTTAATTTTAATCATAAG
ATCTTTAACTTTACCTGGCTCTTTTGAAGGTGTCAAATATCTATTAGTTCCAAGATGGGAAAACTTATTTAAAATAGATA
CTTGGATAATGGCTCTTGGCCAAGCATTTTTCACAGTCTCCCTTAATGGATGCGGTATGGTTGTTTATGGTAGTTATATA
AATGATAAATTTGATATTCCATCATCTGCAATACAAACTGCCATATTTGATACTTTAGCTGCCCTTTTAGCATCTTTTAT
GATTATGCCAGCAGTTTTTGCTTACGGATTAAATCCTTCATCTGGGCCATCTTTATTGTTTATAACTTTACCAAAAATAT
TTCAAGGTATGAATTTTGGTGCCTTACTAAGTACATTATTTTTTCTTAGTGTAATATTTGCTGCTATTTCATCCTCTGTA
AACATGTTAGAGGGTCCTGTTGAAGCTTTCATGACCCATTTTAAATCAAATAGAATAAAAACTTCAATTGTAATATCAGT
TCTTTGTTTTTTATGTGGAATACCTTTATCATTAAATATGGGAATCTTTGATAACTTTTCAAATCTTATTACAATAATAA
TTTCTCCCATTTGTGCTTTATTGGTAGCTGTTGTATTCTACTATATTATTGGTGGCGAAAATGTATTAATAGAAGTAAAT
AAGGGAGCTCATAAAAAACTTGGAAAATGGTTTATTCCTTTAGGGAAATACATTTTTATCTTAGTTACTATACTAGTAAT
AATTCTTGGAATAATATATGGTGGTATAGGTTAA

Upstream 100 bases:

>100_bases
TATATGGCCTTAATAAAGAGTTTTAATACCCTATAGGTCGTATAGTTTAACTATATGACCTATTTTTTATATTTATATAA
AAATCTAGGAGGTATTTTAA

Downstream 100 bases:

>100_bases
ATTTAAACATTGTAAGTTTTGATAAAAATTTTTATTTAATAATTAATATTACTTGACCTAATTGCAATTTGCATATAAAA
TATACTTAGAATTATTTCAT

Product: sodium- and chloride- dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKERENFTGKFGFVISCVGAALGLGNIWLFSYRLGQYGGAAFLIPYFLFVFILGTTGLITEFSFGRKFKAGSYTGIVESF
KSKSLKGGKFFGMLPPIGLTGVFIFYSIVIGWILKYFFLSLTGSINTIDTTTYFSNFAGTPNTIFWFALAIILTLIIVSL
GIDRGIEKLNKIVIPLLLLIFLILIIRSLTLPGSFEGVKYLLVPRWENLFKIDTWIMALGQAFFTVSLNGCGMVVYGSYI
NDKFDIPSSAIQTAIFDTLAALLASFMIMPAVFAYGLNPSSGPSLLFITLPKIFQGMNFGALLSTLFFLSVIFAAISSSV
NMLEGPVEAFMTHFKSNRIKTSIVISVLCFLCGIPLSLNMGIFDNFSNLITIIISPICALLVAVVFYYIIGGENVLIEVN
KGAHKKLGKWFIPLGKYIFILVTILVIILGIIYGGIG

Sequences:

>Translated_437_residues
MKERENFTGKFGFVISCVGAALGLGNIWLFSYRLGQYGGAAFLIPYFLFVFILGTTGLITEFSFGRKFKAGSYTGIVESF
KSKSLKGGKFFGMLPPIGLTGVFIFYSIVIGWILKYFFLSLTGSINTIDTTTYFSNFAGTPNTIFWFALAIILTLIIVSL
GIDRGIEKLNKIVIPLLLLIFLILIIRSLTLPGSFEGVKYLLVPRWENLFKIDTWIMALGQAFFTVSLNGCGMVVYGSYI
NDKFDIPSSAIQTAIFDTLAALLASFMIMPAVFAYGLNPSSGPSLLFITLPKIFQGMNFGALLSTLFFLSVIFAAISSSV
NMLEGPVEAFMTHFKSNRIKTSIVISVLCFLCGIPLSLNMGIFDNFSNLITIIISPICALLVAVVFYYIIGGENVLIEVN
KGAHKKLGKWFIPLGKYIFILVTILVIILGIIYGGIG
>Mature_437_residues
MKERENFTGKFGFVISCVGAALGLGNIWLFSYRLGQYGGAAFLIPYFLFVFILGTTGLITEFSFGRKFKAGSYTGIVESF
KSKSLKGGKFFGMLPPIGLTGVFIFYSIVIGWILKYFFLSLTGSINTIDTTTYFSNFAGTPNTIFWFALAIILTLIIVSL
GIDRGIEKLNKIVIPLLLLIFLILIIRSLTLPGSFEGVKYLLVPRWENLFKIDTWIMALGQAFFTVSLNGCGMVVYGSYI
NDKFDIPSSAIQTAIFDTLAALLASFMIMPAVFAYGLNPSSGPSLLFITLPKIFQGMNFGALLSTLFFLSVIFAAISSSV
NMLEGPVEAFMTHFKSNRIKTSIVISVLCFLCGIPLSLNMGIFDNFSNLITIIISPICALLVAVVFYYIIGGENVLIEVN
KGAHKKLGKWFIPLGKYIFILVTILVIILGIIYGGIG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=402, Percent_Identity=27.1144278606965, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI134304856, Length=449, Percent_Identity=27.1714922048998, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4507043, Length=408, Percent_Identity=25.4901960784314, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI171184408, Length=428, Percent_Identity=28.7383177570093, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184406, Length=428, Percent_Identity=28.7383177570093, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI171184404, Length=428, Percent_Identity=28.7383177570093, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194018524, Length=306, Percent_Identity=27.4509803921569, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI21361581, Length=440, Percent_Identity=26.3636363636364, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI67782317, Length=473, Percent_Identity=24.1014799154334, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI67782313, Length=473, Percent_Identity=24.1014799154334, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI67782315, Length=473, Percent_Identity=24.1014799154334, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI51468073, Length=268, Percent_Identity=28.7313432835821, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI7657587, Length=388, Percent_Identity=27.5773195876289, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI33354281, Length=309, Percent_Identity=24.2718446601942, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI197276623, Length=490, Percent_Identity=24.4897959183673, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI54607094, Length=490, Percent_Identity=24.4897959183673, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI4507041, Length=476, Percent_Identity=22.8991596638655, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI92859670, Length=449, Percent_Identity=25.3897550111359, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI58219014, Length=318, Percent_Identity=22.9559748427673, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI5032097, Length=501, Percent_Identity=23.3532934131737, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI218563756, Length=496, Percent_Identity=23.3870967741935, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI12408638, Length=274, Percent_Identity=22.992700729927, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI300360519, Length=257, Percent_Identity=26.8482490272374, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=411, Percent_Identity=24.5742092457421, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17554804, Length=472, Percent_Identity=25.2118644067797, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI133952791, Length=437, Percent_Identity=25.629290617849, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17569475, Length=516, Percent_Identity=24.031007751938, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71998244, Length=405, Percent_Identity=25.1851851851852, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25146584, Length=427, Percent_Identity=23.6533957845433, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71995588, Length=451, Percent_Identity=23.059866962306, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24762620, Length=406, Percent_Identity=26.6009852216749, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24661428, Length=411, Percent_Identity=26.5206812652068, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136952, Length=496, Percent_Identity=22.3790322580645, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19921936, Length=378, Percent_Identity=26.7195767195767, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24639514, Length=412, Percent_Identity=25.2427184466019, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221329674, Length=412, Percent_Identity=25.2427184466019, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582567, Length=456, Percent_Identity=25.6578947368421, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45551183, Length=420, Percent_Identity=23.3333333333333, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550877, Length=422, Percent_Identity=23.4597156398104, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281364394, Length=496, Percent_Identity=21.9758064516129, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574704, Length=496, Percent_Identity=21.9758064516129, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136950, Length=496, Percent_Identity=21.9758064516129, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574702, Length=496, Percent_Identity=21.9758064516129, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639516, Length=432, Percent_Identity=24.7685185185185, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652942, Length=407, Percent_Identity=23.3415233415233, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45551088, Length=407, Percent_Identity=23.3415233415233, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655079, Length=524, Percent_Identity=21.9465648854962, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281363702, Length=368, Percent_Identity=24.4565217391304, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281364136, Length=440, Percent_Identity=23.6363636363636, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24582569, Length=417, Percent_Identity=24.4604316546763, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24654186, Length=206, Percent_Identity=27.1844660194175, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921352, Length=207, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24584353, Length=207, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281365034, Length=207, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47946; Mature: 47946

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERENFTGKFGFVISCVGAALGLGNIWLFSYRLGQYGGAAFLIPYFLFVFILGTTGLIT
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHH
EFSFGRKFKAGSYTGIVESFKSKSLKGGKFFGMLPPIGLTGVFIFYSIVIGWILKYFFLS
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTGSINTIDTTTYFSNFAGTPNTIFWFALAIILTLIIVSLGIDRGIEKLNKIVIPLLLLI
HCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLILIIRSLTLPGSFEGVKYLLVPRWENLFKIDTWIMALGQAFFTVSLNGCGMVVYGSYI
HHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCC
NDKFDIPSSAIQTAIFDTLAALLASFMIMPAVFAYGLNPSSGPSLLFITLPKIFQGMNFG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHH
ALLSTLFFLSVIFAAISSSVNMLEGPVEAFMTHFKSNRIKTSIVISVLCFLCGIPLSLNM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEECC
GIFDNFSNLITIIISPICALLVAVVFYYIIGGENVLIEVNKGAHKKLGKWFIPLGKYIFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LVTILVIILGIIYGGIG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKERENFTGKFGFVISCVGAALGLGNIWLFSYRLGQYGGAAFLIPYFLFVFILGTTGLIT
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHH
EFSFGRKFKAGSYTGIVESFKSKSLKGGKFFGMLPPIGLTGVFIFYSIVIGWILKYFFLS
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTGSINTIDTTTYFSNFAGTPNTIFWFALAIILTLIIVSLGIDRGIEKLNKIVIPLLLLI
HCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLILIIRSLTLPGSFEGVKYLLVPRWENLFKIDTWIMALGQAFFTVSLNGCGMVVYGSYI
HHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCC
NDKFDIPSSAIQTAIFDTLAALLASFMIMPAVFAYGLNPSSGPSLLFITLPKIFQGMNFG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCCHH
ALLSTLFFLSVIFAAISSSVNMLEGPVEAFMTHFKSNRIKTSIVISVLCFLCGIPLSLNM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEECC
GIFDNFSNLITIIISPICALLVAVVFYYIIGGENVLIEVNKGAHKKLGKWFIPLGKYIFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
LVTILVIILGIIYGGIG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]