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The map label for this gene is thrS [H]

Identifier: 18310329

GI number: 18310329

Start: 1591305

End: 1592969

Strand: Reverse

Name: thrS [H]

Synonym: CPE1347

Alternate gene names: 18310329

Gene position: 1592969-1591305 (Counterclockwise)

Preceding gene: 18310333

Following gene: 18310326

Centisome position: 52.55

GC content: 28.35

Gene sequence:

>1665_bases
ATGGTGTTTATGAAAAGCTTTAGGGTTAGTGTAAATGGGGAAAGTTTACTCTTTAATGAGGGAGAAAAATATTCAGTAAT
TTTAAAAAAGGACTATATAAATGAAAAAATACCTATTACTTTAGTTAAACAGAGGAATAAGTATTATGAGTTTACTGATT
TAATAAATAATGATGGGGATATAGAACTTATAAATATAAGTGATCCACATGGAAAAATAGCTTATAGTAGAACTTTACAG
TTTGTATTTATAAAAGCAACTTTAGACTTATTTAAGGATGCTAGAATAAATATAGAGCATTCTATAAGCAAGGGAACTTT
TGGGGAAATTCACAAAGAAAAGGCCTTAGATGAAGAGGATATACTAAAAATAAAGAAAAAAATGCAAGAGATAATAAATA
AAAATATTATAATAGAAAAAATAAAGATGCCTAAGAAAGAGGCTATTGATATATTTAAATCTTATAAGATGCAGGATAAA
GTTGATTTATTACATTGGGTTCAAGAAGAGTATGTAAACTTATATAAATTAGAAGATAGGTATGATTATTTTTATGGAGA
TATGGCATACTCTACAGGAGTTTTAAAATATTTTGATTTATTATATTATAATCCAGGTTTTATACTTATGGTACCAAGCC
ATAAGGAGCCAACAGTTGTACCTGTCTTTAAGGAACAAAAAAAGTTATTTAATGTATTTAGAGAGAATGAAACATGGTTA
AATATATTAGGAACTCCAGATGTAGGTTCTTTAGATTATAAATTAGAGGGAGAAGAATCCTCAGACATAATAAGGGTTTC
TGAGGCTTTACATGAGAAGAAAATAGCACAAATTGCAGATATGATAAGTGATAGAAAAGAGGTTAAAATTGTTTTAGTAG
CAGGGCCTTCCTCTTCAGGTAAAACAACATTTTCAAAAAGACTTTCTATACAGCTTAGAGTTAATGGCTATATACCAATA
GCTATATCCTTAGATGATTATTTTATAAATAGAATTCATACTCCTTTAGATGAAGAGGGAAAACCTGATTTTGAATCTAT
AAATGCTTTAGATTTAGAATTATTTAATAAGAATCTTTATGATATTTTAGAAGGGGAAGAAGTAGAAATACCTTCTTATA
ATTTTAAAATAGGAGAAAGAGAATGGCTAGGCAACAAGATTAAACTTCCTGATAATGGAGTGCTTGTTATAGAGGGAATA
CATGGACTAAATCCAAAACTGACAGAAAAAATTCCTTCAAAGAATAAGTTTAAGGTTTATATTTCTGCTTTAACACAATT
AAATTTAGATAATCACAATAGAATTCCAACTACAGATGTCAGAAAAATAAGACGTATAGTTAGGGATTCTTTATCAAGAG
GATATGGAGCAGAGCAAACTTTAGAAATGTGGAGTTCTATAAAAAGAGGAGAGGAAAAGAACATATTTGTTTATCAGGAA
GAAGCAGATGTTATGTTTAACTCCACTTTAGTTTATGAATTAGCAGCTTTAAAGGAATATGCCTTAAGAGAGTTAGAAAA
AGTAGATAAAAACAGCAGTGTTTACTATGAAGCTAAAAGAATAATAAATACATTAAAGTTTTTTGTGGAAGTTAAGCCAG
AGAGAGTACCTGAAAATTCGATTTTAAGAGAATTTATAGGTGGAAGTTGCTTCTATAAGTATTAA

Upstream 100 bases:

>100_bases
AATAGGGTAACAAATTTAAAGGGGATTTATACAAAAATAGATAATTTTTTTGAAGTTTTAAGTGTATAATAACAATAAGG
TGGCTTATAAGTAGAGAGGA

Downstream 100 bases:

>100_bases
TTAAATTAAAATTAAAAATATAGTAAGGAATTTATTATCTTTAATACTTAAAATATATTAGAAATTAAGTAGGGATTAAT
ACAATTTATAAAGATTAGTT

Product: uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MVFMKSFRVSVNGESLLFNEGEKYSVILKKDYINEKIPITLVKQRNKYYEFTDLINNDGDIELINISDPHGKIAYSRTLQ
FVFIKATLDLFKDARINIEHSISKGTFGEIHKEKALDEEDILKIKKKMQEIINKNIIIEKIKMPKKEAIDIFKSYKMQDK
VDLLHWVQEEYVNLYKLEDRYDYFYGDMAYSTGVLKYFDLLYYNPGFILMVPSHKEPTVVPVFKEQKKLFNVFRENETWL
NILGTPDVGSLDYKLEGEESSDIIRVSEALHEKKIAQIADMISDRKEVKIVLVAGPSSSGKTTFSKRLSIQLRVNGYIPI
AISLDDYFINRIHTPLDEEGKPDFESINALDLELFNKNLYDILEGEEVEIPSYNFKIGEREWLGNKIKLPDNGVLVIEGI
HGLNPKLTEKIPSKNKFKVYISALTQLNLDNHNRIPTTDVRKIRRIVRDSLSRGYGAEQTLEMWSSIKRGEEKNIFVYQE
EADVMFNSTLVYELAALKEYALRELEKVDKNSSVYYEAKRIINTLKFFVEVKPERVPENSILREFIGGSCFYKY

Sequences:

>Translated_554_residues
MVFMKSFRVSVNGESLLFNEGEKYSVILKKDYINEKIPITLVKQRNKYYEFTDLINNDGDIELINISDPHGKIAYSRTLQ
FVFIKATLDLFKDARINIEHSISKGTFGEIHKEKALDEEDILKIKKKMQEIINKNIIIEKIKMPKKEAIDIFKSYKMQDK
VDLLHWVQEEYVNLYKLEDRYDYFYGDMAYSTGVLKYFDLLYYNPGFILMVPSHKEPTVVPVFKEQKKLFNVFRENETWL
NILGTPDVGSLDYKLEGEESSDIIRVSEALHEKKIAQIADMISDRKEVKIVLVAGPSSSGKTTFSKRLSIQLRVNGYIPI
AISLDDYFINRIHTPLDEEGKPDFESINALDLELFNKNLYDILEGEEVEIPSYNFKIGEREWLGNKIKLPDNGVLVIEGI
HGLNPKLTEKIPSKNKFKVYISALTQLNLDNHNRIPTTDVRKIRRIVRDSLSRGYGAEQTLEMWSSIKRGEEKNIFVYQE
EADVMFNSTLVYELAALKEYALRELEKVDKNSSVYYEAKRIINTLKFFVEVKPERVPENSILREFIGGSCFYKY
>Mature_554_residues
MVFMKSFRVSVNGESLLFNEGEKYSVILKKDYINEKIPITLVKQRNKYYEFTDLINNDGDIELINISDPHGKIAYSRTLQ
FVFIKATLDLFKDARINIEHSISKGTFGEIHKEKALDEEDILKIKKKMQEIINKNIIIEKIKMPKKEAIDIFKSYKMQDK
VDLLHWVQEEYVNLYKLEDRYDYFYGDMAYSTGVLKYFDLLYYNPGFILMVPSHKEPTVVPVFKEQKKLFNVFRENETWL
NILGTPDVGSLDYKLEGEESSDIIRVSEALHEKKIAQIADMISDRKEVKIVLVAGPSSSGKTTFSKRLSIQLRVNGYIPI
AISLDDYFINRIHTPLDEEGKPDFESINALDLELFNKNLYDILEGEEVEIPSYNFKIGEREWLGNKIKLPDNGVLVIEGI
HGLNPKLTEKIPSKNKFKVYISALTQLNLDNHNRIPTTDVRKIRRIVRDSLSRGYGAEQTLEMWSSIKRGEEKNIFVYQE
EADVMFNSTLVYELAALKEYALRELEKVDKNSSVYYEAKRIINTLKFFVEVKPERVPENSILREFIGGSCFYKY

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64486; Mature: 64486

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFMKSFRVSVNGESLLFNEGEKYSVILKKDYINEKIPITLVKQRNKYYEFTDLINNDGD
CEEEEEEEEEECCCEEEEECCCEEEEEEEECCCCCCCCEEEEECCCCEEEEHHHHCCCCC
IELINISDPHGKIAYSRTLQFVFIKATLDLFKDARINIEHSISKGTFGEIHKEKALDEED
EEEEEECCCCCCEEEEEEEEEEEEEEHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCHHH
ILKIKKKMQEIINKNIIIEKIKMPKKEAIDIFKSYKMQDKVDLLHWVQEEYVNLYKLEDR
HHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECC
YDYFYGDMAYSTGVLKYFDLLYYNPGFILMVPSHKEPTVVPVFKEQKKLFNVFRENETWL
CCEEECCHHHHHHHHHHHHHHEECCCEEEEECCCCCCCEEECHHHHHHHHHHHHCCCCEE
NILGTPDVGSLDYKLEGEESSDIIRVSEALHEKKIAQIADMISDRKEVKIVLVAGPSSSG
EEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
KTTFSKRLSIQLRVNGYIPIAISLDDYFINRIHTPLDEEGKPDFESINALDLELFNKNLY
CCEEEEEEEEEEEECCEEEEEEEECHHHHHHHCCCCCCCCCCCHHHCCEEEHHHHCCCHH
DILEGEEVEIPSYNFKIGEREWLGNKIKLPDNGVLVIEGIHGLNPKLTEKIPSKNKFKVY
HHHCCCEEECCCCCEEECCHHHCCCEEECCCCCEEEEECCCCCCCHHHHHCCCCCCEEEE
ISALTQLNLDNHNRIPTTDVRKIRRIVRDSLSRGYGAEQTLEMWSSIKRGEEKNIFVYQE
EEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEC
EADVMFNSTLVYELAALKEYALRELEKVDKNSSVYYEAKRIINTLKFFVEVKPERVPENS
CCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHH
ILREFIGGSCFYKY
HHHHHHCCCEEECC
>Mature Secondary Structure
MVFMKSFRVSVNGESLLFNEGEKYSVILKKDYINEKIPITLVKQRNKYYEFTDLINNDGD
CEEEEEEEEEECCCEEEEECCCEEEEEEEECCCCCCCCEEEEECCCCEEEEHHHHCCCCC
IELINISDPHGKIAYSRTLQFVFIKATLDLFKDARINIEHSISKGTFGEIHKEKALDEED
EEEEEECCCCCCEEEEEEEEEEEEEEHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCHHH
ILKIKKKMQEIINKNIIIEKIKMPKKEAIDIFKSYKMQDKVDLLHWVQEEYVNLYKLEDR
HHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECC
YDYFYGDMAYSTGVLKYFDLLYYNPGFILMVPSHKEPTVVPVFKEQKKLFNVFRENETWL
CCEEECCHHHHHHHHHHHHHHEECCCEEEEECCCCCCCEEECHHHHHHHHHHHHCCCCEE
NILGTPDVGSLDYKLEGEESSDIIRVSEALHEKKIAQIADMISDRKEVKIVLVAGPSSSG
EEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
KTTFSKRLSIQLRVNGYIPIAISLDDYFINRIHTPLDEEGKPDFESINALDLELFNKNLY
CCEEEEEEEEEEEECCEEEEEEEECHHHHHHHCCCCCCCCCCCHHHCCEEEHHHHCCCHH
DILEGEEVEIPSYNFKIGEREWLGNKIKLPDNGVLVIEGIHGLNPKLTEKIPSKNKFKVY
HHHCCCEEECCCCCEEECCHHHCCCEEECCCCCEEEEECCCCCCCHHHHHCCCCCCEEEE
ISALTQLNLDNHNRIPTTDVRKIRRIVRDSLSRGYGAEQTLEMWSSIKRGEEKNIFVYQE
EEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEC
EADVMFNSTLVYELAALKEYALRELEKVDKNSSVYYEAKRIINTLKFFVEVKPERVPENS
CCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEECCCCCCHHH
ILREFIGGSCFYKY
HHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA