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The map label for this gene is resE [H]

Identifier: 18310298

GI number: 18310298

Start: 1556909

End: 1559374

Strand: Reverse

Name: resE [H]

Synonym: CPE1316

Alternate gene names: 18310298

Gene position: 1559374-1556909 (Counterclockwise)

Preceding gene: 18310300

Following gene: 18310297

Centisome position: 51.44

GC content: 22.87

Gene sequence:

>2466_bases
ATGAATAAATTTTTGAAAAAAGAGGTATTTTTACTTATTTTAAATATTTATTTAATATATAATAGAAGTACTATGCTAAA
TAAGAATGGGGAAAATTTAGATATGTTAATTGGACTTTTTAACAATTTAGGTATTAAAGAGAAAACATTAAAAAGAATAG
CAATAGTCACAGTAATATTACTTAGTTTATTTTTTATAAAAGGGTTAAATTTAATTTGTGCCTTAAATAGAGATTTGTTT
AAGGATGTAAGTGTAGTTTATGCTGCTGAAGAAATTATAGTAATGACTCAAATAATTCTTTGTATTATGATATTATCTAT
ATGCTTTATATATTATAGAGGACTTAAACGAAAAGAGTTCTTTAGTATATCACTTGTTTATGTAAGTATTATTACTGAAA
TGATTTTTATAGTCTTAACAGGAAAAATAGTTGAAAATCAGGTTTATGACTTGAATTTATTTAGTTTGTTATTTAGAGGG
ATATTACTACTTTTAGCTGTTTTATGCCTTGAAAATTTTGATGCTTTTATAAGGAAATATAAAAAATTAACCTTAGTATT
TGTAATATTGGTAACGATTATATTACAAATATTAAATGTTAATTATAACATAGGAATATATACATATAATTTTATATATA
ATTTAACTTTAGTTTTAATAGTTTTAACATATATATCTTGTATAATATTTTGTTTAGTTAGAATTTTTCAATTTAGAGAA
ATAACTTATTTAGTAATAATGATAAGTGCTTCACTTATGTTATTAAAATTAGTTTATGGCCTTTCTTTAAGTATAACGAA
TAATAATCTTATAAAAATAAATATTGTATTTTTTAATTTTATATCATTTATGAGCTTTGTATTTGGTATGTTTTTTGATT
TACTTCAAGTTATAAAAAATAAAAATTTTATGCAAGAAGAATTAAGTGCATTTTTTAACCTAATAGAATTTGATTGTAAT
AGTGAAGTTGTAGTACTTAGTAACAATTTAAAAGTTCTTTATGCAAATGAAAAATGTAGAAGTAAGAGAATATCACCTAA
AAATAGAGAAAATAAAACTTATATTGATTTAGAAAAACAAATTAAAGGATTTTTATATGATAAAAATATAATTTGTATAG
AAAGTGTGCTTAGAAATTCTAAGGAATGGAAAGGTATAATAAAGTTAAATGAAGAGGATGAAGTTGTAAAAGTAAATCTT
CAGAGAATAAAAAAAGAAAAAAATCTTTATTATGTACTTAGAATTAATGATATAACAGAAGAATACAAAATGGAGAAAAA
TTTAAAATTAGAGGAGCAAAGGCTTAGAGGAGTTACTGAAAATATAAAAGATTTAATATTTACAATTGATGTTGAAGGAA
AAATAAGCTATGTAAACAAAGCAGTAATAGATGTTTTAGGATATAGCGAAGAAGAATTAATAGGAAAAAATTATTATGAT
CTATTATTGGTTGAATCTAATTTAAATATAATAGACAGCAAATATTTTAATGAAGATAAGATTTTAACAATAGATAAGGT
AAGATCTAAAAAAGGGTTGGTTCAATTAGAATCTATTTCTAGTAGAATTAAGGATAATAAAAATAATACCTTAGGATGGG
TAAGAGTTGCTAGAAATATAGAGGATGTAAGAGAAATAGAAATATTAAAGAATAAATTTGAAGAAATAAAGCAATATGAC
AAGGTTAGAAGTGAGTTTTTTGCAAATTTATCTCATGAGCTTAGAACTCCTATTAACATAATATATTCATGCATACAGCT
TTTAAACACTAGTAAAAAGAATAAGGCAAACTTTGCTAATTTATATGATAAGTATGAAAAAACTTTAAAACAAAATTGTT
TTAGAATGTTAAGGCTTGTAAATAATCTTATAGATATAACAAAAATAGACTCTGGTTTTATTAAGATGGACTTTATTAAT
TATGACATAATAAAGCTTACAGAAGATATAACTATGTCTGTAATTCCTTATGTAGAATCTAAGAATATAGATATAATCTT
TGATACTGATTATGAGGAATTAGAGATAAGGTGTGACCCAGATAAAATTGAGAGAATAATTTTAAATTTATTATCTAATG
CCATAAAATTTACAGAGCCAGGTGGAAAAATAGAAGTTAGTATTTTTGCAGATGAAGCTTGGGTAGATATAAGGGTTAAG
GATACAGGTATAGGAATTCCATCACACATGAAAGAATTTATTTTTGAAAGATTTATACAAAATGATAAATCCTTAAATAG
AAATAAAGAAGGAAGTGGAATAGGATTATCCTTAGTTAAATCTTTAGTGGAATTACATGAAGGAAAAGTTTTCTTAAGAG
AAAGTAATGAATCAGGTAGTGAATTTTCAATATTACTACCTAATGTGAAATTGGAGAATGATGTTTGCGAAAATGGAAGC
TTAGATTATAAAACAGAGGTTGAAAAAATATCAATAGAGTTTGCTGATATTTATGAAATATATTAG

Upstream 100 bases:

>100_bases
TTTAATCCTCCTATTAAATTGTTGAAATTTTTATAATAACATTTTAGATGTTAAAAATAAATAGGTCAATATTAATAATA
TATAGTAATTTTATGAAGAA

Downstream 100 bases:

>100_bases
GAGATTTAATAAGTTTAAATGATTTCATAAACTTTCTATTTTAAAAAGATAATGATATAATATTAAGGGCTTGTTTAAAA
AAGACAAGTCCTTAATTATT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MNKFLKKEVFLLILNIYLIYNRSTMLNKNGENLDMLIGLFNNLGIKEKTLKRIAIVTVILLSLFFIKGLNLICALNRDLF
KDVSVVYAAEEIIVMTQIILCIMILSICFIYYRGLKRKEFFSISLVYVSIITEMIFIVLTGKIVENQVYDLNLFSLLFRG
ILLLLAVLCLENFDAFIRKYKKLTLVFVILVTIILQILNVNYNIGIYTYNFIYNLTLVLIVLTYISCIIFCLVRIFQFRE
ITYLVIMISASLMLLKLVYGLSLSITNNNLIKINIVFFNFISFMSFVFGMFFDLLQVIKNKNFMQEELSAFFNLIEFDCN
SEVVVLSNNLKVLYANEKCRSKRISPKNRENKTYIDLEKQIKGFLYDKNIICIESVLRNSKEWKGIIKLNEEDEVVKVNL
QRIKKEKNLYYVLRINDITEEYKMEKNLKLEEQRLRGVTENIKDLIFTIDVEGKISYVNKAVIDVLGYSEEELIGKNYYD
LLLVESNLNIIDSKYFNEDKILTIDKVRSKKGLVQLESISSRIKDNKNNTLGWVRVARNIEDVREIEILKNKFEEIKQYD
KVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANFANLYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFIN
YDIIKLTEDITMSVIPYVESKNIDIIFDTDYEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSIFADEAWVDIRVK
DTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGSEFSILLPNVKLENDVCENGS
LDYKTEVEKISIEFADIYEIY

Sequences:

>Translated_821_residues
MNKFLKKEVFLLILNIYLIYNRSTMLNKNGENLDMLIGLFNNLGIKEKTLKRIAIVTVILLSLFFIKGLNLICALNRDLF
KDVSVVYAAEEIIVMTQIILCIMILSICFIYYRGLKRKEFFSISLVYVSIITEMIFIVLTGKIVENQVYDLNLFSLLFRG
ILLLLAVLCLENFDAFIRKYKKLTLVFVILVTIILQILNVNYNIGIYTYNFIYNLTLVLIVLTYISCIIFCLVRIFQFRE
ITYLVIMISASLMLLKLVYGLSLSITNNNLIKINIVFFNFISFMSFVFGMFFDLLQVIKNKNFMQEELSAFFNLIEFDCN
SEVVVLSNNLKVLYANEKCRSKRISPKNRENKTYIDLEKQIKGFLYDKNIICIESVLRNSKEWKGIIKLNEEDEVVKVNL
QRIKKEKNLYYVLRINDITEEYKMEKNLKLEEQRLRGVTENIKDLIFTIDVEGKISYVNKAVIDVLGYSEEELIGKNYYD
LLLVESNLNIIDSKYFNEDKILTIDKVRSKKGLVQLESISSRIKDNKNNTLGWVRVARNIEDVREIEILKNKFEEIKQYD
KVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANFANLYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFIN
YDIIKLTEDITMSVIPYVESKNIDIIFDTDYEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSIFADEAWVDIRVK
DTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGSEFSILLPNVKLENDVCENGS
LDYKTEVEKISIEFADIYEIY
>Mature_821_residues
MNKFLKKEVFLLILNIYLIYNRSTMLNKNGENLDMLIGLFNNLGIKEKTLKRIAIVTVILLSLFFIKGLNLICALNRDLF
KDVSVVYAAEEIIVMTQIILCIMILSICFIYYRGLKRKEFFSISLVYVSIITEMIFIVLTGKIVENQVYDLNLFSLLFRG
ILLLLAVLCLENFDAFIRKYKKLTLVFVILVTIILQILNVNYNIGIYTYNFIYNLTLVLIVLTYISCIIFCLVRIFQFRE
ITYLVIMISASLMLLKLVYGLSLSITNNNLIKINIVFFNFISFMSFVFGMFFDLLQVIKNKNFMQEELSAFFNLIEFDCN
SEVVVLSNNLKVLYANEKCRSKRISPKNRENKTYIDLEKQIKGFLYDKNIICIESVLRNSKEWKGIIKLNEEDEVVKVNL
QRIKKEKNLYYVLRINDITEEYKMEKNLKLEEQRLRGVTENIKDLIFTIDVEGKISYVNKAVIDVLGYSEEELIGKNYYD
LLLVESNLNIIDSKYFNEDKILTIDKVRSKKGLVQLESISSRIKDNKNNTLGWVRVARNIEDVREIEILKNKFEEIKQYD
KVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANFANLYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFIN
YDIIKLTEDITMSVIPYVESKNIDIIFDTDYEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSIFADEAWVDIRVK
DTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGSEFSILLPNVKLENDVCENGS
LDYKTEVEKISIEFADIYEIY

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=29.7520661157025, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=26.4, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786600, Length=361, Percent_Identity=25.4847645429363, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=305, Percent_Identity=29.1803278688525, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=26.0683760683761, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI48994928, Length=386, Percent_Identity=24.3523316062176, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1788393, Length=266, Percent_Identity=24.4360902255639, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1786783, Length=288, Percent_Identity=29.5138888888889, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=20.5128205128205, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=369, Percent_Identity=24.1192411924119, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=25.8333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=29.0178571428571, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788279, Length=287, Percent_Identity=26.4808362369338, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790551, Length=219, Percent_Identity=23.2876712328767, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=22.4576271186441, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 95818; Mature: 95818

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFLKKEVFLLILNIYLIYNRSTMLNKNGENLDMLIGLFNNLGIKEKTLKRIAIVTVIL
CCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LSLFFIKGLNLICALNRDLFKDVSVVYAAEEIIVMTQIILCIMILSICFIYYRGLKRKEF
HHHHHHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FSISLVYVSIITEMIFIVLTGKIVENQVYDLNLFSLLFRGILLLLAVLCLENFDAFIRKY
HHHHHHHHHHHHHHHHHHHHCHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKLTLVFVILVTIILQILNVNYNIGIYTYNFIYNLTLVLIVLTYISCIIFCLVRIFQFRE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITYLVIMISASLMLLKLVYGLSLSITNNNLIKINIVFFNFISFMSFVFGMFFDLLQVIKN
HHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
KNFMQEELSAFFNLIEFDCNSEVVVLSNNLKVLYANEKCRSKRISPKNRENKTYIDLEKQ
CCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCHHHHCCCCCCCCCCCEEEEHHHH
IKGFLYDKNIICIESVLRNSKEWKGIIKLNEEDEVVKVNLQRIKKEKNLYYVLRINDITE
HHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHCCCEEEEEEECCCHH
EYKMEKNLKLEEQRLRGVTENIKDLIFTIDVEGKISYVNKAVIDVLGYSEEELIGKNYYD
HHHHHCCCCHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCEE
LLLVESNLNIIDSKYFNEDKILTIDKVRSKKGLVQLESISSRIKDNKNNTLGWVRVARNI
EEEEECCCCEEECCCCCCCCEEEHHHHHCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHCH
EDVREIEILKNKFEEIKQYDKVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHH
LYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFINYDIIKLTEDITMSVIPYVES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCEEEECCEEC
KNIDIIFDTDYEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSIFADEAWVDIRVK
CCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCEEEEEEEE
DTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCC
EFSILLPNVKLENDVCENGSLDYKTEVEKISIEFADIYEIY
EEEEEECCCEECCCCCCCCCCCCEECHHHEEEEEHHHEECC
>Mature Secondary Structure
MNKFLKKEVFLLILNIYLIYNRSTMLNKNGENLDMLIGLFNNLGIKEKTLKRIAIVTVIL
CCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LSLFFIKGLNLICALNRDLFKDVSVVYAAEEIIVMTQIILCIMILSICFIYYRGLKRKEF
HHHHHHCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
FSISLVYVSIITEMIFIVLTGKIVENQVYDLNLFSLLFRGILLLLAVLCLENFDAFIRKY
HHHHHHHHHHHHHHHHHHHHCHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKLTLVFVILVTIILQILNVNYNIGIYTYNFIYNLTLVLIVLTYISCIIFCLVRIFQFRE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITYLVIMISASLMLLKLVYGLSLSITNNNLIKINIVFFNFISFMSFVFGMFFDLLQVIKN
HHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
KNFMQEELSAFFNLIEFDCNSEVVVLSNNLKVLYANEKCRSKRISPKNRENKTYIDLEKQ
CCHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECCHHHHCCCCCCCCCCCEEEEHHHH
IKGFLYDKNIICIESVLRNSKEWKGIIKLNEEDEVVKVNLQRIKKEKNLYYVLRINDITE
HHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHCCCEEEEEEECCCHH
EYKMEKNLKLEEQRLRGVTENIKDLIFTIDVEGKISYVNKAVIDVLGYSEEELIGKNYYD
HHHHHCCCCHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHCCCHHHHCCCCCEE
LLLVESNLNIIDSKYFNEDKILTIDKVRSKKGLVQLESISSRIKDNKNNTLGWVRVARNI
EEEEECCCCEEECCCCCCCCEEEHHHHHCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHCH
EDVREIEILKNKFEEIKQYDKVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHH
LYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFINYDIIKLTEDITMSVIPYVES
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCEEEECCEEC
KNIDIIFDTDYEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSIFADEAWVDIRVK
CCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCEEEEEEEE
DTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGS
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCC
EFSILLPNVKLENDVCENGSLDYKTEVEKISIEFADIYEIY
EEEEEECCCEECCCCCCCCCCCCEECHHHEEEEEHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]