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The map label for this gene is lacZ [H]

Identifier: 18310248

GI number: 18310248

Start: 1482112

End: 1486179

Strand: Reverse

Name: lacZ [H]

Synonym: CPE1266

Alternate gene names: 18310248

Gene position: 1486179-1482112 (Counterclockwise)

Preceding gene: 18310249

Following gene: 18310246

Centisome position: 49.03

GC content: 32.37

Gene sequence:

>4068_bases
ATGCAATCATTTAACAAAAGGGGGACAGCTTTAGGAGCAGCAATTGCATTTGCTTTAACATTAGCGCCTACCTTAGTAAT
GGCTGAAACAAGACAAATTCCTGAATCTGAAACAGTAAATGTTGGATTCATAAAAGATGGAGAGAGATCAACAATATTCA
ATCAAAACTGGAAGTTTTTTAAGGGAGATCCTTCTGGTGCTGAAGGGGTAGACTTTGATGATTCTTCATGGAGAGGACTA
AACTTACCTCATGATTGGAGTATTGAAGGAGATTTTACTGTTGAAGGGGAAGCTGAAAGTGGATTCTTATTAGGAGGAAC
TGGATGGTATCGTAAAGCCTTTGTAGTTCCTGAAAAGTATAATAGTAAAGATTTTACATTAAACTTTGATGGAGTATATA
TGAATGCTGAAGTATATGTAAATGGTAAAAAGGTTGGTGAGCATAATTATGGATACACTTCTTTTGCCTTTGATATTACT
GAAGCTTTAATATGTGATGGACAAACTGAAAATATAATTGCTGTTAAGGTATCTAACCCAGTGCCAACTAGTAGATGGTA
TTCTGGAAGTGGAATTTATCGTGATGTAACTTTAAGTGTAACAGATTCTATTCATGTTGCACATTCAGGAACAACAGTTA
CTACTCCAAAACTTGAAGAGCAAAAAGGTGGAGACGTAGATGTAGCTATTGAGACAATTGTTGAAAACGAGTCCAAAGAT
AATTCTATGGTTACTGTAAAAAGCACAGTAGTAAATTCTAAGGGAGAAGAAGTTAGTGAGGCCGTAATAAATGAACAGAG
TATTGGAGTTAATGAAAGTTATACTTTCAAGCAAACTGCTATTGTAAATAATCCTGATTTATGGTCAGTTGATAATCCAA
ATATGTATAAGGTAAAAAGTGAAGTATTATTAGATGGAAAGGTTATAGATACTTATTTTACTGATTTTGGATTTAGATAT
TATAATTTTGATAAAGATACTGGATTCTCTTTAAATGGAGAAAATATGAAATTAAAAGGTGTTTGTATGCACCATGACCA
AGGGGCTTTAGGAGCAGCATCTTATTATCGTGCAGTAGAACGTCAAATGGAGAAAATGAAGGAAATGGGAGTAAATGCAA
TCCGTGTTTCTCATAATCCTGCTAGTGAAATGTTATTAGAGATTTGTAATCGTTTAGGTTTATTAGTTATTAATGAAGCC
TTTGATACATGGACAAATCCAAAGAACGGAAATGTAAATGACTTTTCTAAGTATTTTAATGAAGTAATAGGAGAAGATAA
TGAAATTTTAAATGGTTCTCCAGAAATGACATGGGGAGAGTTTGAAGCTAGATCTATGGTTAAAAACTCTAAGAACAATC
CATCTATAATAATGTGGTCAATAGGTAATGAGGTATTAGAAGGAATTAGTGGAAGTGCATCTAATTATACTAACGTAGCT
CAAAATATAATTGATTGGATTAAGGATGAGGATGAAACAAGACATGTTACTATAGGTGATAATAGAACTAAAAATGGAGA
TAGAACAGCAGAGGCTATTTCAGAGGTGGTTGATGACAATGGTGGATTAGTTGGATTTAACTATGCAAATGAGACACAGG
TTGCACAGCAAAGAGCAAACCATCCAGATTGGACATTATATGCTTCTGAAACCAGTAGTGCAATACACACTAGAGGATAT
TATAAAACAAAGGGAATAGATTATGGAAATCATCGTATTTCAGAGTATGATAATAATCAAACAAAAGTTGGTTGGGGACA
TTCAGCTAGTGATGCTTGGAAGTTTGTAATCAAAAATGATTATAATGCTGGAGAACTTGTTTGGACAGGATTTGACTATA
TAGGAGAACCTACTCCTTGGAATGGTACTGGTACAGGTACAGTTGGTGGAGGAAATGGAGCAGCTCCAAAATCAAGTTAC
TTTGGTATAGTTGATACTGCAGGATTTGAAAAAGATATTTATTATTTATATCAAAGTCAATGGAATGATGATGTAAATAC
ATTACATGTACTTCCAACATGGAATAGAGAAGATATAGTTATAGAAAATGGAAATGTTGAAGTAAACGTATTTACTGATG
CTCATAAAGTTGAATTATATCTAAATGATAAAAAAGTTGGAGAGCAAACCTCAACTGAGCATACAACTGATGCAGGATAC
AAATATTATACTTTTGGAAATGATTCATTGTATCCAGTATTTAATGTTCCTTATGAAGAGGGTACCTTAACTGCTAAGGC
TTATGATAAAGAAGGAAATGAAATCACAAATACAGAGGGAAGAAATACAGTAAAAACAACTGGGGAGGCTTCTACTGTAA
GATTAAGTGCAGATAGAGATACTATTGATTCAGATGGATATGATTTATCTTATATTACTGTAGATATTGTTGATGAAGAT
GGCAATATAGTTCAAAATGCAGATAATAGATTAAACTTCCAATTAGAAGGGGATGGAAAAATTGTAGGTGTTGACAATGG
AGATCAAACTGATACAGATTCTTATAAACCTACAAGTGATACAGAAGCTTCTAGAAAAGCATTAAGTGGTAAGGCATTAG
TAATAGTTCAATCAACTAAGGATGCTGGAAATATAAGATTAAATGTTTCAGGTGAGGGATTACAATCTCAATCTATAGAA
ATTAATACTGTAAATAATGCTGGAGAAGATAAGTTCTTAGAATCTTATGAAATAGTTAAAGATTACTATGTTAATTTAAA
TGAAAAGCCAGAGTTACCAAGTACAGTAGAAGGAAGATACAGTGATGGAACAACTGAGACTTTTAATATTTCATGGAATG
ATTATGATGAATCACAATTAAATACTCCTCAAGTATTTAAGATAAATGGTAAATTAGAAGGAACAGATGTGGCTGTAAAT
GTAAATGTCCATGTAATTGGTGATGTGGTTTCAATGGAAAATTACTCAACATTTACTTATGCTGGACAAACTCCAACACT
TCCTAAGACTGTTAAAGGATATTTAGCTGATGGAAATGAAAGTGAAGAGTTTAAAGTGGATTGGAATTTAGAAGGCGTAG
ATTTCTCTGAGCCTAATACAACAGTTGAAGTTTTAGGAGAAGTATCCTTATTAGGTAAGACATATACTGTTACTTCAACA
GTGCGTGTAGTTGAAGCTTTAAAAGCTGCTGCTAACTTAGCTATAAATAATTCTTCTAACAAAGATGTTCCTGCTTTAAG
CCAAAGTTGCGTTTCTACAGCTGATAACTTAAATTCTATTAATAATGGAATAACTAATAATAGTTCAAATACAGGAGAAC
GTTGGACAAACTGGAATGAAAGAAATTTAACAGAGAATGGTGAACCTAAAGGGGCATATGTTCAATTAGACTGGAAAAAC
AAATATAATATAGATAGACTAGATTTATGGTTATTTACTGATAATATTTATGGAAGAATTCCTAAGAAAGTTGAAATAAG
TTATAAAAATGAAGCTGGTGAATATGAGGTAGTTACTCATTCAAATACAACAGAGGTATCATACCTTGCTGGAGAAACAA
CTTATTTCTTAGATAAAGTAATAAATACTGATAGTATTCGTGTTTATATGCAACAACCTGAAGTAGGTAAGTGTATTGGA
TTATCAGAGGTTGCAGTATATGAGTATGTACCACAAGTAAGTGCTAATGAAGGTAATAAATTATCTGAAATAAAATTAGA
TGGCGAAGCCTTAGAAGGATTTAATCCTGATACTAATGAATATACAGTTAATTTAAAAGAATTACCTAAAACTGTAGAAG
CTTCAGGGGAAGAAAATGTGGCTATAACTATATTACCAGTTCATAATAATAAATCAATAATCATTGCTCGTTCAGAATCT
GGTGCTAAAAACATCTATACTGTAAATTATGTATTAGAAGAATCTGAAGGGTCAGCAGATATTAATGAGGATGGTTCTAT
AAATGTAGGAGATTTATCCATAGTATCTAAATATCAAGGAGAGGTTATATCAGGAAATGCTTTAAGTGAAAAATCTGATA
TAAACAAAGATGGAGTAGTAGATAAAGCTGATATCCAAATAGTTATGGGTAAGATCTTAGGAGAATAA

Upstream 100 bases:

>100_bases
TTATGACTTTACCATGAATTTACTTGATGGTATTATTATACATATAAGTTAAAATAAGTAAAATAGCTTATATGTATATT
TAAAAAGGGGGGGAATTAAT

Downstream 100 bases:

>100_bases
TCTTTTAAATAAAAAATAAGTTGTATAAAAGGGGGGTGTATCAAAGTATAATAATAAAACTTACTTTGATACACGTCTAT
TTTTATTGATTTCTAAAGGG

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 1355; Mature: 1355

Protein sequence:

>1355_residues
MQSFNKRGTALGAAIAFALTLAPTLVMAETRQIPESETVNVGFIKDGERSTIFNQNWKFFKGDPSGAEGVDFDDSSWRGL
NLPHDWSIEGDFTVEGEAESGFLLGGTGWYRKAFVVPEKYNSKDFTLNFDGVYMNAEVYVNGKKVGEHNYGYTSFAFDIT
EALICDGQTENIIAVKVSNPVPTSRWYSGSGIYRDVTLSVTDSIHVAHSGTTVTTPKLEEQKGGDVDVAIETIVENESKD
NSMVTVKSTVVNSKGEEVSEAVINEQSIGVNESYTFKQTAIVNNPDLWSVDNPNMYKVKSEVLLDGKVIDTYFTDFGFRY
YNFDKDTGFSLNGENMKLKGVCMHHDQGALGAASYYRAVERQMEKMKEMGVNAIRVSHNPASEMLLEICNRLGLLVINEA
FDTWTNPKNGNVNDFSKYFNEVIGEDNEILNGSPEMTWGEFEARSMVKNSKNNPSIIMWSIGNEVLEGISGSASNYTNVA
QNIIDWIKDEDETRHVTIGDNRTKNGDRTAEAISEVVDDNGGLVGFNYANETQVAQQRANHPDWTLYASETSSAIHTRGY
YKTKGIDYGNHRISEYDNNQTKVGWGHSASDAWKFVIKNDYNAGELVWTGFDYIGEPTPWNGTGTGTVGGGNGAAPKSSY
FGIVDTAGFEKDIYYLYQSQWNDDVNTLHVLPTWNREDIVIENGNVEVNVFTDAHKVELYLNDKKVGEQTSTEHTTDAGY
KYYTFGNDSLYPVFNVPYEEGTLTAKAYDKEGNEITNTEGRNTVKTTGEASTVRLSADRDTIDSDGYDLSYITVDIVDED
GNIVQNADNRLNFQLEGDGKIVGVDNGDQTDTDSYKPTSDTEASRKALSGKALVIVQSTKDAGNIRLNVSGEGLQSQSIE
INTVNNAGEDKFLESYEIVKDYYVNLNEKPELPSTVEGRYSDGTTETFNISWNDYDESQLNTPQVFKINGKLEGTDVAVN
VNVHVIGDVVSMENYSTFTYAGQTPTLPKTVKGYLADGNESEEFKVDWNLEGVDFSEPNTTVEVLGEVSLLGKTYTVTST
VRVVEALKAAANLAINNSSNKDVPALSQSCVSTADNLNSINNGITNNSSNTGERWTNWNERNLTENGEPKGAYVQLDWKN
KYNIDRLDLWLFTDNIYGRIPKKVEISYKNEAGEYEVVTHSNTTEVSYLAGETTYFLDKVINTDSIRVYMQQPEVGKCIG
LSEVAVYEYVPQVSANEGNKLSEIKLDGEALEGFNPDTNEYTVNLKELPKTVEASGEENVAITILPVHNNKSIIIARSES
GAKNIYTVNYVLEESEGSADINEDGSINVGDLSIVSKYQGEVISGNALSEKSDINKDGVVDKADIQIVMGKILGE

Sequences:

>Translated_1355_residues
MQSFNKRGTALGAAIAFALTLAPTLVMAETRQIPESETVNVGFIKDGERSTIFNQNWKFFKGDPSGAEGVDFDDSSWRGL
NLPHDWSIEGDFTVEGEAESGFLLGGTGWYRKAFVVPEKYNSKDFTLNFDGVYMNAEVYVNGKKVGEHNYGYTSFAFDIT
EALICDGQTENIIAVKVSNPVPTSRWYSGSGIYRDVTLSVTDSIHVAHSGTTVTTPKLEEQKGGDVDVAIETIVENESKD
NSMVTVKSTVVNSKGEEVSEAVINEQSIGVNESYTFKQTAIVNNPDLWSVDNPNMYKVKSEVLLDGKVIDTYFTDFGFRY
YNFDKDTGFSLNGENMKLKGVCMHHDQGALGAASYYRAVERQMEKMKEMGVNAIRVSHNPASEMLLEICNRLGLLVINEA
FDTWTNPKNGNVNDFSKYFNEVIGEDNEILNGSPEMTWGEFEARSMVKNSKNNPSIIMWSIGNEVLEGISGSASNYTNVA
QNIIDWIKDEDETRHVTIGDNRTKNGDRTAEAISEVVDDNGGLVGFNYANETQVAQQRANHPDWTLYASETSSAIHTRGY
YKTKGIDYGNHRISEYDNNQTKVGWGHSASDAWKFVIKNDYNAGELVWTGFDYIGEPTPWNGTGTGTVGGGNGAAPKSSY
FGIVDTAGFEKDIYYLYQSQWNDDVNTLHVLPTWNREDIVIENGNVEVNVFTDAHKVELYLNDKKVGEQTSTEHTTDAGY
KYYTFGNDSLYPVFNVPYEEGTLTAKAYDKEGNEITNTEGRNTVKTTGEASTVRLSADRDTIDSDGYDLSYITVDIVDED
GNIVQNADNRLNFQLEGDGKIVGVDNGDQTDTDSYKPTSDTEASRKALSGKALVIVQSTKDAGNIRLNVSGEGLQSQSIE
INTVNNAGEDKFLESYEIVKDYYVNLNEKPELPSTVEGRYSDGTTETFNISWNDYDESQLNTPQVFKINGKLEGTDVAVN
VNVHVIGDVVSMENYSTFTYAGQTPTLPKTVKGYLADGNESEEFKVDWNLEGVDFSEPNTTVEVLGEVSLLGKTYTVTST
VRVVEALKAAANLAINNSSNKDVPALSQSCVSTADNLNSINNGITNNSSNTGERWTNWNERNLTENGEPKGAYVQLDWKN
KYNIDRLDLWLFTDNIYGRIPKKVEISYKNEAGEYEVVTHSNTTEVSYLAGETTYFLDKVINTDSIRVYMQQPEVGKCIG
LSEVAVYEYVPQVSANEGNKLSEIKLDGEALEGFNPDTNEYTVNLKELPKTVEASGEENVAITILPVHNNKSIIIARSES
GAKNIYTVNYVLEESEGSADINEDGSINVGDLSIVSKYQGEVISGNALSEKSDINKDGVVDKADIQIVMGKILGE
>Mature_1355_residues
MQSFNKRGTALGAAIAFALTLAPTLVMAETRQIPESETVNVGFIKDGERSTIFNQNWKFFKGDPSGAEGVDFDDSSWRGL
NLPHDWSIEGDFTVEGEAESGFLLGGTGWYRKAFVVPEKYNSKDFTLNFDGVYMNAEVYVNGKKVGEHNYGYTSFAFDIT
EALICDGQTENIIAVKVSNPVPTSRWYSGSGIYRDVTLSVTDSIHVAHSGTTVTTPKLEEQKGGDVDVAIETIVENESKD
NSMVTVKSTVVNSKGEEVSEAVINEQSIGVNESYTFKQTAIVNNPDLWSVDNPNMYKVKSEVLLDGKVIDTYFTDFGFRY
YNFDKDTGFSLNGENMKLKGVCMHHDQGALGAASYYRAVERQMEKMKEMGVNAIRVSHNPASEMLLEICNRLGLLVINEA
FDTWTNPKNGNVNDFSKYFNEVIGEDNEILNGSPEMTWGEFEARSMVKNSKNNPSIIMWSIGNEVLEGISGSASNYTNVA
QNIIDWIKDEDETRHVTIGDNRTKNGDRTAEAISEVVDDNGGLVGFNYANETQVAQQRANHPDWTLYASETSSAIHTRGY
YKTKGIDYGNHRISEYDNNQTKVGWGHSASDAWKFVIKNDYNAGELVWTGFDYIGEPTPWNGTGTGTVGGGNGAAPKSSY
FGIVDTAGFEKDIYYLYQSQWNDDVNTLHVLPTWNREDIVIENGNVEVNVFTDAHKVELYLNDKKVGEQTSTEHTTDAGY
KYYTFGNDSLYPVFNVPYEEGTLTAKAYDKEGNEITNTEGRNTVKTTGEASTVRLSADRDTIDSDGYDLSYITVDIVDED
GNIVQNADNRLNFQLEGDGKIVGVDNGDQTDTDSYKPTSDTEASRKALSGKALVIVQSTKDAGNIRLNVSGEGLQSQSIE
INTVNNAGEDKFLESYEIVKDYYVNLNEKPELPSTVEGRYSDGTTETFNISWNDYDESQLNTPQVFKINGKLEGTDVAVN
VNVHVIGDVVSMENYSTFTYAGQTPTLPKTVKGYLADGNESEEFKVDWNLEGVDFSEPNTTVEVLGEVSLLGKTYTVTST
VRVVEALKAAANLAINNSSNKDVPALSQSCVSTADNLNSINNGITNNSSNTGERWTNWNERNLTENGEPKGAYVQLDWKN
KYNIDRLDLWLFTDNIYGRIPKKVEISYKNEAGEYEVVTHSNTTEVSYLAGETTYFLDKVINTDSIRVYMQQPEVGKCIG
LSEVAVYEYVPQVSANEGNKLSEIKLDGEALEGFNPDTNEYTVNLKELPKTVEASGEENVAITILPVHNNKSIIIARSES
GAKNIYTVNYVLEESEGSADINEDGSINVGDLSIVSKYQGEVISGNALSEKSDINKDGVVDKADIQIVMGKILGE

Specific function: The Wild-Type Enzyme Is An Ineffective Lactase. Two Classes Of Point Mutations Dramatically Improve Activity Of The Enzyme. [C]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=579, Percent_Identity=21.4162348877375, Blast_Score=83, Evalue=2e-15,
Organism=Escherichia coli, GI48994920, Length=411, Percent_Identity=27.2506082725061, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1786539, Length=411, Percent_Identity=27.9805352798054, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI1787903, Length=419, Percent_Identity=23.6276849642005, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17510825, Length=409, Percent_Identity=26.161369193154, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62471735, Length=435, Percent_Identity=23.6781609195402, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19922582, Length=435, Percent_Identity=23.6781609195402, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24655438, Length=435, Percent_Identity=23.6781609195402, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24651745, Length=460, Percent_Identity=22.6086956521739, Blast_Score=97, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 149641; Mature: 149641

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFNKRGTALGAAIAFALTLAPTLVMAETRQIPESETVNVGFIKDGERSTIFNQNWKFF
CCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCCEEEEEEECCCCCEEECCCCCEE
KGDPSGAEGVDFDDSSWRGLNLPHDWSIEGDFTVEGEAESGFLLGGTGWYRKAFVVPEKY
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEECCCC
NSKDFTLNFDGVYMNAEVYVNGKKVGEHNYGYTSFAFDITEALICDGQTENIIAVKVSNP
CCCEEEEEECCEEEEEEEEECCEEECCCCCCEEEEEHHHHHHEEECCCCCCEEEEEECCC
VPTSRWYSGSGIYRDVTLSVTDSIHVAHSGTTVTTPKLEEQKGGDVDVAIETIVENESKD
CCCCCEECCCCEEEEEEEEEECEEEEEECCCEEECCCCHHCCCCCEEEEEEEEECCCCCC
NSMVTVKSTVVNSKGEEVSEAVINEQSIGVNESYTFKQTAIVNNPDLWSVDNPNMYKVKS
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEECCCCCEEEEEE
EVLLDGKVIDTYFTDFGFRYYNFDKDTGFSLNGENMKLKGVCMHHDQGALGAASYYRAVE
EEEECCEEEEEHHHHCCEEEEECCCCCCCEECCCCEEEEEEEEECCCCCCHHHHHHHHHH
RQMEKMKEMGVNAIRVSHNPASEMLLEICNRLGLLVINEAFDTWTNPKNGNVNDFSKYFN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCHHHHHHHHH
EVIGEDNEILNGSPEMTWGEFEARSMVKNSKNNPSIIMWSIGNEVLEGISGSASNYTNVA
HHHCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHH
QNIIDWIKDEDETRHVTIGDNRTKNGDRTAEAISEVVDDNGGLVGFNYANETQVAQQRAN
HHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCC
HPDWTLYASETSSAIHTRGYYKTKGIDYGNHRISEYDNNQTKVGWGHSASDAWKFVIKND
CCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECC
YNAGELVWTGFDYIGEPTPWNGTGTGTVGGGNGAAPKSSYFGIVDTAGFEKDIYYLYQSQ
CCCCEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECC
WNDDVNTLHVLPTWNREDIVIENGNVEVNVFTDAHKVELYLNDKKVGEQTSTEHTTDAGY
CCCCCCEEEEEECCCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCE
KYYTFGNDSLYPVFNVPYEEGTLTAKAYDKEGNEITNTEGRNTVKTTGEASTVRLSADRD
EEEEECCCCCCEEEECCCCCCEEEEEEECCCCCEECCCCCCCEEEECCCCEEEEEECCCC
TIDSDGYDLSYITVDIVDEDGNIVQNADNRLNFQLEGDGKIVGVDNGDQTDTDSYKPTSD
CCCCCCEEEEEEEEEEECCCCCEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCC
TEASRKALSGKALVIVQSTKDAGNIRLNVSGEGLQSQSIEINTVNNAGEDKFLESYEIVK
CHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
DYYVNLNEKPELPSTVEGRYSDGTTETFNISWNDYDESQLNTPQVFKINGKLEGTDVAVN
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCEECCCEEEEE
VNVHVIGDVVSMENYSTFTYAGQTPTLPKTVKGYLADGNESEEFKVDWNLEGVDFSEPNT
EEEEEEEEEEECCCCCEEEECCCCCCCCHHHHHEECCCCCCCEEEEEEEECCCCCCCCCC
TVEVLGEVSLLGKTYTVTSTVRVVEALKAAANLAINNSSNKDVPALSQSCVSTADNLNSI
EEEEEEEHHHCCCEEEEHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHH
NNGITNNSSNTGERWTNWNERNLTENGEPKGAYVQLDWKNKYNIDRLDLWLFTDNIYGRI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCHHCCC
PKKVEISYKNEAGEYEVVTHSNTTEVSYLAGETTYFLDKVINTDSIRVYMQQPEVGKCIG
CCEEEEEECCCCCCEEEEECCCCCEEEEEECCHHEEHHHHCCCCEEEEEEECCCCCCCCC
LSEVAVYEYVPQVSANEGNKLSEIKLDGEALEGFNPDTNEYTVNLKELPKTVEASGEENV
CHHHHHHHHCCCCCCCCCCEEEEEEECCHHHCCCCCCCCEEEEEHHHCCHHHHCCCCCCE
AITILPVHNNKSIIIARSESGAKNIYTVNYVLEESEGSADINEDGSINVGDLSIVSKYQG
EEEEEEEECCCEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEHHCCC
EVISGNALSEKSDINKDGVVDKADIQIVMGKILGE
CEEECCCCCCCCCCCCCCCEEHHHHEEEEEHHHCC
>Mature Secondary Structure
MQSFNKRGTALGAAIAFALTLAPTLVMAETRQIPESETVNVGFIKDGERSTIFNQNWKFF
CCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCCEEEEEEECCCCCEEECCCCCEE
KGDPSGAEGVDFDDSSWRGLNLPHDWSIEGDFTVEGEAESGFLLGGTGWYRKAFVVPEKY
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEECCCC
NSKDFTLNFDGVYMNAEVYVNGKKVGEHNYGYTSFAFDITEALICDGQTENIIAVKVSNP
CCCEEEEEECCEEEEEEEEECCEEECCCCCCEEEEEHHHHHHEEECCCCCCEEEEEECCC
VPTSRWYSGSGIYRDVTLSVTDSIHVAHSGTTVTTPKLEEQKGGDVDVAIETIVENESKD
CCCCCEECCCCEEEEEEEEEECEEEEEECCCEEECCCCHHCCCCCEEEEEEEEECCCCCC
NSMVTVKSTVVNSKGEEVSEAVINEQSIGVNESYTFKQTAIVNNPDLWSVDNPNMYKVKS
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEECCCCCEEEEEE
EVLLDGKVIDTYFTDFGFRYYNFDKDTGFSLNGENMKLKGVCMHHDQGALGAASYYRAVE
EEEECCEEEEEHHHHCCEEEEECCCCCCCEECCCCEEEEEEEEECCCCCCHHHHHHHHHH
RQMEKMKEMGVNAIRVSHNPASEMLLEICNRLGLLVINEAFDTWTNPKNGNVNDFSKYFN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCHHHHHHHHH
EVIGEDNEILNGSPEMTWGEFEARSMVKNSKNNPSIIMWSIGNEVLEGISGSASNYTNVA
HHHCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCCCHHHHH
QNIIDWIKDEDETRHVTIGDNRTKNGDRTAEAISEVVDDNGGLVGFNYANETQVAQQRAN
HHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCC
HPDWTLYASETSSAIHTRGYYKTKGIDYGNHRISEYDNNQTKVGWGHSASDAWKFVIKND
CCCEEEEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECC
YNAGELVWTGFDYIGEPTPWNGTGTGTVGGGNGAAPKSSYFGIVDTAGFEKDIYYLYQSQ
CCCCEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECC
WNDDVNTLHVLPTWNREDIVIENGNVEVNVFTDAHKVELYLNDKKVGEQTSTEHTTDAGY
CCCCCCEEEEEECCCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCE
KYYTFGNDSLYPVFNVPYEEGTLTAKAYDKEGNEITNTEGRNTVKTTGEASTVRLSADRD
EEEEECCCCCCEEEECCCCCCEEEEEEECCCCCEECCCCCCCEEEECCCCEEEEEECCCC
TIDSDGYDLSYITVDIVDEDGNIVQNADNRLNFQLEGDGKIVGVDNGDQTDTDSYKPTSD
CCCCCCEEEEEEEEEEECCCCCEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCC
TEASRKALSGKALVIVQSTKDAGNIRLNVSGEGLQSQSIEINTVNNAGEDKFLESYEIVK
CHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
DYYVNLNEKPELPSTVEGRYSDGTTETFNISWNDYDESQLNTPQVFKINGKLEGTDVAVN
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCEECCCEEEEE
VNVHVIGDVVSMENYSTFTYAGQTPTLPKTVKGYLADGNESEEFKVDWNLEGVDFSEPNT
EEEEEEEEEEECCCCCEEEECCCCCCCCHHHHHEECCCCCCCEEEEEEEECCCCCCCCCC
TVEVLGEVSLLGKTYTVTSTVRVVEALKAAANLAINNSSNKDVPALSQSCVSTADNLNSI
EEEEEEEHHHCCCEEEEHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHH
NNGITNNSSNTGERWTNWNERNLTENGEPKGAYVQLDWKNKYNIDRLDLWLFTDNIYGRI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCHHCCC
PKKVEISYKNEAGEYEVVTHSNTTEVSYLAGETTYFLDKVINTDSIRVYMQQPEVGKCIG
CCEEEEEECCCCCCEEEEECCCCCEEEEEECCHHEEHHHHCCCCEEEEEEECCCCCCCCC
LSEVAVYEYVPQVSANEGNKLSEIKLDGEALEGFNPDTNEYTVNLKELPKTVEASGEENV
CHHHHHHHHCCCCCCCCCCEEEEEEECCHHHCCCCCCCCEEEEEHHHCCHHHHCCCCCCE
AITILPVHNNKSIIIARSESGAKNIYTVNYVLEESEGSADINEDGSINVGDLSIVSKYQG
EEEEEEEECCCEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEECCEEEEHHCCC
EVISGNALSEKSDINKDGVVDKADIQIVMGKILGE
CEEECCCCCCCCCCCCCCCEEHHHHEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA