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The map label for this gene is mprF [H]

Identifier: 18310229

GI number: 18310229

Start: 1452739

End: 1455294

Strand: Reverse

Name: mprF [H]

Synonym: CPE1247

Alternate gene names: 18310229

Gene position: 1455294-1452739 (Counterclockwise)

Preceding gene: 18310230

Following gene: 18310227

Centisome position: 48.01

GC content: 27.54

Gene sequence:

>2556_bases
GTGAAGTTAAATATAAAGATAAGTGACAAATTAAAATTATTTTTTAAGATAGCATTCGTTTCCGTAGTAATACTATTTAT
AGTTAGGGAATTTACTTCAGTATTTAAAAATTTCAACTCAGAATATTTCTTTATGTATAGAAATAAACTAGACTTTTTAA
ACCTATTAATAATTGCAGCATTAGGTATAATTTCTTACATTCCTTTATCTTTCTACGATTTTATTTTAAAGAGAAAAGTT
GGAATAAGATTAAAAAATAGAAAGCTATATAAGTATTCTTGGATAGCAAGTTCCATTGCAAGTTTACTTGGGTTTGGAGG
AGCTACATCCTTAGCTTTTAAACAGTATTTTTATGGTGACTATGTAGATGATAAAAAGAAATTATTAAAAGAAATTGGTA
AAATAGTAGCCTTAAACTTAACAGGCTTATCAATAGTTTGTTGTACATATATGGGGATTAGAATATCCTCTTGGAATAAC
CTAGGTATAATAAAATATGCCATAGGAATAATAGCTTTATATGCACCAGGATTTATAATTTACTCAGCTTATAAATATAG
CAAAACAAAGGACAAGTTAGAGTTTTTCAGTACCTTAGGTATTATATTCATATCATTTTTAGAGTGGCTTACAACGATAA
TTCTAATTTATGCTACTTTAAGAATAACAGGAGCATCAATAAGTGTTTTAACTTTCTTACCAATATATATTGAGGCAGCA
GTTGTTGGAATGATCAGTATGATTCCAGGGGGAATTGGTACCTTTGACTTAACTTTTATGACTGGATTAGAGGTCTTAGG
CATTCCTATAGAACAAACCCTATTAGTTATAATACTTTATAGAATAAGTTATTATATAGTTCCAGCTCTTATAGGTGTAT
TACTTTTTGTACATGATTTCGGTGGTAAAATAAACAAGAAGTTTAATGGATTACCTTATGAAATAGTTTCTAAGGTGGCT
TATAAGATAGTGGTTTCTTTAGTATTTATATCAGGAGCTATTATAGTTTTATCAAATATAGCACCTCAATATTTATTAAA
AATAAAATTATTAAAAGAAATTTTAGGTAAACAGGTATTAGGTTTATCAATTGGAATGAGCGTAGTATTAGGATTTTTAA
TAATGCTTGCAGCTCTTATGCTAAAATATAGGGCTAAAAGTATTTACAAAGCAAGTATGGTTTTATTTATATTAGGAATA
ATATTATCCTTAACAAAGGGAATTAATCCTTATGAATTAGTATTTTTAATTATTGTAGCTTACCTTTTATATTTAAGTAA
GAGAATGTTCTACAGGGATAGCTTTGTTGTAAGTTGTAAAAATACCTTAATAGATTCAGGTATATTAATTGCATCTTTTT
CAATTTATTTCTTTATTTTAATTACCTTTGGAACACATCTTAAATATGTAGGAATAGTTCGTAAAATGCCTTATAAGATG
GCATATAAATTTGGATTTATAGCCTTTGCTTTAGTAACTGTAATATATGTAGCTATTTACTTTTTAAATATAAGAAGAAA
AATTCCTGTTAAGACTTTTGATCAGTGTAGCGAATATGTGGAAAAGATAATAGAAGAATACAAGGGTGATTCTCTAACAC
ATTTAGTATTTTTAAAGGACAAGTATATTTATTTAAATGAAGATAAGGATCTTTTCATTCAATATGAAGTTTATGGAGAT
AAGCTTTTTGTTTTGGGAAATCCTGTTGGAAATAATGAAAATCTATTTAGGGAAATAGAAAAGTTTTGTGAGTATGCTGA
TAATTATGGTTACACACCAGTTTTTTACCAGGTTAATGATGAAATGATAAGTTACCTTCACTCTAATGGATATGATTTTA
TGAAAATTGGAGAAGAAGCTAAGGTTGATGTAAAAGAATTTAAAGTTGTAGGAAATAAAATGAAGAGTTTAAAAACTTCA
AGAAGTAAGGTCACTAAGGAAGGTTATACTTTCCACATGGTTGAACCACCTTTTTCAAAGGAATTTTTAGATTCCTTAAG
AGAAATATCAGATGAATGGTTAGATGGAAGAAAAGAAAAAGGATTTTCAGTGGGATTCTTTGATGAAGATTATTTAAATA
AAGCTCCTATAGCTATTTTAAAGGATAGAGAGGGAGAAATAAAAGCCTTTGCTAATATTATGTATATGTATGATAATGAA
AGCTTCTCAGTGGATTTAATGAGATTTAGTAAAAATACTCCAAGGGGAGTTATGGATTTTATGTTCATAAATTTAATTGA
GTATGGAAAAGAAAATGGCTATGAAATATTCAACATGGGAATGGCTCCTTTAGCAAATGTTGGTTTATCTAAATATGCTT
TCTGGAATGAAAAATTAGCCCTTCAATTCTATGAGAATGGACAAGCACTTTACTCCTTTAAAGGATTAAGACGTTTTAAA
GAGAAGTTTAGTCATAATTGGGAGTATAAATATATTGCTTACAGAAGAAATACATCTATACTAATAACAGTAATACAAGC
AGCTATAGTTTGTTCAAGAAACAGAAATGTAGATGAAAGTATAGTTGTAAGAAACTTAAAAAGCTTAATTAAATAA

Upstream 100 bases:

>100_bases
TTCTTACATTTTTGTAATGCAAATGAAATATTAATCAATGGATGTGAAGAAAGGTAAAGTGTATAATAAATTTGGATTTT
AAACATGGGGAGGACAAAAG

Downstream 100 bases:

>100_bases
AAAGTTGTATTTTAATATAGATTTAAAAGGACCAATTTTAGGTCCTTTTAATTTTATATTAAAATTATTGTTAATGTTAT
TTTTGATTTTTTGATTCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
MKLNIKISDKLKLFFKIAFVSVVILFIVREFTSVFKNFNSEYFFMYRNKLDFLNLLIIAALGIISYIPLSFYDFILKRKV
GIRLKNRKLYKYSWIASSIASLLGFGGATSLAFKQYFYGDYVDDKKKLLKEIGKIVALNLTGLSIVCCTYMGIRISSWNN
LGIIKYAIGIIALYAPGFIIYSAYKYSKTKDKLEFFSTLGIIFISFLEWLTTIILIYATLRITGASISVLTFLPIYIEAA
VVGMISMIPGGIGTFDLTFMTGLEVLGIPIEQTLLVIILYRISYYIVPALIGVLLFVHDFGGKINKKFNGLPYEIVSKVA
YKIVVSLVFISGAIIVLSNIAPQYLLKIKLLKEILGKQVLGLSIGMSVVLGFLIMLAALMLKYRAKSIYKASMVLFILGI
ILSLTKGINPYELVFLIIVAYLLYLSKRMFYRDSFVVSCKNTLIDSGILIASFSIYFFILITFGTHLKYVGIVRKMPYKM
AYKFGFIAFALVTVIYVAIYFLNIRRKIPVKTFDQCSEYVEKIIEEYKGDSLTHLVFLKDKYIYLNEDKDLFIQYEVYGD
KLFVLGNPVGNNENLFREIEKFCEYADNYGYTPVFYQVNDEMISYLHSNGYDFMKIGEEAKVDVKEFKVVGNKMKSLKTS
RSKVTKEGYTFHMVEPPFSKEFLDSLREISDEWLDGRKEKGFSVGFFDEDYLNKAPIAILKDREGEIKAFANIMYMYDNE
SFSVDLMRFSKNTPRGVMDFMFINLIEYGKENGYEIFNMGMAPLANVGLSKYAFWNEKLALQFYENGQALYSFKGLRRFK
EKFSHNWEYKYIAYRRNTSILITVIQAAIVCSRNRNVDESIVVRNLKSLIK

Sequences:

>Translated_851_residues
MKLNIKISDKLKLFFKIAFVSVVILFIVREFTSVFKNFNSEYFFMYRNKLDFLNLLIIAALGIISYIPLSFYDFILKRKV
GIRLKNRKLYKYSWIASSIASLLGFGGATSLAFKQYFYGDYVDDKKKLLKEIGKIVALNLTGLSIVCCTYMGIRISSWNN
LGIIKYAIGIIALYAPGFIIYSAYKYSKTKDKLEFFSTLGIIFISFLEWLTTIILIYATLRITGASISVLTFLPIYIEAA
VVGMISMIPGGIGTFDLTFMTGLEVLGIPIEQTLLVIILYRISYYIVPALIGVLLFVHDFGGKINKKFNGLPYEIVSKVA
YKIVVSLVFISGAIIVLSNIAPQYLLKIKLLKEILGKQVLGLSIGMSVVLGFLIMLAALMLKYRAKSIYKASMVLFILGI
ILSLTKGINPYELVFLIIVAYLLYLSKRMFYRDSFVVSCKNTLIDSGILIASFSIYFFILITFGTHLKYVGIVRKMPYKM
AYKFGFIAFALVTVIYVAIYFLNIRRKIPVKTFDQCSEYVEKIIEEYKGDSLTHLVFLKDKYIYLNEDKDLFIQYEVYGD
KLFVLGNPVGNNENLFREIEKFCEYADNYGYTPVFYQVNDEMISYLHSNGYDFMKIGEEAKVDVKEFKVVGNKMKSLKTS
RSKVTKEGYTFHMVEPPFSKEFLDSLREISDEWLDGRKEKGFSVGFFDEDYLNKAPIAILKDREGEIKAFANIMYMYDNE
SFSVDLMRFSKNTPRGVMDFMFINLIEYGKENGYEIFNMGMAPLANVGLSKYAFWNEKLALQFYENGQALYSFKGLRRFK
EKFSHNWEYKYIAYRRNTSILITVIQAAIVCSRNRNVDESIVVRNLKSLIK
>Mature_851_residues
MKLNIKISDKLKLFFKIAFVSVVILFIVREFTSVFKNFNSEYFFMYRNKLDFLNLLIIAALGIISYIPLSFYDFILKRKV
GIRLKNRKLYKYSWIASSIASLLGFGGATSLAFKQYFYGDYVDDKKKLLKEIGKIVALNLTGLSIVCCTYMGIRISSWNN
LGIIKYAIGIIALYAPGFIIYSAYKYSKTKDKLEFFSTLGIIFISFLEWLTTIILIYATLRITGASISVLTFLPIYIEAA
VVGMISMIPGGIGTFDLTFMTGLEVLGIPIEQTLLVIILYRISYYIVPALIGVLLFVHDFGGKINKKFNGLPYEIVSKVA
YKIVVSLVFISGAIIVLSNIAPQYLLKIKLLKEILGKQVLGLSIGMSVVLGFLIMLAALMLKYRAKSIYKASMVLFILGI
ILSLTKGINPYELVFLIIVAYLLYLSKRMFYRDSFVVSCKNTLIDSGILIASFSIYFFILITFGTHLKYVGIVRKMPYKM
AYKFGFIAFALVTVIYVAIYFLNIRRKIPVKTFDQCSEYVEKIIEEYKGDSLTHLVFLKDKYIYLNEDKDLFIQYEVYGD
KLFVLGNPVGNNENLFREIEKFCEYADNYGYTPVFYQVNDEMISYLHSNGYDFMKIGEEAKVDVKEFKVVGNKMKSLKTS
RSKVTKEGYTFHMVEPPFSKEFLDSLREISDEWLDGRKEKGFSVGFFDEDYLNKAPIAILKDREGEIKAFANIMYMYDNE
SFSVDLMRFSKNTPRGVMDFMFINLIEYGKENGYEIFNMGMAPLANVGLSKYAFWNEKLALQFYENGQALYSFKGLRRFK
EKFSHNWEYKYIAYRRNTSILITVIQAAIVCSRNRNVDESIVVRNLKSLIK

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 97831; Mature: 97831

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNIKISDKLKLFFKIAFVSVVILFIVREFTSVFKNFNSEYFFMYRNKLDFLNLLIIAA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHH
LGIISYIPLSFYDFILKRKVGIRLKNRKLYKYSWIASSIASLLGFGGATSLAFKQYFYGD
HHHHHHHHHHHHHHHHHHHHCCEEECCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
YVDDKKKLLKEIGKIVALNLTGLSIVCCTYMGIRISSWNNLGIIKYAIGIIALYAPGFII
CCCHHHHHHHHHHHEEEEEECCHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCEEE
YSAYKYSKTKDKLEFFSTLGIIFISFLEWLTTIILIYATLRITGASISVLTFLPIYIEAA
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VVGMISMIPGGIGTFDLTFMTGLEVLGIPIEQTLLVIILYRISYYIVPALIGVLLFVHDF
HHHHHHHCCCCCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKINKKFNGLPYEIVSKVAYKIVVSLVFISGAIIVLSNIAPQYLLKIKLLKEILGKQVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHH
GLSIGMSVVLGFLIMLAALMLKYRAKSIYKASMVLFILGIILSLTKGINPYELVFLIIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YLLYLSKRMFYRDSFVVSCKNTLIDSGILIASFSIYFFILITFGTHLKYVGIVRKMPYKM
HHHHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AYKFGFIAFALVTVIYVAIYFLNIRRKIPVKTFDQCSEYVEKIIEEYKGDSLTHLVFLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KYIYLNEDKDLFIQYEVYGDKLFVLGNPVGNNENLFREIEKFCEYADNYGYTPVFYQVND
EEEEEECCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECH
EMISYLHSNGYDFMKIGEEAKVDVKEFKVVGNKMKSLKTSRSKVTKEGYTFHMVEPPFSK
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
EFLDSLREISDEWLDGRKEKGFSVGFFDEDYLNKAPIAILKDREGEIKAFANIMYMYDNE
HHHHHHHHHHHHHHCCCCCCCCEECCCCHHHCCCCCEEEEECCCCCHHHHEEEEEEEECC
SFSVDLMRFSKNTPRGVMDFMFINLIEYGKENGYEIFNMGMAPLANVGLSKYAFWNEKLA
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCHHHEEECCCEE
LQFYENGQALYSFKGLRRFKEKFSHNWEYKYIAYRRNTSILITVIQAAIVCSRNRNVDES
EEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHH
IVVRNLKSLIK
HHHHHHHHHHC
>Mature Secondary Structure
MKLNIKISDKLKLFFKIAFVSVVILFIVREFTSVFKNFNSEYFFMYRNKLDFLNLLIIAA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHH
LGIISYIPLSFYDFILKRKVGIRLKNRKLYKYSWIASSIASLLGFGGATSLAFKQYFYGD
HHHHHHHHHHHHHHHHHHHHCCEEECCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
YVDDKKKLLKEIGKIVALNLTGLSIVCCTYMGIRISSWNNLGIIKYAIGIIALYAPGFII
CCCHHHHHHHHHHHEEEEEECCHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCCEEE
YSAYKYSKTKDKLEFFSTLGIIFISFLEWLTTIILIYATLRITGASISVLTFLPIYIEAA
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VVGMISMIPGGIGTFDLTFMTGLEVLGIPIEQTLLVIILYRISYYIVPALIGVLLFVHDF
HHHHHHHCCCCCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKINKKFNGLPYEIVSKVAYKIVVSLVFISGAIIVLSNIAPQYLLKIKLLKEILGKQVL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHH
GLSIGMSVVLGFLIMLAALMLKYRAKSIYKASMVLFILGIILSLTKGINPYELVFLIIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YLLYLSKRMFYRDSFVVSCKNTLIDSGILIASFSIYFFILITFGTHLKYVGIVRKMPYKM
HHHHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AYKFGFIAFALVTVIYVAIYFLNIRRKIPVKTFDQCSEYVEKIIEEYKGDSLTHLVFLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
KYIYLNEDKDLFIQYEVYGDKLFVLGNPVGNNENLFREIEKFCEYADNYGYTPVFYQVND
EEEEEECCCCEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECH
EMISYLHSNGYDFMKIGEEAKVDVKEFKVVGNKMKSLKTSRSKVTKEGYTFHMVEPPFSK
HHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
EFLDSLREISDEWLDGRKEKGFSVGFFDEDYLNKAPIAILKDREGEIKAFANIMYMYDNE
HHHHHHHHHHHHHHCCCCCCCCEECCCCHHHCCCCCEEEEECCCCCHHHHEEEEEEEECC
SFSVDLMRFSKNTPRGVMDFMFINLIEYGKENGYEIFNMGMAPLANVGLSKYAFWNEKLA
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCHHHEEECCCEE
LQFYENGQALYSFKGLRRFKEKFSHNWEYKYIAYRRNTSILITVIQAAIVCSRNRNVDES
EEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHH
IVVRNLKSLIK
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]