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The map label for this gene is yebQ [H]

Identifier: 18310220

GI number: 18310220

Start: 1445449

End: 1446897

Strand: Direct

Name: yebQ [H]

Synonym: CPE1238

Alternate gene names: 18310220

Gene position: 1445449-1446897 (Clockwise)

Preceding gene: 18310211

Following gene: 18310224

Centisome position: 47.68

GC content: 29.74

Gene sequence:

>1449_bases
GTGAATAATGCTAATGAAAACTCTAAAAACACTGAAGATTTAGTTTATAAAAACAGATGGTTTATATTAGCAGTATTAGT
AATGCAACCATTCATGGCATGTTTAGACAGTAGCATAGTTAATGTAGCCCTTCCAATTCTTCAAAAAGAACTTGGTGCAA
CTATGGCTGGAACTGAATGGATTGTAAGTTCATATTTAATAATAATTTCTGCATCAATTTTAATCTTTGGTAGATTAGGA
GATATGCATTCAAAAAGTTCAGTATTTATAAAAGGGATTTTAATATTTGTTCTTGGATCTTTCCTTTGCGGAATATCCCC
ATCACTTCCTATTCTAGTATTATCTAGAGTTGTGCAAGCTATTGGTGCCGCTATGTTAATGTCCACTAACCAAGGTATTA
TAACAGATGTTTTCCCTCCTAAGGAAAGAGGAAAAGCTTTAGGTATCTCTGGTTCCTTTGTTGCCTTAGGTTCTATATTA
GGTCCAGCATTAGGTGGATTCATAGTTACATATTTCACTTGGCACTATATTTTCTTAATAAATGTACCTATAGGTATAAT
TTGCTACATATTCGCTAAAAAATATCTACCAATAAGAATTCCTAAGGAATCTGAGTCAATGGATAAGCCTGGAGCAACAA
TGTTTTTCATTGCTACAATTCTTATATTTACATCAATATTAATTAGCCAACATTTAGGCTTTACTAGCATATATGTAATC
CTAGGATTAATAATTGGACTTATTATTCTTGCTTTATTCTTAATCTATGAAAACAAGATAAAGAATCCTATGCTTCATTT
AAGCTTATTTAAAAAGCCAATATTCTCAGTAAGCTTAATATGTGCATTTATTTCCTTTACTGCAATAAATACAATTAATG
TTATTCAACCCTTTTACTTAAATGACATTTTAGGCTATAGTCCTGGAAAAATTTCAGTTATAATGACAGCTTATCCAATT
GTATTATTTGTTATTGCACCACTTAGTGGAACATTATCAGATAAAATAGGAAGTAAAATACTTACTTTAATAGGATTATT
CTTAACAGGAGTTTCAATGATTTTATTATCATCATTAAATAGTAACTCAAGTGAAACATCCATATTCCTTATGTTATCTT
TATTAGGTTTTTCAAATGGATTATTCCAATCTCCAAATACAAACCTTATAATGTCCTCTGTTCCTAAGGATAAGCTTGGA
ATAGCAGGAGGTACTAATGCCTTAATAAGGAATTTAGGTCTTGCCTTTGGAGTATCAGCTTCAACCTCTATTTTATATGC
AAAAATGAGTAAGTTAGCTGGATTTAGAGTTTTAGGATCTGTTCCTAATAGACCTGATATATTTATTTCTGGAATGAGAT
TTGTATATATTTTAGTTGCTATTTCATGTTTTATATGCCTTATAATTTCTATAGCTGAATATATTCAATCTAAAAAAAAT
AACAAATAA

Upstream 100 bases:

>100_bases
TGAGTTTTTTCAATTTTGACAATAAAATTTTGTCGTTTTATAATTGTATAGTTAATGTTTAACAAAAATTTAATTAAAAT
TTAATAAAGGAGATGATTAG

Downstream 100 bases:

>100_bases
CAAAATAAAAGGTGCTGTATCAAAGATTTTATTAAAATCTACTTTGATACAGCACCTTTTTAATTATTACTTTCTTGTAT
GCTCATTATTCCTTGAGGAT

Product: multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNNANENSKNTEDLVYKNRWFILAVLVMQPFMACLDSSIVNVALPILQKELGATMAGTEWIVSSYLIIISASILIFGRLG
DMHSKSSVFIKGILIFVLGSFLCGISPSLPILVLSRVVQAIGAAMLMSTNQGIITDVFPPKERGKALGISGSFVALGSIL
GPALGGFIVTYFTWHYIFLINVPIGIICYIFAKKYLPIRIPKESESMDKPGATMFFIATILIFTSILISQHLGFTSIYVI
LGLIIGLIILALFLIYENKIKNPMLHLSLFKKPIFSVSLICAFISFTAINTINVIQPFYLNDILGYSPGKISVIMTAYPI
VLFVIAPLSGTLSDKIGSKILTLIGLFLTGVSMILLSSLNSNSSETSIFLMLSLLGFSNGLFQSPNTNLIMSSVPKDKLG
IAGGTNALIRNLGLAFGVSASTSILYAKMSKLAGFRVLGSVPNRPDIFISGMRFVYILVAISCFICLIISIAEYIQSKKN
NK

Sequences:

>Translated_482_residues
MNNANENSKNTEDLVYKNRWFILAVLVMQPFMACLDSSIVNVALPILQKELGATMAGTEWIVSSYLIIISASILIFGRLG
DMHSKSSVFIKGILIFVLGSFLCGISPSLPILVLSRVVQAIGAAMLMSTNQGIITDVFPPKERGKALGISGSFVALGSIL
GPALGGFIVTYFTWHYIFLINVPIGIICYIFAKKYLPIRIPKESESMDKPGATMFFIATILIFTSILISQHLGFTSIYVI
LGLIIGLIILALFLIYENKIKNPMLHLSLFKKPIFSVSLICAFISFTAINTINVIQPFYLNDILGYSPGKISVIMTAYPI
VLFVIAPLSGTLSDKIGSKILTLIGLFLTGVSMILLSSLNSNSSETSIFLMLSLLGFSNGLFQSPNTNLIMSSVPKDKLG
IAGGTNALIRNLGLAFGVSASTSILYAKMSKLAGFRVLGSVPNRPDIFISGMRFVYILVAISCFICLIISIAEYIQSKKN
NK
>Mature_482_residues
MNNANENSKNTEDLVYKNRWFILAVLVMQPFMACLDSSIVNVALPILQKELGATMAGTEWIVSSYLIIISASILIFGRLG
DMHSKSSVFIKGILIFVLGSFLCGISPSLPILVLSRVVQAIGAAMLMSTNQGIITDVFPPKERGKALGISGSFVALGSIL
GPALGGFIVTYFTWHYIFLINVPIGIICYIFAKKYLPIRIPKESESMDKPGATMFFIATILIFTSILISQHLGFTSIYVI
LGLIIGLIILALFLIYENKIKNPMLHLSLFKKPIFSVSLICAFISFTAINTINVIQPFYLNDILGYSPGKISVIMTAYPI
VLFVIAPLSGTLSDKIGSKILTLIGLFLTGVSMILLSSLNSNSSETSIFLMLSLLGFSNGLFQSPNTNLIMSSVPKDKLG
IAGGTNALIRNLGLAFGVSASTSILYAKMSKLAGFRVLGSVPNRPDIFISGMRFVYILVAISCFICLIISIAEYIQSKKN
NK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=415, Percent_Identity=33.4939759036145, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1790195, Length=409, Percent_Identity=27.1393643031785, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788710, Length=438, Percent_Identity=28.9954337899543, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789042, Length=412, Percent_Identity=25.2427184466019, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788392, Length=314, Percent_Identity=28.9808917197452, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790146, Length=189, Percent_Identity=24.8677248677249, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082231, Length=341, Percent_Identity=20.2346041055718, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1788509, Length=136, Percent_Identity=22.7941176470588, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=283, Percent_Identity=26.8551236749117, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=179, Percent_Identity=26.8156424581006, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324264, Length=165, Percent_Identity=28.4848484848485, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322958, Length=185, Percent_Identity=28.1081081081081, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323520, Length=293, Percent_Identity=26.2798634812287, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52315; Mature: 52315

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNANENSKNTEDLVYKNRWFILAVLVMQPFMACLDSSIVNVALPILQKELGATMAGTEW
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IVSSYLIIISASILIFGRLGDMHSKSSVFIKGILIFVLGSFLCGISPSLPILVLSRVVQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IGAAMLMSTNQGIITDVFPPKERGKALGISGSFVALGSILGPALGGFIVTYFTWHYIFLI
HHHHHHHCCCCCCEECCCCCHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVPIGIICYIFAKKYLPIRIPKESESMDKPGATMFFIATILIFTSILISQHLGFTSIYVI
HHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LGLIIGLIILALFLIYENKIKNPMLHLSLFKKPIFSVSLICAFISFTAINTINVIQPFYL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
NDILGYSPGKISVIMTAYPIVLFVIAPLSGTLSDKIGSKILTLIGLFLTGVSMILLSSLN
HHHHCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SNSSETSIFLMLSLLGFSNGLFQSPNTNLIMSSVPKDKLGIAGGTNALIRNLGLAFGVSA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHCCCCCCHHHHHHHHHHHHCCCC
STSILYAKMSKLAGFRVLGSVPNRPDIFISGMRFVYILVAISCFICLIISIAEYIQSKKN
HHHHHHHHHHHHHCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NK
CC
>Mature Secondary Structure
MNNANENSKNTEDLVYKNRWFILAVLVMQPFMACLDSSIVNVALPILQKELGATMAGTEW
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IVSSYLIIISASILIFGRLGDMHSKSSVFIKGILIFVLGSFLCGISPSLPILVLSRVVQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IGAAMLMSTNQGIITDVFPPKERGKALGISGSFVALGSILGPALGGFIVTYFTWHYIFLI
HHHHHHHCCCCCCEECCCCCHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVPIGIICYIFAKKYLPIRIPKESESMDKPGATMFFIATILIFTSILISQHLGFTSIYVI
HHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LGLIIGLIILALFLIYENKIKNPMLHLSLFKKPIFSVSLICAFISFTAINTINVIQPFYL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
NDILGYSPGKISVIMTAYPIVLFVIAPLSGTLSDKIGSKILTLIGLFLTGVSMILLSSLN
HHHHCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SNSSETSIFLMLSLLGFSNGLFQSPNTNLIMSSVPKDKLGIAGGTNALIRNLGLAFGVSA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHCCCCCCHHHHHHHHHHHHCCCC
STSILYAKMSKLAGFRVLGSVPNRPDIFISGMRFVYILVAISCFICLIISIAEYIQSKKN
HHHHHHHHHHHHHCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]