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The map label for this gene is cbiL [H]

Identifier: 18310205

GI number: 18310205

Start: 1426510

End: 1427172

Strand: Reverse

Name: cbiL [H]

Synonym: CPE1223

Alternate gene names: 18310205

Gene position: 1427172-1426510 (Counterclockwise)

Preceding gene: 18310206

Following gene: 18310204

Centisome position: 47.08

GC content: 31.22

Gene sequence:

>663_bases
ATGGCAATATTATATGGAATAGGTGTAGGACCAGGAGATAGTGAACTATTAACAATAAAGGCAGTAAAGGCTATTGAAAA
TAGTGATGTTATAGTAGCACCAAGTGCAGAAGAAGGTGGAGAGAGCATAGCATTAATAGCAGCTCAGGAATACATAAAAG
AAGGAACAGAAATAGCTGTTAAACATTTCCCAATGGGAAAGAAAAACAGAGAATTAAAAGTTAAAGAGGCTTATGACTTT
ATTTTAGAAAAACTTAAAGAAGGAAAAAATGTAAGTTTCTTAACTATAGGGGATCCTTATGTTTATAGTACTTATATACA
TTTATTAAATTATGTAGAAGACCATGGTTTCCATGTAAAAACTATTCCAGGAATAACATCTTTCTGTGCTGCAGCTAGCA
TAGTTGATAGAACATTAGTTGTAGGTAATGAACCATTACTTGTTCTGCCAGCAGGTAGAGTACATGACATAAAAGATGAA
AAGTTCGTTGTAATAATGAAAGTTTATAAAAAAGAAGAAGAAGTTTTAGATGTTTTAGAAGAAAAAGGATTTGATTATGT
TCTAGTTAGTAGAGCAGGTAGAGAAGGGGAAAAAGTTTTAAAAACTAGAGAAGAAATCTTAAATCATAGAGATTACATGT
CTTTAATACTAGCAAGTAAATAG

Upstream 100 bases:

>100_bases
AAATTTCTTTAGTTAACATAAGTAAAAATAGAGAAAATACATACATGATGATTAGCAATAATCCAATTTTTATTGTTAAG
GCATTTAAGGAGGAAAATTA

Downstream 100 bases:

>100_bases
AGAAAAATTATAAATAAAAAATCGTATTTTATTAGGAGGCAAAGGATAAAATGTTATATTTTATAGGTGCAGGTCCAGGA
GCTGTTGATTTAATAACTGT

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MAILYGIGVGPGDSELLTIKAVKAIENSDVIVAPSAEEGGESIALIAAQEYIKEGTEIAVKHFPMGKKNRELKVKEAYDF
ILEKLKEGKNVSFLTIGDPYVYSTYIHLLNYVEDHGFHVKTIPGITSFCAAASIVDRTLVVGNEPLLVLPAGRVHDIKDE
KFVVIMKVYKKEEEVLDVLEEKGFDYVLVSRAGREGEKVLKTREEILNHRDYMSLILASK

Sequences:

>Translated_220_residues
MAILYGIGVGPGDSELLTIKAVKAIENSDVIVAPSAEEGGESIALIAAQEYIKEGTEIAVKHFPMGKKNRELKVKEAYDF
ILEKLKEGKNVSFLTIGDPYVYSTYIHLLNYVEDHGFHVKTIPGITSFCAAASIVDRTLVVGNEPLLVLPAGRVHDIKDE
KFVVIMKVYKKEEEVLDVLEEKGFDYVLVSRAGREGEKVLKTREEILNHRDYMSLILASK
>Mature_219_residues
AILYGIGVGPGDSELLTIKAVKAIENSDVIVAPSAEEGGESIALIAAQEYIKEGTEIAVKHFPMGKKNRELKVKEAYDFI
LEKLKEGKNVSFLTIGDPYVYSTYIHLLNYVEDHGFHVKTIPGITSFCAAASIVDRTLVVGNEPLLVLPAGRVHDIKDEK
FVVIMKVYKKEEEVLDVLEEKGFDYVLVSRAGREGEKVLKTREEILNHRDYMSLILASK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 24454; Mature: 24322

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILYGIGVGPGDSELLTIKAVKAIENSDVIVAPSAEEGGESIALIAAQEYIKEGTEIAV
CEEEEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEEEHHHHHHCCCEEEE
KHFPMGKKNRELKVKEAYDFILEKLKEGKNVSFLTIGDPYVYSTYIHLLNYVEDHGFHVK
EECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEE
TIPGITSFCAAASIVDRTLVVGNEPLLVLPAGRVHDIKDEKFVVIMKVYKKEEEVLDVLE
ECCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCEEEEEEHHCCHHHHHHHHH
EKGFDYVLVSRAGREGEKVLKTREEILNHRDYMSLILASK
HCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHCCCC
>Mature Secondary Structure 
AILYGIGVGPGDSELLTIKAVKAIENSDVIVAPSAEEGGESIALIAAQEYIKEGTEIAV
EEEEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCEEEEEEHHHHHHCCCEEEE
KHFPMGKKNRELKVKEAYDFILEKLKEGKNVSFLTIGDPYVYSTYIHLLNYVEDHGFHVK
EECCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEE
TIPGITSFCAAASIVDRTLVVGNEPLLVLPAGRVHDIKDEKFVVIMKVYKKEEEVLDVLE
ECCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCEEEEEEHHCCHHHHHHHHH
EKGFDYVLVSRAGREGEKVLKTREEILNHRDYMSLILASK
HCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]