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The map label for this gene is mepA [H]

Identifier: 18310181

GI number: 18310181

Start: 1400875

End: 1401852

Strand: Reverse

Name: mepA [H]

Synonym: CPE1199

Alternate gene names: 18310181

Gene position: 1401852-1400875 (Counterclockwise)

Preceding gene: 18310182

Following gene: 18310180

Centisome position: 46.24

GC content: 31.39

Gene sequence:

>978_bases
ATGGTGAATAGTATGAGCAAAAAAGAAACAGATTTAGGAAGGGATAGTATTGGAAAGCTCCTTTTTAAACTAGCTATGCC
AGCTATAATAGCTCAACTTGTTAATGTTTTATACAATATAGTAGATAGAATGTTTATAGGAAGATTGCAATCTGGTGATA
TGGCTATGGCTGGAGTTGGGGTAGCCTTTCCAATTATAATGATAGTCGCTGCTTTTAGTGGCTTAGTTGGTATGGGAGGA
GCTCCCTTAGCAGCGATTAAAATGGGAGAAAAGAAAAAAGAAGATGCTGAAGAAATAATGACAAATAGTTTTTCTGCACT
TATAGGATTAGCTTTATTTTTAACAGTATTTTTCTTTATATTTAAGGAGCCAATTTTATGGGCCTTTGGGGCTAGTGATG
CAACTATAGGATATGCTTTAGATTATTTAGGTATTTATTTAGTAGGTACTATATTTGTTCAAATTGCCTTAGGAATGAAT
TCCTTTATAAATACTCAAGGATTTGCTAAGGTTGGAATGATAACAGTTATGGTAGGAGCTATAATAAATATTGTATTAGA
TCCTATTTTAATCTTTGGATTTAATATGGGAGTTAAGGGAGCAGCTTTAGCAACTATAATTGGTCAATGCGCCTCTGCTA
TATGGGTATTATACTTTTTATTTGGAAAACAAAGTATTCTTAGAATAAGAAAAAAATTCTTAAAGCCAAAATTAAAAATA
TTATTTTCAATAATGGCTTTAGGAGTATCTCCATTTATAATGCAAGCTACTGAAAGCTTAGTCATAATAAGTATGAATAA
TAATTTATTAAAGTATGGTGGAGACTTAGCCGTTGGAGCAATGACTATTATGAGTAGTGTAATGCAAATAATATTACTTC
CATTAATGGGACTTTCTCAAGGGGCACAACCTATAATAAGTTATAACTATGGGGCTAATAAAGTCTATAGAGTAAAAAAG
CCTTTAAATTACTTTTAG

Upstream 100 bases:

>100_bases
CTAATATGGAATTTAGACACTGTTTAAAATGTACAAGTAATAAATGTTATTGTATGAATCATATAAAAAATCATGAGCAT
AAATAAAATTAGGGGAAAGA

Downstream 100 bases:

>100_bases
TATCATCAATGGTATTTACCACAATTATGTGGAGTGCATTAATGATTTTACCAGATGTGTTTGTAAAGATTTTTAATAGC
AATAATCCTCAATTAATGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MVNSMSKKETDLGRDSIGKLLFKLAMPAIIAQLVNVLYNIVDRMFIGRLQSGDMAMAGVGVAFPIIMIVAAFSGLVGMGG
APLAAIKMGEKKKEDAEEIMTNSFSALIGLALFLTVFFFIFKEPILWAFGASDATIGYALDYLGIYLVGTIFVQIALGMN
SFINTQGFAKVGMITVMVGAIINIVLDPILIFGFNMGVKGAALATIIGQCASAIWVLYFLFGKQSILRIRKKFLKPKLKI
LFSIMALGVSPFIMQATESLVIISMNNNLLKYGGDLAVGAMTIMSSVMQIILLPLMGLSQGAQPIISYNYGANKVYRVKK
PLNYF

Sequences:

>Translated_325_residues
MVNSMSKKETDLGRDSIGKLLFKLAMPAIIAQLVNVLYNIVDRMFIGRLQSGDMAMAGVGVAFPIIMIVAAFSGLVGMGG
APLAAIKMGEKKKEDAEEIMTNSFSALIGLALFLTVFFFIFKEPILWAFGASDATIGYALDYLGIYLVGTIFVQIALGMN
SFINTQGFAKVGMITVMVGAIINIVLDPILIFGFNMGVKGAALATIIGQCASAIWVLYFLFGKQSILRIRKKFLKPKLKI
LFSIMALGVSPFIMQATESLVIISMNNNLLKYGGDLAVGAMTIMSSVMQIILLPLMGLSQGAQPIISYNYGANKVYRVKK
PLNYF
>Mature_325_residues
MVNSMSKKETDLGRDSIGKLLFKLAMPAIIAQLVNVLYNIVDRMFIGRLQSGDMAMAGVGVAFPIIMIVAAFSGLVGMGG
APLAAIKMGEKKKEDAEEIMTNSFSALIGLALFLTVFFFIFKEPILWAFGASDATIGYALDYLGIYLVGTIFVQIALGMN
SFINTQGFAKVGMITVMVGAIINIVLDPILIFGFNMGVKGAALATIIGQCASAIWVLYFLFGKQSILRIRKKFLKPKLKI
LFSIMALGVSPFIMQATESLVIISMNNNLLKYGGDLAVGAMTIMSSVMQIILLPLMGLSQGAQPIISYNYGANKVYRVKK
PLNYF

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 35183; Mature: 35183

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNSMSKKETDLGRDSIGKLLFKLAMPAIIAQLVNVLYNIVDRMFIGRLQSGDMAMAGVG
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VAFPIIMIVAAFSGLVGMGGAPLAAIKMGEKKKEDAEEIMTNSFSALIGLALFLTVFFFI
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKEPILWAFGASDATIGYALDYLGIYLVGTIFVQIALGMNSFINTQGFAKVGMITVMVGA
HHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IINIVLDPILIFGFNMGVKGAALATIIGQCASAIWVLYFLFGKQSILRIRKKFLKPKLKI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LFSIMALGVSPFIMQATESLVIISMNNNLLKYGGDLAVGAMTIMSSVMQIILLPLMGLSQ
HHHHHHHCCCHHHHHCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GAQPIISYNYGANKVYRVKKPLNYF
CCCCEEEECCCCCCEEEECCCCCCC
>Mature Secondary Structure
MVNSMSKKETDLGRDSIGKLLFKLAMPAIIAQLVNVLYNIVDRMFIGRLQSGDMAMAGVG
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VAFPIIMIVAAFSGLVGMGGAPLAAIKMGEKKKEDAEEIMTNSFSALIGLALFLTVFFFI
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKEPILWAFGASDATIGYALDYLGIYLVGTIFVQIALGMNSFINTQGFAKVGMITVMVGA
HHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IINIVLDPILIFGFNMGVKGAALATIIGQCASAIWVLYFLFGKQSILRIRKKFLKPKLKI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LFSIMALGVSPFIMQATESLVIISMNNNLLKYGGDLAVGAMTIMSSVMQIILLPLMGLSQ
HHHHHHHCCCHHHHHCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GAQPIISYNYGANKVYRVKKPLNYF
CCCCEEEECCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA