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The map label for this gene is murC [H]

Identifier: 18310170

GI number: 18310170

Start: 1384439

End: 1385794

Strand: Direct

Name: murC [H]

Synonym: CPE1188

Alternate gene names: 18310170

Gene position: 1384439-1385794 (Clockwise)

Preceding gene: 18310157

Following gene: 18310171

Centisome position: 45.67

GC content: 28.24

Gene sequence:

>1356_bases
GTGTTTAAAATAGCTATTAAATCTTATCTAAGCATAATCTTATCTAAAATGACACAATTTATTTCAAAGAAAGTTTTTAA
AGGTGGAACTAACTTTCCAGGTAAAGTAGCTTTAAAAATCGATAGAAACATTTTAAAAGTAGTTTCTAAAAATTATAAAG
TTATTTTAGTTACTGGAACTAATGGAAAGACTACTACTACTTCAATGATATATAATGTCCTTAAAGGTAATGGATTAGAT
GTTATAACTAATGCTACTGGAGCAAATCTTTATCCAGGAATAGTTAGTACCTTCGTAGCTAATTACAAATTCTCTTCAAA
TAAAGAAAGATATGCAGTAATTGAAGTTGATGAAGCTAACTTAAAATTTATAACAGAGTATATAACTCCAGAAATAATAA
CTGTAACTAATCTTTTCAGAGATCAGTTAGATAGATATGGGGAGGTTTATACTACTCTAAATAAAATATTAGAAGGAGTT
GTTAAAGTACCAAGTACTACTCTTCTTTTAAATGGAGATGAATCTTTATTAGGAAGACTTGATGTTAAAAATCCTAAAGT
TTATTATGGATTCAAAGTTTCTCCAAATAAAAACAAGAATATAGAAATTAATGCTGATGCTAAGTTCTGTAAGTTCTGTA
AAGAGCCTTATTCTTATAACTTTATAACATACAATCATCTTGGAAGTTTCTATTGTCCTAACTGTGGATTCAAAAGAGAA
GATTTAAAATATAAAGTAGAAGAAATAGTAGAACTTACCCCTGAAAGTTCTAAGGTTGTTATAAATGGTGGTTTATTTAC
AATAACTCAACCTGGTACTTATAATATATACAACGGATTATGTGCTTATTCTGTTGCAAAAGAATTACATATTAATGATG
AAGTTATTCAAAAATCATTCTCTAATCAAAGTTCATCCTTTGGAAGACAGGAAACAATAAAAATTGGAGATAAGGAAGCT
AGAATTATCTTGGTTAAAAATCCAGCTGGATATAATCAAGCCTTAGATACTCTTCTTCTAAATTCAGAAAGCTTTGCTGC
AGCATTCTTATTAAATGATAATTATGCAGATGGTAAGGATGTTTCTTGGATCTGGGATGTTGATTTTGAAAAATTAAATT
CAATGGACTTAAATGAAATATTTATCTCTGGAATGAGAGCTTATGATATGGCTGTAAGATTGAAAATTGCTAATCTACCA
GTTGAAAAGTTTTTAATAAAGGAAGATTTTGAAGGCTTAACAGAGGCAATCAAAAATTCTAAGGAAAACAAGGTTTATAT
CCTTGCAACTTATACTGCTATGATTAACTATAGAAAATACTTACATTCCAAAGGTTATATTGATAAGCTTTGGTAG

Upstream 100 bases:

>100_bases
TCCCTACTTATTATTAATAAATTACTATATTGGTAAATTAAATACTTTGTGCTATACTATAATAGTTTAAGAAGATTGAC
TAAAAAGTAATTGTAAGGTG

Downstream 100 bases:

>100_bases
TTAAAGGAGAGATTCATATGGAATTAAATATATGTCACTTATATCCTGATCTACTTAATGTTTATGGAGATGTAGGAAAT
ATTTTAATATTAAAGCATAG

Product: UDP-N-acetylmuramyl tripeptide synthetase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MFKIAIKSYLSIILSKMTQFISKKVFKGGTNFPGKVALKIDRNILKVVSKNYKVILVTGTNGKTTTTSMIYNVLKGNGLD
VITNATGANLYPGIVSTFVANYKFSSNKERYAVIEVDEANLKFITEYITPEIITVTNLFRDQLDRYGEVYTTLNKILEGV
VKVPSTTLLLNGDESLLGRLDVKNPKVYYGFKVSPNKNKNIEINADAKFCKFCKEPYSYNFITYNHLGSFYCPNCGFKRE
DLKYKVEEIVELTPESSKVVINGGLFTITQPGTYNIYNGLCAYSVAKELHINDEVIQKSFSNQSSSFGRQETIKIGDKEA
RIILVKNPAGYNQALDTLLLNSESFAAAFLLNDNYADGKDVSWIWDVDFEKLNSMDLNEIFISGMRAYDMAVRLKIANLP
VEKFLIKEDFEGLTEAIKNSKENKVYILATYTAMINYRKYLHSKGYIDKLW

Sequences:

>Translated_451_residues
MFKIAIKSYLSIILSKMTQFISKKVFKGGTNFPGKVALKIDRNILKVVSKNYKVILVTGTNGKTTTTSMIYNVLKGNGLD
VITNATGANLYPGIVSTFVANYKFSSNKERYAVIEVDEANLKFITEYITPEIITVTNLFRDQLDRYGEVYTTLNKILEGV
VKVPSTTLLLNGDESLLGRLDVKNPKVYYGFKVSPNKNKNIEINADAKFCKFCKEPYSYNFITYNHLGSFYCPNCGFKRE
DLKYKVEEIVELTPESSKVVINGGLFTITQPGTYNIYNGLCAYSVAKELHINDEVIQKSFSNQSSSFGRQETIKIGDKEA
RIILVKNPAGYNQALDTLLLNSESFAAAFLLNDNYADGKDVSWIWDVDFEKLNSMDLNEIFISGMRAYDMAVRLKIANLP
VEKFLIKEDFEGLTEAIKNSKENKVYILATYTAMINYRKYLHSKGYIDKLW
>Mature_451_residues
MFKIAIKSYLSIILSKMTQFISKKVFKGGTNFPGKVALKIDRNILKVVSKNYKVILVTGTNGKTTTTSMIYNVLKGNGLD
VITNATGANLYPGIVSTFVANYKFSSNKERYAVIEVDEANLKFITEYITPEIITVTNLFRDQLDRYGEVYTTLNKILEGV
VKVPSTTLLLNGDESLLGRLDVKNPKVYYGFKVSPNKNKNIEINADAKFCKFCKEPYSYNFITYNHLGSFYCPNCGFKRE
DLKYKVEEIVELTPESSKVVINGGLFTITQPGTYNIYNGLCAYSVAKELHINDEVIQKSFSNQSSSFGRQETIKIGDKEA
RIILVKNPAGYNQALDTLLLNSESFAAAFLLNDNYADGKDVSWIWDVDFEKLNSMDLNEIFISGMRAYDMAVRLKIANLP
VEKFLIKEDFEGLTEAIKNSKENKVYILATYTAMINYRKYLHSKGYIDKLW

Specific function: Cell wall formation [H]

COG id: COG0769

COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 51057; Mature: 51057

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01011 FOLYLPOLYGLU_SYNT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKIAIKSYLSIILSKMTQFISKKVFKGGTNFPGKVALKIDRNILKVVSKNYKVILVTGT
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEEEEECC
NGKTTTTSMIYNVLKGNGLDVITNATGANLYPGIVSTFVANYKFSSNKERYAVIEVDEAN
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCEECCCCCEEEEEEECCCC
LKFITEYITPEIITVTNLFRDQLDRYGEVYTTLNKILEGVVKVPSTTLLLNGDESLLGRL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHEEE
DVKNPKVYYGFKVSPNKNKNIEINADAKFCKFCKEPYSYNFITYNHLGSFYCPNCGFKRE
ECCCCEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCCCEEECCCCCEECCCCCCCHH
DLKYKVEEIVELTPESSKVVINGGLFTITQPGTYNIYNGLCAYSVAKELHINDEVIQKSF
HHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SNQSSSFGRQETIKIGDKEARIILVKNPAGYNQALDTLLLNSESFAAAFLLNDNYADGKD
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCC
VSWIWDVDFEKLNSMDLNEIFISGMRAYDMAVRLKIANLPVEKFLIKEDFEGLTEAIKNS
CEEEEECCHHHHCCCCHHHHHHHCHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
KENKVYILATYTAMINYRKYLHSKGYIDKLW
CCCEEEEEEEHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MFKIAIKSYLSIILSKMTQFISKKVFKGGTNFPGKVALKIDRNILKVVSKNYKVILVTGT
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHCCCCEEEEEECC
NGKTTTTSMIYNVLKGNGLDVITNATGANLYPGIVSTFVANYKFSSNKERYAVIEVDEAN
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCEECCCCCEEEEEEECCCC
LKFITEYITPEIITVTNLFRDQLDRYGEVYTTLNKILEGVVKVPSTTLLLNGDESLLGRL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHEEE
DVKNPKVYYGFKVSPNKNKNIEINADAKFCKFCKEPYSYNFITYNHLGSFYCPNCGFKRE
ECCCCEEEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCCCEEECCCCCEECCCCCCCHH
DLKYKVEEIVELTPESSKVVINGGLFTITQPGTYNIYNGLCAYSVAKELHINDEVIQKSF
HHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SNQSSSFGRQETIKIGDKEARIILVKNPAGYNQALDTLLLNSESFAAAFLLNDNYADGKD
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCC
VSWIWDVDFEKLNSMDLNEIFISGMRAYDMAVRLKIANLPVEKFLIKEDFEGLTEAIKNS
CEEEEECCHHHHCCCCHHHHHHHCHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
KENKVYILATYTAMINYRKYLHSKGYIDKLW
CCCEEEEEEEHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA