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The map label for this gene is cilB [H]

Identifier: 18310130

GI number: 18310130

Start: 1341618

End: 1342508

Strand: Direct

Name: cilB [H]

Synonym: CPE1148

Alternate gene names: 18310130

Gene position: 1341618-1342508 (Clockwise)

Preceding gene: 18310129

Following gene: 18310131

Centisome position: 44.26

GC content: 33.67

Gene sequence:

>891_bases
ATGCCAAGATTAAGAAGATCAATGATGTTTGTACCTGGAAGTAAGCCTGCTATGATAAGAGATTGTACTATATATGGTGC
TGATTCCGTAATGTTTGACTTAGAAGACTCAGTTTCTATAGCAGAAAAAGATTCTGCAAGAAGATTAGTTTATCATGCCT
TAACATCTATGGATTTTGGAGATACAGAAACAGTAGTCCGTGTTAATGCTTTAGATTCAGAGTTTGGTATTGAAGATTTA
AAAGCAATTGTAAGAGCACAGCCAGATGTTATACGTTTACCTAAAACTGAAACTGCTCAAGATGTTTTAGATATGGAGAA
GATTATTGCCTCTATAGAAGAAGAAATAGGTCTTTCTATTGGAAAAACTAAAATGATGGCTGCTATAGAATCAGCCTTAG
GTGTTTTAAACGCTTATGAAATAGCAACCTCTTCAAAACGTTTAATGGGAATTGCCTTAGGTGCTGAAGACTTTGTAACT
GATATGAAAACTCATAGATCTCCTGAAGGTAATGAACTTTTTGCAGCACGTAGTCATATAATTCTAGCTTCAAGAGCAGC
TAAAATTTCAGCTTTTGATACAGTTTATTCTGATGTAAATAATGAAGAGGGCTTTATTAAGGAAGCAACATTAATAAAAC
AACTAGGTTTTGATGGAAAATCCTTAATAAATCCAAGACAAATAGACTTATTACATAAAGTCTTTGAACCTACTGAAAAA
GAAATTGATAAGGCAATAAAAATTATAGAAGCTGCTAAGGAAGCAGAAAAACGTGGCTCAGGTGTTGTATCTCTTAATGG
AAAAATGATTGATAAGCCAGTAATAGCAAGGGCAGAAAGAGTTCTTATGCTAGCTAAGGCTTCAGGAATATCATATGAAA
AGGAAGTGTAA

Upstream 100 bases:

>100_bases
TAAATGATAAGGGAGCCTTAAATTGTGTTATTGAAGCACGTATAGAAGCGGCAGTATGTAGAGCTTCAGAAATAAATGAA
TTTGATTGGGGGAATTATAA

Downstream 100 bases:

>100_bases
TTTATGGGAATCAATAGTATCAATATAAATATACCAGATGACATATTAAAAGAGAGAAAAACTGTAGAATTTAAAGGAGA
ATTCGCATTAGAACCTAAGG

Product: citrate lyase beta subunit

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPRLRRSMMFVPGSKPAMIRDCTIYGADSVMFDLEDSVSIAEKDSARRLVYHALTSMDFGDTETVVRVNALDSEFGIEDL
KAIVRAQPDVIRLPKTETAQDVLDMEKIIASIEEEIGLSIGKTKMMAAIESALGVLNAYEIATSSKRLMGIALGAEDFVT
DMKTHRSPEGNELFAARSHIILASRAAKISAFDTVYSDVNNEEGFIKEATLIKQLGFDGKSLINPRQIDLLHKVFEPTEK
EIDKAIKIIEAAKEAEKRGSGVVSLNGKMIDKPVIARAERVLMLAKASGISYEKEV

Sequences:

>Translated_296_residues
MPRLRRSMMFVPGSKPAMIRDCTIYGADSVMFDLEDSVSIAEKDSARRLVYHALTSMDFGDTETVVRVNALDSEFGIEDL
KAIVRAQPDVIRLPKTETAQDVLDMEKIIASIEEEIGLSIGKTKMMAAIESALGVLNAYEIATSSKRLMGIALGAEDFVT
DMKTHRSPEGNELFAARSHIILASRAAKISAFDTVYSDVNNEEGFIKEATLIKQLGFDGKSLINPRQIDLLHKVFEPTEK
EIDKAIKIIEAAKEAEKRGSGVVSLNGKMIDKPVIARAERVLMLAKASGISYEKEV
>Mature_295_residues
PRLRRSMMFVPGSKPAMIRDCTIYGADSVMFDLEDSVSIAEKDSARRLVYHALTSMDFGDTETVVRVNALDSEFGIEDLK
AIVRAQPDVIRLPKTETAQDVLDMEKIIASIEEEIGLSIGKTKMMAAIESALGVLNAYEIATSSKRLMGIALGAEDFVTD
MKTHRSPEGNELFAARSHIILASRAAKISAFDTVYSDVNNEEGFIKEATLIKQLGFDGKSLINPRQIDLLHKVFEPTEKE
IDKAIKIIEAAKEAEKRGSGVVSLNGKMIDKPVIARAERVLMLAKASGISYEKEV

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=297, Percent_Identity=27.9461279461279, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI87081764, Length=291, Percent_Identity=62.1993127147766, Blast_Score=355, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17557458, Length=301, Percent_Identity=27.906976744186, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 32555; Mature: 32424

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLRRSMMFVPGSKPAMIRDCTIYGADSVMFDLEDSVSIAEKDSARRLVYHALTSMDFG
CCCHHCCEEECCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
DTETVVRVNALDSEFGIEDLKAIVRAQPDVIRLPKTETAQDVLDMEKIIASIEEEIGLSI
CCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
GKTKMMAAIESALGVLNAYEIATSSKRLMGIALGAEDFVTDMKTHRSPEGNELFAARSHI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCCCEEEHHHHEE
ILASRAAKISAFDTVYSDVNNEEGFIKEATLIKQLGFDGKSLINPRQIDLLHKVFEPTEK
EEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCHHH
EIDKAIKIIEAAKEAEKRGSGVVSLNGKMIDKPVIARAERVLMLAKASGISYEKEV
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure 
PRLRRSMMFVPGSKPAMIRDCTIYGADSVMFDLEDSVSIAEKDSARRLVYHALTSMDFG
CCHHCCEEECCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
DTETVVRVNALDSEFGIEDLKAIVRAQPDVIRLPKTETAQDVLDMEKIIASIEEEIGLSI
CCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
GKTKMMAAIESALGVLNAYEIATSSKRLMGIALGAEDFVTDMKTHRSPEGNELFAARSHI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCCCEEEHHHHEE
ILASRAAKISAFDTVYSDVNNEEGFIKEATLIKQLGFDGKSLINPRQIDLLHKVFEPTEK
EEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCHHH
EIDKAIKIIEAAKEAEKRGSGVVSLNGKMIDKPVIARAERVLMLAKASGISYEKEV
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]